DK0625069T3 - Fremgangsmåde til fremstilling af mikrokapsler - Google Patents

Fremgangsmåde til fremstilling af mikrokapsler

Info

Publication number
DK0625069T3
DK0625069T3 DK93922486T DK93922486T DK0625069T3 DK 0625069 T3 DK0625069 T3 DK 0625069T3 DK 93922486 T DK93922486 T DK 93922486T DK 93922486 T DK93922486 T DK 93922486T DK 0625069 T3 DK0625069 T3 DK 0625069T3
Authority
DK
Denmark
Prior art keywords
microcapsules
making microcapsules
solvents
biodegradable
vaccines
Prior art date
Application number
DK93922486T
Other languages
Danish (da)
English (en)
Inventor
Bruno Gander
Hans Peter Merkle
Original Assignee
Sanol Arznei Schwarz Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanol Arznei Schwarz Gmbh filed Critical Sanol Arznei Schwarz Gmbh
Application granted granted Critical
Publication of DK0625069T3 publication Critical patent/DK0625069T3/da

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02Making microcapsules or microballoons
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02Making microcapsules or microballoons
    • B01J13/04Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • B01J13/043Drying and spraying
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089Processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02Making microcapsules or microballoons
    • B01J13/06Making microcapsules or microballoons by phase separation
    • B01J13/12Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution
DK93922486T 1992-10-26 1993-10-18 Fremgangsmåde til fremstilling af mikrokapsler DK0625069T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH331992 1992-10-26
PCT/CH1993/000246 WO1994009898A1 (de) 1992-10-26 1993-10-18 Verfahren zur herstellung von mikrokapseln

Publications (1)

Publication Number Publication Date
DK0625069T3 true DK0625069T3 (da) 1999-08-30

Family

ID=4253421

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93922486T DK0625069T3 (da) 1992-10-26 1993-10-18 Fremgangsmåde til fremstilling af mikrokapsler

Country Status (14)

Country Link
US (1) US5648096A (fi)
EP (1) EP0625069B1 (fi)
JP (1) JP3523254B2 (fi)
KR (1) KR100225983B1 (fi)
CN (1) CN1058864C (fi)
AT (1) ATE175132T1 (fi)
CA (1) CA2126685C (fi)
DE (1) DE59309257D1 (fi)
DK (1) DK0625069T3 (fi)
ES (1) ES2127835T3 (fi)
FI (1) FI943067A (fi)
GR (1) GR3029504T3 (fi)
HU (1) HU221308B1 (fi)
WO (1) WO1994009898A1 (fi)

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Also Published As

Publication number Publication date
GR3029504T3 (en) 1999-05-28
CA2126685C (en) 2002-07-23
KR940703713A (ko) 1994-12-12
HU221308B1 (en) 2002-09-28
ES2127835T3 (es) 1999-05-01
US5648096A (en) 1997-07-15
WO1994009898A1 (de) 1994-05-11
EP0625069A1 (de) 1994-11-23
CN1090172A (zh) 1994-08-03
HUT70418A (en) 1995-10-30
CA2126685A1 (en) 1994-05-11
JPH07502686A (ja) 1995-03-23
HU9401329D0 (en) 1994-08-29
FI943067A0 (fi) 1994-06-23
FI943067A (fi) 1994-06-23
DE59309257D1 (de) 1999-02-11
JP3523254B2 (ja) 2004-04-26
ATE175132T1 (de) 1999-01-15
KR100225983B1 (ko) 1999-10-15
EP0625069B1 (de) 1998-12-30
CN1058864C (zh) 2000-11-29

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