DE69918105D1 - Orale zubereitung enthaltend einen biguanid und eine organische säure - Google Patents

Orale zubereitung enthaltend einen biguanid und eine organische säure

Info

Publication number
DE69918105D1
DE69918105D1 DE69918105T DE69918105T DE69918105D1 DE 69918105 D1 DE69918105 D1 DE 69918105D1 DE 69918105 T DE69918105 T DE 69918105T DE 69918105 T DE69918105 T DE 69918105T DE 69918105 D1 DE69918105 D1 DE 69918105D1
Authority
DE
Germany
Prior art keywords
biguanide
organic acid
preparation containing
oral preparation
oral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69918105T
Other languages
English (en)
Other versions
DE69918105T2 (de
Inventor
Hiroyuki Nishii
Hirohisa Kobayashi
Kazuya Otoda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Pharma Co Ltd
Original Assignee
Sumitomo Pharmaceuticals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Pharmaceuticals Co Ltd filed Critical Sumitomo Pharmaceuticals Co Ltd
Publication of DE69918105D1 publication Critical patent/DE69918105D1/de
Application granted granted Critical
Publication of DE69918105T2 publication Critical patent/DE69918105T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69918105T 1998-04-29 1999-04-26 Orale zubereitung enthaltend einen biguanid und eine organische säure Expired - Lifetime DE69918105T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP13612698 1998-04-29
JP13612698 1998-04-29
PCT/JP1999/002192 WO1999055320A1 (en) 1998-04-29 1999-04-26 Oral formulation comprising biguanide and an organic acid

Publications (2)

Publication Number Publication Date
DE69918105D1 true DE69918105D1 (de) 2004-07-22
DE69918105T2 DE69918105T2 (de) 2005-07-07

Family

ID=15167924

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69918105T Expired - Lifetime DE69918105T2 (de) 1998-04-29 1999-04-26 Orale zubereitung enthaltend einen biguanid und eine organische säure

Country Status (11)

Country Link
US (1) US6517870B1 (de)
EP (1) EP1082109B1 (de)
JP (1) JP5255604B2 (de)
AT (1) ATE269069T1 (de)
AU (1) AU3536299A (de)
CA (1) CA2330485C (de)
DE (1) DE69918105T2 (de)
DK (1) DK1082109T3 (de)
ES (1) ES2224634T3 (de)
PT (1) PT1082109E (de)
WO (1) WO1999055320A1 (de)

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JP2004505913A (ja) * 2000-08-07 2004-02-26 ランバクシー　シグネチャー，エルエルシー メトフォルミンの液体処方
JP4706096B2 (ja) * 2000-10-23 2011-06-22 大正製薬株式会社 不快な味を呈する塩基性薬物配合製剤
FR2818908B1 (fr) * 2000-12-29 2004-04-02 Dospharma Utilisation en tant que medicament d'un compose restituant in vivo des principes actifs
FR2818906B1 (fr) 2000-12-29 2004-04-02 Dospharma Association medicamenteuse d'une biguanine et d'un transporteur, par exemple de metformine et d'arginine
JP2004520473A (ja) 2001-01-18 2004-07-08 ジェンザイム コーポレーション 抗菌剤としてのヨネンポリマーおよびその使用
US7220312B2 (en) * 2002-03-13 2007-05-22 Micron Technology, Inc. Methods for treating semiconductor substrates
US7785627B2 (en) 2002-09-20 2010-08-31 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US8084058B2 (en) 2002-09-20 2011-12-27 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US9060941B2 (en) 2002-09-20 2015-06-23 Actavis, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US7959946B2 (en) 2002-09-20 2011-06-14 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US8992980B2 (en) 2002-10-25 2015-03-31 Boehringer Ingelheim Vetmedica Gmbh Water-soluble meloxicam granules
US20070053939A1 (en) * 2003-10-17 2007-03-08 Hideakira Yokoyama Biguanide drug-containing jelly preparation
JP4740740B2 (ja) * 2003-12-09 2011-08-03 大日本住友製薬株式会社 薬物含有粒子および該粒子を含む固形製剤
DE10360924A1 (de) * 2003-12-23 2005-07-28 IIP - Institut für industrielle Pharmazie, Forschungs- und Entwicklungsgesellschaft mbH Metformin-haltige pharmazeutische Zusammensetzung
EP1568369A1 (de) 2004-02-23 2005-08-31 Boehringer Ingelheim Vetmedica Gmbh Verwendung von Meloxicam zur Behandlung von Atemwegserkrankungen bei Schweinen
DE102005006539A1 (de) * 2005-02-11 2006-08-24 Merck Patent Gmbh Biguanid enthaltende Zusammensetzungen
PE20061245A1 (es) * 2005-03-30 2007-01-06 Generex Pharm Inc Composiciones para la transmision transmucosa oral de la metformina
ES2343432T3 (es) * 2005-04-26 2010-07-30 Dainippon Sumitomo Pharma Co., Ltd. Preparado granular que contiene un compuesto de biguanida.
EP1942877A4 (de) * 2005-11-02 2011-09-14 Teikoku Pharma Usa Inc Organoleptisch annehmbare orale dosierformen von ibuprofen, herstellungsverfahren und anwendung
US20080107787A1 (en) * 2006-11-02 2008-05-08 The Coca-Cola Company Anti-Diabetic Composition with High-Potency Sweetener
WO2008097861A2 (en) * 2007-02-02 2008-08-14 Braincells, Inc. MODULATION OF NEUROGENESIS WITH BIGUANIDES AND GSK3-ß AGENTS
WO2009014960A1 (en) * 2007-07-23 2009-01-29 Teikoku Pharma Usa, Inc. Organoleptically acceptable indole serotonin receptor agonist oral dosage formulations and methods of using the same
US9795568B2 (en) 2010-05-05 2017-10-24 Boehringer Ingelheim Vetmedica Gmbh Low concentration meloxicam tablets
WO2011154975A2 (en) 2010-06-08 2011-12-15 Cadila Healthcare Limited Pharmaceutical compositions of metformin
US9339543B2 (en) 2011-10-12 2016-05-17 Merck Sharp & Dohme Corp. Pharmaceutical compositions that inhibit disproportionation
US9382187B2 (en) 2012-07-10 2016-07-05 Thetis Pharmaceuticals Llc Tri-salt form of metformin
US8765811B2 (en) 2012-07-10 2014-07-01 Thetis Pharmaceuticals Llc Tri-salt form of metformin
EP3140316A1 (de) 2014-05-05 2017-03-15 Thetis Pharmaceuticals LLC Zusammensetzungen und verfahren im zusammenhang mit ionischen salzen von peptiden
US9242008B2 (en) 2014-06-18 2016-01-26 Thetis Pharmaceuticals Llc Mineral amino-acid complexes of fatty acids
CA2951923A1 (en) 2014-06-18 2015-12-23 Thetis Pharmaceuticals Llc Mineral amino-acid complexes of active agents
CA3026264A1 (en) 2016-06-03 2017-12-07 Thetis Pharmaceuticals Llc Compositions and methods relating to salts of specialized pro-resolving mediators

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB539076A (en) 1940-03-18 1941-08-27 Mergenthaler Setzmaschfab Gmbh Improvements in or relating to typographical composing machines
DE2124256A1 (en) 1971-05-15 1972-11-30 Dr Christian Brunnengraber Chemi sehe Fabrik & Co mbH 2400 Lübeck Oral antidiabetics - contg dicarboxylic amino acids
JPS5840529B2 (ja) * 1975-09-29 1983-09-06 明治製菓株式会社 ケイコウヨウセイザイノセイホウ
US4089957A (en) 1976-06-11 1978-05-16 Ab Kabi Therapeutic compositions against recurrent thrombosis
US5324748A (en) 1981-07-14 1994-06-28 Efamol Limited Method for enhancement of 1-series PG production
JPS60246325A (ja) 1984-05-18 1985-12-06 Takeda Chem Ind Ltd 苦味が軽減された苦味成分含有水性溶液
FR2611500B1 (fr) * 1987-03-06 1990-05-04 Lipha Emploi de derives du biguanide dans la preparation de medicaments
JP2643260B2 (ja) 1988-03-22 1997-08-20 藤沢薬品工業株式会社 シロップ剤
US4975465A (en) 1989-03-28 1990-12-04 American Home Products Corporation Orally administrable ibuprofen compositions
US5260275A (en) 1990-08-14 1993-11-09 Amylin Pharmaceuticals, Inc. Hypoglycemics
US5411755A (en) * 1993-02-16 1995-05-02 The Procter & Gamble Company Process and composition for sweet juice from cucurbitaceae fruit
JP2705787B2 (ja) 1994-09-30 1998-01-28 山之内製薬株式会社 苦味改善易服用性ｈ▲２▼ブロッカー固形製剤
JP3294033B2 (ja) * 1994-12-24 2002-06-17 俊博 森田 オブラート
JPH104939A (ja) * 1996-06-27 1998-01-13 Nippon Shinyaku Co Ltd 飲 料
JPH1036252A (ja) 1996-07-22 1998-02-10 Taisho Pharmaceut Co Ltd ベラドンナ（総）アルカロイド配合内服液剤
JP3658878B2 (ja) * 1996-08-05 2005-06-08 大正製薬株式会社 内服液剤
US6399658B1 (en) 1996-12-24 2002-06-04 Sumitomo Pharmaceuticals Co., Ltd. Composition containing ascorbic acid
EP1039890B1 (de) * 1997-12-08 2004-03-17 Bristol-Myers Squibb Company Neue metformin salze und verfahren

Also Published As

Publication number Publication date
WO1999055320A1 (en) 1999-11-04
JP2010195839A (ja) 2010-09-09
DK1082109T3 (da) 2004-08-09
EP1082109B1 (de) 2004-06-16
AU3536299A (en) 1999-11-16
ES2224634T3 (es) 2005-03-01
ATE269069T1 (de) 2004-07-15
CA2330485A1 (en) 1999-11-04
DE69918105T2 (de) 2005-07-07
CA2330485C (en) 2008-07-08
EP1082109A1 (de) 2001-03-14
JP5255604B2 (ja) 2013-08-07
US6517870B1 (en) 2003-02-11
PT1082109E (pt) 2004-10-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: DAINIPPON SUMITOMO PHARMA CO., LTD., OSAKA, JP