MX9204278A - Procedimiento para hipoglicemicos e intermediarios de tiazolidin-2,4-diona quiral. - Google Patents

Procedimiento para hipoglicemicos e intermediarios de tiazolidin-2,4-diona quiral.

Info

Publication number
MX9204278A
MX9204278A MX9204278A MX9204278A MX9204278A MX 9204278 A MX9204278 A MX 9204278A MX 9204278 A MX9204278 A MX 9204278A MX 9204278 A MX9204278 A MX 9204278A MX 9204278 A MX9204278 A MX 9204278A
Authority
MX
Mexico
Prior art keywords
tiazolidin
quiral
diona
intermediaries
hypoglycemic
Prior art date
Application number
MX9204278A
Other languages
English (en)
Inventor
George J Quallich
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of MX9204278A publication Critical patent/MX9204278A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Un procedimiento para la preparación estereoselectiva de intermedios en la preparación de tiazolidin-2,4-dionas quirales potentes hipoglicémicos.
MX9204278A 1991-07-22 1992-07-21 Procedimiento para hipoglicemicos e intermediarios de tiazolidin-2,4-diona quiral. MX9204278A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73356491A 1991-07-22 1991-07-22

Publications (1)

Publication Number Publication Date
MX9204278A true MX9204278A (es) 1994-03-31

Family

ID=24948157

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9204278A MX9204278A (es) 1991-07-22 1992-07-21 Procedimiento para hipoglicemicos e intermediarios de tiazolidin-2,4-diona quiral.

Country Status (21)

Country Link
US (1) US5512689A (es)
EP (1) EP0595868B1 (es)
JP (1) JP2671962B2 (es)
AT (1) ATE173728T1 (es)
AU (1) AU660701B2 (es)
CA (1) CA2111445C (es)
DE (1) DE69227689T2 (es)
DK (1) DK0595868T3 (es)
ES (1) ES2123562T3 (es)
FI (1) FI940306A0 (es)
HU (1) HUT70412A (es)
IE (1) IE922359A1 (es)
IL (1) IL102574A (es)
MX (1) MX9204278A (es)
MY (1) MY131277A (es)
NO (1) NO940227L (es)
NZ (1) NZ243651A (es)
PT (1) PT100710B (es)
TW (1) TW199891B (es)
WO (1) WO1993002060A1 (es)
ZA (1) ZA925469B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU660187B2 (en) * 1991-07-22 1995-06-15 Pfizer Inc. Chiral intermediates for the preparation of antidiabetics thiazoles
FR2699172B1 (fr) * 1992-12-11 1995-01-20 Adir Nouveaux dérivés de 4-méthyl-1,3-oxazole, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
TW416958B (en) * 1993-05-14 2001-01-01 Pfizer Enantioselective oxazaborolidine catalysts
CA2383347A1 (en) * 1999-08-31 2001-03-08 Maxia Pharmaceuticals, Inc. Benzylidene-thiazolidinediones and analogues and their use in the treatment of diabetes
IL157740A0 (en) 2001-03-07 2004-03-28 Incyte San Diego Inc Heterocyclic derivatives and pharmaceutical compositions containing the same
US7265139B2 (en) * 2001-03-08 2007-09-04 Incyte San Diego Inc. RXR activating molecules
CA2340824A1 (en) * 2001-03-14 2002-09-14 Ibm Canada Limited-Ibm Canada Limitee Method and system for application behavior analysis
EP1421061A4 (en) * 2001-08-17 2004-12-22 Incyte San Diego Inc OXIME DERIVATIVES FOR THE TREATMENT OF DYSLIPIDEMIA AND HYPERCHOLESTEROLEMIA
AU2002352706A1 (en) * 2001-11-15 2003-06-10 Maxia Pharmaceuticals, Inc. N-substituted heterocycles for the treatment of hypercholesteremia, dyslipidemia and other metabolic disorders, cancer, and other diseases
US7196108B2 (en) * 2002-03-08 2007-03-27 Incyte San Diego Inc. Bicyclic heterocycles for the treatment of diabetes and other diseases
US7102000B2 (en) * 2002-03-08 2006-09-05 Incyte San Diego Inc. Heterocyclic amide derivatives for the treatment of diabetes and other diseases
WO2004066952A2 (en) * 2003-01-29 2004-08-12 Incyte Corporation Benzoxazole, benzothiazole, and benzimidazole derivatives for the treatment of cancer and other diseases
EP1643993A2 (en) * 2003-04-18 2006-04-12 Incyte San Diego Incorporated Substituted isochroman compounds for the treatment of metabolic disorders, cancer and other diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4943635A (en) * 1987-08-27 1990-07-24 President & Fellows Of Harvard College Enantioselective reduction of ketones
US5036079A (en) * 1989-12-07 1991-07-30 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
TW222626B (es) * 1991-07-22 1994-04-21 Pfizer

Also Published As

Publication number Publication date
HUT70412A (en) 1995-10-30
CA2111445A1 (en) 1993-02-04
DE69227689T2 (de) 1999-04-22
EP0595868B1 (en) 1998-11-25
CA2111445C (en) 1997-02-18
TW199891B (es) 1993-02-11
FI940306A (fi) 1994-01-21
JP2671962B2 (ja) 1997-11-05
PT100710B (pt) 1999-07-30
AU2306292A (en) 1993-02-23
PT100710A (pt) 1993-09-30
NO940227D0 (no) 1994-01-21
IL102574A (en) 1996-07-23
HU9400188D0 (en) 1994-05-30
ATE173728T1 (de) 1998-12-15
JPH07502017A (ja) 1995-03-02
DK0595868T3 (da) 1999-08-09
MY131277A (en) 2007-07-31
ZA925469B (en) 1994-01-21
IE922359A1 (en) 1993-01-27
US5512689A (en) 1996-04-30
DE69227689D1 (de) 1999-01-07
NZ243651A (en) 1994-01-26
AU660701B2 (en) 1995-07-06
NO940227L (no) 1994-01-21
FI940306A0 (fi) 1994-01-21
ES2123562T3 (es) 1999-01-16
IL102574A0 (en) 1993-01-14
WO1993002060A1 (en) 1993-02-04
EP0595868A1 (en) 1994-05-11

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