DK0595868T3 - Fremgangsmåde til fremstilling af (S)-4-[3-(5-methyl-2-phenyl-4-oxazolyl)-1-hydroxypropyl]-brombenzen - Google Patents
Fremgangsmåde til fremstilling af (S)-4-[3-(5-methyl-2-phenyl-4-oxazolyl)-1-hydroxypropyl]-brombenzenInfo
- Publication number
- DK0595868T3 DK0595868T3 DK92915192T DK92915192T DK0595868T3 DK 0595868 T3 DK0595868 T3 DK 0595868T3 DK 92915192 T DK92915192 T DK 92915192T DK 92915192 T DK92915192 T DK 92915192T DK 0595868 T3 DK0595868 T3 DK 0595868T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- bromobenzene
- oxazolyl
- hydroxypropyl
- phenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73356491A | 1991-07-22 | 1991-07-22 | |
| PCT/US1992/005433 WO1993002060A1 (fr) | 1991-07-22 | 1992-07-01 | Procede de preparation d'intermediaires dans la synthese de derives chiraux de thiazolidine-2,4-dione |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0595868T3 true DK0595868T3 (da) | 1999-08-09 |
Family
ID=24948157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK92915192T DK0595868T3 (da) | 1991-07-22 | 1992-07-01 | Fremgangsmåde til fremstilling af (S)-4-[3-(5-methyl-2-phenyl-4-oxazolyl)-1-hydroxypropyl]-brombenzen |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US5512689A (fr) |
| EP (1) | EP0595868B1 (fr) |
| JP (1) | JP2671962B2 (fr) |
| AT (1) | ATE173728T1 (fr) |
| AU (1) | AU660701B2 (fr) |
| CA (1) | CA2111445C (fr) |
| DE (1) | DE69227689T2 (fr) |
| DK (1) | DK0595868T3 (fr) |
| ES (1) | ES2123562T3 (fr) |
| FI (1) | FI940306A0 (fr) |
| HU (1) | HUT70412A (fr) |
| IE (1) | IE922359A1 (fr) |
| IL (1) | IL102574A (fr) |
| MX (1) | MX9204278A (fr) |
| MY (1) | MY131277A (fr) |
| NO (1) | NO940227L (fr) |
| NZ (1) | NZ243651A (fr) |
| PT (1) | PT100710B (fr) |
| TW (1) | TW199891B (fr) |
| WO (1) | WO1993002060A1 (fr) |
| ZA (1) | ZA925469B (fr) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2111446C (fr) * | 1991-07-22 | 1997-12-16 | George J. Quallich | Intermediaires chiraux servant a l'obtention de thiazoles antidiabetiques |
| FR2699172B1 (fr) * | 1992-12-11 | 1995-01-20 | Adir | Nouveaux dérivés de 4-méthyl-1,3-oxazole, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
| TW416958B (en) * | 1993-05-14 | 2001-01-01 | Pfizer | Enantioselective oxazaborolidine catalysts |
| EA200200311A1 (ru) * | 1999-08-31 | 2002-08-29 | Максиа Фармасьютикалз, Инк. | Бензилиден-тиазолидиндионы и аналоги и их применение для лечения диабета |
| AU2002252227A1 (en) | 2001-03-07 | 2002-09-24 | Maxia Pharmaceuticals, Inc. | Heterocyclic derivatives for the treatment of cancer and other proliferative diseases |
| JP2004523571A (ja) * | 2001-03-08 | 2004-08-05 | マキシア・ファーマシューティカルズ・インコーポレイテッド | Ｒｘｒ活性化分子 |
| CA2340824A1 (fr) * | 2001-03-14 | 2002-09-14 | Ibm Canada Limited-Ibm Canada Limitee | Methode et systeme pour l'analyse du comportement des applications |
| US20030083357A1 (en) * | 2001-08-17 | 2003-05-01 | Magnus Pfahl | Oxime derivatives for the treatment of dyslipidemia and hypercholesteremia |
| AU2002352706A1 (en) * | 2001-11-15 | 2003-06-10 | Maxia Pharmaceuticals, Inc. | N-substituted heterocycles for the treatment of hypercholesteremia, dyslipidemia and other metabolic disorders, cancer, and other diseases |
| US7102000B2 (en) * | 2002-03-08 | 2006-09-05 | Incyte San Diego Inc. | Heterocyclic amide derivatives for the treatment of diabetes and other diseases |
| US7196108B2 (en) * | 2002-03-08 | 2007-03-27 | Incyte San Diego Inc. | Bicyclic heterocycles for the treatment of diabetes and other diseases |
| US20050014767A1 (en) * | 2003-01-29 | 2005-01-20 | Magnus Pfahl | Benzoxazole, benzothiazole, and benzimidazole derivatives for the treatment of cancer and other diseases |
| JP2006523724A (ja) * | 2003-04-18 | 2006-10-19 | インサイト サン ディエゴ インコーポレイテッド | 代謝障害、癌および他の疾患の治療のための置換イソクロマン化合物 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4943635A (en) * | 1987-08-27 | 1990-07-24 | President & Fellows Of Harvard College | Enantioselective reduction of ketones |
| US5036079A (en) * | 1989-12-07 | 1991-07-30 | Pfizer Inc. | Hypoglycemic thiazolidinedione derivatives |
| TW222626B (fr) * | 1991-07-22 | 1994-04-21 | Pfizer |
-
1992
- 1992-07-01 DK DK92915192T patent/DK0595868T3/da active
- 1992-07-01 EP EP92915192A patent/EP0595868B1/fr not_active Expired - Lifetime
- 1992-07-01 HU HU9400188A patent/HUT70412A/hu unknown
- 1992-07-01 JP JP5502810A patent/JP2671962B2/ja not_active Expired - Fee Related
- 1992-07-01 WO PCT/US1992/005433 patent/WO1993002060A1/fr active IP Right Grant
- 1992-07-01 AU AU23062/92A patent/AU660701B2/en not_active Ceased
- 1992-07-01 AT AT92915192T patent/ATE173728T1/de not_active IP Right Cessation
- 1992-07-01 CA CA002111445A patent/CA2111445C/fr not_active Expired - Fee Related
- 1992-07-01 ES ES92915192T patent/ES2123562T3/es not_active Expired - Lifetime
- 1992-07-01 DE DE69227689T patent/DE69227689T2/de not_active Expired - Fee Related
- 1992-07-07 TW TW081105396A patent/TW199891B/zh active
- 1992-07-20 PT PT100710A patent/PT100710B/pt not_active IP Right Cessation
- 1992-07-21 ZA ZA925469A patent/ZA925469B/xx unknown
- 1992-07-21 IL IL10257492A patent/IL102574A/en not_active IP Right Cessation
- 1992-07-21 IE IE235992A patent/IE922359A1/en not_active IP Right Cessation
- 1992-07-21 MX MX9204278A patent/MX9204278A/es unknown
- 1992-07-21 NZ NZ243651A patent/NZ243651A/en unknown
- 1992-07-21 MY MYPI92001294A patent/MY131277A/en unknown
-
1994
- 1994-01-21 NO NO940227A patent/NO940227L/no unknown
- 1994-01-21 FI FI940306A patent/FI940306A0/fi unknown
-
1995
- 1995-04-05 US US08/417,502 patent/US5512689A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2111445C (fr) | 1997-02-18 |
| IL102574A0 (en) | 1993-01-14 |
| MX9204278A (es) | 1994-03-31 |
| FI940306A (fi) | 1994-01-21 |
| AU660701B2 (en) | 1995-07-06 |
| ES2123562T3 (es) | 1999-01-16 |
| NZ243651A (en) | 1994-01-26 |
| PT100710B (pt) | 1999-07-30 |
| ATE173728T1 (de) | 1998-12-15 |
| JPH07502017A (ja) | 1995-03-02 |
| IE922359A1 (en) | 1993-01-27 |
| DE69227689T2 (de) | 1999-04-22 |
| HUT70412A (en) | 1995-10-30 |
| PT100710A (pt) | 1993-09-30 |
| MY131277A (en) | 2007-07-31 |
| US5512689A (en) | 1996-04-30 |
| JP2671962B2 (ja) | 1997-11-05 |
| CA2111445A1 (fr) | 1993-02-04 |
| HU9400188D0 (en) | 1994-05-30 |
| EP0595868B1 (fr) | 1998-11-25 |
| AU2306292A (en) | 1993-02-23 |
| WO1993002060A1 (fr) | 1993-02-04 |
| FI940306A0 (fi) | 1994-01-21 |
| DE69227689D1 (de) | 1999-01-07 |
| ZA925469B (en) | 1994-01-21 |
| NO940227D0 (no) | 1994-01-21 |
| TW199891B (fr) | 1993-02-11 |
| NO940227L (no) | 1994-01-21 |
| IL102574A (en) | 1996-07-23 |
| EP0595868A1 (fr) | 1994-05-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK0595868T3 (da) | Fremgangsmåde til fremstilling af (S)-4-[3-(5-methyl-2-phenyl-4-oxazolyl)-1-hydroxypropyl]-brombenzen | |
| FI94756C (fi) | Menetelmä hypoglykeemisten ja hypokolesteroleemisten oksa- ja tiatsolidiinidionien valmistamiseksi | |
| GB2128987B (en) | Intermediates for hypoglycemic 5-substituted oxazolidine-2,4-diones | |
| AU7343581A (en) | Hypoglycemic 5-substituted oxazolidine-2,4-diones | |
| SE8600174D0 (sv) | Nytt forfarande for framstellning av n-(2-pyrimidinyl)-piperazinylalkylazaspiroalkandioner | |
| NO992226D0 (no) | Nye forbindelser for anvendelse som neuro-protektive midler | |
| IE790364L (en) | 2-nitro aminopyrimidone derivatives | |
| AU548932B2 (en) | Intermediates for 5-substituted oxazolidine-2,4-diones | |
| FR2464131B1 (fr) | Machine a mouler sous pression, en particulier pour elements moules en ceramique | |
| HUP9903765A2 (hu) | Eljárás 3-(1-piperazinil)-1,2-benzizotiazol előállítására, valamint ennek közbenső termékei | |
| DK0693055T3 (da) | Hidtil ukendt fremgangsmåde til fremstilling af clonidinderivater | |
| SE8104541L (sv) | Sett att framstella 5-substituerade dialursyror | |
| DK0500177T3 (da) | Fremgangsmåde til fremstilling af trans-(5R)-2,4,5-trisubstituerede 2-oxazoliner | |
| DK0649849T3 (da) | Fremgangsmåde til fremstilling af cephalosporiner | |
| DK0761657T3 (da) | Fremgangsmåde til fremstilling af benzylsubstituerede rhodaninderivater | |
| DK0496846T3 (da) | Fremgangsmåde til fremstilling af 17-oxosteroider | |
| KR850003307A (ko) | 5-치환된 옥사졸리딘-2, 4-디온의 제조방법 | |
| YU92183A (en) | Process for obtaining hypoglycemic 5-substituted oxazolidine-2,4-diones | |
| AU529943B2 (en) | 5-(2-((3-(1,3-benzodioxol-5-yl)-1-methylpropyl)amino)-1- hydroxyethyl)-2-methoxybenzamide | |
| IE842427L (en) | Intermediates for hypoglycemic oxazolidine-2, 4-diones |