DK0641759T3 - Anvendelse af aromatiske carboxylsyrederivater til fremstilling af farmaceutiske præparater - Google Patents

Anvendelse af aromatiske carboxylsyrederivater til fremstilling af farmaceutiske præparater

Info

Publication number
DK0641759T3
DK0641759T3 DK94112886T DK94112886T DK0641759T3 DK 0641759 T3 DK0641759 T3 DK 0641759T3 DK 94112886 T DK94112886 T DK 94112886T DK 94112886 T DK94112886 T DK 94112886T DK 0641759 T3 DK0641759 T3 DK 0641759T3
Authority
DK
Denmark
Prior art keywords
preparation
carboxylic acid
pharmaceutical compositions
acid derivatives
aromatic carboxylic
Prior art date
Application number
DK94112886T
Other languages
Danish (da)
English (en)
Inventor
Peter Mohr
Michael Klaus
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK0641759T3 publication Critical patent/DK0641759T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/72Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings and other rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/16Emollients or protectives, e.g. against radiation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/46Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid
    • C07C57/50Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid containing condensed ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/66Polycyclic acids with unsaturation outside the aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
    • C07C65/28Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups having unsaturation outside the aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/612Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
    • C07C69/618Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety having unsaturation outside the six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734Ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/94Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of polycyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04One of the condensed rings being a six-membered aromatic ring
    • C07C2602/12One of the condensed rings being a six-membered aromatic ring the other ring being at least seven-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Emergency Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK94112886T 1993-09-02 1994-08-18 Anvendelse af aromatiske carboxylsyrederivater til fremstilling af farmaceutiske præparater DK0641759T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH261893 1993-09-02
CH196094 1994-06-21

Publications (1)

Publication Number Publication Date
DK0641759T3 true DK0641759T3 (da) 1999-08-16

Family

ID=25689113

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94112886T DK0641759T3 (da) 1993-09-02 1994-08-18 Anvendelse af aromatiske carboxylsyrederivater til fremstilling af farmaceutiske præparater

Country Status (20)

Country Link
US (2) US5700836A (es)
EP (1) EP0641759B1 (es)
JP (1) JP2602629B2 (es)
KR (1) KR100335540B1 (es)
CN (1) CN1049423C (es)
AT (1) ATE174322T1 (es)
AU (1) AU680668B2 (es)
CA (1) CA2129773C (es)
CZ (1) CZ288426B6 (es)
DE (1) DE59407431D1 (es)
DK (1) DK0641759T3 (es)
ES (1) ES2126684T3 (es)
FI (1) FI113261B (es)
GR (1) GR3029437T3 (es)
HU (1) HU222345B1 (es)
IL (1) IL110808A (es)
NO (1) NO308579B1 (es)
NZ (1) NZ264327A (es)
RU (1) RU2130009C1 (es)
UA (1) UA43317C2 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7655699B1 (en) 1992-04-22 2010-02-02 Eisai Inc. Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors
DE4320920C1 (de) * 1993-06-24 1994-06-16 Goldschmidt Ag Th Silane mit hydrophilen Gruppen, deren Herstellung und Verwendung als Tenside in wäßrigen Medien
FR2719041B1 (fr) * 1994-04-26 1996-05-31 Cird Galderma Nouveaux composés polyéniques, compositions pharmaceutiques et cosmétiques les contenant et utilisations.
US7115728B1 (en) * 1995-01-30 2006-10-03 Ligand Pharmaceutical Incorporated Human peroxisome proliferator activated receptor γ
EP1336600A3 (en) * 1995-10-06 2004-07-07 Ligand Pharmaceuticals Incorporated Dimer-selective RXR modulators and methods for their use
US7098025B1 (en) 1997-07-25 2006-08-29 Ligand Pharmaceuticals Incorporated Human peroxisome proliferator activated receptor gamma (pparγ) gene regulatory sequences and uses therefor
JO2178B1 (en) * 1999-10-19 2003-04-23 اف . هوفمان لاروش ايه جي Treatment of invasive diseases, using selected anti-PAR materials
KR100353310B1 (ko) * 2000-03-27 2002-09-18 송웅재 축조용 돌묘
KR100385492B1 (ko) * 2000-08-10 2003-05-27 주식회사 지오지 파이프 연결 소켓 제조 방법
PL208665B1 (pl) * 2000-10-02 2011-05-31 Hoffmann La Roche Związki retinoidowe, ich zastosowanie, środek farmaceutyczny i sposób wytwarzania związków retinoidowych
EP1935869A1 (en) * 2000-10-02 2008-06-25 F. Hoffmann-La Roche Ag Retinoids for the treatment of emphysema
WO2003009807A2 (en) * 2001-07-23 2003-02-06 Galileo Laboratories, Inc. Cytoprotective compounds, pharmaceutical and cosmetic formulations, and methods
WO2005079463A2 (en) * 2004-02-17 2005-09-01 Dynamis Therapeutics, Inc. Fructoseamine 3 kinase and the formation of collagen and elastin
JP4683858B2 (ja) 2004-05-14 2011-05-18 スリーエム イノベイティブ プロパティズ カンパニー 物品支持具
WO2011028887A2 (en) 2009-09-03 2011-03-10 Becton, Dickinson And Company Methods and compositions for direct chemical lysis
EP2613776B1 (en) 2010-09-01 2020-07-29 Thomas Jefferson University Composition and method for muscle repair and regeneration
WO2012076842A1 (en) * 2010-12-09 2012-06-14 University Of Durham Synthetic retinoids for control of cell differentiation
WO2013019653A1 (en) * 2011-07-29 2013-02-07 Tempero Pharmaceuticals, Inc. Compounds and methods

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU77254A1 (es) * 1977-05-04 1979-01-18
DK159967C (da) * 1977-12-22 1991-06-03 Hoffmann La Roche Analogifremgangsmaade til fremstilling af terapeutisk aktive stilbenderivater
US4326055A (en) * 1977-12-22 1982-04-20 Hoffmann-La Roche Inc. Stilbene derivatives
DE3202100A1 (de) * 1982-01-23 1983-08-04 Basf Ag, 6700 Ludwigshafen Substituierte benzoesaeure-4-hydroxyanilide, ihre herstellung und diese enthaltende pharmazeutische zubereitungen
ZA854828B (en) * 1984-07-27 1986-03-26 Hoffmann La Roche Phenyl nonatetraenoic acid derivatives
FR2569689B1 (fr) * 1984-09-05 1990-11-16 Oreal Nouveaux derives du benzonorbornene, leurs procedes de preparation et compositions medicamenteuse et cosmetique les contenant
DE3434944A1 (de) * 1984-09-22 1986-04-03 Basf Ag, 6700 Ludwigshafen L-substituierte tetralinderivate, ihre herstellung und verwendung
US4889847A (en) * 1986-11-03 1989-12-26 Ortho Pharmaceutical Corporation Prevention of glucocorticoid-induced skin atrophy
US5019569A (en) * 1986-11-03 1991-05-28 Ortho Pharmaceutical Corporation Reversal of glucocorticoid-induced skin atrophy
CA1298309C (en) * 1987-11-06 1992-03-31 Michael Klaus Benzocycloheptene derivatives
ES2149814T3 (es) * 1992-04-22 2000-11-16 Ligand Pharm Inc Compuestos que tienen selectividad para los receptores de retinoides x.
US5324840A (en) * 1992-06-11 1994-06-28 Allergan, Inc. Method of treatment with compounds having retinoid-like activity and reduced skin toxicity and lacking teratogenic effects
DK0678087T3 (da) * 1993-01-11 1999-09-27 Ligand Pharm Inc Forbindelser med selektiv aktivitet til retinoid-X-receptorer og metoder til modulering af processer medieret af retinoid-X

Also Published As

Publication number Publication date
FI944045A (fi) 1995-03-03
GR3029437T3 (en) 1999-05-28
CN1049423C (zh) 2000-02-16
IL110808A (en) 2003-03-12
UA43317C2 (uk) 2001-12-17
IL110808A0 (en) 1994-11-11
HU222345B1 (hu) 2003-06-28
AU7148694A (en) 1995-03-16
FI944045A0 (fi) 1994-09-02
CZ210594A3 (en) 1995-06-14
CA2129773A1 (en) 1995-03-03
JPH07112952A (ja) 1995-05-02
NO943232D0 (no) 1994-09-01
ATE174322T1 (de) 1998-12-15
US6610877B1 (en) 2003-08-26
KR100335540B1 (ko) 2002-10-25
NO308579B1 (no) 2000-10-02
EP0641759B1 (de) 1998-12-09
EP0641759A1 (de) 1995-03-08
NZ264327A (en) 1996-02-27
RU94031754A (ru) 1996-07-20
NO943232L (no) 1995-03-03
CZ288426B6 (en) 2001-06-13
JP2602629B2 (ja) 1997-04-23
HU9402480D0 (en) 1994-10-28
ES2126684T3 (es) 1999-04-01
DE59407431D1 (de) 1999-01-21
FI113261B (fi) 2004-03-31
KR950008468A (ko) 1995-04-17
HUT71473A (en) 1995-11-28
CA2129773C (en) 2007-05-01
RU2130009C1 (ru) 1999-05-10
US5700836A (en) 1997-12-23
CN1105981A (zh) 1995-08-02
AU680668B2 (en) 1997-08-07

Similar Documents

Publication Publication Date Title
DK0641759T3 (da) Anvendelse af aromatiske carboxylsyrederivater til fremstilling af farmaceutiske præparater
NZ229832A (en) Condensed heterocyclic compounds, preparation and pharmaceutical compositions thereof
ATE170510T1 (de) 3-(hydroxybenzylidenyl)-indolin-2-one und diese enthaltende arzneimittel
NO924172D0 (no) Substituerte bifenylpyridoner
ATE175669T1 (de) Sulfonylaminopyrimidine, ihre herstellung und verwendung als heilmittel
NO179867C (no) Sulfonamido- og sulfonamidokarbonyl-pyridin-2-karboksylsyreamider og anvendelse av forbindelsene som legemidler
ATE157088T1 (de) Neue chinolon- und naphthyridoncarbonsäurederivate
ES2111871T3 (es) Nuevos derivados de aminoacidos, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.
AU656674B2 (en) New thiochroman compounds, processes for the preparation thereof, and pharmaceutical compositions containing them
DK0617027T3 (da) N-benzylpiperazinforbindelser, fremgangsmåde til fremstilling heraf og sammensætninger indeholdende forbindelserne
ES2062214T3 (es) Derivados de aminooligohidroxi inhibidores de renina.
ES2076054T3 (es) Nuevas amino-alquil-cromonas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen.
ES2062313T3 (es) 13-bromo- y 13,14-dibromo-ergolinas, a su preparacion y a su utilizacion en medicamentos.
DK0631777T3 (da) Anvendelse af beta-naphtoquinonderivater til hæmning af blodpladesammenklumpning
NO933465D0 (no) Legemidler inneholdende 1,5,6,7-tetrahydro -4- indazol -4- on-derivater, nye 1,5,6,7 - tetrahydro -4- indazol -4- on-derivater, og fremgangsmaate for deres fremstilling
DK0518769T3 (da) Hidtil ukendte ethanolaminbenzoatderivater, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder dem.
ES2123038T3 (es) Nuevos derivados pirrolo-tieno-pirazinicos, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.