BG64860B1 - Фармацевтичен състав с продължително освобождаване и неговото използване - Google Patents

Фармацевтичен състав с продължително освобождаване и неговото използване Download PDF

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Publication number
BG64860B1
BG64860B1 BG103914A BG10391499A BG64860B1 BG 64860 B1 BG64860 B1 BG 64860B1 BG 103914 A BG103914 A BG 103914A BG 10391499 A BG10391499 A BG 10391499A BG 64860 B1 BG64860 B1 BG 64860B1
Authority
BG
Bulgaria
Prior art keywords
pharmaceutical composition
composition according
protein
alginate
leptin
Prior art date
Application number
BG103914A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG103914A (en
Inventor
Merrill Goldenberg
Alice Beekman
Jian Gu
Original Assignee
Amgen Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc. filed Critical Amgen Inc.
Publication of BG103914A publication Critical patent/BG103914A/xx
Publication of BG64860B1 publication Critical patent/BG64860B1/bg

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
BG103914A 1997-05-16 1999-11-23 Фармацевтичен състав с продължително освобождаване и неговото използване BG64860B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85797397A 1997-05-16 1997-05-16
US91290297A 1997-08-15 1997-08-15

Publications (2)

Publication Number Publication Date
BG103914A BG103914A (en) 2000-07-31
BG64860B1 true BG64860B1 (bg) 2006-07-31

Family

ID=27127437

Family Applications (1)

Application Number Title Priority Date Filing Date
BG103914A BG64860B1 (bg) 1997-05-16 1999-11-23 Фармацевтичен състав с продължително освобождаване и неговото използване

Country Status (18)

Country Link
EP (1) EP0981374B1 (enExample)
JP (1) JP2001525826A (enExample)
KR (1) KR20010012374A (enExample)
AU (1) AU7491898A (enExample)
BG (1) BG64860B1 (enExample)
BR (1) BR9809117A (enExample)
CA (1) CA2289196C (enExample)
CZ (1) CZ299180B6 (enExample)
DE (1) DE69838750T2 (enExample)
EA (1) EA199901013A1 (enExample)
ES (1) ES2294814T3 (enExample)
HU (1) HUP0003393A3 (enExample)
IL (1) IL132814A0 (enExample)
NO (1) NO995591D0 (enExample)
PL (1) PL199565B1 (enExample)
SK (1) SK286437B6 (enExample)
WO (1) WO1998051348A2 (enExample)
YU (1) YU58599A (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003200609B2 (en) * 1998-05-18 2006-02-23 Amgen Inc. Biodegradable sustained-release alginate gels
US6432449B1 (en) * 1998-05-18 2002-08-13 Amgen Inc. Biodegradable sustained-release alginate gels
JP2000256216A (ja) * 1999-03-04 2000-09-19 Meiji Milk Prod Co Ltd ゲル組成物
US7582311B1 (en) 1999-10-15 2009-09-01 Genentech, Inc. Injection vehicle for polymer-based formulations
US7651703B2 (en) 1999-10-15 2010-01-26 Genentech, Inc. Injection vehicle for polymer-based formulations
CA2396431A1 (en) * 1999-11-29 2001-05-31 Advanced Research And Technology Institute, Inc. Sustained percutaneous delivery of a biologically active substance
FR2823119B1 (fr) * 2001-04-05 2004-02-20 Seppic Sa Adjuvant d'immunite contenant un cation metallique complexe et vaccin le contenant
KR20050071611A (ko) * 2002-10-25 2005-07-07 화이자 프로덕츠 인코포레이티드 현탁액 형태의 아릴헤테로환 활성제의 저장 제형
WO2007073398A2 (en) * 2005-05-23 2007-06-28 Natural Alternatives International Compositions and methods for the sustained release of beta-alanine
US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
JP5107585B2 (ja) * 2007-01-29 2012-12-26 株式会社 メドレックス 低温充填ゼリー組成物とその製造方法
EP1985286A1 (en) * 2007-04-24 2008-10-29 Biocompatibles UK Limited Microspheres for treatment of brain tumours
BR112013009205A2 (pt) 2010-10-15 2016-07-26 Iscience Interventional Corp dispositivo para colocação na esclera de um olho, método para acessar o espaço supracoroidal de um olho, para acessar o espaço subretinal de um olho e para colocar um orifício dentro de um trato escleral em um olho.
CA3240136A1 (en) 2012-11-08 2014-05-15 Clearside Biomedical, Inc. Methods and devices for the treatment of ocular diseases in human subjects
SG10201702674PA (en) 2013-05-03 2017-06-29 Clearside Biomedical Inc Apparatus and methods for ocular injection
US10010447B2 (en) 2013-12-18 2018-07-03 Novartis Ag Systems and methods for subretinal delivery of therapeutic agents
RU2710491C2 (ru) 2014-06-20 2019-12-26 Клиасайд Байомедикал, Инк. Устройство для инъекции лекарственного средства в глазную ткань и способ инъекции лекарственного средства в глазную ткань
EP3413851B1 (en) 2016-02-10 2023-09-27 Clearside Biomedical, Inc. Packaging
JP2019514581A (ja) 2016-05-02 2019-06-06 クリアサイド バイオメディカル,インコーポレイテッド 眼の薬物送達のためのシステムおよび方法
IL264764B2 (en) 2016-08-12 2024-02-01 Clearside Biomedical Inc Devices and methods for adjusting the insertion depth of a drug administration needle
WO2018204515A1 (en) 2017-05-02 2018-11-08 Georgia Tech Research Corporation Targeted drug delivery methods using a microneedle
IL278899B2 (en) * 2018-06-04 2024-03-01 Spermvital As A useful kit for preparing hydrogels
CN112969479A (zh) * 2018-11-06 2021-06-15 国立癌症中心 海藻酸基注射型凝胶体系
CN113423386A (zh) * 2019-10-01 2021-09-21 美国倍利年制药有限公司 治疗或预防肥胖和体重管理的方法
US20230105586A1 (en) * 2020-03-26 2023-04-06 Osaka University Supporting bath for three-dimensional (3d) tissue culture
CN114533653B (zh) * 2020-11-26 2023-12-22 上海凯茂生物医药有限公司 一种人促红素杂合Fc融合蛋白相变型制剂及其制备方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1388580A (en) * 1972-01-08 1975-03-26 Toray Industries Hydrogels
US4690682A (en) * 1983-04-15 1987-09-01 Damon Biotech, Inc. Sustained release
US4744933A (en) * 1984-02-15 1988-05-17 Massachusetts Institute Of Technology Process for encapsulation and encapsulated active material system
US4789550A (en) * 1984-05-25 1988-12-06 Connaught Laboratories Limited Microcapsule composition suitable for cardiovascular injection
US4789516A (en) * 1983-04-15 1988-12-06 Damon Biotech, Inc Production of sustained released system

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4241099A (en) * 1979-02-26 1980-12-23 Tiemstra Peter J Pectin formulations, products and methods having delayed-action acidulants
JPS645460A (en) * 1987-06-29 1989-01-10 Sanei Kagaku Kogyo Kk Production of delaying gelatinous material
JPH0794583B2 (ja) * 1989-12-15 1995-10-11 株式会社大塚製薬工場 高含水高分子ゲル
IT1245383B (it) * 1991-03-28 1994-09-20 Eniricerche Spa Composizione acquosa gelificabile avente tempo di gelificazione ritardato
US5711968A (en) * 1994-07-25 1998-01-27 Alkermes Controlled Therapeutics, Inc. Composition and method for the controlled release of metal cation-stabilized interferon
KR960006730B1 (ko) * 1993-02-11 1996-05-23 재단법인한국화학연구소 에멀젼 네트웍(emulsion network)을 이용한 약물의 피부 전달체계
GB9708773D0 (en) * 1997-04-30 1997-06-25 Reckitt & Colmann Prod Ltd Organic compositions

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1388580A (en) * 1972-01-08 1975-03-26 Toray Industries Hydrogels
US4690682A (en) * 1983-04-15 1987-09-01 Damon Biotech, Inc. Sustained release
US4789516A (en) * 1983-04-15 1988-12-06 Damon Biotech, Inc Production of sustained released system
US4744933A (en) * 1984-02-15 1988-05-17 Massachusetts Institute Of Technology Process for encapsulation and encapsulated active material system
US4789550A (en) * 1984-05-25 1988-12-06 Connaught Laboratories Limited Microcapsule composition suitable for cardiovascular injection

Also Published As

Publication number Publication date
CZ396399A3 (cs) 2000-04-12
ES2294814T3 (es) 2008-04-01
CA2289196A1 (en) 1998-11-19
NO995591L (no) 1999-11-15
HUP0003393A2 (hu) 2001-02-28
IL132814A0 (en) 2001-03-19
DE69838750D1 (de) 2008-01-03
PL199565B1 (pl) 2008-10-31
CZ299180B6 (cs) 2008-05-14
BG103914A (en) 2000-07-31
EA199901013A1 (ru) 2000-06-26
NO995591D0 (no) 1999-11-15
SK154399A3 (en) 2000-07-11
EP0981374A2 (en) 2000-03-01
EP0981374B1 (en) 2007-11-21
KR20010012374A (ko) 2001-02-15
CA2289196C (en) 2007-08-07
AU7491898A (en) 1998-12-08
HUP0003393A3 (en) 2001-03-28
YU58599A (sh) 2000-12-28
SK286437B6 (sk) 2008-10-07
JP2001525826A (ja) 2001-12-11
DE69838750T2 (de) 2008-10-30
WO1998051348A2 (en) 1998-11-19
WO1998051348A3 (en) 1999-02-18
PL336887A1 (en) 2000-07-17
BR9809117A (pt) 2000-08-01

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