DK0742796T3 - IL-3-variant-hæmatopoiesefusionsprotein - Google Patents

IL-3-variant-hæmatopoiesefusionsprotein

Info

Publication number
DK0742796T3
DK0742796T3 DK95908514T DK95908514T DK0742796T3 DK 0742796 T3 DK0742796 T3 DK 0742796T3 DK 95908514 T DK95908514 T DK 95908514T DK 95908514 T DK95908514 T DK 95908514T DK 0742796 T3 DK0742796 T3 DK 0742796T3
Authority
DK
Denmark
Prior art keywords
variant
hil
amino acid
relates
hæmatopoiesefusionsprotein
Prior art date
Application number
DK95908514T
Other languages
English (en)
Inventor
Mark Allen Abrams
Sarah Ruth Braford-Goldberg
Maire Helena Caparon
Alan Michael Easton
Peter O Olins
Kumnan Paik
Christopher S Bauer
Barbara Kure Klein
Kearn John Patrick Mc
John Warren Thomas
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Application granted granted Critical
Publication of DK0742796T3 publication Critical patent/DK0742796T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5403—IL-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/14—Lymphokine; related peptides
    • Y10S930/141—Interleukin
DK95908514T 1994-02-04 1995-01-25 IL-3-variant-hæmatopoiesefusionsprotein DK0742796T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/192,299 US5738849A (en) 1992-11-24 1994-02-04 Interleukin-3 (IL-3) variant fusion proteins, their recombinant production, and therapeutic compositions comprising them
PCT/US1995/000549 WO1995021197A1 (en) 1994-02-04 1995-01-25 Il-3 variant hematopoiesis fusion protein

Publications (1)

Publication Number Publication Date
DK0742796T3 true DK0742796T3 (da) 2003-08-11

Family

ID=22709107

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95908514T DK0742796T3 (da) 1994-02-04 1995-01-25 IL-3-variant-hæmatopoiesefusionsprotein

Country Status (13)

Country Link
US (4) US5738849A (da)
EP (2) EP0742796B1 (da)
JP (1) JPH09508524A (da)
AT (1) ATE237641T1 (da)
AU (1) AU700220B2 (da)
CA (1) CA2182483C (da)
DE (1) DE69530374T2 (da)
DK (1) DK0742796T3 (da)
ES (1) ES2197191T3 (da)
HK (1) HK1013655A1 (da)
NZ (1) NZ279624A (da)
PT (1) PT742796E (da)
WO (1) WO1995021197A1 (da)

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US7332158B2 (en) * 2002-05-29 2008-02-19 Demao Yang Compositions and treatments for myelosuppression by ex vivo activated immune cells
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ES2426194T3 (es) * 2005-08-02 2013-10-21 Planet Biotechnology, Inc. Proteínas quiméricas del receptor de toxina mejoradas y proteínas quiméricas del receptor de toxina para el tratamiento y la prevención de anthrax
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Also Published As

Publication number Publication date
EP1323737A2 (en) 2003-07-02
ES2197191T3 (es) 2004-01-01
US6074639A (en) 2000-06-13
WO1995021197A1 (en) 1995-08-10
CA2182483A1 (en) 1995-08-10
US6132991A (en) 2000-10-17
NZ279624A (en) 1998-05-27
AU700220B2 (en) 1998-12-24
ATE237641T1 (de) 2003-05-15
EP0742796B1 (en) 2003-04-16
EP1323737A3 (en) 2003-10-15
JPH09508524A (ja) 1997-09-02
CA2182483C (en) 2002-04-02
US5738849A (en) 1998-04-14
AU1680595A (en) 1995-08-21
EP0742796A1 (en) 1996-11-20
HK1013655A1 (en) 1999-09-03
PT742796E (pt) 2003-08-29
DE69530374T2 (de) 2003-12-18
DE69530374D1 (de) 2003-05-22
US5858347A (en) 1999-01-12

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