DK0719146T3 - Hidtil ukendt metode til administrering af progesteron samt virkning deraf - Google Patents

Hidtil ukendt metode til administrering af progesteron samt virkning deraf

Info

Publication number
DK0719146T3
DK0719146T3 DK94928089T DK94928089T DK0719146T3 DK 0719146 T3 DK0719146 T3 DK 0719146T3 DK 94928089 T DK94928089 T DK 94928089T DK 94928089 T DK94928089 T DK 94928089T DK 0719146 T3 DK0719146 T3 DK 0719146T3
Authority
DK
Denmark
Prior art keywords
progesterone
serum
administration
effect
low levels
Prior art date
Application number
DK94928089T
Other languages
Danish (da)
English (en)
Inventor
Joseph Bologna William
Leslie Levine Howard
Original Assignee
Columbia Lab Bermuda Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22402302&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0719146(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Columbia Lab Bermuda Ltd filed Critical Columbia Lab Bermuda Ltd
Application granted granted Critical
Publication of DK0719146T3 publication Critical patent/DK0719146T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK94928089T 1993-09-15 1994-09-13 Hidtil ukendt metode til administrering af progesteron samt virkning deraf DK0719146T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/122,371 US5543150A (en) 1993-09-15 1993-09-15 Method of progesterone delivery and affect thereof
PCT/US1994/010270 WO1995007699A1 (en) 1993-09-15 1994-09-13 Novel method of progesterone delivery and affect thereof

Publications (1)

Publication Number Publication Date
DK0719146T3 true DK0719146T3 (da) 1999-08-23

Family

ID=22402302

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94928089T DK0719146T3 (da) 1993-09-15 1994-09-13 Hidtil ukendt metode til administrering af progesteron samt virkning deraf

Country Status (27)

Country Link
US (1) US5543150A (es)
EP (1) EP0719146B1 (es)
JP (1) JP3143474B2 (es)
KR (1) KR100278553B1 (es)
AT (1) ATE174796T1 (es)
BR (1) BR9407475A (es)
CA (1) CA2171939C (es)
CO (1) CO4290332A1 (es)
DE (1) DE69415543T2 (es)
DK (1) DK0719146T3 (es)
ES (1) ES2126783T3 (es)
FI (1) FI115444B (es)
GR (1) GR3029314T3 (es)
HU (1) HU221583B (es)
IL (1) IL110972A (es)
LT (1) LT4072B (es)
LV (1) LV11527B (es)
MA (1) MA23329A1 (es)
MY (1) MY111484A (es)
NO (1) NO308585B1 (es)
NZ (1) NZ273816A (es)
PE (1) PE50795A1 (es)
PH (1) PH30813A (es)
RU (1) RU2148393C1 (es)
UA (1) UA37244C2 (es)
WO (1) WO1995007699A1 (es)
ZA (1) ZA947073B (es)

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US6248358B1 (en) * 1998-08-25 2001-06-19 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets and methods of making and using the same
US20040234606A1 (en) * 1997-09-12 2004-11-25 Levine Howard L. Localized vaginal delivery without detrimental blood levels
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CA2316296A1 (en) * 1997-10-10 1999-04-22 Imperial College Of Science, Technology And Medicine Use of csaidtm compounds for the management of uterine contractions
US6306914B1 (en) * 1997-10-21 2001-10-23 Columbia Laboratories, Inc. Progestin therapy for maintaining amenorrhea
WO1999059595A1 (en) * 1998-05-20 1999-11-25 Wiley Teresa S Progesterone treatment of cancer
IL127129A (en) * 1998-11-18 2004-06-01 Ferring Bv Method for preparation of progesterone tablets for vaginal delivery and tablets so prepared
US20070178139A1 (en) * 1998-11-18 2007-08-02 Yankov Vladimir I Vaginally administratable progesterone-containing tablets and method for preparing same
US6479045B2 (en) 1999-12-22 2002-11-12 Columbia Laboratories, Inc. Vaginal pH buffering for preventing miscarriage and premature labor, by treating or preventing bacterial vaginosis
US6544553B1 (en) 1999-12-28 2003-04-08 Watson Pharmaceuticals, Inc. Dosage forms and methods for oral delivery of progesterone
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UA90095C2 (en) * 2003-09-03 2010-04-12 Мискон Трейдинг С.А. Method for the treatment of endometriosis
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CA2612380C (en) * 2005-06-16 2017-06-06 Warner Chilcott Company, Inc. Estrogen compositions for vaginal administration
KR20090029237A (ko) * 2006-06-02 2009-03-20 피어 트리 파머슈티칼스 인코포레이티드 위축성 질염을 치료하는 방법
US8828981B2 (en) 2007-02-06 2014-09-09 George Creasy Progesterone for the treatment or prevention of spontaneous preterm birth
ES2310968B1 (es) 2007-06-25 2010-02-08 Italfarmaco, S.A. Uso de estriol en bajas dosis.
JP2010539245A (ja) * 2007-09-14 2010-12-16 日東電工株式会社 薬物担体
GB0723882D0 (en) * 2007-12-07 2008-01-23 Univ Leicester Methods for the detection of a threatened miscarriage
SI2359807T1 (sl) 2008-02-04 2017-10-30 Ferring B.V. Monolitni intravaginalni obroč, ki vsebuje progesteron ter postopki za njegovo izdelavo in uporabo
US9107696B2 (en) * 2008-08-06 2015-08-18 Emory University Method of embryo transfer that eliminates transferred air while hormonally inducing implantation and apparatus
ES2344673B1 (es) 2008-08-07 2011-05-03 Italfarmaco, S.A. Uso de estriol en la preparacion de una formulacion farmaceutica parael tratamiento de atrofia vaginal en mujeres con riesgo de potologiatumoral.
US8421747B2 (en) 2008-09-24 2013-04-16 Microsoft Corporation Object detection and user settings
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CN107260745A (zh) * 2010-03-22 2017-10-20 利普生物药剂公司 用于抗孕酮的非毒性递送的组合物和方法
US9375437B2 (en) 2010-06-18 2016-06-28 Lipocine Inc. Progesterone containing oral dosage forms and kits
US8435972B2 (en) 2010-09-02 2013-05-07 Emory University Method for the treatment of central nervous system cancers and compositions related thereto
JP6010120B2 (ja) * 2011-07-15 2016-10-19 ウニベルシテイト ヘント 膣内送達システム
US8951996B2 (en) 2011-07-28 2015-02-10 Lipocine Inc. 17-hydroxyprogesterone ester-containing oral compositions and related methods
CA2856520C (en) 2011-11-23 2021-04-06 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
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EP2806742B1 (en) * 2012-01-26 2019-03-27 TherapeuticsMD, Inc. Transdermal hormone replacement therapies
ES2701400T3 (es) 2012-05-31 2019-02-22 Repros Therapeutics Inc Formulaciones para la administración vaginal de antiprogestinas
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
JP6343619B2 (ja) 2012-11-02 2018-06-13 レプロス セラピューティクス インコーポレイティド プロゲステロン依存性病態を処置する方法およびその組成物
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
CN103239389A (zh) * 2013-06-03 2013-08-14 南京泽恒医药技术开发有限公司 一种治疗先兆性流产的黄体酮缓释凝胶的制备方法
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CN107847506A (zh) 2015-06-22 2018-03-27 来普卡公司 含17‑羟基孕酮酯的口服组合物和相关方法
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Also Published As

Publication number Publication date
JP3143474B2 (ja) 2001-03-07
HU221583B (hu) 2002-11-28
JPH09502724A (ja) 1997-03-18
NO961044L (no) 1996-05-14
WO1995007699A1 (en) 1995-03-23
PE50795A1 (es) 1996-01-19
EP0719146B1 (en) 1998-12-23
ZA947073B (en) 1995-05-02
KR100278553B1 (ko) 2001-01-15
NO308585B1 (no) 2000-10-02
AU689133B2 (en) 1998-03-26
IL110972A0 (en) 1994-11-28
AU7726194A (en) 1995-04-03
GR3029314T3 (en) 1999-05-28
NZ273816A (en) 2007-09-28
FI115444B (fi) 2005-05-13
NO961044D0 (no) 1996-03-14
LT4072B (en) 1996-11-25
US5543150A (en) 1996-08-06
LT96027A (en) 1996-07-25
HU9600669D0 (en) 1996-05-28
CO4290332A1 (es) 1996-04-17
UA37244C2 (uk) 2001-05-15
HUT76824A (en) 1997-11-28
LV11527A (lv) 1996-10-20
ATE174796T1 (de) 1999-01-15
BR9407475A (pt) 1996-11-12
LV11527B (en) 1997-02-20
CA2171939C (en) 2002-01-01
IL110972A (en) 1998-03-10
MY111484A (en) 2000-06-30
DE69415543D1 (de) 1999-02-04
FI961221A (fi) 1996-05-14
EP0719146A1 (en) 1996-07-03
ES2126783T3 (es) 1999-04-01
CA2171939A1 (en) 1995-03-23
MA23329A1 (fr) 1995-04-01
PH30813A (en) 1997-10-17
DE69415543T2 (de) 1999-06-17
RU2148393C1 (ru) 2000-05-10
FI961221A0 (fi) 1996-03-15

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