DE69836429T2 - Impstoffe gegen Hepatitis B die Öl in Wasser Emulsionen enthalten - Google Patents
Impstoffe gegen Hepatitis B die Öl in Wasser Emulsionen enthalten Download PDFInfo
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- DE69836429T2 DE69836429T2 DE69836429T DE69836429T DE69836429T2 DE 69836429 T2 DE69836429 T2 DE 69836429T2 DE 69836429 T DE69836429 T DE 69836429T DE 69836429 T DE69836429 T DE 69836429T DE 69836429 T2 DE69836429 T2 DE 69836429T2
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
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- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
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- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
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- Communicable Diseases (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| GB9718901 | 1997-09-05 | ||
| GBGB9718901.3A GB9718901D0 (en) | 1997-09-05 | 1997-09-05 | Vaccine |
| PCT/EP1998/005714 WO1999012565A1 (en) | 1997-09-05 | 1998-09-02 | Vaccines |
Publications (2)
| Publication Number | Publication Date |
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| DE69836429D1 DE69836429D1 (de) | 2006-12-28 |
| DE69836429T2 true DE69836429T2 (de) | 2007-09-20 |
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| Application Number | Title | Priority Date | Filing Date |
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| DE69836429T Expired - Fee Related DE69836429T2 (de) | 1997-09-05 | 1998-09-02 | Impstoffe gegen Hepatitis B die Öl in Wasser Emulsionen enthalten |
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| Country | Link |
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| US (1) | US6372227B1 (enExample) |
| EP (2) | EP1723966A3 (enExample) |
| JP (1) | JP2001515870A (enExample) |
| AU (1) | AU9623898A (enExample) |
| CA (1) | CA2302637A1 (enExample) |
| DE (1) | DE69836429T2 (enExample) |
| ES (1) | ES2276476T3 (enExample) |
| GB (1) | GB9718901D0 (enExample) |
| WO (1) | WO1999012565A1 (enExample) |
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| FR2646776B1 (fr) * | 1989-05-12 | 1994-06-03 | Pasteur Institut | Utilisation de preparations vaccinantes a base d'adenyl cyclase ou de bacteries les produisant en tant qu'antigenes protecteurs contre les effets des bordetella |
| US6620414B2 (en) * | 1992-03-27 | 2003-09-16 | Smithkline Beecham Biologicals (S.A.) | Hepatitis vaccines containing 3-0-deacylated monophoshoryl lipid A |
| GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| US20010053365A1 (en) * | 1995-04-25 | 2001-12-20 | Smithkline Beecham Biologicals S.A. | Vaccines |
| UA56132C2 (uk) † | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
| DE69838992T2 (de) * | 1997-09-05 | 2008-12-24 | Glaxosmithkline Biologicals S.A., Rixensart | Öl-in-Wasser Emulsionen mit Saponinen |
| US7087236B1 (en) * | 1998-09-01 | 2006-08-08 | Merrion Research I Limited | Method for inducing a cell-mediated immune response and improved parenteral vaccine formulations thereof |
| JP2002537102A (ja) | 1999-02-26 | 2002-11-05 | カイロン コーポレイション | 吸着された高分子および微粒子を有するミクロエマルジョン |
| GB9908885D0 (en) * | 1999-04-19 | 1999-06-16 | Smithkline Beecham Biolog | Vccine |
| US6558670B1 (en) | 1999-04-19 | 2003-05-06 | Smithkline Beechman Biologicals S.A. | Vaccine adjuvants |
| TR200103018T2 (tr) | 1999-04-19 | 2002-02-21 | Beecham Biologicals S.A. Smithkline | İmmünostimülatör oligonükleotid ve saponin içeren katkı bileşikleri. |
| CZ20013916A3 (cs) | 1999-05-13 | 2002-06-12 | American Cyanamid Company | Adjuvantní kombinované prostředky |
| GB9923176D0 (en) * | 1999-09-30 | 1999-12-01 | Smithkline Beecham Biolog | Novel composition |
| WO2001030382A1 (en) | 1999-10-22 | 2001-05-03 | Aventis Pasteur Limited | Method of inducing and/or enhancing an immune response to tumor antigens |
| WO2001037869A1 (en) * | 1999-11-19 | 2001-05-31 | Csl Limited | Vaccine compositions |
| EP1282702B1 (en) | 2000-05-10 | 2006-11-29 | Sanofi Pasteur Limited | Immunogenic polypeptides encoded by mage minigenes and uses thereof |
| SI2266603T1 (sl) | 2000-10-18 | 2012-12-31 | Glaxosmithkline Biologicals S.A. | Tumorska cepiva |
| US20030138434A1 (en) * | 2001-08-13 | 2003-07-24 | Campbell Robert L. | Agents for enhancing the immune response |
| US7361352B2 (en) | 2001-08-15 | 2008-04-22 | Acambis, Inc. | Influenza immunogen and vaccine |
| US7351413B2 (en) | 2002-02-21 | 2008-04-01 | Lorantis, Limited | Stabilized HBc chimer particles as immunogens for chronic hepatitis |
| US6861410B1 (en) * | 2002-03-21 | 2005-03-01 | Chiron Corporation | Immunological adjuvant compositions |
| AU2003254792A1 (en) * | 2002-08-02 | 2004-02-23 | Sumitomo Pharmaceuticals Company, Limited | Bacterial cell wall skeleton component preparaion |
| EP1569515A4 (en) | 2002-10-23 | 2006-04-26 | Glaxosmithkline Biolog Sa | MALARIA vaccine method |
| WO2004060396A2 (en) * | 2002-12-27 | 2004-07-22 | Chiron Corporation | Immunogenic compositions containing phospholpid |
| PL378001A1 (pl) * | 2003-01-29 | 2006-02-20 | Pfizer Products Inc. | Szczepionki przeciw Bordetella bronchiseptica dla psów |
| CA2521051C (en) * | 2003-04-04 | 2012-03-20 | Pfizer Products Inc. | Microfluidized oil-in-water emulsions and vaccine compositions |
| US7972645B2 (en) * | 2003-12-01 | 2011-07-05 | Academia Sinica | Dioscorea extracts for enhancing immune system |
| UA89631C2 (en) * | 2004-04-05 | 2010-02-25 | Пфайзер Продактс Инк. | Vaccine composition |
| US20080032384A1 (en) * | 2004-04-22 | 2008-02-07 | Takehiko Nomura | Pharmaceutical Preparation Containing Bacterial Cell Wall Skeleton |
| GB0417494D0 (en) | 2004-08-05 | 2004-09-08 | Glaxosmithkline Biolog Sa | Vaccine |
| DK1855716T3 (da) * | 2005-02-16 | 2011-03-21 | Cornell Res Foundation Inc | Sammensætninger til udløsning af et immunrespons mod paratuberculosis-underarten af mycobacterium |
| EP1850871A2 (en) * | 2005-02-16 | 2007-11-07 | Novartis Vaccines and Diagnostics, Inc. | Adjuvant composition comprising aluminium phosphate and 3d-mpl |
| GB0503337D0 (en) | 2005-02-17 | 2005-03-23 | Glaxosmithkline Biolog Sa | Compositions |
| GB0504436D0 (en) | 2005-03-03 | 2005-04-06 | Glaxosmithkline Biolog Sa | Vaccine |
| EP1863529A1 (en) * | 2005-03-23 | 2007-12-12 | GlaxoSmithKline Biologicals S.A. | Novel composition |
| EP1910410B1 (en) * | 2005-07-01 | 2011-10-26 | Forsyth Dental Infirmary for Children | Tuberculosis antigen detection assays and vaccines |
| DK1909830T3 (da) * | 2005-08-02 | 2011-12-19 | Novartis Vaccines & Diagnostic | Formindskelse af interferens mellem olieholdige adjuvanser og antigener indeholdende overfladeaktivt middel |
| US11707520B2 (en) | 2005-11-03 | 2023-07-25 | Seqirus UK Limited | Adjuvanted vaccines with non-virion antigens prepared from influenza viruses grown in cell culture |
| HUE051122T2 (hu) | 2005-11-04 | 2021-03-01 | Seqirus Uk Ltd | Sejttenyészetben növesztett influenzavírusból elõállított nemvirion anti-géneket tartalmazó adjuvált vakcinák |
| EA014028B1 (ru) * | 2005-11-04 | 2010-08-30 | Новартис Вэксинс Энд Диагностикс Срл | Эмульсии, содержащие свободное поверхностно-активное вещество в водной фазе в качестве адъюванта сплит вакцин против гриппа |
| GB0522765D0 (en) | 2005-11-08 | 2005-12-14 | Chiron Srl | Combination vaccine manufacture |
| PL3017827T3 (pl) | 2005-12-22 | 2019-04-30 | Glaxosmithkline Biologicals Sa | Szczepionka z koniugatem polisacharydu pneumokokowego |
| GB0607088D0 (en) | 2006-04-07 | 2006-05-17 | Glaxosmithkline Biolog Sa | Vaccine |
| KR101541383B1 (ko) | 2006-03-30 | 2015-08-03 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 면역원성 조성물 |
| US9839685B2 (en) | 2006-04-13 | 2017-12-12 | The Regents Of The University Of Michigan | Methods of inducing human immunodeficiency virus-specific immune responses in a host comprising nasally administering compositions comprising a naonemulsion and recombinant GP120 immunogen |
| US10138279B2 (en) | 2006-04-13 | 2018-11-27 | Regents Of The University Of Michigan | Compositions and methods for Bacillus anthracis vaccination |
| MX2009000660A (es) | 2006-07-17 | 2009-04-08 | Glaxosmithkline Biolog Sa | Vacuna de influenza. |
| US20080014217A1 (en) * | 2006-07-17 | 2008-01-17 | Emmanuel Jules Hanon | Influenza vaccine |
| US20090181078A1 (en) | 2006-09-26 | 2009-07-16 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
| US8273361B2 (en) | 2006-09-26 | 2012-09-25 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
| CN101522218B (zh) * | 2006-10-12 | 2012-09-26 | 葛兰素史密丝克莱恩生物有限公司 | 包含水包油乳液佐剂的疫苗 |
| PL2086582T3 (pl) | 2006-10-12 | 2013-04-30 | Glaxosmithkline Biologicals Sa | Kompozycja zawierająca adiuwant w postaci emulsji typu olej w wodzie |
| HUE031411T2 (en) | 2007-03-02 | 2017-07-28 | Glaxosmithkline Biologicals Sa | New Methods and Preparations |
| WO2008112125A1 (en) * | 2007-03-09 | 2008-09-18 | Merck & Co., Inc. | Papillomavirus vaccine compositions |
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| US9610339B2 (en) | 2007-06-26 | 2017-04-04 | Glaxosmithkline Biologicals, S.A. | Vaccine comprising Streptococcus pneumoniae capsular polysaccharide conjugates |
| ES2539818T3 (es) | 2007-08-02 | 2015-07-06 | Biondvax Pharmaceuticals Ltd. | Vacunas contra la gripe multiepitópicas multiméricas |
| TW200924791A (en) | 2007-08-13 | 2009-06-16 | Glaxosmithkline Biolog Sa | Vaccines |
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| US20100209452A1 (en) * | 2007-10-03 | 2010-08-19 | Immunovaccine Technologies, Inc | Compositions comprising an antigen, an amphipathic compound and a hydrophobic carrier, and uses thereof |
| PL2271360T3 (pl) | 2008-04-16 | 2016-03-31 | Glaxosmithkline Biologicals Sa | Szczepionka |
| EP2293813A4 (en) | 2008-05-23 | 2012-07-11 | Univ Michigan | NANO EMULSION VACCINES |
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Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4806350A (en) * | 1986-04-18 | 1989-02-21 | Norden Laboratories, Inc. | Vaccine formulation |
| NZ230747A (en) | 1988-09-30 | 1992-05-26 | Bror Morein | Immunomodulating matrix comprising a complex of at least one lipid and at least one saponin; certain glycosylated triterpenoid saponins derived from quillaja saponaria molina |
| DE69225710T3 (de) | 1991-07-25 | 2004-10-14 | Idec Pharmaceuticals Corp., San Diego | Anregung von antworten zytotoxischer t-lymphozyten |
| GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| GB9620795D0 (en) * | 1996-10-05 | 1996-11-20 | Smithkline Beecham Plc | Vaccines |
| UA56132C2 (uk) | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
| GB9513261D0 (en) * | 1995-06-29 | 1995-09-06 | Smithkline Beecham Biolog | Vaccines |
-
1997
- 1997-09-05 GB GBGB9718901.3A patent/GB9718901D0/en active Pending
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1998
- 1998-09-02 EP EP06119366A patent/EP1723966A3/en not_active Withdrawn
- 1998-09-02 CA CA002302637A patent/CA2302637A1/en not_active Abandoned
- 1998-09-02 US US09/486,996 patent/US6372227B1/en not_active Expired - Lifetime
- 1998-09-02 EP EP98950005A patent/EP1009430B1/en not_active Expired - Lifetime
- 1998-09-02 DE DE69836429T patent/DE69836429T2/de not_active Expired - Fee Related
- 1998-09-02 JP JP2000510462A patent/JP2001515870A/ja active Pending
- 1998-09-02 AU AU96238/98A patent/AU9623898A/en not_active Abandoned
- 1998-09-02 ES ES98950005T patent/ES2276476T3/es not_active Expired - Lifetime
- 1998-09-02 WO PCT/EP1998/005714 patent/WO1999012565A1/en not_active Ceased
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|---|---|
| WO1999012565A1 (en) | 1999-03-18 |
| JP2001515870A (ja) | 2001-09-25 |
| CA2302637A1 (en) | 1999-03-18 |
| EP1723966A3 (en) | 2007-04-25 |
| AU9623898A (en) | 1999-03-29 |
| EP1009430A1 (en) | 2000-06-21 |
| DE69836429D1 (de) | 2006-12-28 |
| GB9718901D0 (en) | 1997-11-12 |
| EP1009430B1 (en) | 2006-11-15 |
| ES2276476T3 (es) | 2007-06-16 |
| EP1723966A2 (en) | 2006-11-22 |
| US20020058047A1 (en) | 2002-05-16 |
| US6372227B1 (en) | 2002-04-16 |
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