DK0405820T3 - Fremgangsmåde til fremstilling af isepamicin - Google Patents

Fremgangsmåde til fremstilling af isepamicin

Info

Publication number
DK0405820T3
DK0405820T3 DK90306657.9T DK90306657T DK0405820T3 DK 0405820 T3 DK0405820 T3 DK 0405820T3 DK 90306657 T DK90306657 T DK 90306657T DK 0405820 T3 DK0405820 T3 DK 0405820T3
Authority
DK
Denmark
Prior art keywords
isoserine
isepamicin
producing
compounds
diformyl
Prior art date
Application number
DK90306657.9T
Other languages
Danish (da)
English (en)
Inventor
Chou-Hong Tann
Tiruvettipuram K Thiruvengadam
John Sze-Hung Chiu
Cesar Colon
Michael D Green
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of DK0405820T3 publication Critical patent/DK0405820T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C07H15/236—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2 a saccharide radical being substituted by an alkylamino radical in position 3 and by two substituents different from hydrogen in position 4, e.g. gentamicin complex, sisomicin, verdamycin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
DK90306657.9T 1989-06-21 1990-06-19 Fremgangsmåde til fremstilling af isepamicin DK0405820T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36957889A 1989-06-21 1989-06-21

Publications (1)

Publication Number Publication Date
DK0405820T3 true DK0405820T3 (da) 1994-05-16

Family

ID=23456036

Family Applications (2)

Application Number Title Priority Date Filing Date
DK93102033.3T DK0547031T3 (da) 1989-06-21 1990-06-19 N-beskyttede (S)-isoserinforbindelser
DK90306657.9T DK0405820T3 (da) 1989-06-21 1990-06-19 Fremgangsmåde til fremstilling af isepamicin

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK93102033.3T DK0547031T3 (da) 1989-06-21 1990-06-19 N-beskyttede (S)-isoserinforbindelser

Country Status (16)

Country Link
EP (3) EP0478707A1 (de)
JP (2) JPH0692433B2 (de)
KR (1) KR940003496B1 (de)
AT (2) ATE152094T1 (de)
AU (1) AU629960B2 (de)
CA (2) CA2325082A1 (de)
DE (2) DE69030590T2 (de)
DK (2) DK0547031T3 (de)
ES (2) ES2063274T3 (de)
FI (1) FI96955C (de)
GR (1) GR3023942T3 (de)
HK (2) HK185096A (de)
HU (1) HU207338B (de)
NO (1) NO177349C (de)
RU (1) RU2120444C1 (de)
WO (1) WO1990015810A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100927626B1 (ko) * 2002-09-18 2009-11-20 쯔지앙 하이썬 파머슈티컬 컴퍼니, 리미티드 이세파마이신의 제조 방법
CN101928310B (zh) * 2010-03-26 2012-09-05 常州方圆制药有限公司 3,2’,6’-三-N-乙酰基庆大霉素C1a的制备方法
CN102190690B (zh) * 2011-04-01 2015-01-21 福州博立医药科技有限公司 一种简便且高收率阿贝卡星合成方法
CN105524129B (zh) * 2015-12-25 2018-06-26 无锡济民可信山禾药业股份有限公司 一种硫酸依替米星的制备方法
RU2659032C1 (ru) * 2017-04-26 2018-06-27 Федеральное государственное бюджетное образовательное учреждение высшего образования "Удмуртский государственный университет" Способ модификации гентамицина сополимером винилпирролидона с диацеталем акролеина
CN108586313B (zh) * 2018-03-31 2019-12-27 海正药业南通有限公司 一种新型合成n-取代苯酐-(s)-异丝氨酸的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4136254A (en) * 1976-06-17 1979-01-23 Schering Corporation Process of selectively blocking amino functions in aminoglycosides using transition metal salts and intermediates used thereby
IE48972B1 (en) * 1978-11-11 1985-06-26 Microbial Chem Res Found The production of a selectively protected n-acylated derivative of an aminoglycosidic antibiotic
EP0156771A3 (de) * 1984-03-29 1986-03-19 Biochemie Gesellschaft M.B.H. Cephalosporinverbindungen

Also Published As

Publication number Publication date
JPH04502474A (ja) 1992-05-07
ES2100380T3 (es) 1997-06-16
EP0405820B1 (de) 1994-04-13
ES2063274T3 (es) 1995-01-01
DE69030590T2 (de) 1997-08-07
HU207338B (en) 1993-03-29
NO915071L (no) 1991-12-20
DE69008052D1 (de) 1994-05-19
EP0547031A1 (de) 1993-06-16
FI96955B (fi) 1996-06-14
KR920701226A (ko) 1992-08-11
ATE152094T1 (de) 1997-05-15
AU5946390A (en) 1991-01-08
JP2500059B2 (ja) 1996-05-29
FI915953A0 (fi) 1991-12-18
RU2120444C1 (ru) 1998-10-20
WO1990015810A2 (en) 1990-12-27
DE69008052T2 (de) 1994-07-28
CA2062788A1 (en) 1990-12-22
KR940003496B1 (ko) 1994-04-23
EP0405820A3 (en) 1991-04-10
HK1000153A1 (en) 1998-01-02
AU629960B2 (en) 1992-10-15
GR3023942T3 (en) 1997-09-30
HUT59934A (en) 1992-07-28
WO1990015810A3 (en) 1991-04-04
JPH07133267A (ja) 1995-05-23
NO177349C (no) 1995-08-30
CA2325082A1 (en) 1990-12-22
CA2062788C (en) 2001-10-23
FI96955C (fi) 1996-09-25
JPH0692433B2 (ja) 1994-11-16
DE69030590D1 (de) 1997-05-28
HU906641D0 (en) 1992-03-30
NO177349B (no) 1995-05-22
DK0547031T3 (da) 1997-05-20
ATE104310T1 (de) 1994-04-15
NO915071D0 (no) 1991-12-20
EP0547031B1 (de) 1997-04-23
EP0405820A2 (de) 1991-01-02
HK185096A (en) 1996-10-11
EP0478707A1 (de) 1992-04-08

Similar Documents

Publication Publication Date Title
ES2083392T3 (es) Sustancia pf 1022, procedimiento para su preparacion y composicion antihelmintica que contiene esta sustancia.
AU2640388A (en) Process for producing styrene-based polymers and catalyst for use therein
DK0405820T3 (da) Fremgangsmåde til fremstilling af isepamicin
JPS5334984A (en) Immobilization of enzyme by light irradiation
DE3773077D1 (de) Immunotoxine, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.
DE69312566T2 (de) Verfahren zur Herstellung von Alkylpolyglukosiden
DE59104936D1 (de) Verfahren zur Herstellung von Allantoin.
DE3262622D1 (en) Preparation of a glutaraldehyde precursor
DE69102428D1 (de) Copolymere aus dioxolanen und maleinsäureanhydrid.
JPS546029A (en) Anaerobic adhesive composition
DK0711764T3 (da) Fremgangsmåde til fremstilling af L-ascorbinsyre
DK0399748T3 (da) Fremgangsmåde til fremstilling af 2-oxindol-1-carboxamider
ATE86962T1 (de) Verfahren zur herstellung 1,4-disubstituierter 2- butene.
ES2169190T3 (es) Procedimiento para la preparacion de compuestos de funcionalidad carbamato o urea.
JPS53142594A (en) Immobilization of enzyme or microbial cells
JPS51138650A (en) Process for preparing optically active trans-cyclopentene-3,5,-diolmon oester
DK649587A (da) Fremgangsmaade til fremstilling af en polymer
JPS5290694A (en) Preparation of protoporphyrine 1x
ES2061602T3 (es) Polimeros acrilicos imidizados y procedimiento para su preparacion.
JPS52123479A (en) Novel unaerobically curing composition
JPS52117650A (en) Wavelength conversion film
JPS535121A (en) Preparation of cis-1.2-epoxypropylphosphonic acids
JPS52110889A (en) Immobilization of yeast or microbial cells
JPS53108251A (en) Encoding-decoding device
JPS5422176A (en) Manufacture of semiconductor device