GB2334579B - Treating cancer - Google Patents

Treating cancer

Info

Publication number
GB2334579B
GB2334579B GB9814545A GB9814545A GB2334579B GB 2334579 B GB2334579 B GB 2334579B GB 9814545 A GB9814545 A GB 9814545A GB 9814545 A GB9814545 A GB 9814545A GB 2334579 B GB2334579 B GB 2334579B
Authority
GB
United Kingdom
Prior art keywords
treating cancer
cancer
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB9814545A
Other versions
GB2334579A (en
GB9814545D0 (en
Inventor
Hilmar Meek Warenius
Laurence Anthony Seabra
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Liverpool
Theryte Ltd
Original Assignee
University of Liverpool
Theryte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9803447A external-priority patent/GB2334578A/en
Priority claimed from GB9803446A external-priority patent/GB2334577A/en
Priority claimed from GBGB9812151.0A external-priority patent/GB9812151D0/en
Application filed by University of Liverpool, Theryte Ltd filed Critical University of Liverpool
Publication of GB9814545D0 publication Critical patent/GB9814545D0/en
Priority to DE69907152T priority Critical patent/DE69907152D1/en
Priority to JP2000532727A priority patent/JP2002504688A/en
Priority to US09/622,277 priority patent/US6521407B1/en
Priority to EP99905087A priority patent/EP1057032B1/en
Priority to PCT/GB1999/000505 priority patent/WO1999042836A1/en
Priority to JP2000532726A priority patent/JP2002504496A/en
Priority to DE69907153T priority patent/DE69907153T2/en
Priority to JP2000532728A priority patent/JP2002504354A/en
Priority to PCT/GB1999/000506 priority patent/WO1999042821A2/en
Priority to PCT/GB1999/000502 priority patent/WO1999042090A2/en
Priority to AT99905087T priority patent/ATE238557T1/en
Priority to JP2000532719A priority patent/JP2002504353A/en
Priority to AU25379/99A priority patent/AU743454B2/en
Priority to EP99905081A priority patent/EP1057027A2/en
Priority to AU26301/99A priority patent/AU2630199A/en
Priority to AU25380/99A priority patent/AU739001B2/en
Priority to AU25384/99A priority patent/AU741632B2/en
Priority to EP99905084A priority patent/EP1057030B1/en
Priority to CA002321481A priority patent/CA2321481A1/en
Priority to AT99905084T priority patent/ATE238555T1/en
Priority to DE69907155T priority patent/DE69907155T2/en
Priority to US09/622,577 priority patent/US6878526B1/en
Priority to EP99905082A priority patent/EP1057028B1/en
Priority to AT99906326T priority patent/ATE238558T1/en
Priority to CA002321438A priority patent/CA2321438A1/en
Priority to DE69907156T priority patent/DE69907156T2/en
Priority to CA002321480A priority patent/CA2321480A1/en
Priority to AT99905086T priority patent/ATE238556T1/en
Priority to PCT/GB1999/000500 priority patent/WO1999042834A2/en
Priority to CA002321479A priority patent/CA2321479A1/en
Priority to EP99905083A priority patent/EP1057029B1/en
Priority to AT99905082T priority patent/ATE238553T1/en
Priority to CA002321458A priority patent/CA2321458A1/en
Priority to JP2000532107A priority patent/JP2002503822A/en
Priority to AU25382/99A priority patent/AU741712B2/en
Priority to AU25385/99A priority patent/AU753588B2/en
Priority to JP2000532725A priority patent/JP2002504687A/en
Priority to AT99905083T priority patent/ATE238554T1/en
Priority to CA002321467A priority patent/CA2321467A1/en
Priority to CA002321482A priority patent/CA2321482A1/en
Priority to AU26300/99A priority patent/AU749180B2/en
Priority to EP99905086A priority patent/EP1057031B1/en
Priority to PCT/GB1999/000501 priority patent/WO1999042835A1/en
Priority to EP99906326A priority patent/EP1057033B1/en
Priority to AU25381/99A priority patent/AU735896B2/en
Priority to JP2000532712A priority patent/JP2002504683A/en
Priority to DE69907151T priority patent/DE69907151D1/en
Priority to PCT/GB1999/000512 priority patent/WO1999042839A2/en
Priority to PCT/GB1999/000509 priority patent/WO1999042837A1/en
Priority to PCT/GB1999/000503 priority patent/WO1999042828A2/en
Priority to DE69907154T priority patent/DE69907154T2/en
Publication of GB2334579A publication Critical patent/GB2334579A/en
Priority to US10/321,555 priority patent/US20030134315A1/en
Application granted granted Critical
Publication of GB2334579B publication Critical patent/GB2334579B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5748—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving oncogenic proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57496—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving intracellular compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2510/00—Detection of programmed cell death, i.e. apoptosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
GB9814545A 1998-02-18 1998-07-03 Treating cancer Expired - Fee Related GB2334579B (en)

Priority Applications (52)

Application Number Priority Date Filing Date Title
DE69907156T DE69907156T2 (en) 1998-02-18 1999-02-18 CANCER TREATMENT
CA002321479A CA2321479A1 (en) 1998-02-18 1999-02-18 Treating cancer
US09/622,277 US6521407B1 (en) 1998-02-18 1999-02-18 Methods for determining chemosensitivity of cancer cells based upon expression of negative and positive signal transduction factors
EP99905087A EP1057032B1 (en) 1998-02-18 1999-02-18 Treating cancer
PCT/GB1999/000505 WO1999042836A1 (en) 1998-02-18 1999-02-18 Treating cancer
JP2000532726A JP2002504496A (en) 1998-02-18 1999-02-18 Cancer Treatment
JP2000532727A JP2002504688A (en) 1998-02-18 1999-02-18 Cancer Treatment
JP2000532728A JP2002504354A (en) 1998-02-18 1999-02-18 Cancer Treatment
PCT/GB1999/000506 WO1999042821A2 (en) 1998-02-18 1999-02-18 Treating cancer
PCT/GB1999/000502 WO1999042090A2 (en) 1998-02-18 1999-02-18 Treating cancer
AT99905087T ATE238557T1 (en) 1998-02-18 1999-02-18 CANCER TREATMENT
JP2000532719A JP2002504353A (en) 1998-02-18 1999-02-18 Cancer Treatment
AU25379/99A AU743454B2 (en) 1998-02-18 1999-02-18 Treating cancer
EP99905081A EP1057027A2 (en) 1998-02-18 1999-02-18 Treating cancer
AU26301/99A AU2630199A (en) 1998-02-18 1999-02-18 Treating cancer
AU25380/99A AU739001B2 (en) 1998-02-18 1999-02-18 Treating cancer
AU25384/99A AU741632B2 (en) 1998-02-18 1999-02-18 Treating cancer
EP99905084A EP1057030B1 (en) 1998-02-18 1999-02-18 Treating cancer
CA002321481A CA2321481A1 (en) 1998-02-18 1999-02-18 Treating cancer
EP99905083A EP1057029B1 (en) 1998-02-18 1999-02-18 Treating cancer
DE69907155T DE69907155T2 (en) 1998-02-18 1999-02-18 CANCER TREATMENT
US09/622,577 US6878526B1 (en) 1998-02-18 1999-02-18 Treating cancer
EP99905082A EP1057028B1 (en) 1998-02-18 1999-02-18 Treating cancer
AT99906326T ATE238558T1 (en) 1998-02-18 1999-02-18 CANCER TREATMENT
CA002321438A CA2321438A1 (en) 1998-02-18 1999-02-18 Treating cancer
DE69907152T DE69907152D1 (en) 1998-02-18 1999-02-18 CANCER TREATMENT
CA002321480A CA2321480A1 (en) 1998-02-18 1999-02-18 Treating cancer
AT99905086T ATE238556T1 (en) 1998-02-18 1999-02-18 CANCER TREATMENT
PCT/GB1999/000500 WO1999042834A2 (en) 1998-02-18 1999-02-18 Treating cancer
DE69907153T DE69907153T2 (en) 1998-02-18 1999-02-18 CANCER TREATMENT
AT99905084T ATE238555T1 (en) 1998-02-18 1999-02-18 CANCER TREATMENT
AT99905082T ATE238553T1 (en) 1998-02-18 1999-02-18 CANCER TREATMENT
CA002321458A CA2321458A1 (en) 1998-02-18 1999-02-18 Treating cancer
JP2000532107A JP2002503822A (en) 1998-02-18 1999-02-18 Cancer Treatment
AU25382/99A AU741712B2 (en) 1998-02-18 1999-02-18 Treating cancer
AU25385/99A AU753588B2 (en) 1998-02-18 1999-02-18 Treating cancer
JP2000532725A JP2002504687A (en) 1998-02-18 1999-02-18 Cancer Treatment
AT99905083T ATE238554T1 (en) 1998-02-18 1999-02-18 CANCER TREATMENT
CA002321467A CA2321467A1 (en) 1998-02-18 1999-02-18 Treating cancer
CA002321482A CA2321482A1 (en) 1998-02-18 1999-02-18 Treating cancer
AU26300/99A AU749180B2 (en) 1998-02-18 1999-02-18 Treating cancer
EP99905086A EP1057031B1 (en) 1998-02-18 1999-02-18 Treating cancer
PCT/GB1999/000501 WO1999042835A1 (en) 1998-02-18 1999-02-18 Treating cancer
EP99906326A EP1057033B1 (en) 1998-02-18 1999-02-18 Treating cancer
AU25381/99A AU735896B2 (en) 1998-02-18 1999-02-18 Treating cancer
JP2000532712A JP2002504683A (en) 1998-02-18 1999-02-18 Cancer Treatment
DE69907151T DE69907151D1 (en) 1998-02-18 1999-02-18 CANCER TREATMENT
PCT/GB1999/000512 WO1999042839A2 (en) 1998-02-18 1999-02-18 Treating cancer
PCT/GB1999/000509 WO1999042837A1 (en) 1998-02-18 1999-02-18 Treating cancer
PCT/GB1999/000503 WO1999042828A2 (en) 1998-02-18 1999-02-18 Treating cancer
DE69907154T DE69907154T2 (en) 1998-02-18 1999-02-18 CANCER TREATMENT
US10/321,555 US20030134315A1 (en) 1998-02-18 2002-12-18 Treating cancer

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9803447A GB2334578A (en) 1998-02-18 1998-02-18 Diagnosis of cancer involving assay of levels of cyclin-dependent kinase (CDK) isoenzymes
GB9803446A GB2334577A (en) 1998-02-18 1998-02-18 Resistance of p53 mutant cancer cells to cytoxic effects of (chemo)therapeutic agents involving assay of cyclin D1 protein
GBGB9812151.0A GB9812151D0 (en) 1998-06-05 1998-06-05 Treating cancer

Publications (3)

Publication Number Publication Date
GB9814545D0 GB9814545D0 (en) 1998-09-02
GB2334579A GB2334579A (en) 1999-08-25
GB2334579B true GB2334579B (en) 2003-06-04

Family

ID=27269218

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9814545A Expired - Fee Related GB2334579B (en) 1998-02-18 1998-07-03 Treating cancer

Country Status (1)

Country Link
GB (1) GB2334579B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110196327A (en) * 2019-05-18 2019-09-03 贵州医科大学附属医院 Kit based on genetic variation analysis detection rectum cancer cell drug susceptibility

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994017413A1 (en) * 1993-01-21 1994-08-04 Paracelsian, Inc. Products for measuring cell growth propensity and methods for their use
WO1997004316A1 (en) * 1995-07-20 1997-02-06 Paracelsian, Inc. Determination of the presence of abnormal cellular proliferation through the detection of one or more cyclin dependent kinases
WO1997009617A1 (en) * 1995-09-06 1997-03-13 Arch Development Corporation Screening methods for the identification of inducers and inhibitors of programmed cell death (apoptosis)
WO1997034146A1 (en) * 1996-03-12 1997-09-18 The General Hospital Corporation Inhibiting protein interactions
WO1998013690A1 (en) * 1996-09-27 1998-04-02 Cold Spring Harbor Laboratory Oncogene-induced apoptosis in drug-resistant cells

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994017413A1 (en) * 1993-01-21 1994-08-04 Paracelsian, Inc. Products for measuring cell growth propensity and methods for their use
WO1997004316A1 (en) * 1995-07-20 1997-02-06 Paracelsian, Inc. Determination of the presence of abnormal cellular proliferation through the detection of one or more cyclin dependent kinases
WO1997009617A1 (en) * 1995-09-06 1997-03-13 Arch Development Corporation Screening methods for the identification of inducers and inhibitors of programmed cell death (apoptosis)
WO1997034146A1 (en) * 1996-03-12 1997-09-18 The General Hospital Corporation Inhibiting protein interactions
WO1998013690A1 (en) * 1996-09-27 1998-04-02 Cold Spring Harbor Laboratory Oncogene-induced apoptosis in drug-resistant cells

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
Annals of Oncology 1995,6,589-593 *
Anti-Cancer Drugs 1997,8,903-910 *
CANCER RESEARCH, VOL 57, 1997, LI, W-W ET AL., PAGES 2193-2199. *
INT. J. CANCER, VOL 68, 1996, LI. W-W. ET AL., PAGES 514-519 *
INT. J. CANCER, VOL 74, 1997, MAEDA, K. ET AL., PAGES 310-315 *
J.National Cancer Institute 1996,88(18),1269-1275 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110196327A (en) * 2019-05-18 2019-09-03 贵州医科大学附属医院 Kit based on genetic variation analysis detection rectum cancer cell drug susceptibility
CN110196327B (en) * 2019-05-18 2022-04-29 贵州医科大学附属医院 Kit for detecting drug sensitivity of rectal cancer cells based on gene variation analysis

Also Published As

Publication number Publication date
GB2334579A (en) 1999-08-25
GB9814545D0 (en) 1998-09-02

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Legal Events

Date Code Title Description
COOA Change in applicant's name or ownership of the application
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20090703