DE69838750T2 - Zeitverzögerte gelzusammensetzungen mit verlängerter wirkstoffverabreichung - Google Patents
Zeitverzögerte gelzusammensetzungen mit verlängerter wirkstoffverabreichung Download PDFInfo
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- DE69838750T2 DE69838750T2 DE69838750T DE69838750T DE69838750T2 DE 69838750 T2 DE69838750 T2 DE 69838750T2 DE 69838750 T DE69838750 T DE 69838750T DE 69838750 T DE69838750 T DE 69838750T DE 69838750 T2 DE69838750 T2 DE 69838750T2
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Classifications
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
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- A—HUMAN NECESSITIES
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Epidemiology (AREA)
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- Emergency Medicine (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Child & Adolescent Psychology (AREA)
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- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (5)
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| US912902 | 1986-09-26 | ||
| US85797397A | 1997-05-16 | 1997-05-16 | |
| US857973 | 1997-05-16 | ||
| US91290297A | 1997-08-15 | 1997-08-15 | |
| PCT/US1998/010013 WO1998051348A2 (en) | 1997-05-16 | 1998-05-18 | Sustained-release delayed gels |
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| DE69838750D1 DE69838750D1 (de) | 2008-01-03 |
| DE69838750T2 true DE69838750T2 (de) | 2008-10-30 |
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| WO (1) | WO1998051348A2 (enExample) |
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| AU2003200609B2 (en) * | 1998-05-18 | 2006-02-23 | Amgen Inc. | Biodegradable sustained-release alginate gels |
| US6432449B1 (en) * | 1998-05-18 | 2002-08-13 | Amgen Inc. | Biodegradable sustained-release alginate gels |
| JP2000256216A (ja) * | 1999-03-04 | 2000-09-19 | Meiji Milk Prod Co Ltd | ゲル組成物 |
| US7582311B1 (en) | 1999-10-15 | 2009-09-01 | Genentech, Inc. | Injection vehicle for polymer-based formulations |
| US7651703B2 (en) | 1999-10-15 | 2010-01-26 | Genentech, Inc. | Injection vehicle for polymer-based formulations |
| CA2396431A1 (en) * | 1999-11-29 | 2001-05-31 | Advanced Research And Technology Institute, Inc. | Sustained percutaneous delivery of a biologically active substance |
| FR2823119B1 (fr) * | 2001-04-05 | 2004-02-20 | Seppic Sa | Adjuvant d'immunite contenant un cation metallique complexe et vaccin le contenant |
| KR20050071611A (ko) * | 2002-10-25 | 2005-07-07 | 화이자 프로덕츠 인코포레이티드 | 현탁액 형태의 아릴헤테로환 활성제의 저장 제형 |
| WO2007073398A2 (en) * | 2005-05-23 | 2007-06-28 | Natural Alternatives International | Compositions and methods for the sustained release of beta-alanine |
| US20070202186A1 (en) | 2006-02-22 | 2007-08-30 | Iscience Interventional Corporation | Apparatus and formulations for suprachoroidal drug delivery |
| JP5107585B2 (ja) * | 2007-01-29 | 2012-12-26 | 株式会社 メドレックス | 低温充填ゼリー組成物とその製造方法 |
| EP1985286A1 (en) * | 2007-04-24 | 2008-10-29 | Biocompatibles UK Limited | Microspheres for treatment of brain tumours |
| BR112013009205A2 (pt) | 2010-10-15 | 2016-07-26 | Iscience Interventional Corp | dispositivo para colocação na esclera de um olho, método para acessar o espaço supracoroidal de um olho, para acessar o espaço subretinal de um olho e para colocar um orifício dentro de um trato escleral em um olho. |
| CA3240136A1 (en) | 2012-11-08 | 2014-05-15 | Clearside Biomedical, Inc. | Methods and devices for the treatment of ocular diseases in human subjects |
| SG10201702674PA (en) | 2013-05-03 | 2017-06-29 | Clearside Biomedical Inc | Apparatus and methods for ocular injection |
| US10010447B2 (en) | 2013-12-18 | 2018-07-03 | Novartis Ag | Systems and methods for subretinal delivery of therapeutic agents |
| RU2710491C2 (ru) | 2014-06-20 | 2019-12-26 | Клиасайд Байомедикал, Инк. | Устройство для инъекции лекарственного средства в глазную ткань и способ инъекции лекарственного средства в глазную ткань |
| EP3413851B1 (en) | 2016-02-10 | 2023-09-27 | Clearside Biomedical, Inc. | Packaging |
| JP2019514581A (ja) | 2016-05-02 | 2019-06-06 | クリアサイド バイオメディカル，インコーポレイテッド | 眼の薬物送達のためのシステムおよび方法 |
| IL264764B2 (en) | 2016-08-12 | 2024-02-01 | Clearside Biomedical Inc | Devices and methods for adjusting the insertion depth of a drug administration needle |
| WO2018204515A1 (en) | 2017-05-02 | 2018-11-08 | Georgia Tech Research Corporation | Targeted drug delivery methods using a microneedle |
| IL278899B2 (en) * | 2018-06-04 | 2024-03-01 | Spermvital As | A useful kit for preparing hydrogels |
| CN112969479A (zh) * | 2018-11-06 | 2021-06-15 | 国立癌症中心 | 海藻酸基注射型凝胶体系 |
| CN113423386A (zh) * | 2019-10-01 | 2021-09-21 | 美国倍利年制药有限公司 | 治疗或预防肥胖和体重管理的方法 |
| US20230105586A1 (en) * | 2020-03-26 | 2023-04-06 | Osaka University | Supporting bath for three-dimensional (3d) tissue culture |
| CN114533653B (zh) * | 2020-11-26 | 2023-12-22 | 上海凯茂生物医药有限公司 | 一种人促红素杂合Fc融合蛋白相变型制剂及其制备方法 |
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| US4241099A (en) * | 1979-02-26 | 1980-12-23 | Tiemstra Peter J | Pectin formulations, products and methods having delayed-action acidulants |
| US4789516A (en) * | 1983-04-15 | 1988-12-06 | Damon Biotech, Inc | Production of sustained released system |
| US4690682A (en) * | 1983-04-15 | 1987-09-01 | Damon Biotech, Inc. | Sustained release |
| US4744933A (en) * | 1984-02-15 | 1988-05-17 | Massachusetts Institute Of Technology | Process for encapsulation and encapsulated active material system |
| CA1215922A (en) * | 1984-05-25 | 1986-12-30 | Connaught Laboratories Limited | Microencapsulation of living tissue and cells |
| JPS645460A (en) * | 1987-06-29 | 1989-01-10 | Sanei Kagaku Kogyo Kk | Production of delaying gelatinous material |
| JPH0794583B2 (ja) * | 1989-12-15 | 1995-10-11 | 株式会社大塚製薬工場 | 高含水高分子ゲル |
| IT1245383B (it) * | 1991-03-28 | 1994-09-20 | Eniricerche Spa | Composizione acquosa gelificabile avente tempo di gelificazione ritardato |
| US5711968A (en) * | 1994-07-25 | 1998-01-27 | Alkermes Controlled Therapeutics, Inc. | Composition and method for the controlled release of metal cation-stabilized interferon |
| KR960006730B1 (ko) * | 1993-02-11 | 1996-05-23 | 재단법인한국화학연구소 | 에멀젼 네트웍(emulsion network)을 이용한 약물의 피부 전달체계 |
| GB9708773D0 (en) * | 1997-04-30 | 1997-06-25 | Reckitt & Colmann Prod Ltd | Organic compositions |
-
1998
- 1998-05-18 WO PCT/US1998/010013 patent/WO1998051348A2/en not_active Ceased
- 1998-05-18 CA CA002289196A patent/CA2289196C/en not_active Expired - Fee Related
- 1998-05-18 EP EP98922348A patent/EP0981374B1/en not_active Expired - Lifetime
- 1998-05-18 SK SK1543-99A patent/SK286437B6/sk not_active IP Right Cessation
- 1998-05-18 ES ES98922348T patent/ES2294814T3/es not_active Expired - Lifetime
- 1998-05-18 AU AU74918/98A patent/AU7491898A/en not_active Abandoned
- 1998-05-18 HU HU0003393A patent/HUP0003393A3/hu unknown
- 1998-05-18 KR KR1019997010326A patent/KR20010012374A/ko not_active Ceased
- 1998-05-18 YU YU58599A patent/YU58599A/sh unknown
- 1998-05-18 BR BR9809117-4A patent/BR9809117A/pt not_active Application Discontinuation
- 1998-05-18 DE DE69838750T patent/DE69838750T2/de not_active Expired - Fee Related
- 1998-05-18 JP JP54960298A patent/JP2001525826A/ja not_active Ceased
- 1998-05-18 EA EA199901013A patent/EA199901013A1/ru unknown
- 1998-05-18 PL PL336887A patent/PL199565B1/pl unknown
- 1998-05-18 CZ CZ0396399A patent/CZ299180B6/cs not_active IP Right Cessation
- 1998-05-18 IL IL13281498A patent/IL132814A0/xx unknown
-
1999
- 1999-11-15 NO NO995591A patent/NO995591D0/no not_active Application Discontinuation
- 1999-11-23 BG BG103914A patent/BG64860B1/bg unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CZ396399A3 (cs) | 2000-04-12 |
| ES2294814T3 (es) | 2008-04-01 |
| CA2289196A1 (en) | 1998-11-19 |
| NO995591L (no) | 1999-11-15 |
| HUP0003393A2 (hu) | 2001-02-28 |
| IL132814A0 (en) | 2001-03-19 |
| DE69838750D1 (de) | 2008-01-03 |
| PL199565B1 (pl) | 2008-10-31 |
| CZ299180B6 (cs) | 2008-05-14 |
| BG103914A (en) | 2000-07-31 |
| EA199901013A1 (ru) | 2000-06-26 |
| NO995591D0 (no) | 1999-11-15 |
| SK154399A3 (en) | 2000-07-11 |
| EP0981374A2 (en) | 2000-03-01 |
| EP0981374B1 (en) | 2007-11-21 |
| KR20010012374A (ko) | 2001-02-15 |
| CA2289196C (en) | 2007-08-07 |
| AU7491898A (en) | 1998-12-08 |
| HUP0003393A3 (en) | 2001-03-28 |
| YU58599A (sh) | 2000-12-28 |
| SK286437B6 (sk) | 2008-10-07 |
| JP2001525826A (ja) | 2001-12-11 |
| WO1998051348A2 (en) | 1998-11-19 |
| BG64860B1 (bg) | 2006-07-31 |
| WO1998051348A3 (en) | 1999-02-18 |
| PL336887A1 (en) | 2000-07-17 |
| BR9809117A (pt) | 2000-08-01 |
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| 8339 | Ceased/non-payment of the annual fee |