ES2137268T3 - Procedimiento para la sintesis estereoselectiva de acidos 2-sulfonilmetilpropionicos sustituidos en posicion 3 asi como productos intermedios. - Google Patents
Procedimiento para la sintesis estereoselectiva de acidos 2-sulfonilmetilpropionicos sustituidos en posicion 3 asi como productos intermedios.Info
- Publication number
- ES2137268T3 ES2137268T3 ES93921894T ES93921894T ES2137268T3 ES 2137268 T3 ES2137268 T3 ES 2137268T3 ES 93921894 T ES93921894 T ES 93921894T ES 93921894 T ES93921894 T ES 93921894T ES 2137268 T3 ES2137268 T3 ES 2137268T3
- Authority
- ES
- Spain
- Prior art keywords
- sulfonyl
- procedure
- well
- intermediate products
- stereoselective synthesis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/56—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C315/00—Preparation of sulfones; Preparation of sulfoxides
- C07C315/02—Preparation of sulfones; Preparation of sulfoxides by formation of sulfone or sulfoxide groups by oxidation of sulfides, or by formation of sulfone groups by oxidation of sulfoxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C315/00—Preparation of sulfones; Preparation of sulfoxides
- C07C315/04—Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
LOS COMPUESTOS DE LA FORMULA (I) SE ELABORAN EN UN PROCESO MULTIACTIVO, A PARTIR DE LOS COMPUESTOS DE LAS FORMULAS (II) : R1 - SH Y (III), DONDE LOS SUSTITUYENTES R1, R2 Y R3 TIENEN LOS SIGNIFICADOS CONOCIDOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4233100A DE4233100A1 (de) | 1992-10-01 | 1992-10-01 | Verfahren zur stereoselektiven Synthese von 3-substituierten 2-Sulfonylmethylpropionsäuren sowie Zwischenprodukte |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2137268T3 true ES2137268T3 (es) | 1999-12-16 |
Family
ID=6469439
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES93921894T Expired - Lifetime ES2137268T3 (es) | 1992-10-01 | 1993-09-30 | Procedimiento para la sintesis estereoselectiva de acidos 2-sulfonilmetilpropionicos sustituidos en posicion 3 asi como productos intermedios. |
Country Status (11)
Country | Link |
---|---|
US (1) | US5684185A (es) |
EP (1) | EP0662952B1 (es) |
JP (1) | JPH08501781A (es) |
AT (1) | ATE183737T1 (es) |
AU (1) | AU5110393A (es) |
CA (1) | CA2146142A1 (es) |
DE (2) | DE4233100A1 (es) |
DK (1) | DK0662952T3 (es) |
ES (1) | ES2137268T3 (es) |
GR (1) | GR3031695T3 (es) |
WO (1) | WO1994007850A1 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UA48262C2 (uk) * | 1996-09-27 | 2002-08-15 | Фармація Енд Апджон Компані | <font face="Symbol">b</font>-СУЛЬФОНІЛ ГІДРОКСАМОВІ КИСЛОТИ ЯК ІНГІБІТОРИ МАТРИЧНИХ МЕТАЛОПРОТЕЇНАЗ, ПРОМІЖНА СПОЛУКА ТА ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ |
FR2772027B1 (fr) * | 1997-12-10 | 2000-02-04 | Fournier Ind & Sante | Procede de preparation asymetrique de derives de l'acide 2-mercaptomethyl-3-phenyl-propanoique, utilisation pour synthese de principes actifs chiraux |
US6900218B2 (en) * | 2001-05-03 | 2005-05-31 | Galileo Pharmaceuticals, Inc. | Pyruvate derivatives |
US7196207B2 (en) | 2002-07-24 | 2007-03-27 | Mitsui Chemicals, Inc. | Method for producing 2-alkyl-3-aminothiophene derivative |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4758584A (en) * | 1987-02-05 | 1988-07-19 | Ciba-Geigy Corporation | Antihypertensive 5-amino-4-hydroxyvaleryl derivatives substituted by sulphur-containing groups |
DE3856166T2 (de) * | 1987-09-29 | 1998-08-06 | Banyu Pharma Co Ltd | N-Acylaminosäurederivate und deren Verwendung |
US5095031A (en) * | 1990-08-20 | 1992-03-10 | Abbott Laboratories | Indole derivatives which inhibit leukotriene biosynthesis |
DE4233099A1 (de) * | 1992-10-01 | 1994-04-07 | Hoechst Ag | Verfahren zur stereoselektiven Synthese von 3-substituierten 2-Thiomethylpropionsäuren |
-
1992
- 1992-10-01 DE DE4233100A patent/DE4233100A1/de not_active Withdrawn
-
1993
- 1993-09-30 WO PCT/EP1993/002674 patent/WO1994007850A1/de active IP Right Grant
- 1993-09-30 JP JP6508713A patent/JPH08501781A/ja active Pending
- 1993-09-30 ES ES93921894T patent/ES2137268T3/es not_active Expired - Lifetime
- 1993-09-30 EP EP93921894A patent/EP0662952B1/de not_active Expired - Lifetime
- 1993-09-30 US US08/411,832 patent/US5684185A/en not_active Expired - Fee Related
- 1993-09-30 AT AT93921894T patent/ATE183737T1/de not_active IP Right Cessation
- 1993-09-30 AU AU51103/93A patent/AU5110393A/en not_active Abandoned
- 1993-09-30 DE DE59309749T patent/DE59309749D1/de not_active Expired - Fee Related
- 1993-09-30 DK DK93921894T patent/DK0662952T3/da active
- 1993-09-30 CA CA002146142A patent/CA2146142A1/en not_active Abandoned
-
1999
- 1999-11-03 GR GR990402786T patent/GR3031695T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0662952A1 (de) | 1995-07-19 |
ATE183737T1 (de) | 1999-09-15 |
GR3031695T3 (en) | 2000-02-29 |
DK0662952T3 (da) | 2000-03-13 |
CA2146142A1 (en) | 1994-04-14 |
US5684185A (en) | 1997-11-04 |
WO1994007850A1 (de) | 1994-04-14 |
DE4233100A1 (de) | 1994-04-07 |
DE59309749D1 (de) | 1999-09-30 |
AU5110393A (en) | 1994-04-26 |
JPH08501781A (ja) | 1996-02-27 |
EP0662952B1 (de) | 1999-08-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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