DK0411941T3 - Fremgangsmåde til oprensning af aminomethylenphosphonsyrer - Google Patents

Fremgangsmåde til oprensning af aminomethylenphosphonsyrer

Info

Publication number
DK0411941T3
DK0411941T3 DK90308524.9T DK90308524T DK0411941T3 DK 0411941 T3 DK0411941 T3 DK 0411941T3 DK 90308524 T DK90308524 T DK 90308524T DK 0411941 T3 DK0411941 T3 DK 0411941T3
Authority
DK
Denmark
Prior art keywords
purification
phosphonic acids
aminomethylene phosphonic
aminomethylene
acids
Prior art date
Application number
DK90308524.9T
Other languages
Danish (da)
English (en)
Inventor
Joseph R Galich
Tipton T Masterson
Jaime Simon
Original Assignee
Dow Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Chemical Co filed Critical Dow Chemical Co
Application granted granted Critical
Publication of DK0411941T3 publication Critical patent/DK0411941T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/44—Amides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6524—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/025—Purification; Separation; Stabilisation; Desodorisation of organo-phosphorus compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
    • C07F9/3817—Acids containing the structure (RX)2P(=X)-alk-N...P (X = O, S, Se)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
DK90308524.9T 1989-08-04 1990-08-02 Fremgangsmåde til oprensning af aminomethylenphosphonsyrer DK0411941T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/389,441 US4937333A (en) 1989-08-04 1989-08-04 Method for purifying aminomethylenephosphonic acids for pharmaceutical use

Publications (1)

Publication Number Publication Date
DK0411941T3 true DK0411941T3 (da) 1996-11-11

Family

ID=23538280

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90308524.9T DK0411941T3 (da) 1989-08-04 1990-08-02 Fremgangsmåde til oprensning af aminomethylenphosphonsyrer

Country Status (38)

Country Link
US (1) US4937333A (no)
EP (1) EP0411941B1 (no)
JP (1) JP2922263B2 (no)
KR (2) KR0178779B1 (no)
CN (2) CN1024196C (no)
AP (1) AP163A (no)
AT (1) ATE140459T1 (no)
AU (1) AU634267B2 (no)
BG (1) BG60519B1 (no)
BR (2) BR9003694A (no)
CA (1) CA2020950C (no)
CZ (1) CZ290556B6 (no)
DD (1) DD297414A5 (no)
DE (1) DE69027818T2 (no)
DK (1) DK0411941T3 (no)
DZ (1) DZ1436A1 (no)
EG (1) EG19250A (no)
ES (1) ES2090105T3 (no)
FI (1) FI105033B (no)
GR (1) GR3020932T3 (no)
HK (1) HK1007558A1 (no)
HU (1) HU205128B (no)
IE (1) IE902812A1 (no)
IL (3) IL110861A (no)
LV (1) LV10718B (no)
MA (1) MA21922A1 (no)
NO (2) NO178196C (no)
NZ (2) NZ247888A (no)
OA (1) OA09300A (no)
PH (1) PH26901A (no)
PL (2) PL166453B1 (no)
PT (1) PT94188B (no)
RO (1) RO105967B1 (no)
RU (1) RU1838321C (no)
SA (1) SA90110175B1 (no)
SK (1) SK379690A3 (no)
YU (1) YU47368B (no)
ZA (1) ZA905564B (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4937333A (en) * 1989-08-04 1990-06-26 The Dow Chemical Company Method for purifying aminomethylenephosphonic acids for pharmaceutical use
MC2260A1 (fr) * 1990-06-18 1993-04-26 Dow Chemical Co Formulations de produits radiopharmaceutiques,leur methode d'administration et leur procede de preparation
EP0494603A3 (en) * 1991-01-10 1993-10-20 Hoechst Ag Process for extractive separation of phospho- and sulphobetaines from acidic reaction solutions
US5410043A (en) * 1991-12-06 1995-04-25 Schering Aktiengesellschaft Process for the production of mono-N-substituted tetraaza macrocycles
US5320829A (en) * 1991-12-10 1994-06-14 The Dow Chemical Company Oral compositions for inhibiting plaque formation
DE4218744C2 (de) * 1992-06-04 1997-11-06 Schering Ag Verfahren zur Herstellung von N-ß-Hxdroxyalkyl-tri-N-carboxylalkyl-1,4,7,10-tetraazacyclododecan- und N-ß-Hydroxyalkyl-tri-N-carboxyalkyl-1,4,8,11-tetraazacyclotetradecan-Derivaten und deren Metallkomplexe
US5495042A (en) * 1993-11-04 1996-02-27 Cytogen Corporation Non-alkaline purification of aminophosphonic acids
EP1191948A2 (en) * 1999-06-11 2002-04-03 Neorx Corporation High dose radionuclide complexes for bone marrow suppression
US7094885B2 (en) * 1999-07-11 2006-08-22 Neorx Corporation Skeletal-targeted radiation to treat bone-associated pathologies
JP2003512331A (ja) * 1999-10-18 2003-04-02 ザ ダウ ケミカル カンパニー 骨障害治療用アミノアルキレンホスホネート
US6794371B1 (en) * 1999-10-18 2004-09-21 The Dow Chemical Company Aminoalkylenephosphonates for treatment of bone disorders
EP1390081A2 (en) * 2001-01-08 2004-02-25 Neorx Corporation Therapeutic and diagnostic compounds, compositions, and methods
AU2003296117A1 (en) * 2002-12-27 2004-07-29 Sumitomo Chemical Company, Limited Method and apparatus for crystallization
EP1778699A4 (en) * 2004-08-10 2009-02-25 Dow Global Technologies Inc TARGETING OF CHELANTS AND CHELATES
CN101381377B (zh) * 2008-10-23 2011-05-04 山东省泰和水处理有限公司 一种适用于电子级固体己二胺四亚甲基膦酸的制备工艺
JP5581832B2 (ja) * 2010-06-11 2014-09-03 三菱瓦斯化学株式会社 高純度アミノメチレンホスホン酸の製造方法
CN103724373A (zh) * 2014-01-02 2014-04-16 山东省泰和水处理有限公司 多聚甲醛生产氨基三亚甲基膦酸的方法
US10590153B2 (en) 2014-06-02 2020-03-17 Zschimmer & Schwarz Mohsdorf GmbH & Co. KG Process for producing crystalline DTPMP
DE102014210378B4 (de) 2014-06-02 2018-10-04 Zschimmer & Schwarz Mohsdorf GmbH &Co.KG. Verfahren zur Herstellung hochreiner Aminoalkylenphosphonsäuren
CN113263580A (zh) * 2021-04-23 2021-08-17 广东工业大学 一种多功能床头柜制造设备

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2599807A (en) * 1950-06-01 1952-06-10 Frederick C Bersworth Alkylene polyamine methylene phosphonic acids
NL285361A (no) * 1961-11-13 1900-01-01
US3738937A (en) * 1970-05-08 1973-06-12 Textilana Corp Polyalkylene polyamino polykis methylene phosphonic acids and salts thereof and methods for producing same
NL7903500A (nl) * 1979-05-04 1980-11-06 Philips Nv Verbrandingsflitslamp en flitsinrichting voorzien van verscheidene verbrandingsflitslampen.
JPS5775990A (en) * 1980-10-27 1982-05-12 Mitsubishi Gas Chem Co Inc Preparation of n,n,n',n'-tetra(phosphonomethyl) diaminoalkane
EP0225409A1 (en) * 1985-12-02 1987-06-16 The Dow Chemical Company Organic amine phosphonic acid complexes for the treatment of calcific tumors
US4937333A (en) * 1989-08-04 1990-06-26 The Dow Chemical Company Method for purifying aminomethylenephosphonic acids for pharmaceutical use
GB8903023D0 (en) * 1989-02-10 1989-03-30 Parker David Chemical compounds
DE3911816A1 (de) * 1989-04-11 1990-10-25 Hoechst Ag Substituierte 1,4,7,10-tetraazacyclotridecane, verfahren zu deren herstellung sowie verwendung derselben zur markierung von substanzen mit radionukliden

Also Published As

Publication number Publication date
BR1101174A (pt) 2000-08-08
DE69027818D1 (de) 1996-08-22
PT94188B (pt) 1996-12-31
NZ247888A (en) 1994-07-26
US4937333A (en) 1990-06-26
EP0411941B1 (en) 1996-07-17
FI903864A0 (fi) 1990-08-03
IL95094A (en) 1995-05-26
CZ379690A3 (cs) 2000-08-16
IL95094A0 (en) 1991-06-10
SK279107B6 (sk) 1998-06-03
AP163A (en) 1992-01-11
HU904890D0 (en) 1991-01-28
CN1049351A (zh) 1991-02-20
JPH0366697A (ja) 1991-03-22
DD297414A5 (de) 1992-01-09
SK379690A3 (en) 1998-06-03
NO178196C (no) 1996-02-07
LV10718B (en) 1996-04-20
IL110861A0 (en) 1994-11-28
PL164908B1 (pl) 1994-10-31
PL166453B1 (pl) 1995-05-31
KR0178779B1 (ko) 1999-05-15
HUT54698A (en) 1991-03-28
SA90110175B1 (ar) 2004-03-09
CN1031191C (zh) 1996-03-06
BR9003694A (pt) 1991-09-03
KR910004642A (ko) 1991-03-29
AP9000202A0 (en) 1990-10-31
CN1024196C (zh) 1994-04-13
DE69027818T2 (de) 1996-11-21
IL110861A (en) 1999-07-14
YU47368B (sh) 1995-01-31
EG19250A (en) 1994-09-29
NZ234464A (en) 1994-06-27
OA09300A (en) 1992-09-15
HK1007558A1 (en) 2003-07-10
HU205128B (en) 1992-03-30
NO903419L (no) 1991-02-05
PH26901A (en) 1992-12-03
ZA905564B (en) 1992-03-25
JP2922263B2 (ja) 1999-07-19
FI105033B (fi) 2000-05-31
NO178196B (no) 1995-10-30
EP0411941A2 (en) 1991-02-06
PT94188A (pt) 1991-04-18
ES2090105T3 (es) 1996-10-16
CZ290556B6 (cs) 2002-08-14
CA2020950A1 (en) 1991-02-05
CN1091744A (zh) 1994-09-07
LV10718A (lv) 1995-06-20
BG92627A (bg) 1993-12-24
RO105967B1 (ro) 1993-01-30
KR0178877B1 (ko) 1999-05-15
EP0411941A3 (en) 1992-04-15
NO903419D0 (no) 1990-08-03
RU1838321C (ru) 1993-08-30
YU145390A (sh) 1992-09-07
BG60519B1 (bg) 1995-07-28
ATE140459T1 (de) 1996-08-15
GR3020932T3 (en) 1996-12-31
NO970653D0 (no) 1997-02-12
MA21922A1 (fr) 1991-04-01
IE902812A1 (en) 1991-02-27
NO970653L (no) 1991-02-05
DZ1436A1 (fr) 2004-09-13
PL286349A1 (en) 1991-05-20
AU6023790A (en) 1991-02-07
CA2020950C (en) 2000-04-11
AU634267B2 (en) 1993-02-18

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