DE69930254T2 - Mikroströmungstechnischer gebenstand und verfahren zu seiner herstellung - Google Patents

Mikroströmungstechnischer gebenstand und verfahren zu seiner herstellung Download PDF

Info

Publication number
DE69930254T2
DE69930254T2 DE1999630254 DE69930254T DE69930254T2 DE 69930254 T2 DE69930254 T2 DE 69930254T2 DE 1999630254 DE1999630254 DE 1999630254 DE 69930254 T DE69930254 T DE 69930254T DE 69930254 T2 DE69930254 T2 DE 69930254T2
Authority
DE
Germany
Prior art keywords
substrate
article
microfluid
microfluid processing
tool
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE1999630254
Other languages
German (de)
English (en)
Other versions
DE69930254D1 (de
Inventor
G. James Saint Paul BENTSEN
P. Raymond Saint Paul JOHNSTON
W. Rolf Saint Paul BIERNATH
J. Richard Saint Paul POIRIER
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
3M Innovative Properties Co
Original Assignee
3M Innovative Properties Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3M Innovative Properties Co filed Critical 3M Innovative Properties Co
Publication of DE69930254D1 publication Critical patent/DE69930254D1/de
Application granted granted Critical
Publication of DE69930254T2 publication Critical patent/DE69930254T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C59/00—Surface shaping of articles, e.g. embossing; Apparatus therefor
    • B29C59/02—Surface shaping of articles, e.g. embossing; Apparatus therefor by mechanical means, e.g. pressing
    • B29C59/04—Surface shaping of articles, e.g. embossing; Apparatus therefor by mechanical means, e.g. pressing using rollers or endless belts
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/505—Containers for the purpose of retaining a material to be analysed, e.g. test tubes flexible containers not provided for above
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C39/00—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor
    • B29C39/14—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor for making articles of indefinite length
    • B29C39/148—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor for making articles of indefinite length characterised by the shape of the surface
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
    • B29C43/22—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor of articles of indefinite length
    • B29C43/222—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor of articles of indefinite length characterised by the shape of the surface
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C59/00—Surface shaping of articles, e.g. embossing; Apparatus therefor
    • B29C59/02—Surface shaping of articles, e.g. embossing; Apparatus therefor by mechanical means, e.g. pressing
    • B29C59/022—Surface shaping of articles, e.g. embossing; Apparatus therefor by mechanical means, e.g. pressing characterised by the disposition or the configuration, e.g. dimensions, of the embossments or the shaping tools therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/12—Specific details about manufacturing devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00009—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with a sample supporting tape, e.g. with absorbent zones
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S428/00—Stock material or miscellaneous articles
    • Y10S428/906—Roll or coil
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/24—Structurally defined web or sheet [e.g., overall dimension, etc.]
    • Y10T428/24479—Structurally defined web or sheet [e.g., overall dimension, etc.] including variation in thickness
    • Y10T428/24562—Interlaminar spaces
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/24—Structurally defined web or sheet [e.g., overall dimension, etc.]
    • Y10T428/24479—Structurally defined web or sheet [e.g., overall dimension, etc.] including variation in thickness
    • Y10T428/2457—Parallel ribs and/or grooves
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/24—Structurally defined web or sheet [e.g., overall dimension, etc.]
    • Y10T428/24479—Structurally defined web or sheet [e.g., overall dimension, etc.] including variation in thickness
    • Y10T428/24612—Composite web or sheet
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/24—Structurally defined web or sheet [e.g., overall dimension, etc.]
    • Y10T428/24744—Longitudinal or transverse tubular cavity or cell
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31678—Of metal

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Micromachines (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Shaping Of Tube Ends By Bending Or Straightening (AREA)
  • Casting Or Compression Moulding Of Plastics Or The Like (AREA)
  • Exposure Of Semiconductors, Excluding Electron Or Ion Beam Exposure (AREA)
DE1999630254 1998-06-18 1999-05-18 Mikroströmungstechnischer gebenstand und verfahren zu seiner herstellung Expired - Lifetime DE69930254T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US99562 1987-09-22
US09/099,562 US6375871B1 (en) 1998-06-18 1998-06-18 Methods of manufacturing microfluidic articles
PCT/US1999/011024 WO1999065664A1 (en) 1998-06-18 1999-05-18 Microfluidic articles and method of manufacturing same

Publications (2)

Publication Number Publication Date
DE69930254D1 DE69930254D1 (de) 2006-05-04
DE69930254T2 true DE69930254T2 (de) 2006-12-07

Family

ID=22275608

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1999630254 Expired - Lifetime DE69930254T2 (de) 1998-06-18 1999-05-18 Mikroströmungstechnischer gebenstand und verfahren zu seiner herstellung

Country Status (8)

Country Link
US (2) US6375871B1 (enExample)
EP (1) EP1087864B1 (enExample)
JP (2) JP4489945B2 (enExample)
KR (1) KR100618013B1 (enExample)
CN (1) CN100374283C (enExample)
AU (1) AU742931B2 (enExample)
DE (1) DE69930254T2 (enExample)
WO (1) WO1999065664A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007021544A1 (de) * 2007-05-08 2008-11-13 Siemens Ag Messeinheit und Verfahren zur optischen Untersuchung einer Flüssigkeit auf eine Analytkonzentration
DE102020114621A1 (de) 2020-06-02 2021-12-02 Joanneum Research Forschungsgesellschaft Mbh Bauteil mit Mikrofluidikstrukturen, Herstellungsverfahren und Verwendung

Families Citing this family (229)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5885470A (en) * 1997-04-14 1999-03-23 Caliper Technologies Corporation Controlled fluid transport in microfabricated polymeric substrates
US6375871B1 (en) 1998-06-18 2002-04-23 3M Innovative Properties Company Methods of manufacturing microfluidic articles
US6420622B1 (en) * 1997-08-01 2002-07-16 3M Innovative Properties Company Medical article having fluid control film
US6833242B2 (en) * 1997-09-23 2004-12-21 California Institute Of Technology Methods for detecting and sorting polynucleotides based on size
EP1032824A4 (en) 1997-10-15 2003-07-23 Aclara Biosciences Inc LAMINATED MICROSTRUCTURED DEVICE AND RELATED PRODUCTION METHOD
GB9808836D0 (en) * 1998-04-27 1998-06-24 Amersham Pharm Biotech Uk Ltd Microfabricated apparatus for cell based assays
US7223364B1 (en) 1999-07-07 2007-05-29 3M Innovative Properties Company Detection article having fluid control film
WO2001017797A1 (en) * 1999-09-10 2001-03-15 Caliper Technologies Corp. Microfabrication methods and devices
SE0000300D0 (sv) * 2000-01-30 2000-01-30 Amersham Pharm Biotech Ab Microfluidic assembly, covering method for the manufacture of the assembly and the use of the assembly
US6749813B1 (en) 2000-03-05 2004-06-15 3M Innovative Properties Company Fluid handling devices with diamond-like films
US7485454B1 (en) 2000-03-10 2009-02-03 Bioprocessors Corp. Microreactor
US20040132174A1 (en) * 2000-03-28 2004-07-08 Smith Allan Joseph Hilling Perfusion incubator
US6741523B1 (en) 2000-05-15 2004-05-25 3M Innovative Properties Company Microstructured time dependent indicators
US7062418B2 (en) * 2000-06-27 2006-06-13 Fluidigm Corporation Computer aided design method and system for developing a microfluidic system
US6627159B1 (en) * 2000-06-28 2003-09-30 3M Innovative Properties Company Centrifugal filling of sample processing devices
AU2001290879A1 (en) 2000-09-15 2002-03-26 California Institute Of Technology Microfabricated crossflow devices and methods
US6939451B2 (en) * 2000-09-19 2005-09-06 Aclara Biosciences, Inc. Microfluidic chip having integrated electrodes
EP1336097A4 (en) * 2000-10-13 2006-02-01 Fluidigm Corp SAMPLE INJECTION SYSTEM BASED ON A MICROFLUIDIC EQUIPMENT FOR ANALYTICAL EQUIPMENT
US7232109B2 (en) * 2000-11-06 2007-06-19 California Institute Of Technology Electrostatic valves for microfluidic devices
US8097471B2 (en) * 2000-11-10 2012-01-17 3M Innovative Properties Company Sample processing devices
JP2002214241A (ja) * 2000-11-20 2002-07-31 Minolta Co Ltd マイクロチップ
US20020108860A1 (en) * 2001-01-15 2002-08-15 Staats Sau Lan Tang Fabrication of polymeric microfluidic devices
US6531206B2 (en) 2001-02-07 2003-03-11 3M Innovative Properties Company Microstructured surface film assembly for liquid acquisition and transport
US6960437B2 (en) 2001-04-06 2005-11-01 California Institute Of Technology Nucleic acid amplification utilizing microfluidic devices
US6802342B2 (en) 2001-04-06 2004-10-12 Fluidigm Corporation Microfabricated fluidic circuit elements and applications
US6814938B2 (en) * 2001-05-23 2004-11-09 Nanostream, Inc. Non-planar microfluidic devices and methods for their manufacture
CA2702143C (en) 2001-06-05 2014-02-18 Mikro Systems, Inc. Methods for manufacturing three-dimensional devices and devices created thereby
US7785098B1 (en) 2001-06-05 2010-08-31 Mikro Systems, Inc. Systems for large area micro mechanical systems
US7141812B2 (en) * 2002-06-05 2006-11-28 Mikro Systems, Inc. Devices, methods, and systems involving castings
US7128876B2 (en) * 2001-07-17 2006-10-31 Agilent Technologies, Inc. Microdevice and method for component separation in a fluid
US7075162B2 (en) * 2001-08-30 2006-07-11 Fluidigm Corporation Electrostatic/electrostrictive actuation of elastomer structures using compliant electrodes
US7192629B2 (en) 2001-10-11 2007-03-20 California Institute Of Technology Devices utilizing self-assembled gel and method of manufacture
US8440093B1 (en) 2001-10-26 2013-05-14 Fuidigm Corporation Methods and devices for electronic and magnetic sensing of the contents of microfluidic flow channels
GB0128350D0 (en) 2001-11-27 2002-01-16 Lab901 Ltd Non-rigid apparatus for microfluidic applications
WO2003048295A1 (en) * 2001-11-30 2003-06-12 Fluidigm Corporation Microfluidic device and methods of using same
US7691333B2 (en) * 2001-11-30 2010-04-06 Fluidigm Corporation Microfluidic device and methods of using same
JP4157840B2 (ja) * 2001-12-11 2008-10-01 ザ プロクター アンド ギャンブル カンパニー 予備成形物の作製プロセス
US7140495B2 (en) 2001-12-14 2006-11-28 3M Innovative Properties Company Layered sheet construction for wastewater treatment
AU2002360822A1 (en) * 2001-12-17 2003-06-30 Aclara Biosicences, Inc. Microfluidic analytical apparatus
DE10201640A1 (de) * 2002-01-17 2003-08-07 Fraunhofer Ges Forschung Verfahren zur Herstellung einer Folie mit Oberflächenstrukturen im Mikro- und Nanometerbereich sowie eine diesbezügliche Folie
US7312085B2 (en) * 2002-04-01 2007-12-25 Fluidigm Corporation Microfluidic particle-analysis systems
EP2666849A3 (en) 2002-04-01 2014-05-28 Fluidigm Corporation Microfluidic particle-analysis systems
US6916116B2 (en) 2002-04-03 2005-07-12 3M Innovative Properties Company Time or time-temperature indicating articles
US6803090B2 (en) 2002-05-13 2004-10-12 3M Innovative Properties Company Fluid transport assemblies with flame retardant properties
US8206666B2 (en) * 2002-05-21 2012-06-26 Battelle Memorial Institute Reactors having varying cross-section, methods of making same, and methods of conducting reactions with varying local contact time
AU2003245424A1 (en) * 2002-06-06 2003-12-22 Rutgers, The State University Co-continuous phase composite polymer blends for in-vivo and in-vitro biomedical applications
WO2004000721A2 (en) * 2002-06-24 2003-12-31 Fluidigm Corporation Recirculating fluidic network and methods for using the same
US7201881B2 (en) * 2002-07-26 2007-04-10 Applera Corporation Actuator for deformable valves in a microfluidic device, and method
US7135147B2 (en) 2002-07-26 2006-11-14 Applera Corporation Closing blade for deformable valve in a microfluidic device and method
US20060234042A1 (en) * 2002-09-05 2006-10-19 Rui Yang Etched dielectric film in microfluidic devices
US6911132B2 (en) 2002-09-24 2005-06-28 Duke University Apparatus for manipulating droplets by electrowetting-based techniques
US7329545B2 (en) 2002-09-24 2008-02-12 Duke University Methods for sampling a liquid flow
WO2004028955A2 (en) 2002-09-25 2004-04-08 California Institute Of Technology Microfluidic large scale integration
AU2003299541A1 (en) 2002-10-02 2004-05-25 California Institute Of Technology Microfluidic nucleic acid analysis
US6913931B2 (en) 2002-10-03 2005-07-05 3M Innovative Properties Company Devices, methods and systems for low volume microarray processing
JP4009684B2 (ja) * 2002-10-28 2007-11-21 アークレイ株式会社 分析用具における液成分の温調方法、および分析用具
JP3866183B2 (ja) * 2002-11-01 2007-01-10 Ａｓｔｉ株式会社 バイオチップ
US6963007B2 (en) * 2002-12-19 2005-11-08 3M Innovative Properties Company Diacetylenic materials for sensing applications
US20040126897A1 (en) * 2002-12-19 2004-07-01 3M Innovative Properties Company Colorimetric sensors constructed of diacetylene materials
JP3856763B2 (ja) * 2003-03-11 2006-12-13 財団法人川村理化学研究所 マイクロ流体素子の製造方法
US20050145496A1 (en) * 2003-04-03 2005-07-07 Federico Goodsaid Thermal reaction device and method for using the same
US8828663B2 (en) * 2005-03-18 2014-09-09 Fluidigm Corporation Thermal reaction device and method for using the same
US7604965B2 (en) * 2003-04-03 2009-10-20 Fluidigm Corporation Thermal reaction device and method for using the same
US7476363B2 (en) * 2003-04-03 2009-01-13 Fluidigm Corporation Microfluidic devices and methods of using same
AU2004228678A1 (en) * 2003-04-03 2004-10-21 Fluidigm Corp. Microfluidic devices and methods of using same
US6986428B2 (en) 2003-05-14 2006-01-17 3M Innovative Properties Company Fluid separation membrane module
CA2526368A1 (en) * 2003-05-20 2004-12-02 Fluidigm Corporation Method and system for microfluidic device and imaging thereof
US7413712B2 (en) * 2003-08-11 2008-08-19 California Institute Of Technology Microfluidic rotary flow reactor matrix
US20050047967A1 (en) * 2003-09-03 2005-03-03 Industrial Technology Research Institute Microfluidic component providing multi-directional fluid movement
US7378451B2 (en) * 2003-10-17 2008-05-27 3M Innovative Properties Co Surfactant composition having stable hydrophilic character
US20050106360A1 (en) * 2003-11-13 2005-05-19 Johnston Raymond P. Microstructured surface building assemblies for fluid disposition
US7279215B2 (en) 2003-12-03 2007-10-09 3M Innovative Properties Company Membrane modules and integrated membrane cassettes
KR100572207B1 (ko) * 2003-12-18 2006-04-19 주식회사 디지탈바이오테크놀러지 플라스틱 마이크로 칩의 접합 방법
SE0400007D0 (sv) * 2004-01-02 2004-01-02 Gyros Ab Large scale surface modifiv´cation of microfluidic devices
WO2005065827A1 (en) * 2004-01-06 2005-07-21 Gyros Patent Ab Contact heating arrangement
US8030057B2 (en) * 2004-01-26 2011-10-04 President And Fellows Of Harvard College Fluid delivery system and method
AU2005209321B2 (en) 2004-01-26 2010-11-18 President And Fellows Of Harvard College Fluid delivery system and method
SE0400181D0 (sv) * 2004-01-29 2004-01-29 Gyros Ab Segmented porous and preloaded microscale devices
US20050210996A1 (en) * 2004-03-12 2005-09-29 Quinn John G Flow channel structure and method
JP2008506547A (ja) * 2004-06-21 2008-03-06 スリーエム イノベイティブ プロパティズ カンパニー 半導体ナノ粒子のパターン形成および配列
ATE485888T1 (de) * 2004-08-26 2010-11-15 Life Technologies Corp Elektrobenetzende abgabevorrichtungen und dazugehörige verfahren
DE602005024824D1 (de) * 2004-09-08 2010-12-30 Pacific Scient Energetic Materials Co Verfahren zur herstellung von substituierten tetrazolen aus aminotetrazolen
US8796583B2 (en) * 2004-09-17 2014-08-05 Eastman Kodak Company Method of forming a structured surface using ablatable radiation sensitive material
CA2583360C (en) 2004-10-06 2016-01-26 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Microtechnology-based dialyzer
US7955504B1 (en) 2004-10-06 2011-06-07 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Microfluidic devices, particularly filtration devices comprising polymeric membranes, and method for their manufacture and use
DE102004050062A1 (de) * 2004-10-13 2006-04-27 Boehringer Ingelheim Microparts Gmbh Vorrichtung, Meßgerät und Verfahren zur Aufnahme und Untersuchung oder Manipulation von Probenflüssigkeiten in einer mikrofluidischen Plattform
WO2006073738A2 (en) * 2004-12-17 2006-07-13 3M Innovative Properties Company Colorimetric sensors constructed of diacetylene materials
EP2329883B1 (en) * 2005-01-20 2013-05-01 3M Innovative Properties Co. Structured polymer films and methods for forming the same
US20060157381A1 (en) * 2005-01-20 2006-07-20 Adams James T Component carrier and method for making
WO2006081558A2 (en) 2005-01-28 2006-08-03 Duke University Apparatuses and methods for manipulating droplets on a printed circuit board
US7454988B2 (en) * 2005-02-10 2008-11-25 Applera Corporation Method for fluid sampling using electrically controlled droplets
US20060245933A1 (en) * 2005-05-02 2006-11-02 General Electric Company Valve and pump for microfluidic systems and methods for fabrication
WO2007000833A1 (ja) * 2005-06-29 2007-01-04 Harima Chemicals, Inc. 導電性回路の形成方法
JP4679992B2 (ja) * 2005-07-27 2011-05-11 大日本印刷株式会社 エンボス加工装置およびエンボス加工方法
US20070134739A1 (en) * 2005-12-12 2007-06-14 Gyros Patent Ab Microfluidic assays and microfluidic devices
WO2007075444A2 (en) * 2005-12-16 2007-07-05 Indiana University Research & Technology Corporation Sub-micron surface plasmon resonance sensor systems
US8355136B2 (en) 2005-12-16 2013-01-15 Indiana University Research And Technology Corporation Sub-micron surface plasmon resonance sensor systems
EP1986949A4 (en) * 2006-01-24 2013-11-27 Mycrolab Diagnostics Pty Ltd PUNCHING METHOD AND DEVICES
FR2897858B1 (fr) * 2006-02-27 2008-06-20 Commissariat Energie Atomique Procede de fabrication d'un reseau de capillaires d'une puce
EP1996704A2 (en) * 2006-03-08 2008-12-03 Barry Beroth Thin sheet for retaining biomolecules
EP1998891B1 (en) * 2006-03-20 2016-08-31 Koninklijke Philips N.V. A system-in-package platform for electronic-microfluidic devices
US20140193807A1 (en) 2006-04-18 2014-07-10 Advanced Liquid Logic, Inc. Bead manipulation techniques
US8492168B2 (en) * 2006-04-18 2013-07-23 Advanced Liquid Logic Inc. Droplet-based affinity assays
US8637317B2 (en) * 2006-04-18 2014-01-28 Advanced Liquid Logic, Inc. Method of washing beads
US8613889B2 (en) * 2006-04-13 2013-12-24 Advanced Liquid Logic, Inc. Droplet-based washing
US9476856B2 (en) 2006-04-13 2016-10-25 Advanced Liquid Logic, Inc. Droplet-based affinity assays
US8470606B2 (en) * 2006-04-18 2013-06-25 Duke University Manipulation of beads in droplets and methods for splitting droplets
US8658111B2 (en) 2006-04-18 2014-02-25 Advanced Liquid Logic, Inc. Droplet actuators, modified fluids and methods
US8716015B2 (en) 2006-04-18 2014-05-06 Advanced Liquid Logic, Inc. Manipulation of cells on a droplet actuator
US8389297B2 (en) * 2006-04-18 2013-03-05 Duke University Droplet-based affinity assay device and system
US7901947B2 (en) 2006-04-18 2011-03-08 Advanced Liquid Logic, Inc. Droplet-based particle sorting
US10078078B2 (en) 2006-04-18 2018-09-18 Advanced Liquid Logic, Inc. Bead incubation and washing on a droplet actuator
US7763471B2 (en) * 2006-04-18 2010-07-27 Advanced Liquid Logic, Inc. Method of electrowetting droplet operations for protein crystallization
US8637324B2 (en) 2006-04-18 2014-01-28 Advanced Liquid Logic, Inc. Bead incubation and washing on a droplet actuator
US7816121B2 (en) * 2006-04-18 2010-10-19 Advanced Liquid Logic, Inc. Droplet actuation system and method
US8809068B2 (en) 2006-04-18 2014-08-19 Advanced Liquid Logic, Inc. Manipulation of beads in droplets and methods for manipulating droplets
WO2007123908A2 (en) 2006-04-18 2007-11-01 Advanced Liquid Logic, Inc. Droplet-based multiwell operations
US7439014B2 (en) * 2006-04-18 2008-10-21 Advanced Liquid Logic, Inc. Droplet-based surface modification and washing
US8980198B2 (en) 2006-04-18 2015-03-17 Advanced Liquid Logic, Inc. Filler fluids for droplet operations
US7815871B2 (en) * 2006-04-18 2010-10-19 Advanced Liquid Logic, Inc. Droplet microactuator system
US8041463B2 (en) * 2006-05-09 2011-10-18 Advanced Liquid Logic, Inc. Modular droplet actuator drive
US7822510B2 (en) * 2006-05-09 2010-10-26 Advanced Liquid Logic, Inc. Systems, methods, and products for graphically illustrating and controlling a droplet actuator
US7939021B2 (en) * 2007-05-09 2011-05-10 Advanced Liquid Logic, Inc. Droplet actuator analyzer with cartridge
US20080108122A1 (en) * 2006-09-01 2008-05-08 State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon Microchemical nanofactories
CN101578520B (zh) 2006-10-18 2015-09-16 哈佛学院院长等 基于形成图案的多孔介质的横向流动和穿过生物测定装置、及其制备方法和使用方法
US20080138248A1 (en) * 2006-12-11 2008-06-12 Institut Curie Method for improving the bonding properties of microstructured substrates, and devices prepared with this method
GB2445738A (en) * 2007-01-16 2008-07-23 Lab901 Ltd Microfluidic device
GB2445739A (en) 2007-01-16 2008-07-23 Lab901 Ltd Polymeric laminates containing heat seals
CN103495439B (zh) * 2007-05-04 2015-09-16 欧普科诊断有限责任公司 流体连接器和微流体系统
JP2008284626A (ja) * 2007-05-16 2008-11-27 Miraial Kk マイクロ流路デバイス
US8920879B2 (en) * 2007-06-08 2014-12-30 Board Of Trustees Of The University Of Illinois Self-healing materials with microfluidic networks
US8298496B2 (en) * 2007-07-23 2012-10-30 Flir Systems, Inc. Fluidic configuration for flow injection analysis
US8268246B2 (en) 2007-08-09 2012-09-18 Advanced Liquid Logic Inc PCB droplet actuator fabrication
US8702932B2 (en) * 2007-08-30 2014-04-22 Pepex Biomedical, Inc. Electrochemical sensor and method for manufacturing
US9044178B2 (en) 2007-08-30 2015-06-02 Pepex Biomedical, Llc Electrochemical sensor and method for manufacturing
US20090130746A1 (en) * 2007-10-25 2009-05-21 Canon U.S. Life Sciences, Inc. Microchannel surface coating
JP2011504236A (ja) * 2007-11-20 2011-02-03 スリーエム イノベイティブ プロパティズ カンパニー ジアセチレンを含むポリマーセンサーを用いる細菌試料の分析方法
US20090211977A1 (en) * 2008-02-27 2009-08-27 Oregon State University Through-plate microchannel transfer devices
US8431671B2 (en) * 2008-03-26 2013-04-30 3M Innovative Properties Company Structured polydiorganosiloxane polyamide containing devices and methods
EP2265959B1 (en) * 2008-03-27 2014-03-05 President and Fellows of Harvard College Paper-based cellular arrays
AU2009228012A1 (en) * 2008-03-27 2009-10-01 President And Fellows Of Harvard College Paper-based microfluidic systems
CN102016594B (zh) * 2008-03-27 2014-04-23 哈佛学院院长等 用作低成本多重分析诊断平台的棉线
AU2009228091B2 (en) 2008-03-27 2015-05-21 President And Fellows Of Harvard College Three-dimensional microfluidic devices
EP2285491A1 (en) * 2008-04-25 2011-02-23 Claros Diagnostics, Inc. Flow control in microfluidic systems
EP2623632A3 (en) * 2008-06-30 2017-01-18 3M Innovative Properties Company Method of forming a microstructure
EP2311301B1 (en) * 2008-06-30 2012-04-25 3M Innovative Properties Company Method of forming a patterned substrate
EP2559535A3 (en) 2008-09-26 2016-09-07 Mikro Systems Inc. Systems, devices, and/or methods for manufacturing castings
WO2010039926A1 (en) * 2008-10-02 2010-04-08 Douglas Machine Inc. Microwell sampling tape sealing apparatus and methods
US8506740B2 (en) * 2008-11-14 2013-08-13 Pepex Biomedical, Llc Manufacturing electrochemical sensor module
US8951377B2 (en) 2008-11-14 2015-02-10 Pepex Biomedical, Inc. Manufacturing electrochemical sensor module
WO2010056878A2 (en) 2008-11-14 2010-05-20 Pepex Biomedical, Llc Electrochemical sensor module
EP2376226B1 (en) 2008-12-18 2018-09-12 Opko Diagnostics, LLC Improved reagent storage in microfluidic systems and related articles and methods
ES2695039T3 (es) 2009-02-02 2018-12-28 Opko Diagnostics, Llc Estructuras para controlar la interacción de luz con dispositivos microfluídicos
US9192933B2 (en) 2009-03-06 2015-11-24 President And Fellows Of Harvard College Microfluidic, electrochemical devices
EP2244489A1 (de) * 2009-04-24 2010-10-27 Bayer MaterialScience AG Verfahren zur Herstellung eines elektromechanischen Wandlers
US20100326914A1 (en) * 2009-06-24 2010-12-30 State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon Microfluidic devices
US8801922B2 (en) * 2009-06-24 2014-08-12 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Dialysis system
WO2011049097A1 (ja) * 2009-10-21 2011-04-28 旭硝子株式会社 インプリント用モールド、その製造方法、インプリント装置およびインプリント方法
US20130004967A1 (en) 2009-11-23 2013-01-03 Halverson Kurt J Microwell array articles and methods of use
MX336714B (es) 2009-11-24 2016-01-28 Opko Diagnostics Llc Mezclado y entrega de fluidos en sistemas microfluidicos.
US20110189048A1 (en) * 2009-12-05 2011-08-04 Curtis James R Modular dialysis system
US8753515B2 (en) 2009-12-05 2014-06-17 Home Dialysis Plus, Ltd. Dialysis system with ultrafiltration control
WO2011091007A2 (en) * 2010-01-20 2011-07-28 Nexcelom Bioscience Llc Cell counting and sample chamber and methods of fabrication
CA2788113A1 (en) 2010-02-03 2011-08-11 President And Fellows Of Harvard College Devices and methods for multiplexed assays
JP5585138B2 (ja) * 2010-03-17 2014-09-10 オムロン株式会社 流路チップ及び治具
AU2011239538B2 (en) 2010-04-16 2014-10-23 Opko Diagnostics, Llc Systems and devices for analysis of samples
US8580161B2 (en) 2010-05-04 2013-11-12 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Fluidic devices comprising photocontrollable units
USD645971S1 (en) 2010-05-11 2011-09-27 Claros Diagnostics, Inc. Sample cassette
US8501009B2 (en) 2010-06-07 2013-08-06 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Fluid purification system
CN102069564B (zh) * 2010-11-12 2013-12-04 中南大学 用于微流控芯片制造的旋转多工位注射成型模具
US9504162B2 (en) 2011-05-20 2016-11-22 Pepex Biomedical, Inc. Manufacturing electrochemical sensor modules
WO2013009927A2 (en) 2011-07-11 2013-01-17 Advanced Liquid Logic, Inc. Droplet actuators and techniques for droplet-based assays
US20130090633A1 (en) * 2011-10-07 2013-04-11 University Of Southern California Osmotic patch pump
WO2013052680A2 (en) 2011-10-07 2013-04-11 Home Dialysis Plus, Ltd. Heat exchange fluid purification for dialysis system
BR112014011270A2 (pt) 2011-11-02 2017-05-02 3M Innovative Properties Co lubrificante inibidor de ferrugem
US11092977B1 (en) 2017-10-30 2021-08-17 Zane Coleman Fluid transfer component comprising a film with fluid channels
US8813824B2 (en) 2011-12-06 2014-08-26 Mikro Systems, Inc. Systems, devices, and/or methods for producing holes
MX362555B (es) 2012-03-05 2019-01-24 Oy Arctic Partners Ab Metodos y aparatos para predecir riesgo de cancer de prostata y volumen de glandula prostatica.
JP2013224188A (ja) * 2012-04-20 2013-10-31 Nippon Electric Glass Co Ltd ベルトコンベア
WO2014031523A2 (en) * 2012-08-19 2014-02-27 University Of Rochester Method for preparing microfluidic device with reduced channel height
CN104918551B (zh) 2012-12-03 2019-07-26 Pepex生物医药有限公司 传感器模块以及使用传感器模块的方法
US10040018B2 (en) 2013-01-09 2018-08-07 Imagine Tf, Llc Fluid filters and methods of use
ES2649740T3 (es) 2013-01-22 2018-01-15 Pacific Scientific Energetic Materials Company Método simple para la preparación de 5-nitrotetrazolatos usando un sistema de flujo
US9588027B2 (en) 2013-03-13 2017-03-07 UPKO Diagnostics, LLC Mixing of fluids in fluidic systems
WO2015003722A1 (en) * 2013-07-10 2015-01-15 Delta Dansk Elektronik, Lys & Akustik Single-use device with a reaction chamber and a method for controlling the temperature in the device and uses thereof
US20150310392A1 (en) 2014-04-24 2015-10-29 Linkedin Corporation Job recommendation engine using a browsing history
WO2015164468A1 (en) 2014-04-24 2015-10-29 3M Innovative Properties Company Fluid control films with hydrophilic surfaces, methods of making same, and processes for cleaning structured surfaces
JP6657186B2 (ja) 2014-04-29 2020-03-04 アウトセット・メディカル・インコーポレイテッドＯｕｔｓｅｔ Ｍｅｄｉｃａｌ， Ｉｎｃ． 透析システムおよび方法
US9861920B1 (en) 2015-05-01 2018-01-09 Imagine Tf, Llc Three dimensional nanometer filters and methods of use
US11045124B2 (en) 2014-06-04 2021-06-29 Pepex Biomedical, Inc. Electrochemical sensors and methods for making electrochemical sensors using advanced printing technology
US9598380B2 (en) 2014-06-12 2017-03-21 Sri International Facile method for preparation of 5-nitrotetrazolates using a batch system
US9686540B2 (en) 2014-06-23 2017-06-20 Xerox Corporation Robust colorimetric processing method for paper based sensors
US9266105B2 (en) * 2014-06-23 2016-02-23 Xerox Corporation System and method for forming bonded substrates
KR102238956B1 (ko) * 2014-06-24 2021-04-13 삼성전자주식회사 유체 분석 시트, 이를 포함하는 유체 분석 카트리지 및 유체 분석 카트리지의 제조방법
US10730047B2 (en) 2014-06-24 2020-08-04 Imagine Tf, Llc Micro-channel fluid filters and methods of use
US10124275B2 (en) 2014-09-05 2018-11-13 Imagine Tf, Llc Microstructure separation filters
US10330095B2 (en) * 2014-10-31 2019-06-25 Encite Llc Microelectromechanical systems fabricated with roll to roll processing
CN107206376B (zh) 2014-12-12 2021-07-09 欧普科诊断有限责任公司 包括通过模塑形成之流控系统的包含孵育通道的流控系统
WO2016115564A1 (en) 2015-01-16 2016-07-21 Pacific Scientific Energetic Materials Company Facile method for preparation of sodium 5-nitrotetrazolate using a flow system
WO2016133929A1 (en) 2015-02-18 2016-08-25 Imagine Tf, Llc Three dimensional filter devices and apparatuses
US10118842B2 (en) 2015-07-09 2018-11-06 Imagine Tf, Llc Deionizing fluid filter devices and methods of use
USD804682S1 (en) 2015-08-10 2017-12-05 Opko Diagnostics, Llc Multi-layered sample cassette
US10479046B2 (en) 2015-08-19 2019-11-19 Imagine Tf, Llc Absorbent microstructure arrays and methods of use
WO2017074464A1 (en) * 2015-10-30 2017-05-04 Hewlett-Packard Development Company, L.P. Microfluidic channel filter
US10852310B2 (en) 2015-12-11 2020-12-01 Opko Diagnostics, Llc Fluidic systems involving incubation of samples and/or reagents
KR102490286B1 (ko) * 2016-01-18 2023-01-19 도레이 카부시키가이샤 표면 구조 필름의 제조방법 및 제조장치
ES2908601T3 (es) 2016-08-19 2022-05-03 Outset Medical Inc Sistema y métodos de diálisis peritoneal
WO2018093447A2 (en) 2016-09-07 2018-05-24 Pacific Scientific Energetic Materials Company Purification of flow sodium 5- nitrotetrazolate solutions with copper modified cation exchange resin
JP6994507B2 (ja) 2016-12-05 2022-01-14 スリーエム イノベイティブ プロパティズ カンパニー 結露管理システム
US10121645B2 (en) * 2016-12-05 2018-11-06 National Institutes of Health (NIH) U.S. Department of Health and Human Services (DHHS), U.S. Government NIH Division of Extramural Inventions and Technology Resources (DEITR) Sheathless interface for capillary electrophoresis/electrospray ionization-mass spectrometry
EP3557976A4 (en) 2016-12-20 2020-08-12 3M Innovative Properties Company CONDENSATE COLLECTOR AND REGULATION SYSTEM
US10807092B2 (en) * 2017-03-15 2020-10-20 Electronics And Telecommunications Research Institute Microfluidic control system and microfluidic control method using the same
KR102564002B1 (ko) * 2017-03-15 2023-08-08 한국전자통신연구원 미세유체 제어 시스템 및 이를 이용한 미세유체 제어 방법
US11759558B2 (en) 2017-04-03 2023-09-19 United States Government As Represented By The Department Of Veterans Affairs Microfluidic diffusion devices and systems, and methods of manufacturing and using same
EP3642271B1 (en) 2017-06-23 2024-05-15 3M Innovative Properties Company Films with a primer layer containing composite particles that include an organic polymer portion and a siliceous portion
WO2018234916A1 (en) 2017-06-23 2018-12-27 3M Innovative Properties Company Films with a primer layer containing silica nanoparticles modified by an organic silane
CN109551754B (zh) * 2017-09-25 2024-11-19 长春工业大学 一种超声辅助辊对辊热纳米压印装置及方法
EP3732423A4 (en) 2017-12-29 2021-09-29 3M Innovative Properties Company MANAGEMENT OF CONDENSATION WITH LIQUID CONTROL FILM DEVICE
WO2019133459A1 (en) 2017-12-29 2019-07-04 3M Innovative Properties Company Managing condensation with fluid control film apparatus
USD878622S1 (en) * 2018-04-07 2020-03-17 Precision Nanosystems Inc. Microfluidic chip
US20210190410A1 (en) 2018-08-10 2021-06-24 3M Innovative Properties Company Condensation management apparatus with gutter assembly
BR112021003168A2 (pt) 2018-08-23 2021-05-11 Outset Medical, Inc. métodos para preparar um conjunto de tubos e um dialisador, para testar vazamentos, para preparar um conjunto de tubos, para melhorar a durabilidade e operação de uma ou mais bombas de deslocamento e para prover terapia de diálise, sistema de diálise, e, acessório de queima de bomba
BR112021021836A2 (pt) 2019-04-30 2022-01-04 Outset Medical Inc Métodos para calcular a pressão arterial, para criar dialisato em um sistema de diálise, para medir a porcentagem de rejeição em um sistema de diálise, para coletar e analisar plasma sanguíneo, para remover gás de um circuito extracorpóreo de um sistema de diálise, para inferir uma pressão de linha em um circuito extracorpóreo de um sistema de diálise, para prover terapia de diálise extracorpórea e intracorpórea, para montar um conjunto de tubos de paciente no estilo cartucho em uma máquina de diálise e para preparar uma máquina de diálise para terapia de diálise, câmaras de fluxo e de remoção de ar, sistema de diálise, subsistema de dispensação de dialisato, filtro de micróbio/endotoxina de uso único, dialisador, dispositivo para medir pressão de um sistema de diálise, e, conjunto de tubos de sangue
DE102019119571A1 (de) * 2019-07-18 2021-01-21 Uwe Beier Verfahren und Vorrichtung zur Herstellung eines Substratverbundes
EP3956654A4 (en) * 2019-07-24 2022-04-20 Hewlett-Packard Development Company, L.P. DIGITAL MICROFLUIDIC DEVICE WITH DROPLET TREATMENT COMPONENTS
WO2021021084A1 (en) * 2019-07-26 2021-02-04 General Electric Company Methods of forming thermoplastic print beads into net shape structures for use in additive manufacturing
CN114651041B (zh) 2019-11-21 2024-08-30 3M创新有限公司 包含聚环氧烷嵌段共聚物的微结构化膜、组合物和方法
WO2022167467A1 (en) * 2021-02-04 2022-08-11 Universiteit Maastricht A method for manufacturing a structure with at least one microchannel for fluid
EP4046715A1 (de) * 2021-02-18 2022-08-24 Joanneum Research Forschungsgesellschaft mbH Mikrofluidisches system aus einer gefalteten folie und herstellungsverfahren

Family Cites Families (109)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3442686A (en) 1964-03-13 1969-05-06 Du Pont Low permeability transparent packaging films
SE325370B (enExample) 1967-03-06 1970-06-29 Gambro Ab
US3520300A (en) 1967-03-15 1970-07-14 Amp Inc Surgical sponge and suction device
BE754658A (fr) 1969-08-12 1971-02-10 Merck Patent Gmbh Lamelle indicatrice, se composant d'une matiere capillaire impregnee, absorbante et gainee de feuilles
CA941280A (en) 1969-11-17 1974-02-05 Franklin R. Elevitch Method and apparatus for forming electrophoresis apparatus and the like
GB1354502A (en) 1970-08-28 1974-06-05 Ici Ltd Heat exchangers
BE794510A (fr) 1972-01-28 1973-05-16 World Inventions Ltd Perfectionnements apportes aux aspirateurs
US3812972A (en) 1972-05-02 1974-05-28 J Rosenblum Liquid filter and method for fabricating same
US3993566A (en) 1975-01-08 1976-11-23 Amerace Corporation Reverse osmosis apparatus
US4668558A (en) 1978-07-20 1987-05-26 Minnesota Mining And Manufacturing Company Shaped plastic articles having replicated microstructure surfaces
US4233029A (en) 1978-10-25 1980-11-11 Eastman Kodak Company Liquid transport device and method
US4200681A (en) 1978-11-13 1980-04-29 General Electric Company Glass coated polycarbonate articles
US4392362A (en) 1979-03-23 1983-07-12 The Board Of Trustees Of The Leland Stanford Junior University Micro miniature refrigerators
US4277966A (en) 1979-06-04 1981-07-14 Raytheon Company Method of manufacturing a foraminous plate
US4271119A (en) 1979-07-23 1981-06-02 Eastman Kodak Company Capillary transport device having connected transport zones
US4413407A (en) 1980-03-10 1983-11-08 Eastman Kodak Company Method for forming an electrode-containing device with capillary transport between electrodes
FR2481790A1 (fr) 1980-04-30 1981-11-06 Ecopol Element modulaire moule, et application de cet element modulaire aux echangeurs a plaques et aux procedes de separation a membrane
DE3212295A1 (de) 1982-04-02 1983-10-06 Friedrich Von Amelen Verfahren zum verbinden zweier flaechen von platten
US4601861A (en) 1982-09-30 1986-07-22 Amerace Corporation Methods and apparatus for embossing a precision optical pattern in a resinous sheet or laminate
US4533352A (en) 1983-03-07 1985-08-06 Pmt Inc. Microsurgical flexible suction mat
US4579555A (en) 1983-12-05 1986-04-01 Sil-Fab Corporation Surgical gravity drain having aligned longitudinally extending capillary drainage channels
US4552791A (en) 1983-12-09 1985-11-12 Cosden Technology, Inc. Plastic container with decreased gas permeability
DE3435661A1 (de) 1984-09-28 1986-04-03 Wilhelm 6000 Frankfurt Schuster Saugerduese
US4740468A (en) 1985-02-14 1988-04-26 Syntex (U.S.A.) Inc. Concentrating immunochemical test device and method
FR2579025B1 (fr) 1985-03-15 1987-04-10 Occidental Chem Co Pile a combustible a separation amelioree
US5133516A (en) 1985-05-31 1992-07-28 Minnesota Mining And Manufacturing Co. Drag reduction article
US4986496A (en) 1985-05-31 1991-01-22 Minnesota Mining And Manufacturing Drag reduction article
US4639748A (en) 1985-09-30 1987-01-27 Xerox Corporation Ink jet printhead with integral ink filter
AT396998B (de) 1985-12-09 1994-01-25 Ottosensors Corp Messeinrichtungen und rohranschluss sowie verfahren zur herstellung einer messeinrichtung und verfahren zur verbindung von rohren mit einer messeinrichtung bzw. zur herstellung von rohranschlüssen
US4906439A (en) 1986-03-25 1990-03-06 Pb Diagnostic Systems, Inc. Biological diagnostic device and method of use
JP2582066B2 (ja) 1987-03-19 1997-02-19 株式会社日立製作所 光機能性デバイス
US5249359A (en) 1987-03-20 1993-10-05 Kernforschungszentrum Karlsruhe Gmbh Process for manufacturing finely structured bodies such as heat exchangers
DE3709278A1 (de) 1987-03-20 1988-09-29 Kernforschungsz Karlsruhe Verfahren zur herstellung von feinstrukturkoerpern
US4950549A (en) 1987-07-01 1990-08-21 Minnesota Mining And Manufacturing Company Polypropylene articles and method for preparing same
US5078925A (en) 1987-07-01 1992-01-07 Minnesota Mining And Manufacturing Company Preparing polypropylene articles
US4867876A (en) 1987-10-02 1989-09-19 Kopf Henry B Filter plate, filter plate element, and filter comprising same
US4913858A (en) 1987-10-26 1990-04-03 Dennison Manufacturing Company Method of embossing a coated sheet with a diffraction or holographic pattern
SE460013B (sv) 1987-11-20 1989-09-04 Adolf Gunnar Gustafson Anordning foer att medelst undertryck avlaegsna partiklar, vaetskor etc.fraan ett underlag
US4871623A (en) 1988-02-19 1989-10-03 Minnesota Mining And Manufacturing Company Sheet-member containing a plurality of elongated enclosed electrodeposited channels and method
US5158557A (en) 1988-04-04 1992-10-27 Minnesota Mining And Manufacturing Company Refastenable adhesive tape closure
GB8809608D0 (en) * 1988-04-22 1988-05-25 Alcan Int Ltd Sol-gel method of making ceramics
US4908112A (en) 1988-06-16 1990-03-13 E. I. Du Pont De Nemours & Co. Silicon semiconductor wafer for analyzing micronic biological samples
US5132012A (en) 1988-06-24 1992-07-21 Hitachi, Ltd. Liquid chromatograph
US5175030A (en) 1989-02-10 1992-12-29 Minnesota Mining And Manufacturing Company Microstructure-bearing composite plastic articles and method of making
US5411858A (en) 1989-05-17 1995-05-02 Actimed Laboratories, Inc. Manufacturing process for sample initiated assay device
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
JPH03132705A (ja) 1989-10-19 1991-06-06 Brother Ind Ltd 光導波路アレイ及びその製造方法
US5014389A (en) 1989-11-15 1991-05-14 Concept Inc. Foot manipulated suction head and method for employing same
JPH03240005A (ja) 1990-02-19 1991-10-25 Brother Ind Ltd 光導波路アレイ
KR100198380B1 (ko) 1990-02-20 1999-06-15 데이비드 엠 모이어 개방된 모관로 구조물, 모관로 구조물을 제조하기 위한 개선된 방법 및 그 방법에 사용하기 위한 압출 다이
US5750015A (en) 1990-02-28 1998-05-12 Soane Biosciences Method and device for moving molecules by the application of a plurality of electrical fields
US5126022A (en) 1990-02-28 1992-06-30 Soane Tecnologies, Inc. Method and device for moving molecules by the application of a plurality of electrical fields
US5534576A (en) 1990-04-17 1996-07-09 E. I. Du Pont De Nemours And Company Sealant for electrochemical cells
SE470347B (sv) 1990-05-10 1994-01-31 Pharmacia Lkb Biotech Mikrostruktur för vätskeflödessystem och förfarande för tillverkning av ett sådant system
EP0557433A4 (en) 1990-11-16 1994-06-01 Abbott Lab Improved agglutination reaction device having geometrically modified chambers
US5698299A (en) 1991-02-28 1997-12-16 Dyconex Patente Ag Thin laminated microstructure with precisely aligned openings
US5474796A (en) 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface
US5605662A (en) 1993-11-01 1997-02-25 Nanogen, Inc. Active programmable electronic devices for molecular biological analysis and diagnostics
DE59108591D1 (de) 1991-12-06 1997-04-10 Ciba Geigy Ag Elektrophoretische Trennvorrichtung und elektrophoretisches Trennverfahren
US5514120A (en) 1991-12-18 1996-05-07 Minnesota Mining And Manufacturing Company Liquid management member for absorbent articles
AU670563B2 (en) 1991-12-18 1996-07-25 Minnesota Mining And Manufacturing Company Liquid management member for absorbent articles
US5227008A (en) 1992-01-23 1993-07-13 Minnesota Mining And Manufacturing Company Method for making flexible circuits
DE4210072A1 (de) 1992-03-27 1993-03-25 Daimler Benz Ag Vorrichtung zum auftragen zaeher klebermassen auf starre anklebeflaechen
US5176667A (en) 1992-04-27 1993-01-05 Debring Donald L Liquid collection apparatus
US5726026A (en) 1992-05-01 1998-03-10 Trustees Of The University Of Pennsylvania Mesoscale sample preparation device and systems for determination and processing of analytes
US5498392A (en) 1992-05-01 1996-03-12 Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification device and method
US5304487A (en) 1992-05-01 1994-04-19 Trustees Of The University Of Pennsylvania Fluid handling in mesoscale analytical devices
US5637469A (en) 1992-05-01 1997-06-10 Trustees Of The University Of Pennsylvania Methods and apparatus for the detection of an analyte utilizing mesoscale flow systems
US5296375A (en) 1992-05-01 1994-03-22 Trustees Of The University Of Pennsylvania Mesoscale sperm handling devices
US5265184A (en) 1992-05-28 1993-11-23 Motorola, Inc. Molded waveguide and method for making same
US5440332A (en) 1992-07-06 1995-08-08 Compa Computer Corporation Apparatus for page wide ink jet printing
JPH0724643B2 (ja) 1992-10-26 1995-03-22 東京コスモス電機株式会社 還流式掃除機及び吸引式掃除機
US5583211A (en) 1992-10-29 1996-12-10 Beckman Instruments, Inc. Surface activated organic polymers useful for location - specific attachment of nucleic acids, peptides, proteins and oligosaccharides
US5651888A (en) 1992-12-16 1997-07-29 Kubota Corporation Filtration membrane cartridge
US5399486A (en) 1993-02-18 1995-03-21 Biocircuits Corporation Disposable unit in diagnostic assays
US5401913A (en) 1993-06-08 1995-03-28 Minnesota Mining And Manufacturing Company Electrical interconnections between adjacent circuit board layers of a multi-layer circuit board
DE4328001C2 (de) 1993-08-20 1997-03-20 Dia Nielsen Gmbh Tintenbehälter
US5728446A (en) 1993-08-22 1998-03-17 Johnston; Raymond P. Liquid management film for absorbent articles
US5437651A (en) 1993-09-01 1995-08-01 Research Medical, Inc. Medical suction apparatus
US5450235A (en) 1993-10-20 1995-09-12 Minnesota Mining And Manufacturing Company Flexible cube-corner retroreflective sheeting
US5691846A (en) 1993-10-20 1997-11-25 Minnesota Mining And Manufacturing Company Ultra-flexible retroreflective cube corner composite sheetings and methods of manufacture
US5429807A (en) 1993-10-28 1995-07-04 Beckman Instruments, Inc. Method and apparatus for creating biopolymer arrays on a solid support surface
US6287517B1 (en) * 1993-11-01 2001-09-11 Nanogen, Inc. Laminated assembly for active bioelectronic devices
US5737457A (en) 1994-02-25 1998-04-07 Fci - Fiberchem, Inc. Chip level waveguide sensor
US6001229A (en) 1994-08-01 1999-12-14 Lockheed Martin Energy Systems, Inc. Apparatus and method for performing microfluidic manipulations for chemical analysis
US5510155A (en) 1994-09-06 1996-04-23 Becton, Dickinson And Company Method to reduce gas transmission
US5707799A (en) 1994-09-30 1998-01-13 Abbott Laboratories Devices and methods utilizing arrays of structures for analyte capture
US5658413A (en) 1994-10-19 1997-08-19 Hewlett-Packard Company Miniaturized planar columns in novel support media for liquid phase analysis
US5571410A (en) 1994-10-19 1996-11-05 Hewlett Packard Company Fully integrated miniaturized planar liquid sample handling and analysis device
US5641400A (en) 1994-10-19 1997-06-24 Hewlett-Packard Company Use of temperature control devices in miniaturized planar column devices and miniaturized total analysis systems
US5500071A (en) 1994-10-19 1996-03-19 Hewlett-Packard Company Miniaturized planar columns in novel support media for liquid phase analysis
US5645702A (en) 1995-06-07 1997-07-08 Hewlett-Packard Company Low voltage miniaturized column analytical apparatus and method
US5585069A (en) 1994-11-10 1996-12-17 David Sarnoff Research Center, Inc. Partitioned microelectronic and fluidic device array for clinical diagnostics and chemical synthesis
DE19501017C2 (de) 1995-01-14 2002-10-24 Michael Volkmer Chirurgisches Absauginstrument
US5757482A (en) 1995-04-20 1998-05-26 Perseptive Biosystems, Inc. Module for optical detection in microscale fluidic analyses
US5692263A (en) 1995-06-02 1997-12-02 Sorenson; R. Wayne Delicate dusting vacuum tool
US5856174A (en) 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
US5658802A (en) 1995-09-07 1997-08-19 Microfab Technologies, Inc. Method and apparatus for making miniaturized diagnostic arrays
JPH11513333A (ja) 1995-10-12 1999-11-16 ミネソタ マイニング アンド マニュファクチャリング カンパニー ミクロ構造ポリマ支持体
US5716825A (en) 1995-11-01 1998-02-10 Hewlett Packard Company Integrated nucleic acid analysis system for MALDI-TOF MS
US5705813A (en) 1995-11-01 1998-01-06 Hewlett-Packard Company Integrated planar liquid handling system for maldi-TOF MS
US5628735A (en) 1996-01-11 1997-05-13 Skow; Joseph I. Surgical device for wicking and removing fluid
US5721435A (en) 1996-04-09 1998-02-24 Hewlett Packard Company Methods and apparatus for measuring optical properties of biological and chemical substances
US5885470A (en) 1997-04-14 1999-03-23 Caliper Technologies Corporation Controlled fluid transport in microfabricated polymeric substrates
US6267858B1 (en) 1996-06-28 2001-07-31 Caliper Technologies Corp. High throughput screening assay systems in microscale fluidic devices
US5932315A (en) 1997-04-30 1999-08-03 Hewlett-Packard Company Microfluidic structure assembly with mating microfeatures
US6375871B1 (en) 1998-06-18 2002-04-23 3M Innovative Properties Company Methods of manufacturing microfluidic articles
US5842787A (en) 1997-10-09 1998-12-01 Caliper Technologies Corporation Microfluidic systems incorporating varied channel dimensions
US6167910B1 (en) * 1998-01-20 2001-01-02 Caliper Technologies Corp. Multi-layer microfluidic devices

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007021544A1 (de) * 2007-05-08 2008-11-13 Siemens Ag Messeinheit und Verfahren zur optischen Untersuchung einer Flüssigkeit auf eine Analytkonzentration
DE102020114621A1 (de) 2020-06-02 2021-12-02 Joanneum Research Forschungsgesellschaft Mbh Bauteil mit Mikrofluidikstrukturen, Herstellungsverfahren und Verwendung

Also Published As

Publication number Publication date
EP1087864B1 (en) 2006-03-08
US6375871B1 (en) 2002-04-23
JP2010111129A (ja) 2010-05-20
DE69930254D1 (de) 2006-05-04
EP1087864A1 (en) 2001-04-04
AU742931B2 (en) 2002-01-17
JP4489945B2 (ja) 2010-06-23
KR20010052934A (ko) 2001-06-25
US6761962B2 (en) 2004-07-13
KR100618013B1 (ko) 2006-08-31
AU4003299A (en) 2000-01-05
WO1999065664A1 (en) 1999-12-23
US20020098124A1 (en) 2002-07-25
JP2002518202A (ja) 2002-06-25
CN100374283C (zh) 2008-03-12
CN1305410A (zh) 2001-07-25

Similar Documents

Publication Publication Date Title
DE69930254T2 (de) Mikroströmungstechnischer gebenstand und verfahren zu seiner herstellung
DE60201442T2 (de) Materialzusammensetzungen für mikronäpfe einer elektrophoretischen anzeige
DE69535293T2 (de) Anistrop elektrisch leitfähiger Harzfilm
EP1216141B1 (de) Verfahren zum fremdstofffreien verbinden von zwei werkstücken aus kunststoff
DE60105979T2 (de) Verfahren zur herstellung von mikrostrukturen mit verschiedenen oberflächeneigenschaften in einem multischichtkörper durch plasmaätzen
DE10228767B4 (de) Mikrovorrichtung und Verfahren für eine Komponententrennung in einem Fluid
DE19708472C2 (de) Herstellverfahren für chemische Mikroreaktoren
DE69116631T2 (de) Prägewalze zum Prägen einer Trägerfolie für einen optischen Aufzeichnungsträger, Vorrichtung zum Herstellen der Trägerfolie für einen optischen Aufzeichnungsträger, Verfahren zum Herstellen der Trägerfolie für einen optischen Aufzeichnungsträger sowie dadurch hergestellter optischer Aufzeichnungsträger
DE60107231T2 (de) Verfahren zur herstellung von kodierten teilchen
DE10392199T5 (de) Folie mit Mikroarchitektur
DE10309583A1 (de) Mikroplatte mit einem integrierten mikrofluidischen System zum parallelen Verarbeiten winziger Fluidvolumen
DE4132726A1 (de) Anisotrop elektrisch leitende klebstoffzusammensetzung und damit verklebte schaltkarten
DE69520361T2 (de) Vorrichtung und kontinuierliches verfahren zur herstellung einer gerinnungstesteinrichtung
EP1073522B1 (de) Trägerplatte für eine geordnete aufnahme einer vielzahl von probenpartikeln
DE102019112254A1 (de) Mikrofluidische Anordnung, Verfahren zu deren Herstellung und Messsystem umfassend die mikrofluidische Anordnung sowie Verwendung
EP1125630B1 (de) Mikroreaktor mit verbessertem Wärmetauscher
EP1422194B1 (de) Verfahren zur Herstellung eines Werkzeugeinsatzes zum Spritzgiessen eines mikrostrukturierten Teils
DE102013203829B4 (de) Verfahren und Vorrichtung zur Herstellung beidseitig mikrostrukturierter Verbundfolien
WO2022175361A1 (de) Mikrofluidisches system aus einer gefalteten folie und herstellungsverfahren
DE10207393A1 (de) Rapid Prototyping durch Drucken von organischen Substanzen und deren Verfestigung
DE10153663B4 (de) Mikroanalytische Vorrichtung zum Erfassen von Nahe-Infrarot-Strahlung emittierenden Molekülen
DE10331714B4 (de) Verfahren zur Strukturierung der Oberfläche eines Substrats
DE10326223B4 (de) Verfahren zur Strukturierung dünner Schichten mittels optischer Lithographie und Anordnung zur Durchführung der optischen Lithographie
DE19846958A1 (de) Einrichtung zum Transport von kleinsten Flüssigkeitsmengen und Verfahren zu deren Herstellung
EP1023593A1 (de) Einrichtung zum transport von kleinsten flüssigkeitsmengen und verfahren zu deren herstellung

Legal Events

Date Code Title Description
8364 No opposition during term of opposition