DK0586376T3 - Fremgangsmåde og mellemprodukter til fremstilling af anxiolytiske perhydro-1H-pyrido 1,2-a pyraziner - Google Patents

Fremgangsmåde og mellemprodukter til fremstilling af anxiolytiske perhydro-1H-pyrido 1,2-a pyraziner

Info

Publication number
DK0586376T3
DK0586376T3 DK92900722.7T DK92900722T DK0586376T3 DK 0586376 T3 DK0586376 T3 DK 0586376T3 DK 92900722 T DK92900722 T DK 92900722T DK 0586376 T3 DK0586376 T3 DK 0586376T3
Authority
DK
Denmark
Prior art keywords
pyrido
intermediates
phthalimido
pyrazines
perhydro
Prior art date
Application number
DK92900722.7T
Other languages
English (en)
Inventor
Dennis Michael Godek
Charles William Murtiashaw
Frank John Urban
Brian Clement Vanderplas
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of DK0586376T3 publication Critical patent/DK0586376T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Reinforced Plastic Materials (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK92900722.7T 1991-02-27 1991-11-19 Fremgangsmåde og mellemprodukter til fremstilling af anxiolytiske perhydro-1H-pyrido 1,2-a pyraziner DK0586376T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/661,730 US5185449A (en) 1991-02-27 1991-02-27 Process and intermediate for certain bis-aza-bicyclic anxiolytic agents

Publications (1)

Publication Number Publication Date
DK0586376T3 true DK0586376T3 (da) 1997-10-27

Family

ID=24654869

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92900722.7T DK0586376T3 (da) 1991-02-27 1991-11-19 Fremgangsmåde og mellemprodukter til fremstilling af anxiolytiske perhydro-1H-pyrido 1,2-a pyraziner

Country Status (23)

Country Link
US (1) US5185449A (da)
EP (1) EP0586376B1 (da)
JP (1) JPH0784467B2 (da)
KR (1) KR100189044B1 (da)
AT (1) ATE153662T1 (da)
AU (1) AU647562B2 (da)
CA (1) CA2101433C (da)
DE (1) DE69126326T2 (da)
DK (1) DK0586376T3 (da)
ES (1) ES2101831T3 (da)
FI (1) FI107153B (da)
GR (1) GR3024125T3 (da)
HU (2) HUT67440A (da)
IE (1) IE920600A1 (da)
IL (1) IL101022A (da)
MX (1) MX9200802A (da)
MY (1) MY110167A (da)
NO (1) NO302947B1 (da)
NZ (1) NZ241738A (da)
PT (1) PT100161B (da)
TW (1) TW268949B (da)
WO (1) WO1992015575A1 (da)
ZA (1) ZA921406B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE150453T1 (de) * 1991-02-27 1997-04-15 Pfizer Verfahren zur herstellung von trans-piperidin-2,5-dicarboxylaten
HUT77354A (hu) * 1994-09-30 1998-03-30 Pfizer Inc. 2,7-Szubsztituált oktahidro-1H-pirido[1,2-a]pirazin-származékok, ezeket tartalmazó gyógyszerkészítmények és intermedierek
US5731307A (en) * 1994-09-30 1998-03-24 Pfizer, Inc. Neuroleptic 2,7-disubtituted perhydro-1h-pyrido 1, 2-A!pyrazines
US6670476B2 (en) 2000-11-29 2003-12-30 Pfizer Inc. Resolution of trans-7-(hydroxy-methyl)octa-hydro-2H-pyrido[1,2-a]pyrazine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3388128A (en) * 1965-09-03 1968-06-11 Allan R. Day Substituted 1, 4-diazabicyclo [4. 4. 9] decanes
MX19222A (es) * 1989-01-23 1993-12-01 Pfizer Agentes ansioliticos bis-aza-biciclicos
ATE150453T1 (de) * 1991-02-27 1997-04-15 Pfizer Verfahren zur herstellung von trans-piperidin-2,5-dicarboxylaten

Also Published As

Publication number Publication date
FI107153B (fi) 2001-06-15
US5185449A (en) 1993-02-09
MY110167A (en) 1998-02-28
MX9200802A (es) 1992-08-01
IL101022A (en) 1996-06-18
EP0586376A1 (en) 1994-03-16
CA2101433C (en) 1999-07-27
NO933048D0 (no) 1993-08-26
IL101022A0 (en) 1992-11-15
WO1992015575A1 (en) 1992-09-17
HU9302428D0 (en) 1993-11-29
JPH0784467B2 (ja) 1995-09-13
PT100161A (pt) 1993-05-31
DE69126326D1 (de) 1997-07-03
FI933754A0 (fi) 1993-08-26
ES2101831T3 (es) 1997-07-16
ZA921406B (en) 1993-08-26
HUT67440A (en) 1995-04-28
DE69126326T2 (de) 1997-09-04
JPH06501021A (ja) 1994-01-27
GR3024125T3 (en) 1997-10-31
NO933048L (no) 1993-08-26
NZ241738A (en) 1993-05-26
FI933754A (fi) 1993-08-26
IE920600A1 (en) 1992-09-09
KR100189044B1 (ko) 1999-06-01
PT100161B (pt) 1999-09-30
AU9066691A (en) 1992-10-06
TW268949B (da) 1996-01-21
CA2101433A1 (en) 1992-08-28
EP0586376B1 (en) 1997-05-28
AU647562B2 (en) 1994-03-24
HU223138B1 (hu) 2004-03-29
NO302947B1 (no) 1998-05-11
ATE153662T1 (de) 1997-06-15

Similar Documents

Publication Publication Date Title
ATE294182T1 (de) Zwischenprodukte zur herstellung von camptothecin und analogen
DK0645389T3 (da) Fremgangsmåde til fremstilling af imidazopyridinderivater
DK0556080T3 (da) Biocykliske pyridinderivater, fremgangsmåde til deres fremstilling, mellemprodukter, deres anvendelse som lægemidler og farmaceutiske præparater med indhold deraf
ES2101960T3 (es) Lactamas benzo-condensadas.
EP0291799A3 (en) Dioxyalkylenearyl-dihydropyridines and their intermediary compounds, process for their preparation and their use
ATE54913T1 (de) Industrielle verbindungen anwendbar als zwischenprodukte in der herstellung von in stellung 2 substituierten 4-hydroxy 3quinolincarboxamid-derivaten und die herstellung von diesen zwischenprodukten.
DK0586376T3 (da) Fremgangsmåde og mellemprodukter til fremstilling af anxiolytiske perhydro-1H-pyrido 1,2-a pyraziner
FI924110A (fi) Menetelmä dihydropyridiinijohdannaisten valmistamiseksi, jotka ovat käyttökelpoisia kasvainten vastaisessa terapiassa
FI832739A0 (fi) 5-alkyl-1,6-naftyridin-2(1h)-oner, mellanprodukter deras framstaellning och anvaendning som hjaertlaekemedel
DK18186A (da) Aminoacrylsyre-derivater, deres fremstilling og anvendelse, samt vedfremstillingen anvendelige mellemprodukter og fremstillingderaf
DE69218414D1 (de) Verfahren zur herstellung von trans-piperidin-2,5-dicarboxylaten
DK659089D0 (da) Mevalonolactoner af pyrazolopyridintypen
DE3864286D1 (de) Herstellungsverfahren von trifluormethylverbindungen.
PT84061A (en) Process for the preparation of monosulfactams
FI883456A (fi) Azabicykloalkankarboxylsyraderivat och foerfarande foer deras framstaellning.
JPS5735573A (en) Novel 3-alkyl substituted 2,4(1h,3h)-quinazolinedione derivative
IT1254201B (it) Procedimento per la preparazione di derivati del glicerolo otticamente attivi.