DK0484936T3 - Suspensioner med tricykliske forbindelser - Google Patents

Suspensioner med tricykliske forbindelser

Info

Publication number
DK0484936T3
DK0484936T3 DK91118982.7T DK91118982T DK0484936T3 DK 0484936 T3 DK0484936 T3 DK 0484936T3 DK 91118982 T DK91118982 T DK 91118982T DK 0484936 T3 DK0484936 T3 DK 0484936T3
Authority
DK
Denmark
Prior art keywords
suspensions
tricyclic compounds
administable
octacos
tetraone
Prior art date
Application number
DK91118982.7T
Other languages
Danish (da)
English (en)
Inventor
Sotoo Asakura
Yasuto Koyama
Youhei Kiyota
Kiyoko Akashi
Akira Kagayama
Yoshio Murakami
Toshiomi Nakate
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB919104834A external-priority patent/GB9104834D0/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Application granted granted Critical
Publication of DK0484936T3 publication Critical patent/DK0484936T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
DK91118982.7T 1990-11-08 1991-11-07 Suspensioner med tricykliske forbindelser DK0484936T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP30483990 1990-11-08
GB919104834A GB9104834D0 (en) 1991-03-07 1991-03-07 New use
JP25935891 1991-10-07

Publications (1)

Publication Number Publication Date
DK0484936T3 true DK0484936T3 (da) 1995-03-27

Family

ID=27265547

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91118982.7T DK0484936T3 (da) 1990-11-08 1991-11-07 Suspensioner med tricykliske forbindelser

Country Status (16)

Country Link
US (2) US5368865A (fr)
EP (1) EP0484936B1 (fr)
JP (1) JP2581359B2 (fr)
KR (1) KR100211085B1 (fr)
CN (1) CN1069195C (fr)
AT (1) ATE112486T1 (fr)
AU (1) AU653556B2 (fr)
CA (1) CA2054983A1 (fr)
DE (1) DE69104460T2 (fr)
DK (1) DK0484936T3 (fr)
ES (1) ES2061149T3 (fr)
HU (1) HU210760B (fr)
IE (1) IE65341B1 (fr)
IL (1) IL100011A (fr)
PT (1) PT99461B (fr)
UA (1) UA26303A1 (fr)

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US6136310A (en) * 1991-07-25 2000-10-24 Idec Pharmaceuticals Corporation Recombinant anti-CD4 antibodies for human therapy
GB9218027D0 (en) * 1992-08-25 1992-10-14 Fisons Plc Novel method of treatment
ES2134860T3 (es) * 1992-11-18 1999-10-16 Fujisawa Pharmaceutical Co Preparacion farmaceutica de accion prolongada.
JPH06345646A (ja) * 1993-06-08 1994-12-20 Fujisawa Pharmaceut Co Ltd ローション剤
NZ295170A (en) * 1994-10-26 1999-02-25 Novartis Ag Topical pharmaceutical compositions comprising a fk506 class compound, an unsaturated fatty alcohol, water and diether alcohol, alkanediol or ether diol as a solvent
AR004480A1 (es) * 1995-04-06 1998-12-16 Amico Derin C D Compuestos de ascomicina que poseen actividad antiinflamatoria, pro cedimiento para prepararlos, uso de dichos compuestos para preparar agentesfarmaceuticos y composiciones farmaceuticas que los incluyen
ZA967887B (en) 1995-09-19 1997-04-07 Fujisawa Pharmaceutical Co Aerosol compositions
GB9601120D0 (en) * 1996-01-19 1996-03-20 Sandoz Ltd Organic compounds
DE19617085A1 (de) * 1996-04-29 1997-10-30 Bayer Ag Verfahren zur Herstellung von feinstteiligen Kristallisationsprodukten
US5827503A (en) * 1996-08-08 1998-10-27 Collagenex Pharmaceuticals, Inc. Method and composition for treating periodontitis
ZA9710927B (en) 1996-12-06 1998-06-15 Fujisawa Pharmaceutical Co Pharmaceutical composition.
TW450810B (en) * 1997-02-20 2001-08-21 Fujisawa Pharmaceutical Co Macrolides antibiotic pharmaceutical composition for preventing and treating skin diseases
EP0978288A4 (fr) 1997-04-11 2006-07-12 Astellas Pharma Inc Composition medicamenteuse
KR20010013072A (ko) * 1997-05-27 2001-02-26 요시다 쇼지 이스라파판트 함유 수성 액제
US6482747B1 (en) * 1997-12-26 2002-11-19 Hitachi, Ltd. Plasma treatment method and plasma treatment apparatus
US6384073B1 (en) * 1998-02-23 2002-05-07 Fujisawa Pharmaceutical Co., Ltd. Use of macrolide compounds for treating glaucoma
AUPP223198A0 (en) * 1998-03-06 1998-04-02 Fujisawa Pharmaceutical Co., Ltd. New use
US7410995B1 (en) 1998-08-14 2008-08-12 Gpi Nil Holdings Inc. N-linked sulfonamide of heterocyclic thioesters for vision and memory disorders
US7265150B1 (en) * 1998-08-14 2007-09-04 Gpi Nil Holdings Inc. Carboxylic acids and carboxylic acid isosteres of N-heterocyclic compounds for vision and memory disorders
US6339101B1 (en) 1998-08-14 2002-01-15 Gpi Nil Holdings, Inc. N-linked sulfonamides of N-heterocyclic carboxylic acids or isosteres for vision and memory disorders
US6335348B1 (en) 1998-08-14 2002-01-01 Gpi Nil Holdings, Inc. Nitrogen-containing linear and azepinyl/ compositions and uses for vision and memory disorders
US6376517B1 (en) * 1998-08-14 2002-04-23 Gpi Nil Holdings, Inc. Pipecolic acid derivatives for vision and memory disorders
US6218423B1 (en) 1998-08-14 2001-04-17 Gpi Nil Holdings, Inc. Pyrrolidine derivatives for vision and memory disorders
US6333340B1 (en) 1998-08-14 2001-12-25 Gpi Nil Holdings, Inc. Small molecule sulfonamides for vision and memory disorders
US7338976B1 (en) 1998-08-14 2008-03-04 Gpi Nil Holdings, Inc. Heterocyclic esters or amides for vision and memory disorders
US6506788B1 (en) 1998-08-14 2003-01-14 Gpi Nil Holdings, Inc. N-linked urea or carbamate of heterocyclic thioesters for vision and memory disorders
US6399648B1 (en) 1998-08-14 2002-06-04 Gpi Nil Holdings, Inc. N-oxides of heterocyclic ester, amide, thioester, or ketone for vision and memory disorders
US6337340B1 (en) 1998-08-14 2002-01-08 Gpi Nil Holdings, Inc. Carboxylic acids and isosteres of heterocyclic ring compounds having multiple heteroatoms for vision and memory disorders
US6384056B1 (en) 1998-08-14 2002-05-07 Gpi Nil Holdings, Inc. Heterocyclic thioesters or ketones for vision and memory disorders
GB9826656D0 (en) 1998-12-03 1999-01-27 Novartis Ag Organic compounds
KR100784653B1 (ko) * 2000-01-26 2007-12-12 교린 세이야꾸 가부시키 가이샤 점안제
WO2002078673A1 (fr) * 2001-03-29 2002-10-10 Takeda Chemical Industries, Ltd. Procede de production d'un medicament sous forme de granules fins
GB0108498D0 (en) * 2001-04-04 2001-05-23 Novartis Ag Organic Compounds
AR033151A1 (es) * 2001-04-12 2003-12-03 Sucampo Pharmaceuticals Inc Agente para el tratamiento oftalmico topico de las enfermedades inflamatorias oculares
AR038628A1 (es) * 2002-03-04 2005-01-19 Novartis Ag Composicion oftalmica
CN1674896A (zh) * 2002-08-09 2005-09-28 苏坎波制药有限公司 含有fk506衍生物的药物组合物及其用于治疗过敏性疾病的用途
DK1539157T3 (da) * 2002-09-18 2013-10-07 Univ Pennsylvania Fremgangsmåde til hæmning af choroidal neovaskularisering
WO2004062669A1 (fr) * 2003-01-16 2004-07-29 Sucampo Ag Utilisation d'un compose macrolide pour le traitement de la secheresse oculaire
JP2007505932A (ja) 2003-09-18 2007-03-15 マクサイト， インコーポレイテッド 経強膜送達
US8663639B2 (en) 2005-02-09 2014-03-04 Santen Pharmaceutical Co., Ltd. Formulations for treating ocular diseases and conditions
CA2597590A1 (fr) 2005-02-09 2006-08-17 Macusight, Inc. Formulations pour un traitement oculaire
US20060252745A1 (en) 2005-05-06 2006-11-09 Almeida Jose L D Methods of preparing pharmaceutical compositions comprising eslicarbazepine acetate and methods of use
US8492400B2 (en) 2006-02-09 2013-07-23 Santen Pharmaceutical Co., Ltd. Stable formulations, and methods of their preparation and use
CN103127100A (zh) 2006-03-23 2013-06-05 参天制药株式会社 用于与血管通透性有关的疾病或病症的制剂和方法
GB0700773D0 (en) 2007-01-15 2007-02-21 Portela & Ca Sa Drug therapies
CL2008000374A1 (es) * 2008-02-05 2008-04-04 Igloo Zone Chile S A Composicion farmaceutica que comprende un polvo para suspension oral de tacrolimus o una de sus sales, hidratos o solvatos y excipientes farmaceuticamente aceptables; procedimiento de preparacion de dicha composicion farmaceutica; y uso para la preve
CN103565738A (zh) * 2012-07-25 2014-02-12 天津金耀集团有限公司 一种快速分散的眼用水混悬液药物
CN103565741A (zh) * 2012-07-25 2014-02-12 天津金耀集团有限公司 一种具有再分散性的糖皮质激素眼用水混悬液
CN104382848B (zh) * 2014-10-20 2017-04-26 齐鲁制药有限公司 一种他克莫司混悬型滴眼液及其制备方法
JPWO2016068208A1 (ja) 2014-10-28 2017-08-10 晃史 山口 妊娠状態を改善するための薬剤及びその利用
CN106074367A (zh) * 2016-07-20 2016-11-09 中山大学中山眼科中心 含fk506类化合物/fkbp蛋白二聚体的药物组合物及其制备方法
CN107595772B (zh) * 2017-09-26 2020-09-18 山东省药学科学院 一种他克莫司纳米混悬滴眼液的制备方法
CN112533599A (zh) 2018-08-10 2021-03-19 山口晃史 与母体和胎儿的关系中的体液免疫相关的疾病的治疗药
US20220062245A1 (en) 2018-12-18 2022-03-03 Koushi Yamaguchi Agent for improving infertility, recurrent miscarriage, and state of pregnancy

Family Cites Families (12)

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US4894366A (en) * 1984-12-03 1990-01-16 Fujisawa Pharmaceutical Company, Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
GB8430455D0 (en) * 1984-12-03 1985-01-09 Fujisawa Pharmaceutical Co Fr-900506 substance
JPS6317884A (ja) * 1986-05-30 1988-01-25 Fujisawa Pharmaceut Co Ltd トリシクロ化合物
AU630866B2 (en) * 1987-12-09 1992-11-12 Fisons Plc Macrocyclic compounds
JPH02178974A (ja) * 1988-12-29 1990-07-11 Fuji Electric Co Ltd 複合ｍｏｓ型半導体素子
DE3844287A1 (de) * 1988-12-30 1990-07-05 Bosch Gmbh Robert Verfahren und vorrichtung zur ueberpruefung eines sicherheitsabstellers bei brennkraftmaschinen, insbesondere dieselmotoren
JPH0335836A (ja) * 1989-07-04 1991-02-15 Seiko Epson Corp タイミングプーリの製造方法
DK0406791T3 (da) * 1989-07-05 1995-03-27 Fujisawa Pharmaceutical Co Vandigt flydende præparat til ekstern anvendelse
US5196305A (en) * 1989-09-12 1993-03-23 Eastman Kodak Company Diagnostic and amplification methods using primers having thymine at 3' end to overcome primer-target mismatch at the 3' end
GB8925797D0 (en) * 1989-11-15 1990-01-04 Fisons Plc Compositions
KR0177158B1 (ko) * 1990-03-01 1999-03-20 후지사와 도모기찌로 면역억제 활성을 갖는 트리사이클릭 화합물 함유 용액 제제
US5260301A (en) * 1990-03-01 1993-11-09 Fujisawa Pharmaceutical Co., Ltd. Pharmaceutical solution containing FK-506

Also Published As

Publication number Publication date
PT99461A (pt) 1992-10-30
CN1069195C (zh) 2001-08-08
IL100011A0 (en) 1992-08-18
JP2581359B2 (ja) 1997-02-12
AU653556B2 (en) 1994-10-06
IE65341B1 (en) 1995-10-18
IL100011A (en) 1995-12-08
ES2061149T3 (es) 1994-12-01
EP0484936A1 (fr) 1992-05-13
PT99461B (pt) 1999-02-26
HU210760B (en) 1995-07-28
US5368865A (en) 1994-11-29
US5496564A (en) 1996-03-05
KR100211085B1 (ko) 1999-07-15
CN1061907A (zh) 1992-06-17
AU8709991A (en) 1992-05-14
HUT60925A (en) 1992-11-30
JPH05155770A (ja) 1993-06-22
KR920009401A (ko) 1992-06-25
CA2054983A1 (fr) 1992-05-09
DE69104460D1 (de) 1994-11-10
IE913861A1 (en) 1992-05-20
DE69104460T2 (de) 1995-02-09
UA26303A1 (uk) 1999-08-30
EP0484936B1 (fr) 1994-10-05
HU913507D0 (en) 1992-01-28
ATE112486T1 (de) 1994-10-15

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