NO895165L - Pyrazolopyridin-type mevalono-laktoner. - Google Patents

Pyrazolopyridin-type mevalono-laktoner.

Info

Publication number
NO895165L
NO895165L NO89895165A NO895165A NO895165L NO 895165 L NO895165 L NO 895165L NO 89895165 A NO89895165 A NO 89895165A NO 895165 A NO895165 A NO 895165A NO 895165 L NO895165 L NO 895165L
Authority
NO
Norway
Prior art keywords
laktoner
mevalono
pyrazolopyridine
type
pyrazolopyridine type
Prior art date
Application number
NO89895165A
Other languages
English (en)
Other versions
NO173501C (no
NO173501B (no
NO895165D0 (no
Inventor
Yoshihiro Fujikawa
Mikio Suzuki
Hiroshi Iwasaki
Mitsuaki Sakashita
Masaki Kitahara
Original Assignee
Nissan Chemical Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissan Chemical Ind Ltd filed Critical Nissan Chemical Ind Ltd
Publication of NO895165L publication Critical patent/NO895165L/no
Publication of NO895165D0 publication Critical patent/NO895165D0/no
Publication of NO173501B publication Critical patent/NO173501B/no
Publication of NO173501C publication Critical patent/NO173501C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Enzymes And Modification Thereof (AREA)
NO895165A 1988-04-26 1989-12-21 Analogifremgangsmaate ved fremstilling av terapeutisk aktive pyrazolo-pyridinforbindelser NO173501C (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP10309088 1988-04-26
JP27143988 1988-10-27
JP1684689 1989-01-26
PCT/JP1989/000423 WO1989010365A1 (en) 1988-04-26 1989-04-19 Pyrazolopyridine type mevalonolactones

Publications (4)

Publication Number Publication Date
NO895165L true NO895165L (no) 1989-12-21
NO895165D0 NO895165D0 (no) 1989-12-21
NO173501B NO173501B (no) 1993-09-13
NO173501C NO173501C (no) 1993-12-22

Family

ID=27281590

Family Applications (1)

Application Number Title Priority Date Filing Date
NO895165A NO173501C (no) 1988-04-26 1989-12-21 Analogifremgangsmaate ved fremstilling av terapeutisk aktive pyrazolo-pyridinforbindelser

Country Status (10)

Country Link
EP (1) EP0339358B1 (no)
JP (1) JP2890448B2 (no)
KR (1) KR970009222B1 (no)
AT (1) ATE108450T1 (no)
DE (1) DE68916685T2 (no)
DK (1) DK659089D0 (no)
FI (1) FI90870C (no)
HU (1) HU203888B (no)
NO (1) NO173501C (no)
WO (1) WO1989010365A1 (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3130342B2 (ja) * 1991-10-04 2001-01-31 日産化学工業株式会社 動脈硬化性血管内膜肥厚抑制薬
CA2404669A1 (en) 2000-03-27 2001-10-04 Akiko Asakawa Condensed pyrazole derivatives, process for producing the same and use thereof
CA2691888A1 (en) * 2007-06-25 2008-12-31 Boehringer Ingelheim International Gmbh New chemical compounds
NZ585063A (en) 2007-11-02 2012-05-25 Vertex Pharma [1h- pyrazolo [3, 4-b] pyridine-4-yl] -phenyle or -pyridin-2-yle derivatives as protein kinase c-theta
EP2867236B1 (en) 2012-06-29 2017-06-14 Pfizer Inc Novel 4-(substituted-amino)-7h-pyrrolo[2,3-d]pyrimidines as lrrk2 inhibitors
CA2933767C (en) 2013-12-17 2018-11-06 Pfizer Inc. Novel 3,4-disubstituted-1h-pyrrolo[2,3-b]pyridines and 4,5-disubstituted-7h-pyrrolo[2,3-c]pyridazines as lrrk2 inhibitors
CN108137586B (zh) 2015-09-14 2021-04-13 辉瑞大药厂 作为LRRK2抑制剂的新颖咪唑并[4,5-c]喹啉和咪唑并[4,5-c][1,5]萘啶衍生物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1984002131A1 (en) * 1982-11-22 1984-06-07 Sandoz Ag Analogs of mevalolactone and derivatives thereof, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals
KR890001651B1 (ko) * 1984-06-22 1989-05-12 산도즈 파마슈티칼스 코포레이션 메발로노락톤의 피라졸 동족체 및 이의 유도체의 제조방법
US4761419A (en) * 1987-12-07 1988-08-02 Warner-Lambert Company 6-(((substituted)quinolinyl)ethyl)-and ethenyl)tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis
US4822799A (en) * 1988-01-27 1989-04-18 Sandoz Pharm. Corp. Pyrazolopyridine analogs of mevalonolactone and derivatives thereof useful for inhibiting cholesterol biosynthesis in mammals

Also Published As

Publication number Publication date
DE68916685D1 (de) 1994-08-18
ATE108450T1 (de) 1994-07-15
HU203888B (en) 1991-10-28
JP2890448B2 (ja) 1999-05-17
HU892751D0 (en) 1990-03-28
DK659089A (da) 1989-12-22
WO1989010365A1 (en) 1989-11-02
DE68916685T2 (de) 1995-02-09
NO173501C (no) 1993-12-22
EP0339358B1 (en) 1994-07-13
KR900700480A (ko) 1990-08-13
KR970009222B1 (ko) 1997-06-09
FI896251A0 (fi) 1989-12-22
FI90870C (fi) 1994-04-11
EP0339358A1 (en) 1989-11-02
JPH02275878A (ja) 1990-11-09
NO173501B (no) 1993-09-13
DK659089D0 (da) 1989-12-22
FI90870B (fi) 1993-12-31
NO895165D0 (no) 1989-12-21

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