DK0550895T3 - 4,13-dioxabicyclo(8.2.1)-tridecenonderivater, fremgangsmåde og mellemprodukter til fremstilling deraf og lægemidler, der indeholder disse forbindelser - Google Patents

4,13-dioxabicyclo(8.2.1)-tridecenonderivater, fremgangsmåde og mellemprodukter til fremstilling deraf og lægemidler, der indeholder disse forbindelser

Info

Publication number
DK0550895T3
DK0550895T3 DK92122011.7T DK92122011T DK0550895T3 DK 0550895 T3 DK0550895 T3 DK 0550895T3 DK 92122011 T DK92122011 T DK 92122011T DK 0550895 T3 DK0550895 T3 DK 0550895T3
Authority
DK
Denmark
Prior art keywords
derivatives
preparation
tridecenone
dioxabicyclo
intermediates
Prior art date
Application number
DK92122011.7T
Other languages
Danish (da)
English (en)
Inventor
Ulf Preuschoff
Christian Eeckhout
Original Assignee
Solvay Pharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharm Gmbh filed Critical Solvay Pharm Gmbh
Application granted granted Critical
Publication of DK0550895T3 publication Critical patent/DK0550895T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
DK92122011.7T 1992-01-07 1992-12-24 4,13-dioxabicyclo(8.2.1)-tridecenonderivater, fremgangsmåde og mellemprodukter til fremstilling deraf og lægemidler, der indeholder disse forbindelser DK0550895T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4200145A DE4200145A1 (de) 1992-01-07 1992-01-07 7,10-epoxy-oxacyclododecan-derivate, verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
DK0550895T3 true DK0550895T3 (da) 1997-08-25

Family

ID=6449136

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92122011.7T DK0550895T3 (da) 1992-01-07 1992-12-24 4,13-dioxabicyclo(8.2.1)-tridecenonderivater, fremgangsmåde og mellemprodukter til fremstilling deraf og lægemidler, der indeholder disse forbindelser

Country Status (27)

Country Link
US (1) US5418224A (enExample)
EP (1) EP0550895B1 (enExample)
JP (1) JP3300084B2 (enExample)
KR (1) KR100273937B1 (enExample)
CN (1) CN1033646C (enExample)
AT (1) ATE155478T1 (enExample)
AU (1) AU667699B2 (enExample)
CA (1) CA2086811C (enExample)
CZ (1) CZ281773B6 (enExample)
DE (2) DE4200145A1 (enExample)
DK (1) DK0550895T3 (enExample)
DZ (1) DZ1652A1 (enExample)
ES (1) ES2104808T3 (enExample)
FI (1) FI106862B (enExample)
GR (1) GR3024859T3 (enExample)
HU (2) HU212272B (enExample)
IL (1) IL104158A (enExample)
LT (1) LT3015B (enExample)
LV (1) LV10458B (enExample)
MX (1) MX9300045A (enExample)
NO (1) NO179586C (enExample)
PH (1) PH30098A (enExample)
RU (1) RU2107070C1 (enExample)
SK (1) SK279251B6 (enExample)
TW (1) TW238308B (enExample)
UA (1) UA29393C2 (enExample)
ZA (1) ZA9339B (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100274829B1 (ko) * 1995-10-13 2000-12-15 페더 벨링 8-아자바이사이클로[3,2,1]-옥트-2-엔 유도체의 제조방법 및 용도
WO1997031930A1 (fr) * 1996-03-01 1997-09-04 Takeda Chemical Industries, Ltd. Processus de preparation de derives d'erythromycine
US6077943A (en) * 1996-03-01 2000-06-20 Takeda Chemical Industries, Ltd. Method of producing erythromycin derivative
DE19644195A1 (de) * 1996-10-24 1998-04-30 Solvay Pharm Gmbh 10,13,15-Trioxatricyclo[9.2.1.1.·9·.·6·]-pentadecanon-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US6165985A (en) * 1998-02-13 2000-12-26 Solvay Pharmaceuticals Gmbh 11-acetyl-12,13-dioxabicyclo[8.2.1]-tridecenone derivatives, processes for their preparation and pharmaceutical compositions comprising them
DE19805822B4 (de) * 1998-02-13 2009-02-05 Solvay Pharmaceuticals Gmbh 11-Acetyl-12,13-dioxabicyclo[8.2.1]tridecenon-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
HRP980496B1 (en) * 1998-09-10 2007-03-31 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. New thilozine hydroxy derivatives and a process for the preparation thereof
EP1489090B1 (en) * 2000-08-17 2006-02-01 The Kitasato Institute Novel pseudoerythormycin derivatives
JP3944077B2 (ja) * 2000-09-01 2007-07-11 中外製薬株式会社 エリスロマイシン誘導体の製造方法
DE50204789D1 (de) * 2001-05-10 2005-12-08 Solvay Pharm Gmbh Neue 1-amidomethylcarbonyl-piperidinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US20040067896A1 (en) * 2002-07-25 2004-04-08 The Kitasato Institute Novel pseudoerythromycin derivatives
CA2528375C (en) 2003-06-18 2013-11-19 Tranzyme Pharma, Inc. Macrocyclic antagonists of the motilin receptor
US7582611B2 (en) * 2005-05-24 2009-09-01 Pfizer Inc. Motilide compounds
JP2009518396A (ja) * 2005-12-08 2009-05-07 ファイザー・インク エリスロマイシン化合物の３’−ジメチルアミノ基を脱メチルする方法
JP5684474B2 (ja) 2006-09-11 2015-03-11 オセラ セラピューティクス， インコーポレイテッド 胃腸の運動障害疾患の治療のためのモチリン受容体の大環状アンタゴニスト
RU2422453C2 (ru) * 2006-12-05 2011-06-27 Пфайзер Инк. Полиморфы мотилида
US20080287371A1 (en) * 2007-05-17 2008-11-20 Tranzyme Pharma Inc. Macrocyclic antagonists of the motilin receptor for modulation of the migrating motor complex
TWI662967B (zh) * 2013-03-25 2019-06-21 日商志瑞亞新藥工業股份有限公司 食後期之胃運動亢進劑

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3725385A (en) 1970-11-02 1973-04-03 Abbott Lab Process for the demethylation of 3-amino macrolides
US5106961A (en) * 1987-05-26 1992-04-21 Eli Lilly And Company Erythromycin ring-contracted derivatives
CA1321581C (en) * 1987-05-26 1993-08-24 Herbert A. Kirst Ring-contracted macrolides
US4920102A (en) 1988-04-18 1990-04-24 Eli Lilly And Company Method for treating gastrointestinal disorders

Also Published As

Publication number Publication date
TW238308B (enExample) 1995-01-11
HU212272B (en) 1996-04-29
DE4200145A1 (de) 1993-07-08
IL104158A (en) 1997-07-13
LT3015B (lt) 1994-08-25
NO930029D0 (no) 1993-01-06
IL104158A0 (en) 1993-05-13
EP0550895A1 (de) 1993-07-14
KR100273937B1 (ko) 2000-12-15
SK341492A3 (en) 1995-05-10
HUT66234A (en) 1994-10-28
HU9204076D0 (en) 1993-04-28
LV10458A (lv) 1995-02-20
MX9300045A (es) 1993-12-01
CN1075320A (zh) 1993-08-18
NO179586C (no) 1996-11-06
HK1014003A1 (en) 1999-09-17
GR3024859T3 (en) 1998-01-30
ATE155478T1 (de) 1997-08-15
FI930051A0 (fi) 1993-01-07
ES2104808T3 (es) 1997-10-16
EP0550895B1 (de) 1997-07-16
UA29393C2 (uk) 2000-11-15
KR930016436A (ko) 1993-08-26
ZA9339B (en) 1993-08-05
PH30098A (en) 1996-12-27
HU210216A9 (en) 1995-02-28
RU2107070C1 (ru) 1998-03-20
CA2086811A1 (en) 1993-07-08
FI930051L (fi) 1993-07-08
US5418224A (en) 1995-05-23
CZ281773B6 (cs) 1997-01-15
JPH07247299A (ja) 1995-09-26
JP3300084B2 (ja) 2002-07-08
FI106862B (fi) 2001-04-30
NO930029L (no) 1993-07-08
DE59208710D1 (de) 1997-08-21
CZ341492A3 (en) 1993-07-14
NO179586B (no) 1996-07-29
AU667699B2 (en) 1996-04-04
CN1033646C (zh) 1996-12-25
AU3103693A (en) 1993-07-08
CA2086811C (en) 2003-12-09
LTIP187A (lt) 1994-03-25
LV10458B (en) 1996-02-20
DZ1652A1 (fr) 2002-02-17
SK279251B6 (sk) 1998-08-05

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