DK0470355T3 - Fremgangsmåde til fremstilling af deoxynucleosider - Google Patents

Fremgangsmåde til fremstilling af deoxynucleosider

Info

Publication number
DK0470355T3
DK0470355T3 DK91110587.2T DK91110587T DK0470355T3 DK 0470355 T3 DK0470355 T3 DK 0470355T3 DK 91110587 T DK91110587 T DK 91110587T DK 0470355 T3 DK0470355 T3 DK 0470355T3
Authority
DK
Denmark
Prior art keywords
preparation
deoxynucleosides
substituted
compound
anhydrothymidine
Prior art date
Application number
DK91110587.2T
Other languages
Danish (da)
English (en)
Inventor
Kenneth E Green
John L Considine Jr
Joseph Dantuono Iii
Thurairajah Padmanathan
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of DK0470355T3 publication Critical patent/DK0470355T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
DK91110587.2T 1990-08-06 1991-06-26 Fremgangsmåde til fremstilling af deoxynucleosider DK0470355T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US56359690A 1990-08-06 1990-08-06

Publications (1)

Publication Number Publication Date
DK0470355T3 true DK0470355T3 (da) 1996-07-15

Family

ID=24251148

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91110587.2T DK0470355T3 (da) 1990-08-06 1991-06-26 Fremgangsmåde til fremstilling af deoxynucleosider

Country Status (21)

Country Link
EP (1) EP0470355B1 (de)
JP (1) JP3026861B2 (de)
KR (1) KR0173319B1 (de)
CN (1) CN1031343C (de)
AT (1) ATE138927T1 (de)
AU (1) AU649698B2 (de)
CA (1) CA2048347C (de)
CZ (1) CZ283988B6 (de)
DE (1) DE69119994T2 (de)
DK (1) DK0470355T3 (de)
ES (1) ES2088443T3 (de)
FI (1) FI102375B (de)
GR (1) GR3020946T3 (de)
HU (1) HU209310B (de)
IE (1) IE912762A1 (de)
IL (1) IL98685A (de)
NZ (1) NZ239213A (de)
PL (1) PL166101B1 (de)
PT (1) PT98554B (de)
SK (1) SK278598B6 (de)
ZA (1) ZA916156B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL100480A0 (en) * 1991-01-15 1992-09-06 American Cyanamid Co Process for the preparation of 3'-fluoropyrimidine nucleosides
GB9309787D0 (en) * 1993-05-12 1993-06-23 Rhone Poulenc Chemicals Purification of fluoronucleosides
GB9309795D0 (en) * 1993-05-12 1993-06-23 Rhone Poulenc Chemicals Preparation of flouro-compounds
US5717086A (en) * 1993-05-12 1998-02-10 Rhone-Poulenc Chemicals Limited Preparation of fluoro-nucleosides and intermediates for use therein
JP3677790B2 (ja) * 1993-08-04 2005-08-03 味の素株式会社 ヌクレオシド誘導体とその製造方法
GB0608876D0 (en) 2006-05-05 2006-06-14 Medivir Ab Combination therapy

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3775397A (en) * 1969-11-12 1973-11-27 Akad Wissenschaften Ddr Novel cytostatic 2',3'-dideoxy-3'-fluoropyrimidine-nucleosides
SE464168B (sv) * 1989-07-19 1991-03-18 Bo Fredrik Oeberg Antiviral komposition bestaaende av en 3'-fluoro-2',3'-dideoxynukleosidfoerening och en 2',3'-dideoxynukleosidfoerening (exempelvis azt)

Also Published As

Publication number Publication date
JP3026861B2 (ja) 2000-03-27
AU8163591A (en) 1992-02-13
DE69119994T2 (de) 1997-01-23
PT98554B (pt) 1999-01-29
KR0173319B1 (ko) 1999-02-18
DE69119994D1 (de) 1996-07-11
FI913722A (fi) 1992-02-07
FI102375B1 (fi) 1998-11-30
KR920004405A (ko) 1992-03-27
AU649698B2 (en) 1994-06-02
PL166101B1 (pl) 1995-03-31
IL98685A0 (en) 1992-07-15
CN1058969A (zh) 1992-02-26
ATE138927T1 (de) 1996-06-15
FI102375B (fi) 1998-11-30
SK278598B6 (en) 1997-11-05
PT98554A (pt) 1992-06-30
JPH04253993A (ja) 1992-09-09
HU209310B (en) 1994-04-28
PL291335A1 (en) 1992-08-24
ZA916156B (en) 1992-04-29
EP0470355A1 (de) 1992-02-12
EP0470355B1 (de) 1996-06-05
IL98685A (en) 1996-08-04
HU912601D0 (en) 1992-01-28
CN1031343C (zh) 1996-03-20
HUT58756A (en) 1992-03-30
CA2048347A1 (en) 1992-02-07
FI913722A0 (fi) 1991-08-05
GR3020946T3 (en) 1996-12-31
CZ283988B6 (cs) 1998-07-15
IE912762A1 (en) 1992-02-12
CS242991A3 (en) 1992-02-19
ES2088443T3 (es) 1996-08-16
CA2048347C (en) 2002-01-29
NZ239213A (en) 1993-08-26

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