PT98554A - Processo para a preparacao de desoxinucleosidos - Google Patents

Processo para a preparacao de desoxinucleosidos

Info

Publication number
PT98554A
PT98554A PT98554A PT9855491A PT98554A PT 98554 A PT98554 A PT 98554A PT 98554 A PT98554 A PT 98554A PT 9855491 A PT9855491 A PT 9855491A PT 98554 A PT98554 A PT 98554A
Authority
PT
Portugal
Prior art keywords
preparation
deoxinucleosidos
substituted
compound
anhydrothymidine
Prior art date
Application number
PT98554A
Other languages
English (en)
Other versions
PT98554B (pt
Inventor
Kenneth E Green
John L Considine Jr
Joseph D Antuono Iii
Thurairajah Padmanathan
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of PT98554A publication Critical patent/PT98554A/pt
Publication of PT98554B publication Critical patent/PT98554B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
PT98554A 1990-08-06 1991-08-02 Processo para a preparacao de desoxinucleosidos PT98554B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US56359690A 1990-08-06 1990-08-06

Publications (2)

Publication Number Publication Date
PT98554A true PT98554A (pt) 1992-06-30
PT98554B PT98554B (pt) 1999-01-29

Family

ID=24251148

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98554A PT98554B (pt) 1990-08-06 1991-08-02 Processo para a preparacao de desoxinucleosidos

Country Status (21)

Country Link
EP (1) EP0470355B1 (pt)
JP (1) JP3026861B2 (pt)
KR (1) KR0173319B1 (pt)
CN (1) CN1031343C (pt)
AT (1) ATE138927T1 (pt)
AU (1) AU649698B2 (pt)
CA (1) CA2048347C (pt)
CZ (1) CZ283988B6 (pt)
DE (1) DE69119994T2 (pt)
DK (1) DK0470355T3 (pt)
ES (1) ES2088443T3 (pt)
FI (1) FI102375B (pt)
GR (1) GR3020946T3 (pt)
HU (1) HU209310B (pt)
IE (1) IE912762A1 (pt)
IL (1) IL98685A (pt)
NZ (1) NZ239213A (pt)
PL (1) PL166101B1 (pt)
PT (1) PT98554B (pt)
SK (1) SK278598B6 (pt)
ZA (1) ZA916156B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL100480A0 (en) * 1991-01-15 1992-09-06 American Cyanamid Co Process for the preparation of 3'-fluoropyrimidine nucleosides
GB9309787D0 (en) * 1993-05-12 1993-06-23 Rhone Poulenc Chemicals Purification of fluoronucleosides
GB9309795D0 (en) * 1993-05-12 1993-06-23 Rhone Poulenc Chemicals Preparation of flouro-compounds
DE69412090T2 (de) * 1993-05-12 1999-01-07 Rhodia Ltd Herstellung von fluoro-nukleosiden und dafür geeignete zwischenprodukte
JP3677790B2 (ja) * 1993-08-04 2005-08-03 味の素株式会社 ヌクレオシド誘導体とその製造方法
GB0608876D0 (en) 2006-05-05 2006-06-14 Medivir Ab Combination therapy

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3775397A (en) * 1969-11-12 1973-11-27 Akad Wissenschaften Ddr Novel cytostatic 2',3'-dideoxy-3'-fluoropyrimidine-nucleosides
SE464168B (sv) * 1989-07-19 1991-03-18 Bo Fredrik Oeberg Antiviral komposition bestaaende av en 3'-fluoro-2',3'-dideoxynukleosidfoerening och en 2',3'-dideoxynukleosidfoerening (exempelvis azt)

Also Published As

Publication number Publication date
DK0470355T3 (da) 1996-07-15
DE69119994T2 (de) 1997-01-23
GR3020946T3 (en) 1996-12-31
AU8163591A (en) 1992-02-13
FI913722A0 (fi) 1991-08-05
SK278598B6 (en) 1997-11-05
CS242991A3 (en) 1992-02-19
EP0470355B1 (en) 1996-06-05
KR0173319B1 (ko) 1999-02-18
CA2048347A1 (en) 1992-02-07
HU912601D0 (en) 1992-01-28
CA2048347C (en) 2002-01-29
JP3026861B2 (ja) 2000-03-27
IL98685A (en) 1996-08-04
CN1058969A (zh) 1992-02-26
PL291335A1 (en) 1992-08-24
HUT58756A (en) 1992-03-30
NZ239213A (en) 1993-08-26
CZ283988B6 (cs) 1998-07-15
DE69119994D1 (de) 1996-07-11
IE912762A1 (en) 1992-02-12
ES2088443T3 (es) 1996-08-16
CN1031343C (zh) 1996-03-20
IL98685A0 (en) 1992-07-15
AU649698B2 (en) 1994-06-02
ATE138927T1 (de) 1996-06-15
KR920004405A (ko) 1992-03-27
PL166101B1 (pl) 1995-03-31
JPH04253993A (ja) 1992-09-09
FI102375B1 (fi) 1998-11-30
HU209310B (en) 1994-04-28
FI102375B (fi) 1998-11-30
ZA916156B (en) 1992-04-29
EP0470355A1 (en) 1992-02-12
PT98554B (pt) 1999-01-29
FI913722A (fi) 1992-02-07

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19920219

FG3A Patent granted, date of granting

Effective date: 19981015

PD3A Change of proprietorship

Free format text: WYETH HOLDINGS CORPORATION US

Effective date: 20031117

TE3A Change of address (patent)

Free format text: AMERICAN CYANAMID COMPANY US

Effective date: 20040219

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: MAXIMUM VALIDITY LIMIT REACHED

Effective date: 20131015