DE69907156D1 - Krebsbehandlung - Google Patents

Krebsbehandlung

Info

Publication number
DE69907156D1
DE69907156D1 DE69907156T DE69907156T DE69907156D1 DE 69907156 D1 DE69907156 D1 DE 69907156D1 DE 69907156 T DE69907156 T DE 69907156T DE 69907156 T DE69907156 T DE 69907156T DE 69907156 D1 DE69907156 D1 DE 69907156D1
Authority
DE
Germany
Prior art keywords
cancer treatment
cancerous
elevation
testing
cdk1
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69907156T
Other languages
English (en)
Other versions
DE69907156T2 (de
Inventor
Meek Warenius
Laurence Anthony Seabra
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Theryte Ltd
Original Assignee
Theryte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9803446A external-priority patent/GB2334577A/en
Priority claimed from GB9803447A external-priority patent/GB2334578A/en
Priority claimed from GBGB9812151.0A external-priority patent/GB9812151D0/en
Priority claimed from GB9814545A external-priority patent/GB2334579B/en
Priority claimed from GB9903035A external-priority patent/GB2335739A/en
Application filed by Theryte Ltd filed Critical Theryte Ltd
Publication of DE69907156D1 publication Critical patent/DE69907156D1/de
Application granted granted Critical
Publication of DE69907156T2 publication Critical patent/DE69907156T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4748—Details p53
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/91—Transferases (2.)
    • G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • G01N2333/91205—Phosphotransferases in general
    • G01N2333/9121—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
DE69907156T 1998-02-18 1999-02-18 Krebsbehandlung Expired - Fee Related DE69907156T2 (de)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
GB9803446A GB2334577A (en) 1998-02-18 1998-02-18 Resistance of p53 mutant cancer cells to cytoxic effects of (chemo)therapeutic agents involving assay of cyclin D1 protein
GB9803446 1998-02-18
GB9803447A GB2334578A (en) 1998-02-18 1998-02-18 Diagnosis of cancer involving assay of levels of cyclin-dependent kinase (CDK) isoenzymes
GB9803447 1998-02-18
GBGB9812151.0A GB9812151D0 (en) 1998-06-05 1998-06-05 Treating cancer
GB9812151 1998-06-05
GB9814545A GB2334579B (en) 1998-02-18 1998-07-03 Treating cancer
GB9814545 1998-07-03
GB9903035A GB2335739A (en) 1998-02-18 1999-02-10 Screening anti-cancer agents
GB9903035 1999-02-10
PCT/GB1999/000509 WO1999042837A1 (en) 1998-02-18 1999-02-18 Treating cancer

Publications (2)

Publication Number Publication Date
DE69907156D1 true DE69907156D1 (de) 2003-05-28
DE69907156T2 DE69907156T2 (de) 2004-02-12

Family

ID=27517448

Family Applications (6)

Application Number Title Priority Date Filing Date
DE69907152T Expired - Lifetime DE69907152D1 (de) 1998-02-18 1999-02-18 Krebsbehandlung
DE69907154T Expired - Fee Related DE69907154T2 (de) 1998-02-18 1999-02-18 Krebsbehandlung
DE69907151T Expired - Lifetime DE69907151D1 (de) 1998-02-18 1999-02-18 Krebsbehandlung
DE69907156T Expired - Fee Related DE69907156T2 (de) 1998-02-18 1999-02-18 Krebsbehandlung
DE69907153T Expired - Fee Related DE69907153T2 (de) 1998-02-18 1999-02-18 Krebsbehandlung
DE69907155T Expired - Fee Related DE69907155T2 (de) 1998-02-18 1999-02-18 Krebsbehandlung

Family Applications Before (3)

Application Number Title Priority Date Filing Date
DE69907152T Expired - Lifetime DE69907152D1 (de) 1998-02-18 1999-02-18 Krebsbehandlung
DE69907154T Expired - Fee Related DE69907154T2 (de) 1998-02-18 1999-02-18 Krebsbehandlung
DE69907151T Expired - Lifetime DE69907151D1 (de) 1998-02-18 1999-02-18 Krebsbehandlung

Family Applications After (2)

Application Number Title Priority Date Filing Date
DE69907153T Expired - Fee Related DE69907153T2 (de) 1998-02-18 1999-02-18 Krebsbehandlung
DE69907155T Expired - Fee Related DE69907155T2 (de) 1998-02-18 1999-02-18 Krebsbehandlung

Country Status (8)

Country Link
US (3) US6878526B1 (de)
EP (7) EP1057027A2 (de)
JP (7) JP2002504687A (de)
AT (6) ATE238558T1 (de)
AU (8) AU741632B2 (de)
CA (7) CA2321482A1 (de)
DE (6) DE69907152D1 (de)
WO (8) WO1999042828A2 (de)

Families Citing this family (39)

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US6995249B1 (en) * 1998-08-14 2006-02-07 Japan Science And Technology Corporation Nucleic acid capable of binding specifically to Ras target protein
US8124630B2 (en) * 1999-01-13 2012-02-28 Bayer Healthcare Llc ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
JP2002534468A (ja) * 1999-01-13 2002-10-15 バイエル コーポレイション ｐ３８キナーゼ阻害剤としてのω−カルボキシアリール置換ジフェニル尿素
AU2001245939A1 (en) * 2000-03-24 2001-10-08 Millennum Pharmaceuticals, Inc. Compositions and methods for the identification, assessment, prevention, and therapy of human cancers
AU2001259160A1 (en) * 2000-04-28 2001-11-12 Millennium Pharmaceuticals, Inc. Compositions and methods for the identification, assessment, prevention, and therapy of human cancers
US6905816B2 (en) 2000-11-27 2005-06-14 Intelligent Medical Devices, Inc. Clinically intelligent diagnostic devices and methods
US7371763B2 (en) * 2001-04-20 2008-05-13 Bayer Pharmaceuticals Corporation Inhibition of raf kinase using quinolyl, isoquinolyl or pyridyl ureas
US20080108672A1 (en) * 2002-01-11 2008-05-08 Bernd Riedl Omega-Carboxyaryl Substituted Diphenyl Ureas As Raf Kinase Inhibitors
WO2003068228A1 (en) * 2002-02-11 2003-08-21 Bayer Pharmaceuticals Corporation Aryl ureas with angiogenesis inhibiting activity
JP2003304884A (ja) * 2002-02-13 2003-10-28 Japan Found Cancer Res 抗がん剤の適合性予測方法
DE60325579D1 (de) * 2002-03-25 2009-02-12 Theryte Ltd Krebsbehandlung
GB2387385A (en) * 2002-03-25 2003-10-15 Theryte Ltd Chemotherapeutic agents for treating cancer
JP2005529616A (ja) * 2002-06-18 2005-10-06 アイアールエム エルエルシー 化学療法耐性腫瘍の診断および治療
DE602004025676D1 (de) * 2003-02-26 2010-04-08 Sysmex Corp Verfahren zur untersuchung einer zelle
US7557129B2 (en) * 2003-02-28 2009-07-07 Bayer Healthcare Llc Cyanopyridine derivatives useful in the treatment of cancer and other disorders
PT1636585E (pt) * 2003-05-20 2008-03-27 Bayer Pharmaceuticals Corp Diarilureias com actividade inibidora de cinase
US8637553B2 (en) 2003-07-23 2014-01-28 Bayer Healthcare Llc Fluoro substituted omega-carboxyaryl diphenyl urea for the treatment and prevention of diseases and conditions
US8021831B2 (en) 2003-08-25 2011-09-20 Board Of Regents, The University Of Texas System Taxane chemosensitivity prediction test
US20050136177A1 (en) * 2003-08-25 2005-06-23 Anthony Hesse Method for coloring landscaping materials using foamable dry colorant
AU2005215910B2 (en) * 2004-02-23 2008-05-01 Novartis Ag P53 wild-type as biomarker for the treatment with mTOR inhibitors in combination with a cytotoxic agent
US20060019268A1 (en) * 2004-03-26 2006-01-26 Research Development Foundation Molecular markers of cisplatin resistance in cancer and uses thereof
DE602005024964D1 (de) 2004-05-31 2011-01-05 Sysmex Corp Verfahren zur beurteilung der malignität einer säuger-krebszelle
CN101072883B (zh) * 2004-12-08 2012-05-23 安万特药物公司 测量对多西他赛抗药性或敏感性的方法
US7957910B2 (en) * 2005-01-31 2011-06-07 Sysmex Corporation Method for predicting effectiveness of chemotherapy
JP4944446B2 (ja) * 2005-01-31 2012-05-30 シスメックス株式会社 抗がん剤治療の有効性予測方法
EP2270226B1 (de) * 2005-03-31 2016-05-18 Two Cells Co., Ltd Verfahren zur Unterscheidung mesenchymaler Stammzellen mittels molekularem Marker und Nutzung dieses Marker
EP1906950A4 (de) * 2005-06-21 2008-09-24 Infinity Discovery Inc Ansamycin-formulierungen und anwendungsverfahren dafür
US7682785B2 (en) 2005-06-30 2010-03-23 Sysmex Corporation Method for predicting effectiveness of chemotherapy using anticancer agent
JP5046574B2 (ja) * 2005-06-30 2012-10-10 シスメックス株式会社 抗がん剤治療の有効性予測方法
JP4766969B2 (ja) 2005-09-14 2011-09-07 シスメックス株式会社 組織性質判定装置
EP1962892A4 (de) * 2005-11-22 2011-10-12 Univ South Florida Hemmung der zellproliferation
JP5111902B2 (ja) * 2007-03-14 2013-01-09 シスメックス株式会社 癌の診断支援装置
WO2008115561A2 (en) * 2007-03-21 2008-09-25 Bristol-Myers Squibb Company Biomarkers and methods for determining sensitivity to microtubule-stabilizing agents
BRPI0810835A2 (pt) * 2007-04-12 2015-06-16 Infinity Discovery Inc Formulações de hidroquinona ansamicina
EP2028600B1 (de) 2007-08-24 2016-10-26 Sysmex Corporation Diagnose-Hilfssystem für Krebs, Diagnosehilfe für Informationen über das Krebsverfahren und Computerprogrammprodukt
GB0804496D0 (en) 2008-03-11 2008-04-16 Theryte Ltd Treating cancer
US20100184851A1 (en) * 2008-08-29 2010-07-22 University Of South Florida Inhibition of cell proliferation
US8778921B2 (en) 2008-10-15 2014-07-15 Infinity Pharmaceuticals, Inc. Ansamycin hydroquinone compositions
US20120108563A1 (en) * 2009-05-19 2012-05-03 Infinity Pharmaceuticals, Inc. Methods Of Treating Liposarcoma

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK354487A (da) * 1986-07-11 1988-01-12 Noboru Yanaihara Oncogen-relaterede peptider
CA1339069C (en) * 1987-11-09 1997-07-29 Henry Lee Niman Polypeptide-induced monoclonal receptors to protein ligand
WO1991019006A1 (en) * 1990-06-01 1991-12-12 The United States Of America, As Represented By The Secretary, U.S. Department Of Commerce MONOCLONAL ANTIBODIES FOR IDENTIFICATION AND PREPARATION OF raf-1 ONCOPROTEIN
DE69333043T2 (de) * 1992-10-16 2004-05-06 Cold Spring Harbor Laboratory Umlagerung des cyclin komlexes und seine darauf bezogenen anwendungen
US5381224A (en) * 1993-08-30 1995-01-10 A. E. Dixon Scanning laser imaging system
DE4444969C1 (de) * 1994-12-16 1996-10-24 Orga Med Dr Med Erwin Klopfer Nachweis von Antikörpern gegen p53 in Körperflüssigkeiten
WO1997004316A1 (en) * 1995-07-20 1997-02-06 Paracelsian, Inc. Determination of the presence of abnormal cellular proliferation through the detection of one or more cyclin dependent kinases
US5714329A (en) * 1995-11-29 1998-02-03 Sequana Theraputics, Inc. Methods for the diagnosis of a genetic predisposition to cancer associated with variant CDK4 allele
AU714560B2 (en) * 1996-04-15 2000-01-06 Trustees Of The University Of Pennsylvania, The Sensitization of cells to radiation and chemotherapy
ATE333465T1 (de) * 1996-05-08 2006-08-15 Cyclacel Ltd Methoden und mittel zur hemmung der cdk4- aktivität
WO1998034118A1 (en) * 1997-01-30 1998-08-06 Yale University Diagnostic methods and compositions based on the distribution of rad51

Also Published As

Publication number Publication date
DE69907154D1 (de) 2003-05-28
ATE238556T1 (de) 2003-05-15
AU2630099A (en) 1999-09-06
EP1057030A2 (de) 2000-12-06
JP2002504353A (ja) 2002-02-12
DE69907155D1 (de) 2003-05-28
WO1999042821A3 (en) 1999-11-11
EP1057029B1 (de) 2003-04-23
DE69907151D1 (de) 2003-05-28
WO1999042839A2 (en) 1999-08-26
AU2630199A (en) 1999-09-06
JP2002504354A (ja) 2002-02-12
CA2321458A1 (en) 1999-08-26
US6521407B1 (en) 2003-02-18
AU2538099A (en) 1999-09-06
WO1999042828A3 (en) 2000-08-24
DE69907153D1 (de) 2003-05-28
EP1057028B1 (de) 2003-04-23
WO1999042837A1 (en) 1999-08-26
WO1999042090A3 (en) 1999-11-04
AU743454B2 (en) 2002-01-24
WO1999042835A1 (en) 1999-08-26
AU735896B2 (en) 2001-07-19
AU2538199A (en) 1999-09-06
ATE238553T1 (de) 2003-05-15
AU753588B2 (en) 2002-10-24
WO1999042834A3 (en) 1999-11-25
WO1999042821A2 (en) 1999-08-26
AU2537999A (en) 1999-09-06
AU749180B2 (en) 2002-06-20
WO1999042834A2 (en) 1999-08-26
WO1999042090A2 (en) 1999-08-26
ATE238558T1 (de) 2003-05-15
JP2002504688A (ja) 2002-02-12
CA2321479A1 (en) 1999-08-26
DE69907153T2 (de) 2004-01-29
WO1999042839A3 (en) 1999-10-28
EP1057032A2 (de) 2000-12-06
EP1057032B1 (de) 2003-04-23
CA2321482A1 (en) 1999-08-26
EP1057033B1 (de) 2003-04-23
ATE238557T1 (de) 2003-05-15
DE69907156T2 (de) 2004-02-12
ATE238554T1 (de) 2003-05-15
AU739001B2 (en) 2001-10-04
JP2002504496A (ja) 2002-02-12
CA2321481A1 (en) 1999-08-26
US6878526B1 (en) 2005-04-12
WO1999042836A1 (en) 1999-08-26
CA2321480A1 (en) 1999-08-26
AU2538299A (en) 1999-09-06
EP1057028A1 (de) 2000-12-06
JP2002504687A (ja) 2002-02-12
US20030134315A1 (en) 2003-07-17
DE69907154T2 (de) 2004-02-19
AU2538499A (en) 1999-09-06
AU741712B2 (en) 2001-12-06
JP2002503822A (ja) 2002-02-05
EP1057031A1 (de) 2000-12-06
WO1999042828A2 (en) 1999-08-26
DE69907152D1 (de) 2003-05-28
EP1057033A1 (de) 2000-12-06
AU2538599A (en) 1999-09-06
AU741632B2 (en) 2001-12-06
EP1057029A2 (de) 2000-12-06
EP1057027A2 (de) 2000-12-06
ATE238555T1 (de) 2003-05-15
EP1057031B1 (de) 2003-04-23
CA2321467A1 (en) 1999-08-26
EP1057030B1 (de) 2003-04-23
CA2321438A1 (en) 1999-08-26
JP2002504683A (ja) 2002-02-12
DE69907155T2 (de) 2004-02-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee