DK659089A - Mevalonolactoner af pyrazolopyridintypen - Google Patents

Mevalonolactoner af pyrazolopyridintypen Download PDF

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Publication number
DK659089A
DK659089A DK659089A DK659089A DK659089A DK 659089 A DK659089 A DK 659089A DK 659089 A DK659089 A DK 659089A DK 659089 A DK659089 A DK 659089A DK 659089 A DK659089 A DK 659089A
Authority
DK
Denmark
Prior art keywords
mevalonolactons
pyrazolopyridine
type
pyrazolopyridine type
chem
Prior art date
Application number
DK659089A
Other languages
English (en)
Other versions
DK659089D0 (da
Inventor
Yoshihiro Fujikawa
Mikio Suzuki
Hiroshi Iwasaki
Mitsuaki Sakashita
Masaki Kitahara
Original Assignee
Nissan Chemical Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissan Chemical Ind Ltd filed Critical Nissan Chemical Ind Ltd
Publication of DK659089D0 publication Critical patent/DK659089D0/da
Publication of DK659089A publication Critical patent/DK659089A/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Enzymes And Modification Thereof (AREA)
DK659089A 1988-04-26 1989-12-22 Mevalonolactoner af pyrazolopyridintypen DK659089A (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP10309088 1988-04-26
JP27143988 1988-10-27
JP1684689 1989-01-26
PCT/JP1989/000423 WO1989010365A1 (en) 1988-04-26 1989-04-19 Pyrazolopyridine type mevalonolactones

Publications (2)

Publication Number Publication Date
DK659089D0 DK659089D0 (da) 1989-12-22
DK659089A true DK659089A (da) 1989-12-22

Family

ID=27281590

Family Applications (1)

Application Number Title Priority Date Filing Date
DK659089A DK659089A (da) 1988-04-26 1989-12-22 Mevalonolactoner af pyrazolopyridintypen

Country Status (10)

Country Link
EP (1) EP0339358B1 (da)
JP (1) JP2890448B2 (da)
KR (1) KR970009222B1 (da)
AT (1) ATE108450T1 (da)
DE (1) DE68916685T2 (da)
DK (1) DK659089A (da)
FI (1) FI90870C (da)
HU (1) HU203888B (da)
NO (1) NO173501C (da)
WO (1) WO1989010365A1 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3130342B2 (ja) * 1991-10-04 2001-01-31 日産化学工業株式会社 動脈硬化性血管内膜肥厚抑制薬
AU2001242795A1 (en) * 2000-03-27 2001-10-08 Takeda Chemical Industries Ltd. Condensed pyrazole derivatives, process for producing the same and use thereof
EP2170884A2 (en) * 2007-06-25 2010-04-07 Boehringer Ingelheim International GmbH Chemical compounds
WO2009073300A1 (en) 2007-11-02 2009-06-11 Vertex Pharmaceuticals Incorporated [1h- pyrazolo [3, 4-b] pyridine-4-yl] -phenyle or -pyridin-2-yle derivatives as protein kinase c-theta
JP6189948B2 (ja) 2012-06-29 2017-08-30 ファイザー・インク LRRK2阻害薬としての新規な4−(置換アミノ)−7H−ピロロ[2,3−d]ピリミジン
US9695171B2 (en) 2013-12-17 2017-07-04 Pfizer Inc. 3,4-disubstituted-1 H-pyrrolo[2,3-b]pyridines and 4,5-disubstituted-7H-pyrrolo[2,3-c]pyridazines as LRRK2 inhibitors
RU2722149C1 (ru) 2015-09-14 2020-05-27 Пфайзер Инк. Новые производные имидазо[4,5-c] хинолинов и имидазо[4,5-c][1,5] нафтиридинов в качестве ингибиторов LRRK2

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU204253B (en) * 1982-11-22 1991-12-30 Sandoz Ag Process for producing mevalonolactone analogues and derivatives and pharmaceutical compositions containing them
HU198711B (en) * 1984-06-22 1989-11-28 Sandoz Ag Process for producing mevalolacton, derivatives and pyrazol analogues and pharmaceutical composition containing them
US4761419A (en) * 1987-12-07 1988-08-02 Warner-Lambert Company 6-(((substituted)quinolinyl)ethyl)-and ethenyl)tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis
US4822799A (en) * 1988-01-27 1989-04-18 Sandoz Pharm. Corp. Pyrazolopyridine analogs of mevalonolactone and derivatives thereof useful for inhibiting cholesterol biosynthesis in mammals

Also Published As

Publication number Publication date
EP0339358A1 (en) 1989-11-02
WO1989010365A1 (en) 1989-11-02
HU892751D0 (en) 1990-03-28
DE68916685T2 (de) 1995-02-09
NO173501B (no) 1993-09-13
NO895165L (no) 1989-12-21
HU203888B (en) 1991-10-28
NO895165D0 (no) 1989-12-21
ATE108450T1 (de) 1994-07-15
FI896251A0 (fi) 1989-12-22
JPH02275878A (ja) 1990-11-09
NO173501C (no) 1993-12-22
EP0339358B1 (en) 1994-07-13
DE68916685D1 (de) 1994-08-18
DK659089D0 (da) 1989-12-22
FI90870C (fi) 1994-04-11
KR900700480A (ko) 1990-08-13
KR970009222B1 (ko) 1997-06-09
FI90870B (fi) 1993-12-31
JP2890448B2 (ja) 1999-05-17

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Legal Events

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AHS Application shelved for other reasons than non-payment