DK0586376T3 - Fremgangsmåde og mellemprodukter til fremstilling af anxiolytiske perhydro-1H-pyrido 1,2-a pyraziner - Google Patents

Fremgangsmåde og mellemprodukter til fremstilling af anxiolytiske perhydro-1H-pyrido 1,2-a pyraziner

Info

Publication number
DK0586376T3
DK0586376T3 DK92900722.7T DK92900722T DK0586376T3 DK 0586376 T3 DK0586376 T3 DK 0586376T3 DK 92900722 T DK92900722 T DK 92900722T DK 0586376 T3 DK0586376 T3 DK 0586376T3
Authority
DK
Denmark
Prior art keywords
pyrido
intermediates
phthalimido
pyrazines
perhydro
Prior art date
Application number
DK92900722.7T
Other languages
Danish (da)
English (en)
Inventor
Dennis Michael Godek
Charles William Murtiashaw
Frank John Urban
Brian Clement Vanderplas
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of DK0586376T3 publication Critical patent/DK0586376T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Reinforced Plastic Materials (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK92900722.7T 1991-02-27 1991-11-19 Fremgangsmåde og mellemprodukter til fremstilling af anxiolytiske perhydro-1H-pyrido 1,2-a pyraziner DK0586376T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/661,730 US5185449A (en) 1991-02-27 1991-02-27 Process and intermediate for certain bis-aza-bicyclic anxiolytic agents

Publications (1)

Publication Number Publication Date
DK0586376T3 true DK0586376T3 (da) 1997-10-27

Family

ID=24654869

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92900722.7T DK0586376T3 (da) 1991-02-27 1991-11-19 Fremgangsmåde og mellemprodukter til fremstilling af anxiolytiske perhydro-1H-pyrido 1,2-a pyraziner

Country Status (23)

Country Link
US (1) US5185449A (fr)
EP (1) EP0586376B1 (fr)
JP (1) JPH0784467B2 (fr)
KR (1) KR100189044B1 (fr)
AT (1) ATE153662T1 (fr)
AU (1) AU647562B2 (fr)
CA (1) CA2101433C (fr)
DE (1) DE69126326T2 (fr)
DK (1) DK0586376T3 (fr)
ES (1) ES2101831T3 (fr)
FI (1) FI107153B (fr)
GR (1) GR3024125T3 (fr)
HU (2) HUT67440A (fr)
IE (1) IE920600A1 (fr)
IL (1) IL101022A (fr)
MX (1) MX9200802A (fr)
MY (1) MY110167A (fr)
NO (1) NO302947B1 (fr)
NZ (1) NZ241738A (fr)
PT (1) PT100161B (fr)
TW (1) TW268949B (fr)
WO (1) WO1992015575A1 (fr)
ZA (1) ZA921406B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69218414T2 (de) * 1991-02-27 1998-01-22 Pfizer Verfahren zur herstellung von trans-piperidin-2,5-dicarboxylaten
ES2166830T3 (es) * 1994-09-30 2002-05-01 Pfizer Derivados 2,7-sustituidos de octahidro-1h-pirido(1,2-a)pirazina.
WO1996010570A1 (fr) * 1994-09-30 1996-04-11 Pfizer Inc. PERHYDRO-1H-PYRIDO[1,2-a] PYRAZINES DISUBSTITUEES EN 2,7 A ACTION NEUROLEPTIQUE
US6670476B2 (en) 2000-11-29 2003-12-30 Pfizer Inc. Resolution of trans-7-(hydroxy-methyl)octa-hydro-2H-pyrido[1,2-a]pyrazine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3388128A (en) * 1965-09-03 1968-06-11 Allan R. Day Substituted 1, 4-diazabicyclo [4. 4. 9] decanes
WO1990008148A1 (fr) * 1989-01-23 1990-07-26 Pfizer Inc. Agents anxiolytiques bis-aza-bicycliques
DE69218414T2 (de) * 1991-02-27 1998-01-22 Pfizer Verfahren zur herstellung von trans-piperidin-2,5-dicarboxylaten

Also Published As

Publication number Publication date
EP0586376B1 (fr) 1997-05-28
ZA921406B (en) 1993-08-26
AU647562B2 (en) 1994-03-24
HU9302428D0 (en) 1993-11-29
PT100161B (pt) 1999-09-30
ES2101831T3 (es) 1997-07-16
KR100189044B1 (ko) 1999-06-01
DE69126326D1 (de) 1997-07-03
HUT67440A (en) 1995-04-28
HU223138B1 (hu) 2004-03-29
JPH0784467B2 (ja) 1995-09-13
NO933048L (no) 1993-08-26
PT100161A (pt) 1993-05-31
IL101022A0 (en) 1992-11-15
AU9066691A (en) 1992-10-06
US5185449A (en) 1993-02-09
IE920600A1 (en) 1992-09-09
WO1992015575A1 (fr) 1992-09-17
CA2101433A1 (fr) 1992-08-28
FI933754A0 (fi) 1993-08-26
NO933048D0 (no) 1993-08-26
NO302947B1 (no) 1998-05-11
JPH06501021A (ja) 1994-01-27
CA2101433C (fr) 1999-07-27
MX9200802A (es) 1992-08-01
DE69126326T2 (de) 1997-09-04
NZ241738A (en) 1993-05-26
TW268949B (fr) 1996-01-21
IL101022A (en) 1996-06-18
FI107153B (fi) 2001-06-15
FI933754A (fi) 1993-08-26
EP0586376A1 (fr) 1994-03-16
GR3024125T3 (en) 1997-10-31
ATE153662T1 (de) 1997-06-15
MY110167A (en) 1998-02-28

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