ATE332918T1 - Neoglycoproteine - Google Patents
NeoglycoproteineInfo
- Publication number
- ATE332918T1 ATE332918T1 AT98924125T AT98924125T ATE332918T1 AT E332918 T1 ATE332918 T1 AT E332918T1 AT 98924125 T AT98924125 T AT 98924125T AT 98924125 T AT98924125 T AT 98924125T AT E332918 T1 ATE332918 T1 AT E332918T1
- Authority
- AT
- Austria
- Prior art keywords
- conjugates
- polyamide
- neoglycoproteins
- group
- macromolecular
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
- B01J20/26—Synthetic macromolecular compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97810244 | 1997-04-18 | ||
| EP97810243 | 1997-04-18 | ||
| GBGB9802450.8A GB9802450D0 (en) | 1998-02-05 | 1998-02-05 | Organic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE332918T1 true ATE332918T1 (de) | 2006-08-15 |
Family
ID=27238761
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98924125T ATE332918T1 (de) | 1997-04-18 | 1998-04-16 | Neoglycoproteine |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US6399071B1 (de) |
| EP (1) | EP0970114B1 (de) |
| JP (1) | JP3474583B2 (de) |
| CN (1) | CN1185253C (de) |
| AT (1) | ATE332918T1 (de) |
| AU (1) | AU733282B2 (de) |
| CA (1) | CA2284729A1 (de) |
| DE (1) | DE69835201T2 (de) |
| ES (1) | ES2268776T3 (de) |
| IL (1) | IL132156A0 (de) |
| PT (1) | PT970114E (de) |
| WO (1) | WO1998047915A1 (de) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU733282B2 (en) * | 1997-04-18 | 2001-05-10 | Novartis Ag | Neoglycoproteins |
| DE69927369T2 (de) | 1998-04-15 | 2006-06-22 | Mayo Foundation For Medical Education And Research, Rochester | Hemmung xenoreaktiver antikörper |
| US6458953B1 (en) | 1998-12-09 | 2002-10-01 | La Jolla Pharmaceutical Company | Valency platform molecules comprising carbamate linkages |
| US6399578B1 (en) * | 1998-12-09 | 2002-06-04 | La Jolla Pharmaceutical Company | Conjugates comprising galactose α1,3 galactosyl epitopes and methods of using same |
| CA2353620A1 (en) * | 1998-12-09 | 2000-06-15 | La Jolla Pharmaceutical Company | Methods and formulations for reducing circulating antibodies |
| AU4565000A (en) | 1999-05-10 | 2000-11-21 | Novartis Ag | Organic compounds |
| BRPI0316018B8 (pt) | 2002-11-12 | 2021-05-25 | Brigham & Womens Hospital Inc | vacina polissacarídica para infecções estafilocócicas |
| CN100365007C (zh) * | 2003-09-01 | 2008-01-30 | 北京大学 | 三糖和五糖寡糖抗原，它们的合成方法以及在制备抑制排斥反应的药物中的用途 |
| AU2005295708A1 (en) * | 2004-10-13 | 2006-04-27 | Relypsa, Inc. | Pharmaceutical compositions comprising a toxin-binding oligosaccharide and a polymeric particle |
| US20060078534A1 (en) * | 2004-10-13 | 2006-04-13 | Dominique Charmot | Toxin binding compositions |
| GB0502095D0 (en) * | 2005-02-01 | 2005-03-09 | Chiron Srl | Conjugation of streptococcal capsular saccharides |
| US7960139B2 (en) | 2007-03-23 | 2011-06-14 | Academia Sinica | Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells |
| JP5986745B2 (ja) | 2008-07-15 | 2016-09-06 | アカデミア シニカＡｃａｄｅｍｉａ Ｓｉｎｉｃａ | Ｐｔｆｅ様のアルミニウム・コート・ガラススライド上のグリカンアレイおよび関連する方法 |
| BRPI0916365A2 (pt) * | 2008-07-21 | 2018-05-02 | Brigham & Womens Hospital Inc | métodos e composições relacionados aos oligossacarídeos de glicosina beta-1,6 sintéticos |
| US11377485B2 (en) | 2009-12-02 | 2022-07-05 | Academia Sinica | Methods for modifying human antibodies by glycan engineering |
| US10087236B2 (en) | 2009-12-02 | 2018-10-02 | Academia Sinica | Methods for modifying human antibodies by glycan engineering |
| WO2011130332A1 (en) | 2010-04-12 | 2011-10-20 | Academia Sinica | Glycan arrays for high throughput screening of viruses |
| US10130714B2 (en) | 2012-04-14 | 2018-11-20 | Academia Sinica | Enhanced anti-influenza agents conjugated with anti-inflammatory activity |
| AU2013306098A1 (en) | 2012-08-18 | 2015-02-12 | Academia Sinica | Cell-permeable probes for identification and imaging of sialidases |
| US10086054B2 (en) * | 2013-06-26 | 2018-10-02 | Academia Sinica | RM2 antigens and use thereof |
| EP3013347B1 (de) | 2013-06-27 | 2019-12-11 | Academia Sinica | Glykankonjugate und verwendung davon |
| WO2015007326A1 (en) | 2013-07-18 | 2015-01-22 | Institut D'investigació Biomèdica De Bellvitge (Idibell) | Agents comprising a terminal alpha-galactosyl moiety for use in prevention and/or treatment of inflammatory diseases |
| CN105682666B (zh) | 2013-09-06 | 2021-06-01 | 中央研究院 | 使用醣脂激活人类iNKT细胞 |
| US10150818B2 (en) | 2014-01-16 | 2018-12-11 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
| US9982041B2 (en) | 2014-01-16 | 2018-05-29 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
| KR20160132034A (ko) | 2014-03-13 | 2016-11-16 | 우니페르시테트 바젤 | 미엘린-관련 당단백질에 대한 IgM 항체와 결합하는 탄수화물 리간드 |
| TWI687428B (zh) | 2014-03-27 | 2020-03-11 | 中央研究院 | 反應性標記化合物及其用途 |
| WO2015175972A2 (en) * | 2014-05-15 | 2015-11-19 | Mayo Foundation For Medical Education And Research | Solution target for cyclotron production of radiometals |
| EP3149161B1 (de) | 2014-05-27 | 2021-07-28 | Academia Sinica | Fucosidase aus bacteroiden und verfahren damit |
| AU2015267045B2 (en) | 2014-05-27 | 2021-02-25 | Academia Sinica | Anti-HER2 glycoantibodies and uses thereof |
| US10118969B2 (en) | 2014-05-27 | 2018-11-06 | Academia Sinica | Compositions and methods relating to universal glycoforms for enhanced antibody efficacy |
| TWI732738B (zh) | 2014-05-28 | 2021-07-11 | 中央研究院 | 抗TNF-α醣抗體及其用途 |
| EP2987503A1 (de) * | 2014-08-22 | 2016-02-24 | Institut d'Investigació Biomèdica de Bellvitge (IDIBELL) | Verfahren und Reagenzien zur Prävention und/oder Behandlung von Infektionen |
| WO2016040369A2 (en) | 2014-09-08 | 2016-03-17 | Academia Sinica | HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS |
| US9975965B2 (en) | 2015-01-16 | 2018-05-22 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
| US10495645B2 (en) | 2015-01-16 | 2019-12-03 | Academia Sinica | Cancer markers and methods of use thereof |
| EP3248005B1 (de) | 2015-01-24 | 2020-12-09 | Academia Sinica | Neuartige glycankonjugate und verfahren zur verwendung davon |
| JP6849667B2 (ja) | 2015-09-16 | 2021-03-24 | ウニヴェルズィテート バーゼル | スフィンゴ糖脂質の糖鎖エピトープに対する抗体に結合する炭水化物リガンド |
| TW201808978A (zh) | 2016-03-08 | 2018-03-16 | 中央研究院 | N-聚醣及其陣列之模組化合成方法 |
| JP7213549B2 (ja) | 2016-08-22 | 2023-01-27 | シーエイチオー ファーマ インコーポレイテッド | 抗体、結合性断片、および使用の方法 |
| JP2020514414A (ja) * | 2017-03-15 | 2020-05-21 | ポリニューロン ファーマシューティカルズ アーゲー | 糖結合タンパク質を隔離する糖ポリマー |
| EP3964235A1 (de) | 2020-09-08 | 2022-03-09 | RemAb Therapeutics SL | Glycokonjugate und deren medizinische verwendungen |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5149425A (en) * | 1988-11-09 | 1992-09-22 | Chembiomed, Ltd. | Affinity supports for hemoperfusion |
| US5286846A (en) * | 1991-06-14 | 1994-02-15 | The Government Of The United States Of America As Represented By The Dept. Of Health And Human Services | Amino acid derivative and bromoacetyl modified peptides for the preparation of synthetic peptide polymers, conjugated peptides, and cyclic peptides |
| DE69232928D1 (de) | 1991-08-23 | 2003-03-27 | Alberta Res Council | Verfahren und zusammensetzungen zur verhinderung der antikörper-vermittelten abstossung von xenogenen transplantaten |
| EP0601417A3 (de) * | 1992-12-11 | 1998-07-01 | Hoechst Aktiengesellschaft | Physiologisch verträglicher und physiologisch abbaubarer, Kohlenhydratrezeptorblocker auf Polymerbasis, ein Verfahren zu seiner Herstellung und seine Verwendung |
| FR2727117A1 (fr) | 1994-11-18 | 1996-05-24 | Geffard Michel | Utilisation de conjugues de la polylysine pour la preparation de medicaments utiles dans le traitement des maladies neurodegeneratives et des affections degeneratives a caractere autoimmun |
| EP0866802A1 (de) * | 1995-11-21 | 1998-09-30 | Novartis AG | Multivalente polymere, deren herstellung und verwendung zur herstellung von biologisch aktiven verbindungen |
| AU733282B2 (en) * | 1997-04-18 | 2001-05-10 | Novartis Ag | Neoglycoproteins |
-
1998
- 1998-04-16 AU AU76439/98A patent/AU733282B2/en not_active Ceased
- 1998-04-16 WO PCT/EP1998/002227 patent/WO1998047915A1/en active IP Right Grant
- 1998-04-16 PT PT98924125T patent/PT970114E/pt unknown
- 1998-04-16 IL IL13215698A patent/IL132156A0/xx unknown
- 1998-04-16 CN CNB988042835A patent/CN1185253C/zh not_active Expired - Fee Related
- 1998-04-16 CA CA002284729A patent/CA2284729A1/en not_active Abandoned
- 1998-04-16 DE DE69835201T patent/DE69835201T2/de not_active Expired - Fee Related
- 1998-04-16 EP EP98924125A patent/EP0970114B1/de not_active Expired - Lifetime
- 1998-04-16 AT AT98924125T patent/ATE332918T1/de not_active IP Right Cessation
- 1998-04-16 ES ES98924125T patent/ES2268776T3/es not_active Expired - Lifetime
- 1998-04-16 US US09/403,111 patent/US6399071B1/en not_active Expired - Fee Related
- 1998-04-16 JP JP54496998A patent/JP3474583B2/ja not_active Expired - Fee Related
-
2002
- 2002-04-16 US US10/123,396 patent/US6723831B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1185253C (zh) | 2005-01-19 |
| DE69835201D1 (en) | 2006-08-24 |
| US20020164347A1 (en) | 2002-11-07 |
| IL132156A0 (en) | 2001-03-19 |
| AU7643998A (en) | 1998-11-13 |
| US6723831B2 (en) | 2004-04-20 |
| JP2001500528A (ja) | 2001-01-16 |
| EP0970114A1 (de) | 2000-01-12 |
| AU733282B2 (en) | 2001-05-10 |
| JP3474583B2 (ja) | 2003-12-08 |
| PT970114E (pt) | 2006-12-29 |
| WO1998047915A1 (en) | 1998-10-29 |
| US6399071B1 (en) | 2002-06-04 |
| CA2284729A1 (en) | 1998-10-29 |
| CN1252807A (zh) | 2000-05-10 |
| DE69835201T2 (de) | 2007-06-14 |
| EP0970114B1 (de) | 2006-07-12 |
| ES2268776T3 (es) | 2007-03-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0970114 Country of ref document: EP |
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| REN | Ceased due to non-payment of the annual fee |