DK0550895T3 - 4,13-dioxabicyclo(8.2.1)-tridecenonderivater, fremgangsmåde og mellemprodukter til fremstilling deraf og lægemidler, der indeholder disse forbindelser - Google Patents

4,13-dioxabicyclo(8.2.1)-tridecenonderivater, fremgangsmåde og mellemprodukter til fremstilling deraf og lægemidler, der indeholder disse forbindelser

Info

Publication number
DK0550895T3
DK0550895T3 DK92122011.7T DK92122011T DK0550895T3 DK 0550895 T3 DK0550895 T3 DK 0550895T3 DK 92122011 T DK92122011 T DK 92122011T DK 0550895 T3 DK0550895 T3 DK 0550895T3
Authority
DK
Denmark
Prior art keywords
derivatives
preparation
tridecenone
dioxabicyclo
intermediates
Prior art date
Application number
DK92122011.7T
Other languages
Danish (da)
English (en)
Inventor
Ulf Preuschoff
Christian Eeckhout
Original Assignee
Solvay Pharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharm Gmbh filed Critical Solvay Pharm Gmbh
Application granted granted Critical
Publication of DK0550895T3 publication Critical patent/DK0550895T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK92122011.7T 1992-01-07 1992-12-24 4,13-dioxabicyclo(8.2.1)-tridecenonderivater, fremgangsmåde og mellemprodukter til fremstilling deraf og lægemidler, der indeholder disse forbindelser DK0550895T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4200145A DE4200145A1 (de) 1992-01-07 1992-01-07 7,10-epoxy-oxacyclododecan-derivate, verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
DK0550895T3 true DK0550895T3 (da) 1997-08-25

Family

ID=6449136

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92122011.7T DK0550895T3 (da) 1992-01-07 1992-12-24 4,13-dioxabicyclo(8.2.1)-tridecenonderivater, fremgangsmåde og mellemprodukter til fremstilling deraf og lægemidler, der indeholder disse forbindelser

Country Status (27)

Country Link
US (1) US5418224A (enExample)
EP (1) EP0550895B1 (enExample)
JP (1) JP3300084B2 (enExample)
KR (1) KR100273937B1 (enExample)
CN (1) CN1033646C (enExample)
AT (1) ATE155478T1 (enExample)
AU (1) AU667699B2 (enExample)
CA (1) CA2086811C (enExample)
CZ (1) CZ281773B6 (enExample)
DE (2) DE4200145A1 (enExample)
DK (1) DK0550895T3 (enExample)
DZ (1) DZ1652A1 (enExample)
ES (1) ES2104808T3 (enExample)
FI (1) FI106862B (enExample)
GR (1) GR3024859T3 (enExample)
HU (2) HU212272B (enExample)
IL (1) IL104158A (enExample)
LT (1) LT3015B (enExample)
LV (1) LV10458B (enExample)
MX (1) MX9300045A (enExample)
NO (1) NO179586C (enExample)
PH (1) PH30098A (enExample)
RU (1) RU2107070C1 (enExample)
SK (1) SK279251B6 (enExample)
TW (1) TW238308B (enExample)
UA (1) UA29393C2 (enExample)
ZA (1) ZA9339B (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP9802433A3 (en) * 1995-10-13 2000-03-28 Neurosearch As 8-azabicyclo[3.2.1]oct-2-ene derivatives, their preparation and use
CA2247929A1 (en) * 1996-03-01 1997-09-04 Miichiro Arita Processes for the preparation of erythromycin derivatives
US6077943A (en) * 1996-03-01 2000-06-20 Takeda Chemical Industries, Ltd. Method of producing erythromycin derivative
DE19644195A1 (de) * 1996-10-24 1998-04-30 Solvay Pharm Gmbh 10,13,15-Trioxatricyclo[9.2.1.1.·9·.·6·]-pentadecanon-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE19805822B4 (de) * 1998-02-13 2009-02-05 Solvay Pharmaceuticals Gmbh 11-Acetyl-12,13-dioxabicyclo[8.2.1]tridecenon-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US6165985A (en) * 1998-02-13 2000-12-26 Solvay Pharmaceuticals Gmbh 11-acetyl-12,13-dioxabicyclo[8.2.1]-tridecenone derivatives, processes for their preparation and pharmaceutical compositions comprising them
HRP980496B1 (en) * 1998-09-10 2007-03-31 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. New thilozine hydroxy derivatives and a process for the preparation thereof
WO2002014338A1 (fr) * 2000-08-17 2002-02-21 The Kitasato Institute Nouveaux derives de pseudoerythromycine
KR100554562B1 (ko) * 2000-09-01 2006-03-03 쥬가이 세이야쿠 가부시키가이샤 에리트로마이신 유도체의 제조 방법
JP2004529184A (ja) * 2001-05-10 2004-09-24 ゾルファイ　ファーマスーティカルズ　ゲゼルシャフト　ミット　ベシュレンクテル　ハフツング 新規１−アミドメチルカルボニル−ピペリジン誘導体、該誘導体を製造するための方法及び中間体並びにこれらの化合物を含有している医薬
US20040067896A1 (en) * 2002-07-25 2004-04-08 The Kitasato Institute Novel pseudoerythromycin derivatives
DE602004025569D1 (de) 2003-06-18 2010-04-01 Tranzyme Pharma Inc Makrozyklische motilin rezeptorantagonisten
US7582611B2 (en) * 2005-05-24 2009-09-01 Pfizer Inc. Motilide compounds
BRPI0619556A2 (pt) * 2005-12-08 2011-10-04 Pfizer processo para desmetilação de grupo 3' -dimetil amino de compostos eritromicina
JP5684474B2 (ja) 2006-09-11 2015-03-11 オセラ セラピューティクス， インコーポレイテッド 胃腸の運動障害疾患の治療のためのモチリン受容体の大環状アンタゴニスト
MX2009005977A (es) * 2006-12-05 2009-06-17 Pfizer Polimorfos de motilida.
US20080287371A1 (en) * 2007-05-17 2008-11-20 Tranzyme Pharma Inc. Macrocyclic antagonists of the motilin receptor for modulation of the migrating motor complex
WO2014156339A1 (ja) * 2013-03-25 2014-10-02 ゼリア新薬工業株式会社 食後期の胃運動亢進剤

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3725385A (en) * 1970-11-02 1973-04-03 Abbott Lab Process for the demethylation of 3-amino macrolides
US5106961A (en) * 1987-05-26 1992-04-21 Eli Lilly And Company Erythromycin ring-contracted derivatives
CA1321581C (en) * 1987-05-26 1993-08-24 Herbert A. Kirst Ring-contracted macrolides
US4920102A (en) 1988-04-18 1990-04-24 Eli Lilly And Company Method for treating gastrointestinal disorders

Also Published As

Publication number Publication date
DZ1652A1 (fr) 2002-02-17
ES2104808T3 (es) 1997-10-16
HU210216A9 (en) 1995-02-28
FI930051A0 (fi) 1993-01-07
MX9300045A (es) 1993-12-01
AU3103693A (en) 1993-07-08
NO930029D0 (no) 1993-01-06
KR930016436A (ko) 1993-08-26
JPH07247299A (ja) 1995-09-26
LT3015B (lt) 1994-08-25
HK1014003A1 (en) 1999-09-17
SK279251B6 (sk) 1998-08-05
DE59208710D1 (de) 1997-08-21
CN1033646C (zh) 1996-12-25
CZ281773B6 (cs) 1997-01-15
EP0550895A1 (de) 1993-07-14
NO179586C (no) 1996-11-06
LTIP187A (lt) 1994-03-25
HU9204076D0 (en) 1993-04-28
HUT66234A (en) 1994-10-28
AU667699B2 (en) 1996-04-04
JP3300084B2 (ja) 2002-07-08
US5418224A (en) 1995-05-23
SK341492A3 (en) 1995-05-10
ZA9339B (en) 1993-08-05
FI930051L (fi) 1993-07-08
ATE155478T1 (de) 1997-08-15
CN1075320A (zh) 1993-08-18
HU212272B (en) 1996-04-29
CZ341492A3 (en) 1993-07-14
FI106862B (fi) 2001-04-30
RU2107070C1 (ru) 1998-03-20
EP0550895B1 (de) 1997-07-16
CA2086811C (en) 2003-12-09
NO930029L (no) 1993-07-08
LV10458B (en) 1996-02-20
CA2086811A1 (en) 1993-07-08
KR100273937B1 (ko) 2000-12-15
GR3024859T3 (en) 1998-01-30
PH30098A (en) 1996-12-27
LV10458A (lv) 1995-02-20
NO179586B (no) 1996-07-29
DE4200145A1 (de) 1993-07-08
UA29393C2 (uk) 2000-11-15
IL104158A0 (en) 1993-05-13
TW238308B (enExample) 1995-01-11
IL104158A (en) 1997-07-13

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