DK0730590T3 - Isoxazolin og isozazol fibrinogenreceptorantagonister - Google Patents
Isoxazolin og isozazol fibrinogenreceptorantagonisterInfo
- Publication number
- DK0730590T3 DK0730590T3 DK95901915T DK95901915T DK0730590T3 DK 0730590 T3 DK0730590 T3 DK 0730590T3 DK 95901915 T DK95901915 T DK 95901915T DK 95901915 T DK95901915 T DK 95901915T DK 0730590 T3 DK0730590 T3 DK 0730590T3
- Authority
- DK
- Denmark
- Prior art keywords
- fibrinogen receptor
- isozazole
- isoxazoline
- compounds
- receptor antagonists
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/04—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Ophthalmology & Optometry (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Vascular Medicine (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15759893A | 1993-11-24 | 1993-11-24 | |
| US23296194A | 1994-04-22 | 1994-04-22 | |
| US33792094A | 1994-11-10 | 1994-11-10 | |
| PCT/US1994/013155 WO1995014683A1 (en) | 1993-11-24 | 1994-11-14 | Novel isoxazoline and isoxazole fibrinogen receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0730590T3 true DK0730590T3 (da) | 2001-03-19 |
Family
ID=27388036
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95901915T DK0730590T3 (da) | 1993-11-24 | 1994-11-14 | Isoxazolin og isozazol fibrinogenreceptorantagonister |
Country Status (24)
| Country | Link |
|---|---|
| EP (2) | EP0970950A3 (pl) |
| JP (1) | JPH09505590A (pl) |
| KR (1) | KR100359046B1 (pl) |
| AT (1) | ATE198748T1 (pl) |
| AU (1) | AU695853B2 (pl) |
| BR (1) | BR9408137A (pl) |
| CA (1) | CA2174838A1 (pl) |
| CZ (1) | CZ141996A3 (pl) |
| DE (1) | DE69426604T2 (pl) |
| DK (1) | DK0730590T3 (pl) |
| ES (1) | ES2154326T3 (pl) |
| FI (1) | FI962184A0 (pl) |
| GR (1) | GR3035610T3 (pl) |
| HR (1) | HRP940952A2 (pl) |
| HU (1) | HUT74690A (pl) |
| IL (1) | IL111721A (pl) |
| NO (1) | NO309768B1 (pl) |
| NZ (1) | NZ276633A (pl) |
| PL (1) | PL182303B1 (pl) |
| PT (1) | PT730590E (pl) |
| RU (1) | RU2149871C1 (pl) |
| SK (1) | SK66696A3 (pl) |
| TW (1) | TW483895B (pl) |
| WO (1) | WO1995014683A1 (pl) |
Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5849736A (en) * | 1993-11-24 | 1998-12-15 | The Dupont Merck Pharmaceutical Company | Isoxazoline and isoxazole fibrinogen receptor antagonists |
| ZA963391B (en) * | 1995-05-24 | 1997-10-29 | Du Pont Merck Pharma | Isoxazoline fibrinogen receptor antagonists. |
| US5710159A (en) * | 1996-05-09 | 1998-01-20 | The Dupont Merck Pharmaceutical Company | Integrin receptor antagonists |
| IL118325A0 (en) * | 1995-05-25 | 1996-10-31 | Pont Merck And Pharmaceutical | Integrin receptor antagonists and pharmaceutical compositions containing them |
| CA2233204A1 (en) | 1995-09-29 | 1997-04-03 | Joseph A. Jakubowski | Spiro compounds as inhibitors of fibrinogen-dependent platelet aggregation |
| JPH11513382A (ja) * | 1995-10-20 | 1999-11-16 | ドクトル カルル トーマエ ゲゼルシャフト ミット ベシュレンクテル ハフツング | ５員複素環化合物、これらの化合物を含む医薬品、それらの使用及びそれらの調製方法 |
| US5939418A (en) * | 1995-12-21 | 1999-08-17 | The Dupont Merck Pharmaceutical Company | Isoxazoline, isothiazoline and pyrazoline factor Xa inhibitors |
| AU1335897A (en) * | 1995-12-21 | 1997-07-17 | Du Pont Merck Pharmaceutical Company, The | Isoxazoline, isothiazoline and pyrazoline factor xa inhibitors |
| US5760028A (en) * | 1995-12-22 | 1998-06-02 | The Dupont Merck Pharmaceutical Company | Integrin receptor antagonists |
| AU1345697A (en) * | 1995-12-22 | 1997-07-17 | Du Pont Merck Pharmaceutical Company, The | Novel integrin receptor antagonists |
| EP0888344A1 (en) * | 1996-03-15 | 1999-01-07 | The Du Pont Merck Pharmaceutical Company | Spirocycle integrin inhibitors |
| ZA972195B (en) * | 1996-03-15 | 1998-09-14 | Du Pont Merck Pharma | Spirocycle integrin inhibitors |
| US6185453B1 (en) | 1996-06-19 | 2001-02-06 | Dupont Pharmaceuticals Company | Iontophoretic delivery of integrin inhibitors |
| EP0922039A1 (en) * | 1996-08-15 | 1999-06-16 | Du Pont Pharmaceuticals Company | Cyclic carbamates and isoxazolidines as iib/iiia antagonists |
| CA2263999A1 (en) * | 1996-08-29 | 1998-03-05 | Merck & Co., Inc. | Integrin antagonists |
| US5900414A (en) * | 1996-08-29 | 1999-05-04 | Merck & Co., Inc. | Methods for administering integrin receptor antagonists |
| US5797867A (en) | 1996-09-27 | 1998-08-25 | Becton Dickinson And Company | Iontophoretic drug delivery system, including method for activating same for attachment to patient |
| US5738647A (en) | 1996-09-27 | 1998-04-14 | Becton Dickinson And Company | User activated iontophoretic device and method for activating same |
| US6187797B1 (en) | 1996-12-23 | 2001-02-13 | Dupont Pharmaceuticals Company | Phenyl-isoxazoles as factor XA Inhibitors |
| US6022977A (en) * | 1997-03-26 | 2000-02-08 | Dupont Pharmaceuticals Company | Dynamic resolution of isoxazoline thioesters to isoxazoline carboxylic acids |
| US6214834B1 (en) | 1997-03-28 | 2001-04-10 | Dupont Pharmaceuticals Company | Integrin inhibitor prodrugs |
| US6100260A (en) * | 1997-04-21 | 2000-08-08 | Sumitomo Pharmaceutical Company, Limited | Isoxazole derivatives |
| HRP980291A2 (en) | 1997-06-16 | 1999-04-30 | Lin-Hua Zhang | Crystalline roxifiban |
| US5998424A (en) | 1997-06-19 | 1999-12-07 | Dupont Pharmaceuticals Company | Inhibitors of factor Xa with a neutral P1 specificity group |
| JP2002507968A (ja) * | 1997-06-19 | 2002-03-12 | デュポン ファーマシューティカルズ カンパニー | 中性のＰ１特異性基を有するＸａ因子阻害剤 |
| US6339099B1 (en) | 1997-06-20 | 2002-01-15 | Dupont Pharmaceuticals Company | Guanidine mimics as factor Xa inhibitors |
| US5886191A (en) * | 1997-08-18 | 1999-03-23 | Dupont Pharmaceuticals Company | Amidinoindoles, amidinoazoles, and analogs thereof |
| ZA988735B (en) | 1997-10-06 | 2000-03-23 | Du Pont Pharm Co | An efficient method for the conversion of nitriles to amidines. |
| ZA99168B (en) * | 1998-01-16 | 2000-07-11 | Du Pont Pharm Co | Pharmaceutical formulations and processes for their preparation. |
| DE69920888T2 (de) | 1998-03-27 | 2006-02-02 | Bristol-Myers Squibb Pharma Co. | Disubstituierte pyrazoline und triazoline als faktor xa inhibitoren |
| WO2000000481A1 (en) * | 1998-06-29 | 2000-01-06 | Du Pont Pharmaceuticals Company | Cyclic carbamates and isoxazolidines as iib/iiia antagonists |
| AU1735200A (en) | 1998-11-18 | 2000-06-05 | Du Pont Pharmaceuticals Company | Novel isoxazoline fibrinogen receptor antagonists |
| US6319937B1 (en) | 1998-11-18 | 2001-11-20 | Dupont Pharmaceuticals Company | Isoxazoline fibrinogen receptor antagonists |
| US6339083B1 (en) | 1998-12-14 | 2002-01-15 | Bayer Aktiengesellschaft | Multiheterocyclic pharmAceuticals |
| JP2003526617A (ja) | 1999-03-11 | 2003-09-09 | デュポン ファーマシューティカルズ カンパニー | 種々の血栓塞栓性障害の予防および治療のための併用療法を提供する低分子量へパリンと血小板凝集阻害剤との相乗効果 |
| WO2000053264A1 (en) * | 1999-03-11 | 2000-09-14 | Du Pont Pharmaceuticals Company | Treatment of thrombosis by combined use of a factor xa inhibitor and aspirin, tissue plasminogen activator (tpa), a gpiib/iiia antagonist, low molecular weight heparin or heparin |
| US6794412B1 (en) | 1999-03-11 | 2004-09-21 | Bristol-Myers Squibb Pharma Company | Treatment of thrombosis by combined use of a factor Xa inhibitor and aspirin |
| DE60003025T2 (de) | 1999-04-02 | 2004-03-18 | Bristol-Myers Squibb Pharma Co. | Arylsulfonyle als faktor xa inhibitoren |
| EP1455858A4 (en) | 2001-11-26 | 2006-02-15 | Genentech Inc | CATHETER COMPOSITION AND ITS USES |
| EP1677783A2 (en) | 2003-10-08 | 2006-07-12 | Nicholas Piramal India Limited | Fibrinogen receptor antagonists and their use |
| SI1731512T1 (sl) | 2004-03-05 | 2015-01-30 | Nissan Chemical Industries, Ltd. | Z izoksazolinom substituirana benzamidna spojina in sredstvo za uravnavanje škodljivih organizmov |
| RU2416606C2 (ru) * | 2004-06-17 | 2011-04-20 | Инфинити Дискавери, Инк. | Соединения и способы для ингибирования взаимодействия bcl белков с компонентами по связыванию |
| US7842815B2 (en) | 2004-06-17 | 2010-11-30 | Infinity Pharmaceuticals, Inc. | Compounds and methods for inhibiting the interaction of BCL proteins with binding partners |
| CA2583267A1 (en) | 2004-10-12 | 2006-04-27 | Amgen Inc. | Novel b1 bradykinin receptor antagonists |
| WO2006044355A1 (en) | 2004-10-13 | 2006-04-27 | Amgen Inc. | Triazoles and their use as bradykinin b1 receptor antagonists |
| EP1932836B1 (en) | 2005-09-02 | 2013-11-06 | Nissan Chemical Industries, Ltd. | Isoxazoline-substituted benzamide compound and harmful organism-controlling agent |
| TWI403320B (zh) | 2005-12-16 | 2013-08-01 | Infinity Discovery Inc | 用於抑制ｂｃｌ蛋白和結合夥伴間之交互作用的化合物及方法 |
| AU2006337137B2 (en) | 2005-12-29 | 2012-06-14 | Tersera Therapeutics Llc | Multicyclic amino acid derivatives and methods of their use |
| TWI389895B (zh) | 2006-08-21 | 2013-03-21 | Infinity Discovery Inc | 抑制ｂｃｌ蛋白質與結合夥伴間之交互作用的化合物及方法 |
| EP2086571A2 (en) | 2006-11-07 | 2009-08-12 | Genentech, Inc. | Tissue plasminogen activator variant uses |
| MX2011010647A (es) | 2009-04-07 | 2012-02-21 | Astrazeneca Ab | Analogos de isoxasol-3 (2h)-ona como agentes terapeuticos. |
| US8729263B2 (en) | 2012-08-13 | 2014-05-20 | Novartis Ag | 1,4-disubstituted pyridazine analogs there of and methods for treating SMN-deficiency-related conditions |
| CN105636953B (zh) | 2013-07-31 | 2018-01-02 | 诺华股份有限公司 | 1,4‑二取代的哒嗪衍生物及其用于治疗与smn缺乏相关的病症的用途 |
| DE102014108210A1 (de) | 2014-06-11 | 2015-12-17 | Dietrich Gulba | Rodentizid |
| WO2019200202A1 (en) * | 2018-04-12 | 2019-10-17 | Morphic Therapeutic, Inc. | Antagonists of human integrin (alpha4)(beta7) |
| EP4070658A1 (de) | 2021-04-06 | 2022-10-12 | BIORoxx GmbH | Verwendung von blutgerinnungshemmenden verbindungen als rodentizide |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL99537A (en) * | 1990-09-27 | 1995-11-27 | Merck & Co Inc | Fibrinogen receptor antagonists and pharmaceutical preparations containing them |
| HUT68769A (en) * | 1991-05-07 | 1995-07-28 | Merck & Co Inc | FIBRINOGéN RECEPTOR ANTAGONIST COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AS EFFECTIVE SUBSTANCE |
| DE4124942A1 (de) * | 1991-07-27 | 1993-01-28 | Thomae Gmbh Dr K | 5-gliedrige heterocyclen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| US5227490A (en) * | 1992-02-21 | 1993-07-13 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| JP3240534B2 (ja) * | 1992-06-05 | 2001-12-17 | コニカ株式会社 | 画像形成方法 |
-
1994
- 1994-11-14 RU RU96113095/04A patent/RU2149871C1/ru not_active IP Right Cessation
- 1994-11-14 JP JP7515117A patent/JPH09505590A/ja active Pending
- 1994-11-14 DK DK95901915T patent/DK0730590T3/da active
- 1994-11-14 CZ CZ961419A patent/CZ141996A3/cs unknown
- 1994-11-14 BR BR9408137A patent/BR9408137A/pt not_active Application Discontinuation
- 1994-11-14 HU HU9601414A patent/HUT74690A/hu unknown
- 1994-11-14 WO PCT/US1994/013155 patent/WO1995014683A1/en not_active Application Discontinuation
- 1994-11-14 ES ES95901915T patent/ES2154326T3/es not_active Expired - Lifetime
- 1994-11-14 KR KR1019960702749A patent/KR100359046B1/ko not_active IP Right Cessation
- 1994-11-14 PL PL94314591A patent/PL182303B1/pl unknown
- 1994-11-14 DE DE69426604T patent/DE69426604T2/de not_active Expired - Fee Related
- 1994-11-14 EP EP99119541A patent/EP0970950A3/en not_active Withdrawn
- 1994-11-14 AU AU10980/95A patent/AU695853B2/en not_active Ceased
- 1994-11-14 SK SK666-96A patent/SK66696A3/sk unknown
- 1994-11-14 NZ NZ276633A patent/NZ276633A/en unknown
- 1994-11-14 PT PT95901915T patent/PT730590E/pt unknown
- 1994-11-14 CA CA002174838A patent/CA2174838A1/en not_active Abandoned
- 1994-11-14 EP EP95901915A patent/EP0730590B1/en not_active Expired - Lifetime
- 1994-11-14 AT AT95901915T patent/ATE198748T1/de not_active IP Right Cessation
- 1994-11-21 IL IL11172194A patent/IL111721A/xx active IP Right Grant
- 1994-11-22 TW TW083110865A patent/TW483895B/zh not_active IP Right Cessation
- 1994-11-23 HR HR08/337,920A patent/HRP940952A2/hr not_active Application Discontinuation
-
1996
- 1996-05-23 FI FI962184A patent/FI962184A0/fi unknown
- 1996-05-23 NO NO962096A patent/NO309768B1/no not_active IP Right Cessation
-
2001
- 2001-03-20 GR GR20010400456T patent/GR3035610T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE198748T1 (de) | 2001-02-15 |
| JPH09505590A (ja) | 1997-06-03 |
| NZ276633A (en) | 1998-04-27 |
| ES2154326T3 (es) | 2001-04-01 |
| HUT74690A (en) | 1997-01-28 |
| PL182303B1 (en) | 2001-12-31 |
| HU9601414D0 (en) | 1996-07-29 |
| EP0970950A2 (en) | 2000-01-12 |
| GR3035610T3 (en) | 2001-06-29 |
| CZ141996A3 (en) | 1996-11-13 |
| EP0730590A1 (en) | 1996-09-11 |
| PT730590E (pt) | 2001-05-31 |
| KR100359046B1 (ko) | 2003-08-02 |
| PL314591A1 (en) | 1996-09-16 |
| BR9408137A (pt) | 1997-08-12 |
| EP0730590B1 (en) | 2001-01-17 |
| KR960705794A (ko) | 1996-11-08 |
| RU2149871C1 (ru) | 2000-05-27 |
| DE69426604D1 (de) | 2001-02-22 |
| HRP940952A2 (en) | 1997-04-30 |
| FI962184A (fi) | 1996-05-23 |
| TW483895B (en) | 2002-04-21 |
| NO962096L (no) | 1996-05-23 |
| NO309768B1 (no) | 2001-03-26 |
| WO1995014683A1 (en) | 1995-06-01 |
| EP0970950A3 (en) | 2000-04-05 |
| CA2174838A1 (en) | 1995-06-01 |
| IL111721A (en) | 2000-06-01 |
| IL111721A0 (en) | 1995-01-24 |
| AU695853B2 (en) | 1998-08-27 |
| NO962096D0 (no) | 1996-05-23 |
| AU1098095A (en) | 1995-06-13 |
| DE69426604T2 (de) | 2001-05-10 |
| FI962184A0 (fi) | 1996-05-23 |
| SK66696A3 (en) | 1996-11-06 |
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