DK0457318T3 - Alfa-Oxopyrrolo(2,3-b)indoleddikkesyrer, estere, salte og beslægtede analoge, en fremgangsmåde til deres fremstilling samt deres anvendelse som lægemidler - Google Patents

Alfa-Oxopyrrolo(2,3-b)indoleddikkesyrer, estere, salte og beslægtede analoge, en fremgangsmåde til deres fremstilling samt deres anvendelse som lægemidler

Info

Publication number
DK0457318T3
DK0457318T3 DK91107942.4T DK91107942T DK0457318T3 DK 0457318 T3 DK0457318 T3 DK 0457318T3 DK 91107942 T DK91107942 T DK 91107942T DK 0457318 T3 DK0457318 T3 DK 0457318T3
Authority
DK
Denmark
Prior art keywords
oxopyrrolo
pharmaceuticals
alpha
esters
salts
Prior art date
Application number
DK91107942.4T
Other languages
Danish (da)
English (en)
Inventor
Denise M Flanagan
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Application granted granted Critical
Publication of DK0457318T3 publication Critical patent/DK0457318T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
DK91107942.4T 1990-05-17 1991-05-16 Alfa-Oxopyrrolo(2,3-b)indoleddikkesyrer, estere, salte og beslægtede analoge, en fremgangsmåde til deres fremstilling samt deres anvendelse som lægemidler DK0457318T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52462790A 1990-05-17 1990-05-17

Publications (1)

Publication Number Publication Date
DK0457318T3 true DK0457318T3 (da) 1996-12-09

Family

ID=24090019

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91107942.4T DK0457318T3 (da) 1990-05-17 1991-05-16 Alfa-Oxopyrrolo(2,3-b)indoleddikkesyrer, estere, salte og beslægtede analoge, en fremgangsmåde til deres fremstilling samt deres anvendelse som lægemidler

Country Status (22)

Country Link
EP (1) EP0457318B1 (en16)
JP (1) JPH0826024B2 (en16)
KR (2) KR100215615B1 (en16)
AR (1) AR247888A1 (en16)
AT (1) ATE141273T1 (en16)
AU (1) AU634380B2 (en16)
CA (1) CA2042737A1 (en16)
CZ (1) CZ280922B6 (en16)
DE (1) DE69121299T2 (en16)
DK (1) DK0457318T3 (en16)
ES (1) ES2094768T3 (en16)
FI (1) FI96689C (en16)
GR (1) GR3021043T3 (en16)
HU (1) HU210179B (en16)
IE (1) IE76318B1 (en16)
IL (1) IL98162A (en16)
MX (2) MX25777A (en16)
NO (1) NO177710C (en16)
NZ (2) NZ238151A (en16)
PL (1) PL290273A1 (en16)
PT (1) PT97688B (en16)
ZA (1) ZA913711B (en16)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4983616A (en) * 1990-02-01 1991-01-08 Hoechst-Roussel Pharmaceuticals Inc. Hexahydropyrrolo(2,3-B)indole carbamates, ureas, amides and related compounds
AU634654B2 (en) * 1990-05-11 1993-02-25 Hoechst-Roussel Pharmaceuticals Incorporated Pyrrolo(2,3-b)indole-ketones and analogs, a process for their preparation and their use as medicaments
AU649953B2 (en) * 1990-06-27 1994-06-09 Hoechst-Roussel Pharmaceuticals Incorporated Tetrahydroisoquinolinylcarbamates of 1,2,3,3A,8,8A-hexahydro-1,3A,8-trimethylpyrrolo(2,3-B)indole
US7229986B2 (en) 2000-05-16 2007-06-12 Takeda Pharmaceutical Company Ltd. Melanin-concentrating hormone antagonist
WO2010027334A1 (en) 2008-09-03 2010-03-11 Nanyang Technological University Novel tricyclic chiral compounds and their use in asymmetric catalysis

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1199076B (it) * 1984-03-01 1988-12-30 Consiglio Nazionale Ricerche Derivati della fisostigmina con proprieta'di inibizione della aceticolinesterasi e relativo procedimento di produzione
US4791107A (en) * 1986-07-16 1988-12-13 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use
US4971992A (en) * 1989-03-27 1990-11-20 Hoechst-Roussel Pharmaceuticals Inc. Carbonate derivatives of eseroline

Also Published As

Publication number Publication date
NO911892L (no) 1991-11-18
NZ260210A (en) 1996-02-27
NZ238151A (en16) 1996-02-27
HU210179B (en) 1995-02-28
IL98162A0 (en) 1992-06-21
JPH04226989A (ja) 1992-08-17
KR100215615B1 (ko) 1999-08-16
KR100227715B1 (ko) 2000-03-15
EP0457318B1 (en) 1996-08-14
IE911678A1 (en) 1991-11-20
NO177710B (no) 1995-07-31
AU7618291A (en) 1991-11-21
NO911892D0 (no) 1991-05-15
PT97688A (pt) 1992-02-28
ZA913711B (en) 1992-01-29
FI96689B (fi) 1996-04-30
DE69121299T2 (de) 1997-02-06
MX25816A (es) 1993-11-01
DE69121299D1 (de) 1996-09-19
CS142991A3 (en) 1992-01-15
FI912363A0 (fi) 1991-05-15
IE76318B1 (en) 1997-10-22
FI912363L (fi) 1991-11-18
AU634380B2 (en) 1993-02-18
KR910020014A (ko) 1991-12-19
GR3021043T3 (en) 1996-12-31
HUT61310A (en) 1992-12-28
ATE141273T1 (de) 1996-08-15
JPH0826024B2 (ja) 1996-03-13
NO177710C (no) 1995-11-08
PL290273A1 (en) 1992-07-27
CA2042737A1 (en) 1991-11-18
FI96689C (fi) 1996-08-12
CZ280922B6 (cs) 1996-05-15
EP0457318A1 (en) 1991-11-21
ES2094768T3 (es) 1997-02-01
MX25777A (es) 1993-10-01
AR247888A1 (es) 1995-04-28
IL98162A (en) 1994-12-29
HU911658D0 (en) 1991-11-28
PT97688B (pt) 1998-08-31

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