ATE366114T1 - Verwendung von anti-prolaktin agentien zur behandlung von krebs - Google Patents

Verwendung von anti-prolaktin agentien zur behandlung von krebs

Info

Publication number
ATE366114T1
ATE366114T1 AT99921843T AT99921843T ATE366114T1 AT E366114 T1 ATE366114 T1 AT E366114T1 AT 99921843 T AT99921843 T AT 99921843T AT 99921843 T AT99921843 T AT 99921843T AT E366114 T1 ATE366114 T1 AT E366114T1
Authority
AT
Austria
Prior art keywords
prolactin
treat cancer
agents
prolactin agents
human
Prior art date
Application number
AT99921843T
Other languages
English (en)
Inventor
Wen Y Chen
Thomas E Wagner
Original Assignee
Greenville Hospital System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26772335&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE366114(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Greenville Hospital System filed Critical Greenville Hospital System
Application granted granted Critical
Publication of ATE366114T1 publication Critical patent/ATE366114T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/2257Prolactin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT99921843T 1998-05-12 1999-05-11 Verwendung von anti-prolaktin agentien zur behandlung von krebs ATE366114T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8512898P 1998-05-12 1998-05-12
US24604199A 1999-02-05 1999-02-05

Publications (1)

Publication Number Publication Date
ATE366114T1 true ATE366114T1 (de) 2007-07-15

Family

ID=26772335

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99921843T ATE366114T1 (de) 1998-05-12 1999-05-11 Verwendung von anti-prolaktin agentien zur behandlung von krebs

Country Status (11)

Country Link
US (2) US7115556B2 (de)
EP (2) EP2316467A1 (de)
JP (4) JP5259896B2 (de)
AT (1) ATE366114T1 (de)
AU (1) AU3895299A (de)
CA (1) CA2328520C (de)
DE (1) DE69936451T2 (de)
DK (1) DK1079851T3 (de)
ES (1) ES2288777T3 (de)
PT (1) PT1079851E (de)
WO (1) WO1999058142A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004504272A (ja) * 2000-03-23 2004-02-12 グリーンビル ホスピタル システム 双機能癌治療剤
JP4149994B2 (ja) * 2002-06-12 2008-09-17 ロレアル シリコーンポリマーおよびオルガノゲル化剤によって構造化された固形のケア用および/またはメークアップ用組成物
WO2004054516A2 (en) * 2002-12-13 2004-07-01 The Ohio State University Antagonists for human prolactin
EA008866B1 (ru) 2002-12-26 2007-08-31 Маунтин Вью Фамэсьютикэлс, Инк. ПОЛИМЕРНЫЙ КОНЪЮГАТ МОДИФИКАЦИЙ ИНТЕРФЕРОНА-β, ФАРМАЦЕВТИЧЕСКИЕ ПРОДУКТЫ НА ЕГО ОСНОВЕ И СПОСОБ ИХ ПОЛУЧЕНИЯ
US8754031B2 (en) 2004-03-08 2014-06-17 Oncolix, Inc. Use of prolactin receptor antagonists in combination with an agent that inactivates the HER2/neu signaling pathway
US7507716B2 (en) * 2005-07-06 2009-03-24 Board Of Regents, The University Of Texas System Method for treating pain with prolactin antagonists
WO2008028684A2 (en) * 2006-09-08 2008-03-13 Novo Nordisk A/S Peptides with high affinity for the prolactin receptor
EP2129793A1 (de) 2007-03-20 2009-12-09 Institut National De La Sante Et De La Recherche Medicale Konstitutiv aktive mutanten des prolactin-rezeptors
US20100249029A1 (en) * 2007-07-05 2010-09-30 Novo Nordisk A/S Peptides with high affinity for the prolactin receptor
WO2009135056A2 (en) * 2008-04-30 2009-11-05 Monsanto Technology Llc Recombinant dna vectors for expression of human prolactin antagonists
JP5963443B2 (ja) * 2009-02-26 2016-08-03 オンコリックス, インコーポレイテッド がん幹細胞を可視化・排除するための組成物および方法
US8648046B2 (en) 2009-02-26 2014-02-11 Oncolix, Inc. Compositions and methods for visualizing and eliminating cancer stem cells
US8759289B2 (en) * 2010-02-03 2014-06-24 Orbis Health Solutions Llc Method for sensitizing cancer stem cells to cancer therapy
TWI641620B (zh) 2013-08-21 2018-11-21 再生元醫藥公司 抗-prlr抗體及其用途
US9545451B2 (en) 2013-08-21 2017-01-17 Regeneron Pharmaceuticals, Inc. Anti-PRLR antibodies and methods for killing PRLR-expressing cells
US10925971B2 (en) 2016-11-29 2021-02-23 Regeneron Pharmaceuticals, Inc. Methods of treating PRLR positive breast cancer

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4833516A (en) * 1987-08-03 1989-05-23 International Business Machines Corporation High density memory cell structure having a vertical trench transistor self-aligned with a vertical trench capacitor and fabrication methods therefor
US5350836A (en) 1989-10-12 1994-09-27 Ohio University Growth hormone antagonists
ATE196548T1 (de) 1991-05-10 2000-10-15 Genentech Inc Auswählen von agonisten und antagonisten von liganden
US6429186B1 (en) * 1991-05-10 2002-08-06 Genentech, Inc. Ligand antagonists for treatment of breast cancer
US5590656A (en) * 1992-09-15 1997-01-07 The Ohio State University Research Foundation Application of peptide/cell receptor kinetics utilizing radiolabeled somatostatin congeners in the in situ, in vivo detection and differentiation of neoplastic tissue
DE4231297A1 (de) * 1992-09-18 1994-03-24 Basf Ag Verfahren zur Herstellung von 3-(2'-Oxyethyl)-dihydro-2-(3H)furanonen
ES2180571T3 (es) 1993-02-19 2003-02-16 Genentech Inc Antagonistas de ligando para el tratamiento de cancer de mama.
PT754682E (pt) * 1994-04-06 2002-03-28 Nippon Shinyaku Co Ltd Derivado de aminostilbazol e medicamento
DE19718721C2 (de) * 1997-05-02 1999-10-07 Siemens Ag DRAM-Zellenanordnung und Verfahren zu deren Herstellung

Also Published As

Publication number Publication date
JP5259896B2 (ja) 2013-08-07
ES2288777T3 (es) 2008-01-16
JP2013224309A (ja) 2013-10-31
EP1079851B1 (de) 2007-07-04
JP2012020996A (ja) 2012-02-02
JP5453355B2 (ja) 2014-03-26
EP1079851A4 (de) 2004-03-17
WO1999058142A1 (en) 1999-11-18
JP2002515404A (ja) 2002-05-28
US7115556B2 (en) 2006-10-03
US20070060520A1 (en) 2007-03-15
AU3895299A (en) 1999-11-29
US20030022833A1 (en) 2003-01-30
EP1079851A1 (de) 2001-03-07
DK1079851T3 (da) 2007-09-24
WO1999058142A9 (en) 2000-02-10
JP2011079821A (ja) 2011-04-21
CA2328520A1 (en) 1999-11-18
DE69936451D1 (de) 2007-08-16
EP2316467A1 (de) 2011-05-04
DE69936451T2 (de) 2008-03-13
PT1079851E (pt) 2007-10-08
CA2328520C (en) 2013-06-25

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