HUP0003393A2 - Hosszan tartó felszabadulású, késleltetett gélek - Google Patents

Hosszan tartó felszabadulású, késleltetett gélek

Info

Publication number
HUP0003393A2
HUP0003393A2 HU0003393A HUP0003393A HUP0003393A2 HU P0003393 A2 HUP0003393 A2 HU P0003393A2 HU 0003393 A HU0003393 A HU 0003393A HU P0003393 A HUP0003393 A HU P0003393A HU P0003393 A2 HUP0003393 A2 HU P0003393A2
Authority
HU
Hungary
Prior art keywords
ustained
gels
release delayed
sustained release
delayed gels
Prior art date
Application number
HU0003393A
Other languages
English (en)
Inventor
Alice C. Beekman
Merrill Seymour Goldenberg
Jian Hua Gu
Original Assignee
Amgen Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc. filed Critical Amgen Inc.
Publication of HUP0003393A2 publication Critical patent/HUP0003393A2/hu
Publication of HUP0003393A3 publication Critical patent/HUP0003393A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

A jelen találmány alginát késleltetett géleket használó, hosszan tartófelszabadulású készítményekkel és az ezekkel kapcsolatos módszerekkelkapcsolatos. A hosszan tartó felszabadulású, késleltetettgélkészítmény tartalmaz a) egy hidrofil polimert, b) egy biológiailagaktív anyagot és c) legalább egy kötött polivalens fémiont. Ó
HU0003393A 1997-05-16 1998-05-18 Ustained-release delayed gels HUP0003393A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85797397A 1997-05-16 1997-05-16
US91290297A 1997-08-15 1997-08-15

Publications (2)

Publication Number Publication Date
HUP0003393A2 true HUP0003393A2 (hu) 2001-02-28
HUP0003393A3 HUP0003393A3 (en) 2001-03-28

Family

ID=27127437

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0003393A HUP0003393A3 (en) 1997-05-16 1998-05-18 Ustained-release delayed gels

Country Status (18)

Country Link
EP (1) EP0981374B1 (hu)
JP (1) JP2001525826A (hu)
KR (1) KR20010012374A (hu)
AU (1) AU7491898A (hu)
BG (1) BG64860B1 (hu)
BR (1) BR9809117A (hu)
CA (1) CA2289196C (hu)
CZ (1) CZ299180B6 (hu)
DE (1) DE69838750T2 (hu)
EA (1) EA199901013A1 (hu)
ES (1) ES2294814T3 (hu)
HU (1) HUP0003393A3 (hu)
IL (1) IL132814A0 (hu)
NO (1) NO995591L (hu)
PL (1) PL199565B1 (hu)
SK (1) SK286437B6 (hu)
WO (1) WO1998051348A2 (hu)
YU (1) YU58599A (hu)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6432449B1 (en) * 1998-05-18 2002-08-13 Amgen Inc. Biodegradable sustained-release alginate gels
AU2003200609B2 (en) * 1998-05-18 2006-02-23 Amgen Inc. Biodegradable sustained-release alginate gels
JP2000256216A (ja) * 1999-03-04 2000-09-19 Meiji Milk Prod Co Ltd ゲル組成物
US7582311B1 (en) 1999-10-15 2009-09-01 Genentech, Inc. Injection vehicle for polymer-based formulations
US7651703B2 (en) 1999-10-15 2010-01-26 Genentech, Inc. Injection vehicle for polymer-based formulations
WO2001037802A1 (en) * 1999-11-29 2001-05-31 Advanced Research And Technology Institute, Inc. Sustained percutaneous delivery of a biologically active substance
FR2823119B1 (fr) * 2001-04-05 2004-02-20 Seppic Sa Adjuvant d'immunite contenant un cation metallique complexe et vaccin le contenant
MXPA05004299A (es) * 2002-10-25 2005-08-03 Pfizer Prod Inc Formulacion de liberacion prolongada de agentes activos arilheterociclicos en forma de suspension.
JP5336180B2 (ja) * 2005-05-23 2013-11-06 ナチュラル オータナティブス インターナショナル β−アラニンの徐放のための組成物及び方法
US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
JP5107585B2 (ja) * 2007-01-29 2012-12-26 株式会社 メドレックス 低温充填ゼリー組成物とその製造方法
EP1985286A1 (en) * 2007-04-24 2008-10-29 Biocompatibles UK Limited Microspheres for treatment of brain tumours
CN104758118B (zh) 2010-10-15 2018-04-06 科尼尔赛德生物医学公司 用于进入眼睛的装置
CN104884049A (zh) 2012-11-08 2015-09-02 克莱尔塞德生物医学股份有限公司 用于在人类受试者中治疗眼部疾病的方法和装置
EP4378444A2 (en) 2013-05-03 2024-06-05 Clearside Biomedical, Inc. Apparatus and methods for ocular injection
US10010447B2 (en) 2013-12-18 2018-07-03 Novartis Ag Systems and methods for subretinal delivery of therapeutic agents
JP2017524419A (ja) 2014-06-20 2017-08-31 クリアサイド バイオメディカル，インコーポレイテッド 薬剤送達のための挿入深さを制御するための可変径カニューレ及び方法
EP3413851B1 (en) 2016-02-10 2023-09-27 Clearside Biomedical, Inc. Packaging
CA3062845A1 (en) 2016-05-02 2017-11-09 Clearside Biomedical, Inc. Systems and methods for ocular drug delivery
US10973681B2 (en) 2016-08-12 2021-04-13 Clearside Biomedical, Inc. Devices and methods for adjusting the insertion depth of a needle for medicament delivery
US11957123B2 (en) * 2018-06-04 2024-04-16 Spermvital As Functionalized kit for preparing hydrogels
JP7312822B2 (ja) 2018-11-06 2023-07-21 ナショナル キャンサー センター 注入型ヒドロゲルシステムおよび病変の標識方法
WO2021067076A1 (en) * 2019-10-01 2021-04-08 Brillian Pharma Inc. Methods for treating or preventing obesity and body weight management
CN114533653B (zh) * 2020-11-26 2023-12-22 上海凯茂生物医药有限公司 一种人促红素杂合Fc融合蛋白相变型制剂及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5416979B2 (hu) * 1972-01-08 1979-06-26
US4241099A (en) * 1979-02-26 1980-12-23 Tiemstra Peter J Pectin formulations, products and methods having delayed-action acidulants
US4789516A (en) * 1983-04-15 1988-12-06 Damon Biotech, Inc Production of sustained released system
US4690682A (en) * 1983-04-15 1987-09-01 Damon Biotech, Inc. Sustained release
US4744933A (en) * 1984-02-15 1988-05-17 Massachusetts Institute Of Technology Process for encapsulation and encapsulated active material system
CA1215922A (en) * 1984-05-25 1986-12-30 Connaught Laboratories Limited Microencapsulation of living tissue and cells
JPS645460A (en) * 1987-06-29 1989-01-10 Sanei Kagaku Kogyo Kk Production of delaying gelatinous material
JPH0794583B2 (ja) * 1989-12-15 1995-10-11 株式会社大塚製薬工場 高含水高分子ゲル
IT1245383B (it) * 1991-03-28 1994-09-20 Eniricerche Spa Composizione acquosa gelificabile avente tempo di gelificazione ritardato
US5711968A (en) * 1994-07-25 1998-01-27 Alkermes Controlled Therapeutics, Inc. Composition and method for the controlled release of metal cation-stabilized interferon
KR960006730B1 (ko) * 1993-02-11 1996-05-23 재단법인한국화학연구소 에멀젼 네트웍(emulsion network)을 이용한 약물의 피부 전달체계
GB9708773D0 (en) * 1997-04-30 1997-06-25 Reckitt & Colmann Prod Ltd Organic compositions

Also Published As

Publication number Publication date
PL199565B1 (pl) 2008-10-31
IL132814A0 (en) 2001-03-19
EA199901013A1 (ru) 2000-06-26
KR20010012374A (ko) 2001-02-15
DE69838750D1 (de) 2008-01-03
NO995591D0 (no) 1999-11-15
PL336887A1 (en) 2000-07-17
AU7491898A (en) 1998-12-08
BR9809117A (pt) 2000-08-01
DE69838750T2 (de) 2008-10-30
SK286437B6 (sk) 2008-10-07
CZ299180B6 (cs) 2008-05-14
JP2001525826A (ja) 2001-12-11
CZ396399A3 (cs) 2000-04-12
HUP0003393A3 (en) 2001-03-28
YU58599A (sh) 2000-12-28
BG103914A (en) 2000-07-31
NO995591L (no) 1999-11-15
CA2289196C (en) 2007-08-07
WO1998051348A2 (en) 1998-11-19
ES2294814T3 (es) 2008-04-01
BG64860B1 (bg) 2006-07-31
SK154399A3 (en) 2000-07-11
EP0981374B1 (en) 2007-11-21
EP0981374A2 (en) 2000-03-01
WO1998051348A3 (en) 1999-02-18
CA2289196A1 (en) 1998-11-19

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees