DK0436426T3 - Fremgangsmåde til fremstilling af 1-phenylimidazolin-2,5-dionderivater - Google Patents

Fremgangsmåde til fremstilling af 1-phenylimidazolin-2,5-dionderivater

Info

Publication number
DK0436426T3
DK0436426T3 DK90403725.6T DK90403725T DK0436426T3 DK 0436426 T3 DK0436426 T3 DK 0436426T3 DK 90403725 T DK90403725 T DK 90403725T DK 0436426 T3 DK0436426 T3 DK 0436426T3
Authority
DK
Denmark
Prior art keywords
preparation
formula
image
phenylimidazoline
denote
Prior art date
Application number
DK90403725.6T
Other languages
Danish (da)
English (en)
Inventor
Patrick Seuron
Daniel Varraillon
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Application granted granted Critical
Publication of DK0436426T3 publication Critical patent/DK0436426T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/74—Two oxygen atoms, e.g. hydantoin with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to other ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Reinforced Plastic Materials (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
DK90403725.6T 1989-12-22 1990-12-21 Fremgangsmåde til fremstilling af 1-phenylimidazolin-2,5-dionderivater DK0436426T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8917046A FR2656302B1 (fr) 1989-12-22 1989-12-22 Nouveau procede de preparation de l'anandron et derives de l'anandron.

Publications (1)

Publication Number Publication Date
DK0436426T3 true DK0436426T3 (da) 1994-07-04

Family

ID=9388859

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90403725.6T DK0436426T3 (da) 1989-12-22 1990-12-21 Fremgangsmåde til fremstilling af 1-phenylimidazolin-2,5-dionderivater

Country Status (24)

Country Link
US (1) US5166358A (sk)
EP (1) EP0436426B1 (sk)
JP (1) JP2836041B2 (sk)
KR (1) KR0173307B1 (sk)
CN (1) CN1048011C (sk)
AT (1) ATE107289T1 (sk)
AU (1) AU628699B2 (sk)
CA (1) CA2032988C (sk)
CZ (1) CZ281655B6 (sk)
DE (1) DE69009964T2 (sk)
DK (1) DK0436426T3 (sk)
ES (1) ES2055382T3 (sk)
FI (1) FI103203B (sk)
FR (1) FR2656302B1 (sk)
HU (1) HU207301B (sk)
IE (1) IE65510B1 (sk)
IL (1) IL96696A (sk)
NZ (1) NZ236621A (sk)
PL (1) PL164694B1 (sk)
PT (1) PT96313B (sk)
RU (1) RU1836356C (sk)
SK (1) SK278447B6 (sk)
UA (1) UA27220C2 (sk)
ZA (1) ZA909648B (sk)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2693461B1 (fr) * 1992-07-08 1994-09-02 Roussel Uclaf Nouvelles phénylimidazolidines substituées, leur procédé de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant.
US5411981A (en) * 1991-01-09 1995-05-02 Roussel Uclaf Phenylimidazolidines having antiandrogenic activity
FR2694290B1 (fr) * 1992-07-08 1994-09-02 Roussel Uclaf Nouvelles phénylimidazolidines éventuellement substituées, leur procédé de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant.
US5656651A (en) * 1995-06-16 1997-08-12 Biophysica Inc. Androgenic directed compositions
FR2741346B1 (fr) * 1995-11-16 1997-12-19 Roussel Uclaf Nouveau procede de preparation de derives phenylimidazolidine
FR2741342B1 (fr) * 1995-11-22 1998-02-06 Roussel Uclaf Nouvelles phenylimidazolidines fluorees ou hydroxylees, procede, intermediaires de preparation, application comme medicaments, nouvelle utilisation et compositions pharmaceutiques
JPH1072446A (ja) * 1996-06-24 1998-03-17 Sumitomo Chem Co Ltd １−置換−ヒダントイン類の製造法
CA2413417A1 (en) * 2000-06-28 2002-01-03 Bristol-Myers Squibb Company Selective androgen receptor modulators and methods for their identification, design and use
EP1854798A3 (en) 2000-09-19 2007-11-28 Bristol-Myers Squibb Company Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US20040087548A1 (en) 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
CA2550447A1 (en) * 2003-12-19 2005-07-07 The Regents Of The University Of California Methods and materials for assessing prostate cancer therapies
NZ550102A (en) * 2004-02-24 2010-10-29 Univ California Methods and materials for assessing prostate cancer therapies and compounds (thiohydantoine derivatives)
US7709517B2 (en) 2005-05-13 2010-05-04 The Regents Of The University Of California Diarylhydantoin compounds
PT2656841T (pt) 2006-03-27 2016-09-28 Univ California Modulador do recetor de androgénios para o tratamento de cancro da próstata e doenças associadas ao recetor de androgénios
KR101600230B1 (ko) 2006-03-29 2016-03-04 더 리전트 오브 더 유니버시티 오브 캘리포니아 디아릴티오히단토인 화합물
EP2220050A2 (en) 2007-10-26 2010-08-25 The Regents Of The University Of California Diarylhydantoin compounds as androgen receptor modulators
ES2668380T3 (es) 2010-02-16 2018-05-17 Aragon Pharmaceuticals, Inc. Moduladores de receptores de andrógenos y sus usos
SI3305285T1 (sl) 2012-09-26 2021-03-31 Aragon Pharmaceuticals, Inc. Anti-androgeni za zdravljenje proti kastraciji odpornega ne-metastatskega raka
JOP20200097A1 (ar) 2013-01-15 2017-06-16 Aragon Pharmaceuticals Inc معدل مستقبل أندروجين واستخداماته
TWI726969B (zh) 2016-01-11 2021-05-11 比利時商健生藥品公司 用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物
JOP20200076A1 (ar) 2017-10-16 2020-04-30 Aragon Pharmaceuticals Inc مضادات أندروجين لعلاج سرطان البروستاتا غير النقيلي المقاوم للاستئصال

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH166004A (de) * 1934-06-06 1933-12-15 Chem Fab Vormals Sandoz Verfahren zur Darstellung eines Derivates des 5,5-Phenyläthylhydantoins.
US2490813A (en) * 1944-11-29 1949-12-13 Standard Oil Co Continuous process for making aryl amines
US2759002A (en) * 1954-03-24 1956-08-14 Abbott Lab 3-benzyl hydantoin and process
US3134663A (en) * 1957-07-23 1964-05-26 Geigy Chem Corp Herbicidal composition and method employing hydantoins
US3914311A (en) * 1973-06-15 1975-10-21 Du Pont Preparation of aromatic secondary and tertiary amines using a nickel complex catalyst
DE2414613A1 (de) * 1974-03-26 1975-10-16 Bayer Ag 1-aryl-5-alkyliden-2,4-dioxo-imidazolidine
FR2329276A1 (fr) * 1975-10-29 1977-05-27 Roussel Uclaf Nouvelles imidazolidines substituees, procede de preparation, application comme medicament et compositions les renfermant
IL55774A (en) * 1977-10-28 1982-04-30 Sparamedica Ag Pharmaceutical compositions containing urea derivatives,certain such novel derivatives and their manufacture
GB1598166A (en) * 1978-05-23 1981-09-16 Lilly Industries Ltd 3,5-disubstituted hydantoin derivatives
US4764625A (en) * 1980-12-12 1988-08-16 Xerox Corporation Process for preparing arylamines
EP0091596B1 (de) * 1982-04-08 1991-09-11 Shell Internationale Researchmaatschappij B.V. Neue Hydantoine, ihre Herstellung und Verwendung

Also Published As

Publication number Publication date
KR910011799A (ko) 1991-08-07
IE65510B1 (en) 1995-11-01
PL288365A1 (en) 1991-09-09
CN1052666A (zh) 1991-07-03
CA2032988C (fr) 2003-04-29
SK656790A3 (en) 1997-06-04
ES2055382T3 (es) 1994-08-16
RU1836356C (ru) 1993-08-23
DE69009964D1 (de) 1994-07-21
FI103203B1 (fi) 1999-05-14
HU207301B (en) 1993-03-29
CZ281655B6 (cs) 1996-12-11
CA2032988A1 (fr) 1991-06-23
FR2656302A1 (fr) 1991-06-28
HU908416D0 (en) 1991-07-29
EP0436426A1 (fr) 1991-07-10
FI906366A0 (fi) 1990-12-21
PT96313A (pt) 1991-09-30
SK278447B6 (en) 1997-06-04
KR0173307B1 (ko) 1999-02-01
FR2656302B1 (fr) 1992-05-07
NZ236621A (en) 1992-04-28
IL96696A0 (en) 1991-09-16
US5166358A (en) 1992-11-24
IL96696A (en) 1995-08-31
JP2836041B2 (ja) 1998-12-14
CN1048011C (zh) 2000-01-05
EP0436426B1 (fr) 1994-06-15
PL164694B1 (pl) 1994-09-30
AU6826590A (en) 1991-06-27
UA27220C2 (uk) 2000-08-15
ATE107289T1 (de) 1994-07-15
CZ656790A3 (en) 1996-08-14
IE904142A1 (en) 1991-07-03
PT96313B (pt) 1998-06-30
DE69009964T2 (de) 1994-10-13
FI103203B (fi) 1999-05-14
AU628699B2 (en) 1992-09-17
JPH04103573A (ja) 1992-04-06
ZA909648B (en) 1992-02-26
FI906366A (fi) 1991-06-23

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