DE69331763T2 - Neues verfahren zum herstellen von 17 beta-substituierten 4-azaandrostan-derivaten - Google Patents

Neues verfahren zum herstellen von 17 beta-substituierten 4-azaandrostan-derivaten

Info

Publication number
DE69331763T2
DE69331763T2 DE69331763T DE69331763T DE69331763T2 DE 69331763 T2 DE69331763 T2 DE 69331763T2 DE 69331763 T DE69331763 T DE 69331763T DE 69331763 T DE69331763 T DE 69331763T DE 69331763 T2 DE69331763 T2 DE 69331763T2
Authority
DE
Germany
Prior art keywords
cir
general formula
group
beta
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69331763T
Other languages
English (en)
Other versions
DE69331763D1 (de
Inventor
Zoltan Tuba
Judit Horvath
Janos Szeles
Laszl Kollar
Gabor Balogh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Application granted granted Critical
Publication of DE69331763D1 publication Critical patent/DE69331763D1/de
Publication of DE69331763T2 publication Critical patent/DE69331763T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
    • C07J73/005—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by nitrogen as hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE69331763T 1993-06-24 1993-06-24 Neues verfahren zum herstellen von 17 beta-substituierten 4-azaandrostan-derivaten Expired - Lifetime DE69331763T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/HU1993/000039 WO1995000531A1 (en) 1993-06-24 1993-06-24 NOVEL PROCESS FOR PREPARING 17β-SUBSTITUTED 4-AZAANDROSTANE DERIVATIVES

Publications (2)

Publication Number Publication Date
DE69331763D1 DE69331763D1 (de) 2002-05-02
DE69331763T2 true DE69331763T2 (de) 2002-10-02

Family

ID=10982846

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69331763T Expired - Lifetime DE69331763T2 (de) 1993-06-24 1993-06-24 Neues verfahren zum herstellen von 17 beta-substituierten 4-azaandrostan-derivaten

Country Status (14)

Country Link
EP (1) EP0705272B1 (de)
JP (1) JP3253088B2 (de)
KR (1) KR100279567B1 (de)
AT (1) ATE215092T1 (de)
AU (1) AU681585B2 (de)
CA (1) CA2166090C (de)
DE (1) DE69331763T2 (de)
DK (1) DK0705272T3 (de)
ES (1) ES2173889T3 (de)
FI (1) FI956236A0 (de)
PT (1) PT705272E (de)
RU (1) RU2109746C1 (de)
UA (1) UA41933C2 (de)
WO (1) WO1995000531A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU212459B (en) * 1992-10-02 1996-06-28 Richter Gedeon Vegyeszet Process for producing new 17-beta-substituted 4-aza-androstane-derivatives and pharmaceutical compositions containing them
ES2153789B1 (es) * 1999-07-05 2001-10-16 Raga Consultores S L Procedimiento para la obtencion de 178-(n-terc-butlcarbamoil)-3-ona-4-aza-esteroides
CN1784236A (zh) 2003-05-07 2006-06-07 麦克公司 雄激素受体调节剂及其使用方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU527030B2 (en) * 1978-04-13 1983-02-10 Merck & Co., Inc. 4-aza-17-substituted-5a-androstan-3-ones
IL74365A (en) * 1984-02-27 1990-07-26 Merck & Co Inc 17beta-(n-t.-butylcarbamoyl)-4-aza-5alpha-androst-1-en-3-one and pharmaceutical compositions containing it
US5120847A (en) * 1990-08-27 1992-06-09 Merck & Co., Inc. Process for iodinating or brominating the α-methylenic carbon of a secondary amide
GB9216284D0 (en) * 1992-07-31 1992-09-16 Erba Carlo Spa Fluorinated 17beta-substituted 4-aza-5alpha-androstane-3-one derivatives
GB9216329D0 (en) * 1992-07-31 1992-09-16 Erba Carlo Spa 17beta-substituted 4-aza-5alpha-androstan-3-one derivatives

Also Published As

Publication number Publication date
WO1995000531A1 (en) 1995-01-05
EP0705272B1 (de) 2002-03-27
JPH08511796A (ja) 1996-12-10
RU2109746C1 (ru) 1998-04-27
ATE215092T1 (de) 2002-04-15
EP0705272A1 (de) 1996-04-10
CA2166090C (en) 2006-01-24
UA41933C2 (uk) 2001-10-15
CA2166090A1 (en) 1995-01-05
DK0705272T3 (da) 2002-05-27
AU4352693A (en) 1995-01-17
DE69331763D1 (de) 2002-05-02
FI956236A (fi) 1995-12-22
ES2173889T3 (es) 2002-11-01
KR100279567B1 (ko) 2001-03-02
PT705272E (pt) 2002-07-31
JP3253088B2 (ja) 2002-02-04
FI956236A0 (fi) 1995-12-22
AU681585B2 (en) 1997-09-04
KR960703133A (ko) 1996-06-19

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: HOESSLE PATENTANWAELTE PARTNERSCHAFT, 70173 STUTTG