ZA925469B - Process for chiral thiazolidine-2,4-dione hypoglycemics and intermediates - Google Patents

Process for chiral thiazolidine-2,4-dione hypoglycemics and intermediates

Info

Publication number
ZA925469B
ZA925469B ZA925469A ZA925469A ZA925469B ZA 925469 B ZA925469 B ZA 925469B ZA 925469 A ZA925469 A ZA 925469A ZA 925469 A ZA925469 A ZA 925469A ZA 925469 B ZA925469 B ZA 925469B
Authority
ZA
South Africa
Prior art keywords
hypoglycemics
dione
intermediates
thiazolidine
chiral
Prior art date
Application number
ZA925469A
Other languages
English (en)
Inventor
George J Quallich
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA925469B publication Critical patent/ZA925469B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA925469A 1991-07-22 1992-07-21 Process for chiral thiazolidine-2,4-dione hypoglycemics and intermediates ZA925469B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73356491A 1991-07-22 1991-07-22

Publications (1)

Publication Number Publication Date
ZA925469B true ZA925469B (en) 1994-01-21

Family

ID=24948157

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA925469A ZA925469B (en) 1991-07-22 1992-07-21 Process for chiral thiazolidine-2,4-dione hypoglycemics and intermediates

Country Status (21)

Country Link
US (1) US5512689A (fr)
EP (1) EP0595868B1 (fr)
JP (1) JP2671962B2 (fr)
AT (1) ATE173728T1 (fr)
AU (1) AU660701B2 (fr)
CA (1) CA2111445C (fr)
DE (1) DE69227689T2 (fr)
DK (1) DK0595868T3 (fr)
ES (1) ES2123562T3 (fr)
FI (1) FI940306A0 (fr)
HU (1) HUT70412A (fr)
IE (1) IE922359A1 (fr)
IL (1) IL102574A (fr)
MX (1) MX9204278A (fr)
MY (1) MY131277A (fr)
NO (1) NO940227D0 (fr)
NZ (1) NZ243651A (fr)
PT (1) PT100710B (fr)
TW (1) TW199891B (fr)
WO (1) WO1993002060A1 (fr)
ZA (1) ZA925469B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT70422A (en) * 1991-07-22 1995-10-30 Pfizer Chiral thiazole derivatives and process for preparing them
FR2699172B1 (fr) * 1992-12-11 1995-01-20 Adir Nouveaux dérivés de 4-méthyl-1,3-oxazole, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
TW416958B (en) * 1993-05-14 2001-01-01 Pfizer Enantioselective oxazaborolidine catalysts
ES2248107T3 (es) 1999-08-31 2006-03-16 Incyte San Diego Incorporated Benciliden-tiazolidindionas y analogos y su utilizacion en el tratamiento de la diabetes.
AU2002252227A1 (en) 2001-03-07 2002-09-24 Maxia Pharmaceuticals, Inc. Heterocyclic derivatives for the treatment of cancer and other proliferative diseases
CA2473156A1 (fr) * 2001-03-08 2002-09-19 Incyte San Diego, Inc. Molecules activant un recepteur rxr
CA2340824A1 (fr) * 2001-03-14 2002-09-14 Ibm Canada Limited-Ibm Canada Limitee Methode et systeme pour l'analyse du comportement des applications
EP1421061A4 (fr) * 2001-08-17 2004-12-22 Incyte San Diego Inc Derives d'oxime pour le traitement de la dyslipidemie et de l'hypercholesterolemie
JP2005513026A (ja) * 2001-11-15 2005-05-12 インサイト サン ディエゴ インコーポレイテッド 高コレステロール血症、異脂肪血症および他の代謝障害；癌、および他の疾患を治療するｎ−置換複素環
US7196108B2 (en) * 2002-03-08 2007-03-27 Incyte San Diego Inc. Bicyclic heterocycles for the treatment of diabetes and other diseases
US7102000B2 (en) * 2002-03-08 2006-09-05 Incyte San Diego Inc. Heterocyclic amide derivatives for the treatment of diabetes and other diseases
US20050014767A1 (en) * 2003-01-29 2005-01-20 Magnus Pfahl Benzoxazole, benzothiazole, and benzimidazole derivatives for the treatment of cancer and other diseases
MXPA05011242A (es) * 2003-04-18 2006-07-06 Incyte San Diego Inc Compuestos isocromanos sustituidos para el tratamiento de trastornos metabolicos, cancer y otras enfermedades.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4943635A (en) * 1987-08-27 1990-07-24 President & Fellows Of Harvard College Enantioselective reduction of ketones
US5036079A (en) * 1989-12-07 1991-07-30 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
TW222626B (fr) * 1991-07-22 1994-04-21 Pfizer

Also Published As

Publication number Publication date
TW199891B (fr) 1993-02-11
WO1993002060A1 (fr) 1993-02-04
AU660701B2 (en) 1995-07-06
IL102574A0 (en) 1993-01-14
HUT70412A (en) 1995-10-30
EP0595868B1 (fr) 1998-11-25
NO940227L (no) 1994-01-21
EP0595868A1 (fr) 1994-05-11
HU9400188D0 (en) 1994-05-30
US5512689A (en) 1996-04-30
DE69227689T2 (de) 1999-04-22
IL102574A (en) 1996-07-23
JP2671962B2 (ja) 1997-11-05
IE922359A1 (en) 1993-01-27
NZ243651A (en) 1994-01-26
DK0595868T3 (da) 1999-08-09
CA2111445A1 (fr) 1993-02-04
FI940306A (fi) 1994-01-21
PT100710A (pt) 1993-09-30
MY131277A (en) 2007-07-31
ES2123562T3 (es) 1999-01-16
JPH07502017A (ja) 1995-03-02
AU2306292A (en) 1993-02-23
DE69227689D1 (de) 1999-01-07
MX9204278A (es) 1994-03-31
FI940306A0 (fi) 1994-01-21
CA2111445C (fr) 1997-02-18
ATE173728T1 (de) 1998-12-15
PT100710B (pt) 1999-07-30
NO940227D0 (no) 1994-01-21

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