DK0705272T3 - Særlig fremgangsmåde til fremstilling af 17beta-substituerede 4-azaandrostanderivater - Google Patents

Særlig fremgangsmåde til fremstilling af 17beta-substituerede 4-azaandrostanderivater

Info

Publication number
DK0705272T3
DK0705272T3 DK93913459T DK93913459T DK0705272T3 DK 0705272 T3 DK0705272 T3 DK 0705272T3 DK 93913459 T DK93913459 T DK 93913459T DK 93913459 T DK93913459 T DK 93913459T DK 0705272 T3 DK0705272 T3 DK 0705272T3
Authority
DK
Denmark
Prior art keywords
cir
general formula
group
substituted
preparing
Prior art date
Application number
DK93913459T
Other languages
English (en)
Inventor
Judit Horvath
Janos Szeles
Laszlo Kollar
Zoltan Tuba
Gabor Balogh
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Application granted granted Critical
Publication of DK0705272T3 publication Critical patent/DK0705272T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
    • C07J73/005—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by nitrogen as hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK93913459T 1993-06-24 1993-06-24 Særlig fremgangsmåde til fremstilling af 17beta-substituerede 4-azaandrostanderivater DK0705272T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/HU1993/000039 WO1995000531A1 (en) 1993-06-24 1993-06-24 NOVEL PROCESS FOR PREPARING 17β-SUBSTITUTED 4-AZAANDROSTANE DERIVATIVES

Publications (1)

Publication Number Publication Date
DK0705272T3 true DK0705272T3 (da) 2002-05-27

Family

ID=10982846

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93913459T DK0705272T3 (da) 1993-06-24 1993-06-24 Særlig fremgangsmåde til fremstilling af 17beta-substituerede 4-azaandrostanderivater

Country Status (14)

Country Link
EP (1) EP0705272B1 (da)
JP (1) JP3253088B2 (da)
KR (1) KR100279567B1 (da)
AT (1) ATE215092T1 (da)
AU (1) AU681585B2 (da)
CA (1) CA2166090C (da)
DE (1) DE69331763T2 (da)
DK (1) DK0705272T3 (da)
ES (1) ES2173889T3 (da)
FI (1) FI956236A (da)
PT (1) PT705272E (da)
RU (1) RU2109746C1 (da)
UA (1) UA41933C2 (da)
WO (1) WO1995000531A1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU212459B (en) * 1992-10-02 1996-06-28 Richter Gedeon Vegyeszet Process for producing new 17-beta-substituted 4-aza-androstane-derivatives and pharmaceutical compositions containing them
ES2153789B1 (es) * 1999-07-05 2001-10-16 Raga Consultores S L Procedimiento para la obtencion de 178-(n-terc-butlcarbamoil)-3-ona-4-aza-esteroides
WO2004100874A2 (en) 2003-05-07 2004-11-25 Merck & Co., Inc. Androgen receptor modulators and methods of use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU527030B2 (en) * 1978-04-13 1983-02-10 Merck & Co., Inc. 4-aza-17-substituted-5a-androstan-3-ones
NZ211145A (en) * 1984-02-27 1988-10-28 Merck & Co Inc 4-aza-5-alpha-androst-1-en-3-ones and pharmaceutical compositions
US5120847A (en) * 1990-08-27 1992-06-09 Merck & Co., Inc. Process for iodinating or brominating the α-methylenic carbon of a secondary amide
GB9216329D0 (en) * 1992-07-31 1992-09-16 Erba Carlo Spa 17beta-substituted 4-aza-5alpha-androstan-3-one derivatives
GB9216284D0 (en) * 1992-07-31 1992-09-16 Erba Carlo Spa Fluorinated 17beta-substituted 4-aza-5alpha-androstane-3-one derivatives

Also Published As

Publication number Publication date
FI956236A0 (fi) 1995-12-22
PT705272E (pt) 2002-07-31
ATE215092T1 (de) 2002-04-15
DE69331763D1 (de) 2002-05-02
UA41933C2 (uk) 2001-10-15
RU2109746C1 (ru) 1998-04-27
CA2166090A1 (en) 1995-01-05
CA2166090C (en) 2006-01-24
AU681585B2 (en) 1997-09-04
JP3253088B2 (ja) 2002-02-04
AU4352693A (en) 1995-01-17
KR100279567B1 (ko) 2001-03-02
WO1995000531A1 (en) 1995-01-05
FI956236A (fi) 1995-12-22
DE69331763T2 (de) 2002-10-02
EP0705272A1 (en) 1996-04-10
ES2173889T3 (es) 2002-11-01
EP0705272B1 (en) 2002-03-27
JPH08511796A (ja) 1996-12-10
KR960703133A (ko) 1996-06-19

Similar Documents

Publication Publication Date Title
NO965193D0 (no) Aminalkoholderivat og fremgangsmåte for fremstilling derav
KR930703233A (ko) 지방족 카르복실산 할로메틸 에스테르의 제조방법
TW348175B (en) Process for the preparation of biphenyl derivatives
HUP0202437A2 (hu) Új eljárás (2S,3aS,7aS)-1-[(S)-alanil]oktahidro-1H-indol-2-karbonsav vegyületek előállítására és ezek alkalmazása perindopril előállítására
DK0705272T3 (da) Særlig fremgangsmåde til fremstilling af 17beta-substituerede 4-azaandrostanderivater
AU6691400A (en) Process for preparing esterquats
JPH07503942A (ja) ペプチド合成に使用するための保護されたホスホノアルキルフェニルアラニン化合物
AU9116382A (en) Production of acetic anhydride, acetic acid, ethylidene diacetate
NO20002214L (no) FremgangsmÕte for syntese av pyrrolaminer
FI961680A (fi) Menetelmä epäsymmetrisesti substituoitujen triatsiinien valmistamiseksi
DE69513408T2 (de) Ein verbessertes verfahren für die herstellung von seitenketten-derivaten von cyclohexapeptidyl-lipopeptiden
TW326444B (en) An improved process for producing 4-hydroxy-2-pyrrolidone
KR930012741A (ko) 4-히드록시메틸테트라히드로피란의 제조방법
ATE156477T1 (de) Verfahren zur enantioselektiven synthese von 2(r)-benzylbernsteinsäuremonoamid-derivaten
ATE332293T1 (de) Verfahren zur herstellung von aryltriazolinonen
HUP9902604A1 (hu) Fluortartalmú karbonsavszármazékok, eljárás azok előállítására
ES2137268T3 (es) Procedimiento para la sintesis estereoselectiva de acidos 2-sulfonilmetilpropionicos sustituidos en posicion 3 asi como productos intermedios.
YU65092A (sh) Postupak za proizvodnju sukcinilholin-halogenida
KR960022468A (ko) 클로로메틸피리딘의 제조방법
JPS61178999A (ja) 有機金化合物
US5587510A (en) (S)-2-aralkyl-3-chloropropionic acid and process for the preparation thereof
DE69331764D1 (de) 17-halogen-4-azaandrosten-derivate und verfahren zu ihrer herstellung
RU96100766A (ru) НОВЫЙ СПОСОБ ПОЛУЧЕНИЯ ПРОИЗВОДНЫХ 17β- ЗАМЕЩЕННОГО 4-АЗААНДРОСТАНА
JPH03141251A (ja) １―メチルメルカプト―１―ベンゾイル―２―（ｎ，ｎ―ジメチルアミノ）エテン誘導体およびその製造法
KR960017633A (ko) 4-아미노페닐-2-아세톡시에틸설폰의 제조방법