DET0008241MA - - Google Patents

Info

Publication number

DET0008241MA

DET0008241MA DET0008241MA DE T0008241M A DET0008241M A DE T0008241MA DE T0008241M A DET0008241M A DE T0008241MA

Authority

DE

Germany

Prior art keywords

fibrin

fresh blood

complexes

chlorophyll

complex

Prior art date

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

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• BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 claims description 7
• 239000008280 blood Substances 0.000 claims description 7
• 210000004369 blood Anatomy 0.000 claims description 7
• 150000001875 compounds Chemical class 0.000 claims description 7
• 235000019804 chlorophyll Nutrition 0.000 claims description 6
• 229930002875 chlorophyll Natural products 0.000 claims description 6
• ATNHDLDRLWWWCB-AENOIHSZSA-M chlorophyll a Chemical compound C1([C@@H](C(=O)OC)C(=O)C2=C3C)=C2N2C3=CC(C(CC)=C3C)=[N+]4C3=CC3=C(C=C)C(C)=C5N3[Mg-2]42[N+]2=C1[C@@H](CCC(=O)OC\C=C(/C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)[C@H](C)C2=C5 ATNHDLDRLWWWCB-AENOIHSZSA-M 0.000 claims description 6
• 229910052751 metal Inorganic materials 0.000 claims description 6
• 239000002184 metal Substances 0.000 claims description 6
• 102000009123 Fibrin Human genes 0.000 claims description 4
• 108010073385 Fibrin Proteins 0.000 claims description 4
• 229950003499 fibrin Drugs 0.000 claims description 4
• XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 4
• 238000000034 method Methods 0.000 claims description 3
• 150000004032 porphyrins Chemical class 0.000 claims description 3
• ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims description 2
• 239000000460 chlorine Substances 0.000 claims description 2
• 229910052801 chlorine Inorganic materials 0.000 claims description 2
• -1 copper complex sodium salt Chemical class 0.000 claims description 2
• 238000004519 manufacturing process Methods 0.000 claims description 2
• SURLGNKAQXKNSP-DBLYXWCISA-N chlorin Chemical compound C\1=C/2\N/C(=C\C3=N/C(=C\C=4NC(/C=C\5/C=CC/1=N/5)=CC=4)/C=C3)/CC\2 SURLGNKAQXKNSP-DBLYXWCISA-N 0.000 claims 2
• 206010052428 Wound Diseases 0.000 claims 1
• 208000027418 Wounds and injury Diseases 0.000 claims 1
• 239000007795 chemical reaction product Substances 0.000 claims 1
• 230000015271 coagulation Effects 0.000 claims 1
• 238000005345 coagulation Methods 0.000 claims 1
• GPRXGEKBQVXWAQ-UHFFFAOYSA-L disodium;3-[18-(2-carboxylatoethyl)-8,13-bis(ethenyl)-3,7,12,17-tetramethyl-22,23-dihydroporphyrin-2-yl]propanoate Chemical compound [Na+].[Na+].N1C(C=C2C(=C(C)C(=CC=3C(C)=C(CCC([O-])=O)C(N=3)=C3)N2)C=C)=C(C)C(C=C)=C1C=C1C(C)=C(CCC([O-])=O)C3=N1 GPRXGEKBQVXWAQ-UHFFFAOYSA-L 0.000 claims 1
• 239000003814 drug Substances 0.000 claims 1
• 229940079593 drug Drugs 0.000 claims 1
• 230000029142 excretion Effects 0.000 claims 1
• 239000000049 pigment Substances 0.000 claims 1
• 230000035755 proliferation Effects 0.000 claims 1
• 239000011541 reaction mixture Substances 0.000 claims 1
• 150000003839 salts Chemical class 0.000 claims 1
• 230000000638 stimulation Effects 0.000 claims 1
• 238000003756 stirring Methods 0.000 claims 1
• 238000005406 washing Methods 0.000 claims 1
• 235000019805 chlorophyllin Nutrition 0.000 description 3
• 230000001476 alcoholic effect Effects 0.000 description 2
• 229940099898 chlorophyllin Drugs 0.000 description 2
• 239000000243 solution Substances 0.000 description 2
• 102000001554 Hemoglobins Human genes 0.000 description 1
• 108010054147 Hemoglobins Proteins 0.000 description 1
• 239000007864 aqueous solution Substances 0.000 description 1
• 239000001752 chlorophylls and chlorophyllins Substances 0.000 description 1
• HWDGVJUIHRPKFR-UHFFFAOYSA-I copper;trisodium;18-(2-carboxylatoethyl)-20-(carboxylatomethyl)-12-ethenyl-7-ethyl-3,8,13,17-tetramethyl-17,18-dihydroporphyrin-21,23-diide-2-carboxylate Chemical class [Na+].[Na+].[Na+].[Cu+2].N1=C(C(CC([O-])=O)=C2C(C(C)C(C=C3C(=C(C=C)C(=C4)[N-]3)C)=N2)CCC([O-])=O)C(=C([O-])[O-])C(C)=C1C=C1C(CC)=C(C)C4=N1 HWDGVJUIHRPKFR-UHFFFAOYSA-I 0.000 description 1
• 238000001914 filtration Methods 0.000 description 1
• 239000000843 powder Substances 0.000 description 1
• 210000002966 serum Anatomy 0.000 description 1
• 230000001225 therapeutic effect Effects 0.000 description 1