ES2126684T3 - Utilizacion de derivados de acidos carboxilicos aromaticos para la preparacion de medicamentos. - Google Patents
Utilizacion de derivados de acidos carboxilicos aromaticos para la preparacion de medicamentos.Info
- Publication number
- ES2126684T3 ES2126684T3 ES94112886T ES94112886T ES2126684T3 ES 2126684 T3 ES2126684 T3 ES 2126684T3 ES 94112886 T ES94112886 T ES 94112886T ES 94112886 T ES94112886 T ES 94112886T ES 2126684 T3 ES2126684 T3 ES 2126684T3
- Authority
- ES
- Spain
- Prior art keywords
- medicines
- preparation
- acid derivatives
- carboxyl acid
- aromatic carboxyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/72—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings and other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/46—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid
- C07C57/50—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid containing condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
- C07C63/66—Polycyclic acids with unsaturation outside the aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
- C07C65/28—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups having unsaturation outside the aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/612—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
- C07C69/618—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety having unsaturation outside the six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/734—Ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
- C07C69/94—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of polycyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/12—One of the condensed rings being a six-membered aromatic ring the other ring being at least seven-membered
Abstract
LOS COMPUESTOS DE LA FORMULA DONDE R1 ES UN RESTO DE LAS FORMULAS Y R2 IPCION, PUEDEN SER UTILIZADOS COMO MEDICAMENTOS, ESPECIALMENTE PARA INDICACIONES DERMATOLOGICAS Y ONCOLOGICAS.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH261893 | 1993-09-02 | ||
CH196094 | 1994-06-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2126684T3 true ES2126684T3 (es) | 1999-04-01 |
Family
ID=25689113
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94112886T Expired - Lifetime ES2126684T3 (es) | 1993-09-02 | 1994-08-18 | Utilizacion de derivados de acidos carboxilicos aromaticos para la preparacion de medicamentos. |
Country Status (20)
Country | Link |
---|---|
US (2) | US5700836A (es) |
EP (1) | EP0641759B1 (es) |
JP (1) | JP2602629B2 (es) |
KR (1) | KR100335540B1 (es) |
CN (1) | CN1049423C (es) |
AT (1) | ATE174322T1 (es) |
AU (1) | AU680668B2 (es) |
CA (1) | CA2129773C (es) |
CZ (1) | CZ288426B6 (es) |
DE (1) | DE59407431D1 (es) |
DK (1) | DK0641759T3 (es) |
ES (1) | ES2126684T3 (es) |
FI (1) | FI113261B (es) |
GR (1) | GR3029437T3 (es) |
HU (1) | HU222345B1 (es) |
IL (1) | IL110808A (es) |
NO (1) | NO308579B1 (es) |
NZ (1) | NZ264327A (es) |
RU (1) | RU2130009C1 (es) |
UA (1) | UA43317C2 (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7655699B1 (en) | 1992-04-22 | 2010-02-02 | Eisai Inc. | Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors |
DE4320920C1 (de) * | 1993-06-24 | 1994-06-16 | Goldschmidt Ag Th | Silane mit hydrophilen Gruppen, deren Herstellung und Verwendung als Tenside in wäßrigen Medien |
FR2719041B1 (fr) * | 1994-04-26 | 1996-05-31 | Cird Galderma | Nouveaux composés polyéniques, compositions pharmaceutiques et cosmétiques les contenant et utilisations. |
US7115728B1 (en) * | 1995-01-30 | 2006-10-03 | Ligand Pharmaceutical Incorporated | Human peroxisome proliferator activated receptor γ |
KR100625255B1 (ko) * | 1995-10-06 | 2008-01-30 | 리간드 파마슈티칼스 인코포레이티드 | 다이머-선택적rxr변조물질및그의사용방법 |
AU8588798A (en) | 1997-07-25 | 1999-02-16 | Institut Pasteur | Human peroxisome proliferator activated receptor gamma (ppargamma) gene re gulatory sequences and uses therefor |
JO2178B1 (en) * | 1999-10-19 | 2003-04-23 | اف . هوفمان لاروش ايه جي | Treatment of invasive diseases, using selected anti-PAR materials |
KR100353310B1 (ko) * | 2000-03-27 | 2002-09-18 | 송웅재 | 축조용 돌묘 |
KR100385492B1 (ko) * | 2000-08-10 | 2003-05-27 | 주식회사 지오지 | 파이프 연결 소켓 제조 방법 |
ATE413375T1 (de) * | 2000-10-02 | 2008-11-15 | Hoffmann La Roche | Retinoide zur behandlung von emphysem |
EP1935869A1 (en) * | 2000-10-02 | 2008-06-25 | F. Hoffmann-La Roche Ag | Retinoids for the treatment of emphysema |
JP4425628B2 (ja) * | 2001-07-23 | 2010-03-03 | ジョンソン・アンド・ジョンソン・コンシューマー・カンパニーズ・インコーポレイテッド | 細胞保護化合物、薬学的処方物および美容用処方物、ならびに方法 |
WO2005079463A2 (en) * | 2004-02-17 | 2005-09-01 | Dynamis Therapeutics, Inc. | Fructoseamine 3 kinase and the formation of collagen and elastin |
JP4683858B2 (ja) | 2004-05-14 | 2011-05-18 | スリーエム イノベイティブ プロパティズ カンパニー | 物品支持具 |
EP2473596B1 (en) | 2009-09-03 | 2017-12-13 | Becton, Dickinson and Company | Methods and compositions for direct chemical lysis |
EP2613776B1 (en) | 2010-09-01 | 2020-07-29 | Thomas Jefferson University | Composition and method for muscle repair and regeneration |
WO2012076842A1 (en) * | 2010-12-09 | 2012-06-14 | University Of Durham | Synthetic retinoids for control of cell differentiation |
EP2736332A4 (en) * | 2011-07-29 | 2015-03-18 | Tempero Pharmaceuticals Inc | CONNECTIONS AND METHODS |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
LU77254A1 (es) * | 1977-05-04 | 1979-01-18 | ||
DK159967C (da) * | 1977-12-22 | 1991-06-03 | Hoffmann La Roche | Analogifremgangsmaade til fremstilling af terapeutisk aktive stilbenderivater |
US4326055A (en) * | 1977-12-22 | 1982-04-20 | Hoffmann-La Roche Inc. | Stilbene derivatives |
DE3202100A1 (de) * | 1982-01-23 | 1983-08-04 | Basf Ag, 6700 Ludwigshafen | Substituierte benzoesaeure-4-hydroxyanilide, ihre herstellung und diese enthaltende pharmazeutische zubereitungen |
ZA854828B (en) * | 1984-07-27 | 1986-03-26 | Hoffmann La Roche | Phenyl nonatetraenoic acid derivatives |
US4783549A (en) * | 1984-09-05 | 1988-11-08 | L'oreal | Benzonorbornene derivatives, processes for their preparation and medicinal and cosmetic compositions containing them |
DE3434944A1 (de) * | 1984-09-22 | 1986-04-03 | Basf Ag, 6700 Ludwigshafen | L-substituierte tetralinderivate, ihre herstellung und verwendung |
US4889847A (en) * | 1986-11-03 | 1989-12-26 | Ortho Pharmaceutical Corporation | Prevention of glucocorticoid-induced skin atrophy |
US5019569A (en) * | 1986-11-03 | 1991-05-28 | Ortho Pharmaceutical Corporation | Reversal of glucocorticoid-induced skin atrophy |
CA1298309C (en) * | 1987-11-06 | 1992-03-31 | Michael Klaus | Benzocycloheptene derivatives |
ATE307795T1 (de) * | 1992-04-22 | 2005-11-15 | Ligand Pharm Inc | Verbindungen mit retinoid x rezeptorselektivität |
US5324840A (en) * | 1992-06-11 | 1994-06-28 | Allergan, Inc. | Method of treatment with compounds having retinoid-like activity and reduced skin toxicity and lacking teratogenic effects |
WO1995004036A1 (en) * | 1993-01-11 | 1995-02-09 | Ligand Pharmaceuticals Inc. | Compounds having selective activity for retinoid x receptors, and means for modulation of processes mediated by retinoid x receptors |
-
1994
- 1994-08-09 CA CA002129773A patent/CA2129773C/en not_active Expired - Fee Related
- 1994-08-18 DK DK94112886T patent/DK0641759T3/da active
- 1994-08-18 DE DE59407431T patent/DE59407431D1/de not_active Expired - Fee Related
- 1994-08-18 AT AT94112886T patent/ATE174322T1/de not_active IP Right Cessation
- 1994-08-18 ES ES94112886T patent/ES2126684T3/es not_active Expired - Lifetime
- 1994-08-18 EP EP94112886A patent/EP0641759B1/de not_active Expired - Lifetime
- 1994-08-25 AU AU71486/94A patent/AU680668B2/en not_active Ceased
- 1994-08-29 NZ NZ264327A patent/NZ264327A/en unknown
- 1994-08-29 HU HU9402480A patent/HU222345B1/hu not_active IP Right Cessation
- 1994-08-29 IL IL11080894A patent/IL110808A/xx not_active IP Right Cessation
- 1994-08-29 JP JP6203653A patent/JP2602629B2/ja not_active Expired - Fee Related
- 1994-09-01 UA UA94095764A patent/UA43317C2/uk unknown
- 1994-09-01 CZ CZ19942105A patent/CZ288426B6/cs not_active IP Right Cessation
- 1994-09-01 KR KR1019940021952A patent/KR100335540B1/ko not_active IP Right Cessation
- 1994-09-01 RU RU94031754A patent/RU2130009C1/ru not_active IP Right Cessation
- 1994-09-01 NO NO943232A patent/NO308579B1/no unknown
- 1994-09-01 CN CN94115650A patent/CN1049423C/zh not_active Expired - Fee Related
- 1994-09-02 FI FI944045A patent/FI113261B/fi active
-
1996
- 1996-10-21 US US08/734,222 patent/US5700836A/en not_active Expired - Fee Related
-
1997
- 1997-08-01 US US08/904,522 patent/US6610877B1/en not_active Expired - Fee Related
-
1999
- 1999-02-17 GR GR990400520T patent/GR3029437T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
HU222345B1 (hu) | 2003-06-28 |
NO308579B1 (no) | 2000-10-02 |
KR100335540B1 (ko) | 2002-10-25 |
US6610877B1 (en) | 2003-08-26 |
ATE174322T1 (de) | 1998-12-15 |
RU2130009C1 (ru) | 1999-05-10 |
KR950008468A (ko) | 1995-04-17 |
EP0641759B1 (de) | 1998-12-09 |
IL110808A0 (en) | 1994-11-11 |
DE59407431D1 (de) | 1999-01-21 |
NO943232L (no) | 1995-03-03 |
CZ288426B6 (en) | 2001-06-13 |
JPH07112952A (ja) | 1995-05-02 |
CA2129773A1 (en) | 1995-03-03 |
FI113261B (fi) | 2004-03-31 |
JP2602629B2 (ja) | 1997-04-23 |
GR3029437T3 (en) | 1999-05-28 |
RU94031754A (ru) | 1996-07-20 |
CN1049423C (zh) | 2000-02-16 |
NO943232D0 (no) | 1994-09-01 |
DK0641759T3 (da) | 1999-08-16 |
CZ210594A3 (en) | 1995-06-14 |
IL110808A (en) | 2003-03-12 |
AU680668B2 (en) | 1997-08-07 |
US5700836A (en) | 1997-12-23 |
HU9402480D0 (en) | 1994-10-28 |
NZ264327A (en) | 1996-02-27 |
FI944045A0 (fi) | 1994-09-02 |
FI944045A (fi) | 1995-03-03 |
AU7148694A (en) | 1995-03-16 |
EP0641759A1 (de) | 1995-03-08 |
CN1105981A (zh) | 1995-08-02 |
CA2129773C (en) | 2007-05-01 |
HUT71473A (en) | 1995-11-28 |
UA43317C2 (uk) | 2001-12-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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