FR2779438B1 - Gel stable, son procede de preparation, et compositions pharmaceutiques le comprenant - Google Patents

Gel stable, son procede de preparation, et compositions pharmaceutiques le comprenant

Info

Publication number
FR2779438B1
FR2779438B1 FR9806958A FR9806958A FR2779438B1 FR 2779438 B1 FR2779438 B1 FR 2779438B1 FR 9806958 A FR9806958 A FR 9806958A FR 9806958 A FR9806958 A FR 9806958A FR 2779438 B1 FR2779438 B1 FR 2779438B1
Authority
FR
France
Prior art keywords
preparation
same
pharmaceutical compositions
stable gel
gel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9806958A
Other languages
English (en)
Other versions
FR2779438A1 (fr
Inventor
Jean Marc Aiache
Pascale Gauthier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to FR9806958A priority Critical patent/FR2779438B1/fr
Priority to US09/204,089 priority patent/US6187323B1/en
Priority to AU39513/99A priority patent/AU3951399A/en
Priority to AT99922436T priority patent/ATE274900T1/de
Priority to DE69919863T priority patent/DE69919863T8/de
Priority to ES99922436T priority patent/ES2228044T3/es
Priority to PCT/IB1999/001068 priority patent/WO1999062497A1/fr
Priority to EP99922436A priority patent/EP1083880B1/fr
Publication of FR2779438A1 publication Critical patent/FR2779438A1/fr
Application granted granted Critical
Publication of FR2779438B1 publication Critical patent/FR2779438B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/042—Gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
    • C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
    • C08J3/075—Macromolecular gels

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dispersion Chemistry (AREA)
  • Birds (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
FR9806958A 1998-06-03 1998-06-03 Gel stable, son procede de preparation, et compositions pharmaceutiques le comprenant Expired - Fee Related FR2779438B1 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
FR9806958A FR2779438B1 (fr) 1998-06-03 1998-06-03 Gel stable, son procede de preparation, et compositions pharmaceutiques le comprenant
US09/204,089 US6187323B1 (en) 1998-06-03 1998-12-03 Stable gel mixture in the form of a mixture of oleogel and aqueous gel, process for its preparation, pharmaceutical and cosmetic compositions comprising it, and use of the pharmaceutical compositions
AT99922436T ATE274900T1 (de) 1998-06-03 1999-06-03 Stabilgelmischung in form einer mischung eines öligen gels und eines wässrigen gels
DE69919863T DE69919863T8 (de) 1998-06-03 1999-06-03 Stabilgelmischung in form einer mischung eines öligen gels und eines wässrigen gels
AU39513/99A AU3951399A (en) 1998-06-03 1999-06-03 Stable gel mixture in the form of a mixture of oleogel and aqueous gel
ES99922436T ES2228044T3 (es) 1998-06-03 1999-06-03 Mezcla de gel estable en forma de una mezcla de oleogel y gel acuoso.
PCT/IB1999/001068 WO1999062497A1 (fr) 1998-06-03 1999-06-03 Melange de gels stable constitue d'un oleogel et d'un gel aqueux
EP99922436A EP1083880B1 (fr) 1998-06-03 1999-06-03 Melange de gels stable constitue d'un oleogel et d'un gel aqueux

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9806958A FR2779438B1 (fr) 1998-06-03 1998-06-03 Gel stable, son procede de preparation, et compositions pharmaceutiques le comprenant

Publications (2)

Publication Number Publication Date
FR2779438A1 FR2779438A1 (fr) 1999-12-10
FR2779438B1 true FR2779438B1 (fr) 2004-12-24

Family

ID=9526967

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9806958A Expired - Fee Related FR2779438B1 (fr) 1998-06-03 1998-06-03 Gel stable, son procede de preparation, et compositions pharmaceutiques le comprenant

Country Status (2)

Country Link
US (1) US6187323B1 (fr)
FR (1) FR2779438B1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108712863A (zh) * 2016-03-30 2018-10-26 陶氏环球技术有限责任公司 乙基纤维素油凝胶分散液

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7029694B2 (en) * 2000-04-26 2006-04-18 Watson Laboratories, Inc. Compositions and methods for transdermal oxybutynin therapy
US7179483B2 (en) * 2000-04-26 2007-02-20 Watson Pharmaceuticals, Inc. Compositions and methods for transdermal oxybutynin therapy
MXPA02010542A (es) * 2000-04-26 2003-10-14 Watson Pharmaceuticals Inc Minimizacion de experiencias adversas asociadas con la terapia con oxibutinina.
EP1213025A1 (fr) * 2000-12-06 2002-06-12 Laboratoires Serobiologiques(Societe Anonyme) Composition cosmétique et/ou dermopharmaceutique conténant un extrait obtenu à partir de feuilles d'Argania spinosa
DE102004030044A1 (de) * 2004-06-22 2006-01-12 Birken Gmbh Triterpenhaltiger Oleogelbildner, triterpenhaltiges Oleogel und Verfahren zur Herstellung eines triterpenhaltigen Oleogels
US20060140820A1 (en) 2004-12-28 2006-06-29 Udo Mattern Use of a container of an inorganic additive containing plastic material
WO2008021666A2 (fr) * 2006-08-18 2008-02-21 Morton Grove Pharmaceuticals, Inc. Compositions stables de lévétiracétam et procédés
ZA200902902B (en) 2006-10-04 2010-07-28 M & P Patent Aktinegesellschaf Controlled release delivery system for nasal application of neurotransmitters
GB2445539A (en) * 2006-12-29 2008-07-16 Ardana Bioscience Ltd Bigel composition
WO2008091588A1 (fr) 2007-01-22 2008-07-31 Targacept, Inc. Administration intranasale, buccale ou sublinguale d'analogues de métanicotine
CN102510725B (zh) 2009-06-12 2014-12-03 马斯公司 油的聚合物凝胶化
GB2485421B (en) 2010-11-15 2016-05-25 Mars Inc Dough products exhibiting reduced oil migration
US9168309B2 (en) 2010-12-01 2015-10-27 Omnis Biotechnology Inc. Thixotropic compositions
JP6267633B2 (ja) 2011-05-06 2018-01-24 オルガノバランス メディカル アーゲー 新規な乳酸菌及びそれを含有する組成物
AR086400A1 (es) 2011-05-13 2013-12-11 Trimel Pharmaceuticals Corp Formulaciones en gel intranasal de testosterona en dosis de menor potencia y uso de las mismas para el tratamiento de la anorgasmia o el trastorno de deseo sexual hipoactivo
US9757388B2 (en) 2011-05-13 2017-09-12 Acerus Pharmaceuticals Srl Intranasal methods of treating women for anorgasmia with 0.6% and 0.72% testosterone gels
US20130045958A1 (en) 2011-05-13 2013-02-21 Trimel Pharmaceuticals Corporation Intranasal 0.15% and 0.24% testosterone gel formulations and use thereof for treating anorgasmia or hypoactive sexual desire disorder
CA2833937C (fr) 2011-05-16 2022-04-05 Organobalance Medical Ag Souches de lactobacilles, compositions comprenant ces souches et utilisation des souches pour prevenir ou traiter des maladies provoqueespar le streptocoque pyogene
PT2782584T (pt) 2011-11-23 2021-09-02 Therapeuticsmd Inc Preparações e terapias de substituição para hormonoterapias naturais combinadas
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
KR102308971B1 (ko) 2012-06-28 2021-10-07 뉴트리션 ＆ 바이오사이언시즈 유에스에이 1, 엘엘씨 식용가능한 올레오겔의 제조 방법
CA2884068C (fr) 2012-09-28 2021-04-27 Mars, Incorporated Chocolat resistant a la chaleur
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
FR3002449B1 (fr) * 2013-02-25 2015-04-03 Oreal Composition cosmetique de type gel
FR3002444B1 (fr) 2013-02-25 2015-03-13 Oreal Composition cosmetique de type gel
FR3002448B1 (fr) * 2013-02-25 2015-04-03 Oreal Composition cosmetique de type gel
US11744838B2 (en) 2013-03-15 2023-09-05 Acerus Biopharma Inc. Methods of treating hypogonadism with transnasal testosterone bio-adhesive gel formulations in male with allergic rhinitis, and methods for preventing an allergic rhinitis event
KR20160002929A (ko) * 2013-04-16 2016-01-08 다우 글로벌 테크놀로지스 엘엘씨 저지방 라미네이트된 도우 및 패스트리
US9655376B2 (en) 2013-05-31 2017-05-23 Dow Global Technologies Llc Process for preparing an oleogel
AR100562A1 (es) 2014-05-22 2016-10-12 Therapeuticsmd Inc Composición farmacéutica de estradiol y progesterona para terapia de reemplazo hormonal
WO2016018993A1 (fr) 2014-07-29 2016-02-04 Therapeuticsmd, Inc. Crème transdermique
EP3185843B1 (fr) * 2014-08-28 2021-08-11 L'Oréal Composition gel/gel comprenant un filtre uv
FR3025100B1 (fr) 2014-08-28 2016-12-09 Oreal Composition cosmetique de type gel a tenue amelioree
GB201419257D0 (en) * 2014-10-29 2014-12-10 Jagotec Ag Pharmaceutical compositions
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
BR122023025444A2 (pt) * 2016-01-07 2024-02-20 Viramal Limited Composição de gel estável, e, método de preparação de uma composição em gel estável
CN108777972A (zh) * 2016-03-30 2018-11-09 陶氏环球技术有限责任公司 制备油凝胶的方法
CA3020153A1 (fr) 2016-04-01 2017-10-05 Therapeuticsmd, Inc. Composition pharmaceutique d'hormone steroide
WO2017173044A1 (fr) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Compositions d'hormones stéroïdes dans des huiles à chaîne moyenne
FR3063899B1 (fr) * 2017-03-17 2019-04-19 Capsum Compositions comprenant une phase grasse et une phase aqueuse sous forme de spheres solides
CN107296260A (zh) * 2017-05-27 2017-10-27 华中农业大学 一种高膳食纤维油凝胶的制备方法
WO2019093780A1 (fr) * 2017-11-10 2019-05-16 (주)아모레퍼시픽 Composition cosmétique de type vigel
US11337919B2 (en) 2017-12-18 2022-05-24 Tris Pharma, Inc. Modified release drug powder composition comprising gastro-retentive RAFT forming systems having trigger pulse drug release
EP3737353A1 (fr) 2017-12-18 2020-11-18 Tris Pharma, Inc. Compositions pharmaceutiques de ghb comprenant un système de formation de réseau polymère interpénétrant flottant
US11337920B2 (en) 2017-12-18 2022-05-24 Tris Pharma, Inc. Pharmaceutical composition comprising GHB gastro-retentive raft forming systems having trigger pulse drug release
EP3727336A1 (fr) 2017-12-20 2020-10-28 3M Innovative Properties Company Compositions orales et procédés d'utilisation
JP7358353B2 (ja) 2018-01-04 2023-10-10 アムリット・リサーチ・リミテッド ベツリン含有白樺樹皮抽出物およびその製剤
WO2020084548A1 (fr) 2018-10-26 2020-04-30 Viramal Limited Composition de gel mucoadhésif
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations
EP3922235A1 (fr) * 2020-06-11 2021-12-15 Viramal Limited Gel hydroalcoolique et procédé de fabrication d'un tel gel
CN113383947B (zh) * 2021-06-21 2022-09-27 江南大学 一种制备相变可调的乳液凝胶型脂肪替代物的方法及应用
CN115429703B (zh) * 2022-10-24 2023-09-22 中国热带农业科学院农产品加工研究所 双凝胶组合物及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2635463A1 (fr) * 1988-08-19 1990-02-23 Veprol Composition pharmaceutique comportant un principe actif peu soluble dans l'eau et au moins un glyceride gelifie par au moins un polymere cellulosique
GB9207988D0 (en) * 1992-04-10 1992-05-27 Smithkline Beecham Plc Topical composition
KR970064620A (ko) * 1996-03-05 1997-10-13 임성기 사이클로스포린-함유 외용약제 조성물

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108712863A (zh) * 2016-03-30 2018-10-26 陶氏环球技术有限责任公司 乙基纤维素油凝胶分散液

Also Published As

Publication number Publication date
FR2779438A1 (fr) 1999-12-10
US6187323B1 (en) 2001-02-13

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Effective date: 20090228