DE69227689D1 - Verfahren zur herstellung von (s)-4-[3-(5-methyl-2-phenyl-4-oxazolyl)- 1-hydroxypropyl] brombenzol - Google Patents
Verfahren zur herstellung von (s)-4-[3-(5-methyl-2-phenyl-4-oxazolyl)- 1-hydroxypropyl] brombenzolInfo
- Publication number
- DE69227689D1 DE69227689D1 DE69227689T DE69227689T DE69227689D1 DE 69227689 D1 DE69227689 D1 DE 69227689D1 DE 69227689 T DE69227689 T DE 69227689T DE 69227689 T DE69227689 T DE 69227689T DE 69227689 D1 DE69227689 D1 DE 69227689D1
- Authority
- DE
- Germany
- Prior art keywords
- brombenzol
- oxazolyl
- hydroxypropyl
- phenyl
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73356491A | 1991-07-22 | 1991-07-22 | |
| PCT/US1992/005433 WO1993002060A1 (en) | 1991-07-22 | 1992-07-01 | Process for the preparation of intermediates in the synthesis of chiral thiazolidine-2,4-dione derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69227689D1 true DE69227689D1 (de) | 1999-01-07 |
| DE69227689T2 DE69227689T2 (de) | 1999-04-22 |
Family
ID=24948157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69227689T Expired - Fee Related DE69227689T2 (de) | 1991-07-22 | 1992-07-01 | Verfahren zur herstellung von (s)-4-[3-(5-methyl-2-phenyl-4-oxazolyl)- 1-hydroxypropyl] brombenzol |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US5512689A (de) |
| EP (1) | EP0595868B1 (de) |
| JP (1) | JP2671962B2 (de) |
| AT (1) | ATE173728T1 (de) |
| AU (1) | AU660701B2 (de) |
| CA (1) | CA2111445C (de) |
| DE (1) | DE69227689T2 (de) |
| DK (1) | DK0595868T3 (de) |
| ES (1) | ES2123562T3 (de) |
| FI (1) | FI940306A0 (de) |
| HU (1) | HUT70412A (de) |
| IE (1) | IE922359A1 (de) |
| IL (1) | IL102574A (de) |
| MX (1) | MX9204278A (de) |
| MY (1) | MY131277A (de) |
| NO (1) | NO940227L (de) |
| NZ (1) | NZ243651A (de) |
| PT (1) | PT100710B (de) |
| TW (1) | TW199891B (de) |
| WO (1) | WO1993002060A1 (de) |
| ZA (1) | ZA925469B (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU660187B2 (en) * | 1991-07-22 | 1995-06-15 | Pfizer Inc. | Chiral intermediates for the preparation of antidiabetics thiazoles |
| FR2699172B1 (fr) * | 1992-12-11 | 1995-01-20 | Adir | Nouveaux dérivés de 4-méthyl-1,3-oxazole, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
| TW416958B (en) * | 1993-05-14 | 2001-01-01 | Pfizer | Enantioselective oxazaborolidine catalysts |
| CA2383347A1 (en) * | 1999-08-31 | 2001-03-08 | Maxia Pharmaceuticals, Inc. | Benzylidene-thiazolidinediones and analogues and their use in the treatment of diabetes |
| IL157740A0 (en) | 2001-03-07 | 2004-03-28 | Incyte San Diego Inc | Heterocyclic derivatives and pharmaceutical compositions containing the same |
| US7265139B2 (en) * | 2001-03-08 | 2007-09-04 | Incyte San Diego Inc. | RXR activating molecules |
| CA2340824A1 (en) * | 2001-03-14 | 2002-09-14 | Ibm Canada Limited-Ibm Canada Limitee | Method and system for application behavior analysis |
| EP1421061A4 (de) * | 2001-08-17 | 2004-12-22 | Incyte San Diego Inc | Oximderivate für die behandlung von dyslipidämie und hypercholesterinämie |
| AU2002352706A1 (en) * | 2001-11-15 | 2003-06-10 | Maxia Pharmaceuticals, Inc. | N-substituted heterocycles for the treatment of hypercholesteremia, dyslipidemia and other metabolic disorders, cancer, and other diseases |
| US7196108B2 (en) * | 2002-03-08 | 2007-03-27 | Incyte San Diego Inc. | Bicyclic heterocycles for the treatment of diabetes and other diseases |
| US7102000B2 (en) * | 2002-03-08 | 2006-09-05 | Incyte San Diego Inc. | Heterocyclic amide derivatives for the treatment of diabetes and other diseases |
| WO2004066952A2 (en) * | 2003-01-29 | 2004-08-12 | Incyte Corporation | Benzoxazole, benzothiazole, and benzimidazole derivatives for the treatment of cancer and other diseases |
| EP1643993A2 (de) * | 2003-04-18 | 2006-04-12 | Incyte San Diego Incorporated | Substituiert isochroman-verbindungen zur behandlung von stoffwechselerkrankungen, krebs und anderen erkrankungen |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4943635A (en) * | 1987-08-27 | 1990-07-24 | President & Fellows Of Harvard College | Enantioselective reduction of ketones |
| US5036079A (en) * | 1989-12-07 | 1991-07-30 | Pfizer Inc. | Hypoglycemic thiazolidinedione derivatives |
| TW222626B (de) * | 1991-07-22 | 1994-04-21 | Pfizer |
-
1992
- 1992-07-01 DE DE69227689T patent/DE69227689T2/de not_active Expired - Fee Related
- 1992-07-01 JP JP5502810A patent/JP2671962B2/ja not_active Expired - Fee Related
- 1992-07-01 EP EP92915192A patent/EP0595868B1/de not_active Expired - Lifetime
- 1992-07-01 CA CA002111445A patent/CA2111445C/en not_active Expired - Fee Related
- 1992-07-01 HU HU9400188A patent/HUT70412A/hu unknown
- 1992-07-01 DK DK92915192T patent/DK0595868T3/da active
- 1992-07-01 AU AU23062/92A patent/AU660701B2/en not_active Ceased
- 1992-07-01 WO PCT/US1992/005433 patent/WO1993002060A1/en active IP Right Grant
- 1992-07-01 AT AT92915192T patent/ATE173728T1/de not_active IP Right Cessation
- 1992-07-01 ES ES92915192T patent/ES2123562T3/es not_active Expired - Lifetime
- 1992-07-07 TW TW081105396A patent/TW199891B/zh active
- 1992-07-20 PT PT100710A patent/PT100710B/pt not_active IP Right Cessation
- 1992-07-21 IE IE235992A patent/IE922359A1/en not_active IP Right Cessation
- 1992-07-21 ZA ZA925469A patent/ZA925469B/xx unknown
- 1992-07-21 MY MYPI92001294A patent/MY131277A/en unknown
- 1992-07-21 NZ NZ243651A patent/NZ243651A/en unknown
- 1992-07-21 MX MX9204278A patent/MX9204278A/es unknown
- 1992-07-21 IL IL10257492A patent/IL102574A/en not_active IP Right Cessation
-
1994
- 1994-01-21 NO NO940227A patent/NO940227L/no unknown
- 1994-01-21 FI FI940306A patent/FI940306A0/fi unknown
-
1995
- 1995-04-05 US US08/417,502 patent/US5512689A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| HUT70412A (en) | 1995-10-30 |
| CA2111445A1 (en) | 1993-02-04 |
| DE69227689T2 (de) | 1999-04-22 |
| EP0595868B1 (de) | 1998-11-25 |
| CA2111445C (en) | 1997-02-18 |
| TW199891B (de) | 1993-02-11 |
| FI940306A (fi) | 1994-01-21 |
| JP2671962B2 (ja) | 1997-11-05 |
| PT100710B (pt) | 1999-07-30 |
| AU2306292A (en) | 1993-02-23 |
| PT100710A (pt) | 1993-09-30 |
| NO940227D0 (no) | 1994-01-21 |
| IL102574A (en) | 1996-07-23 |
| HU9400188D0 (en) | 1994-05-30 |
| ATE173728T1 (de) | 1998-12-15 |
| MX9204278A (es) | 1994-03-31 |
| JPH07502017A (ja) | 1995-03-02 |
| DK0595868T3 (da) | 1999-08-09 |
| MY131277A (en) | 2007-07-31 |
| ZA925469B (en) | 1994-01-21 |
| IE922359A1 (en) | 1993-01-27 |
| US5512689A (en) | 1996-04-30 |
| NZ243651A (en) | 1994-01-26 |
| AU660701B2 (en) | 1995-07-06 |
| NO940227L (no) | 1994-01-21 |
| FI940306A0 (fi) | 1994-01-21 |
| ES2123562T3 (es) | 1999-01-16 |
| IL102574A0 (en) | 1993-01-14 |
| WO1993002060A1 (en) | 1993-02-04 |
| EP0595868A1 (de) | 1994-05-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69227689T2 (de) | Verfahren zur herstellung von (s)-4-[3-(5-methyl-2-phenyl-4-oxazolyl)- 1-hydroxypropyl] brombenzol | |
| AT376424B (de) | Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen | |
| DE69434023D1 (de) | Verfahren zur effizienten Herstellung von 7-ADCA via 2-(carboxyethylthio)acetyl-7-ADCA und 3-(carboxymethylthio)propionyl-7-ADCA | |
| ATE218131T1 (de) | Verfahren zur herstellung von mono-n- substituierten tetraazamakrocyclen | |
| DE68908582T2 (de) | Verfahren zur Herstellung eines keramischen Vorformlings. | |
| DE69500313T2 (de) | Neues verfahren zur herstellung von clonidin-derivaten | |
| DE69106233T2 (de) | Verfahren zur Herstellung von gesintertem Siliciumnitridmaterial. | |
| DE3588014D1 (de) | Verfahren zur herstellung bissilylierter 3-iodmethylcephalosporinderivaten. | |
| ATE238261T1 (de) | Verfahren zur herstellung von orthoestern | |
| DE69223765T2 (de) | Verfahren zur Herstellung eines keramischen Spiegels. | |
| ATE175408T1 (de) | Verfahren zur herstellung von trans-(5r)-2,4,5- trisubstituierten 2-oxazolinen | |
| ATE180481T1 (de) | Verfahren zur herstellung von (-)-trans-n-p- fluorbenzoylmethyl-4-(p-fluorphenyl)-3-((3,4- (methylendioxy)phenoxy>methyl>-piperidin | |
| ATE126208T1 (de) | Verfahren zur herstellung von alpha- ((dialkylamino)substituiertes-methylen)-beta-ox - (substituiertes)-propannitrile. | |
| ATE196632T1 (de) | Verfahren zur herstellung von cephalosporinen | |
| ATE193284T1 (de) | Verfahren zur herstellung von benzylsubstituierten rhodaninederivaten | |
| ATE222245T1 (de) | Verfahren zur herstellung von benzyl- substituierten rhodanin derivaten | |
| DE59108700D1 (de) | Verfahren zur herstellung von 17-oxosteroiden | |
| DE3575922D1 (de) | Verfahren zur herstellung von 3,5-disubstituierten isoxazolen. | |
| DE3878451T2 (de) | Verfahren zur herstellung supraleitender keramischer materialien. | |
| DE58907537D1 (de) | Verfahren zur Herstellung eines Pyrrol-Derivats. | |
| ATE7500T1 (de) | Verfahren zur herstellung neuer sauerstoffhaltiger heterocyclen. | |
| ATA431583A (de) | Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |