HUT67440A - Novel process for producing alkyl-4,6,7,8,9,9a-hexahydro-2h,3h-pyrido[1,2-a]pyrazin-1-on-7-carboxylate esters - Google Patents

Novel process for producing alkyl-4,6,7,8,9,9a-hexahydro-2h,3h-pyrido[1,2-a]pyrazin-1-on-7-carboxylate esters

Info

Publication number
HUT67440A
HUT67440A HU9302428A HU242893A HUT67440A HU T67440 A HUT67440 A HU T67440A HU 9302428 A HU9302428 A HU 9302428A HU 242893 A HU242893 A HU 242893A HU T67440 A HUT67440 A HU T67440A
Authority
HU
Hungary
Prior art keywords
pyrazin
pyrido
hexahydro
carboxylate esters
alkyl
Prior art date
Application number
HU9302428A
Other languages
English (en)
Other versions
HU9302428D0 (en
Inventor
Charles William Murtiashaw
Frank John Urban
Dennis Mihcael Godek
Brian Clement Vanderplas
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of HU9302428D0 publication Critical patent/HU9302428D0/hu
Publication of HUT67440A publication Critical patent/HUT67440A/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Reinforced Plastic Materials (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HU9302428A 1991-02-27 1991-11-19 Novel process for producing alkyl-4,6,7,8,9,9a-hexahydro-2h,3h-pyrido[1,2-a]pyrazin-1-on-7-carboxylate esters HUT67440A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/661,730 US5185449A (en) 1991-02-27 1991-02-27 Process and intermediate for certain bis-aza-bicyclic anxiolytic agents

Publications (2)

Publication Number Publication Date
HU9302428D0 HU9302428D0 (en) 1993-11-29
HUT67440A true HUT67440A (en) 1995-04-28

Family

ID=24654869

Family Applications (2)

Application Number Title Priority Date Filing Date
HU9302428A HUT67440A (en) 1991-02-27 1991-11-19 Novel process for producing alkyl-4,6,7,8,9,9a-hexahydro-2h,3h-pyrido[1,2-a]pyrazin-1-on-7-carboxylate esters
HU9302428A HU223138B1 (hu) 1991-02-27 1991-11-19 Új eljárás racém alkil-4,6,7,8,9,9a-hexahidro-2H, 3H-pirido-[1,2-a] pirazin-1-on-7-karbonsavészterek előállítására

Family Applications After (1)

Application Number Title Priority Date Filing Date
HU9302428A HU223138B1 (hu) 1991-02-27 1991-11-19 Új eljárás racém alkil-4,6,7,8,9,9a-hexahidro-2H, 3H-pirido-[1,2-a] pirazin-1-on-7-karbonsavészterek előállítására

Country Status (23)

Country Link
US (1) US5185449A (hu)
EP (1) EP0586376B1 (hu)
JP (1) JPH0784467B2 (hu)
KR (1) KR100189044B1 (hu)
AT (1) ATE153662T1 (hu)
AU (1) AU647562B2 (hu)
CA (1) CA2101433C (hu)
DE (1) DE69126326T2 (hu)
DK (1) DK0586376T3 (hu)
ES (1) ES2101831T3 (hu)
FI (1) FI107153B (hu)
GR (1) GR3024125T3 (hu)
HU (2) HUT67440A (hu)
IE (1) IE920600A1 (hu)
IL (1) IL101022A (hu)
MX (1) MX9200802A (hu)
MY (1) MY110167A (hu)
NO (1) NO302947B1 (hu)
NZ (1) NZ241738A (hu)
PT (1) PT100161B (hu)
TW (1) TW268949B (hu)
WO (1) WO1992015575A1 (hu)
ZA (1) ZA921406B (hu)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE150453T1 (de) * 1991-02-27 1997-04-15 Pfizer Verfahren zur herstellung von trans-piperidin-2,5-dicarboxylaten
HUT77354A (hu) * 1994-09-30 1998-03-30 Pfizer Inc. 2,7-Szubsztituált oktahidro-1H-pirido[1,2-a]pirazin-származékok, ezeket tartalmazó gyógyszerkészítmények és intermedierek
US5731307A (en) * 1994-09-30 1998-03-24 Pfizer, Inc. Neuroleptic 2,7-disubtituted perhydro-1h-pyrido 1, 2-A!pyrazines
US6670476B2 (en) 2000-11-29 2003-12-30 Pfizer Inc. Resolution of trans-7-(hydroxy-methyl)octa-hydro-2H-pyrido[1,2-a]pyrazine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3388128A (en) * 1965-09-03 1968-06-11 Allan R. Day Substituted 1, 4-diazabicyclo [4. 4. 9] decanes
MX19222A (es) * 1989-01-23 1993-12-01 Pfizer Agentes ansioliticos bis-aza-biciclicos
ATE150453T1 (de) * 1991-02-27 1997-04-15 Pfizer Verfahren zur herstellung von trans-piperidin-2,5-dicarboxylaten

Also Published As

Publication number Publication date
FI107153B (fi) 2001-06-15
US5185449A (en) 1993-02-09
MY110167A (en) 1998-02-28
MX9200802A (es) 1992-08-01
IL101022A (en) 1996-06-18
EP0586376A1 (en) 1994-03-16
DK0586376T3 (da) 1997-10-27
CA2101433C (en) 1999-07-27
NO933048D0 (no) 1993-08-26
IL101022A0 (en) 1992-11-15
WO1992015575A1 (en) 1992-09-17
HU9302428D0 (en) 1993-11-29
JPH0784467B2 (ja) 1995-09-13
PT100161A (pt) 1993-05-31
DE69126326D1 (de) 1997-07-03
FI933754A0 (fi) 1993-08-26
ES2101831T3 (es) 1997-07-16
ZA921406B (en) 1993-08-26
DE69126326T2 (de) 1997-09-04
JPH06501021A (ja) 1994-01-27
GR3024125T3 (en) 1997-10-31
NO933048L (no) 1993-08-26
NZ241738A (en) 1993-05-26
FI933754A (fi) 1993-08-26
IE920600A1 (en) 1992-09-09
KR100189044B1 (ko) 1999-06-01
PT100161B (pt) 1999-09-30
AU9066691A (en) 1992-10-06
TW268949B (hu) 1996-01-21
CA2101433A1 (en) 1992-08-28
EP0586376B1 (en) 1997-05-28
AU647562B2 (en) 1994-03-24
HU223138B1 (hu) 2004-03-29
NO302947B1 (no) 1998-05-11
ATE153662T1 (de) 1997-06-15

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