DE69832183D1 - Vorrichtung zum verabreichen von insulin in kontrollierten doserungen durch kontrolle des totalen inhalierten volumens - Google Patents
Vorrichtung zum verabreichen von insulin in kontrollierten doserungen durch kontrolle des totalen inhalierten volumensInfo
- Publication number
- DE69832183D1 DE69832183D1 DE69832183T DE69832183T DE69832183D1 DE 69832183 D1 DE69832183 D1 DE 69832183D1 DE 69832183 T DE69832183 T DE 69832183T DE 69832183 T DE69832183 T DE 69832183T DE 69832183 D1 DE69832183 D1 DE 69832183D1
- Authority
- DE
- Germany
- Prior art keywords
- checking
- administering insulin
- controlled doses
- inhaled volume
- total inhaled
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/001—Particle size control
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0031—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up by bursting or breaking the package, i.e. without cutting or piercing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0043—Non-destructive separation of the package, e.g. peeling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
- A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
- A61M15/0051—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a tape, e.g. strips
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0066—Inhalators with dosage or measuring devices with means for varying the dose size
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/008—Electronic counters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/14—Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
- A61M16/142—Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase with semi-permeable walls separating the liquid from the respiratory gas
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
- B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
- B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
- B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
- A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
- A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
- A61J7/0418—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with electronic history memory
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
- A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
- A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
- A61J7/0427—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with direct interaction with a dispensing or delivery system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
- A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
- A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
- A61J7/0427—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with direct interaction with a dispensing or delivery system
- A61J7/0445—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with direct interaction with a dispensing or delivery system for preventing drug dispensing during a predetermined time period
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0085—Inhalators using ultrasonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
- A61M2016/0018—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
- A61M2016/0021—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with a proportional output signal, e.g. from a thermistor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M2016/003—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
- A61M2016/0033—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical
- A61M2016/0036—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical in the breathing tube and used in both inspiratory and expiratory phase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/062—Desiccants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/50—General characteristics of the apparatus with microprocessors or computers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/82—Internal energy supply devices
- A61M2205/8206—Internal energy supply devices battery-operated
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/846,243 US5884620A (en) | 1993-01-29 | 1997-04-25 | Inhaled insulin dosage control delivery enhanced by controlling total inhaled volume |
US846243 | 1997-04-25 | ||
PCT/US1998/008238 WO1998048873A1 (en) | 1997-04-25 | 1998-04-23 | Device for administering insulin in controlled dosages by controlling total inhaled volume |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69832183D1 true DE69832183D1 (de) | 2005-12-08 |
DE69832183T2 DE69832183T2 (de) | 2006-08-03 |
Family
ID=25297344
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69832183T Expired - Lifetime DE69832183T2 (de) | 1997-04-25 | 1998-04-23 | Vorrichtung zum verabreichen von insulin in kontrollierten doserungen durch kontrolle des totalen inhalierten volumens |
DE69840638T Expired - Lifetime DE69840638D1 (de) | 1997-04-25 | 1998-04-23 | Vorrichtung zum Verabreichen von Insulin in kontrollierten Doserungen durch Kontrolle des totalen Inhalierten Volumens |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69840638T Expired - Lifetime DE69840638D1 (de) | 1997-04-25 | 1998-04-23 | Vorrichtung zum Verabreichen von Insulin in kontrollierten Doserungen durch Kontrolle des totalen Inhalierten Volumens |
Country Status (9)
Country | Link |
---|---|
US (8) | US5888477A (de) |
EP (2) | EP1011767B1 (de) |
JP (1) | JP2002504833A (de) |
AR (1) | AR007491A1 (de) |
AT (1) | ATE308356T1 (de) |
AU (1) | AU741913B2 (de) |
DE (2) | DE69832183T2 (de) |
ES (1) | ES2321951T3 (de) |
WO (1) | WO1998048873A1 (de) |
Families Citing this family (224)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6024090A (en) * | 1993-01-29 | 2000-02-15 | Aradigm Corporation | Method of treating a diabetic patient by aerosolized administration of insulin lispro |
US5888477A (en) * | 1993-01-29 | 1999-03-30 | Aradigm Corporation | Use of monomeric insulin as a means for improving the bioavailability of inhaled insulin |
US7448375B2 (en) * | 1993-01-29 | 2008-11-11 | Aradigm Corporation | Method of treating diabetes mellitus in a patient |
US6632456B1 (en) * | 1993-06-24 | 2003-10-14 | Astrazeneca Ab | Compositions for inhalation |
US6428771B1 (en) * | 1995-05-15 | 2002-08-06 | Pharmaceutical Discovery Corporation | Method for drug delivery to the pulmonary system |
SE9700423D0 (sv) * | 1997-02-07 | 1997-02-07 | Astra Ab | Disposable inhaler |
US6349719B2 (en) | 1997-02-24 | 2002-02-26 | Aradigm Corporation | Formulation and devices for monitoring the efficacy of the delivery of aerosols |
US6192882B1 (en) * | 1997-02-24 | 2001-02-27 | Aradigm Corporation | Formulation and devices for monitoring the efficacy of the delivery of aerosols |
DE19733651A1 (de) * | 1997-08-04 | 1999-02-18 | Boehringer Ingelheim Pharma | Wässrige Aerosolzubereitungen enthaltend biologisch aktive Markomoleküle und Verfahren zur Erzeugung entsprechender Aerosole |
US20060239930A1 (en) * | 1997-08-04 | 2006-10-26 | Herbert Lamche | Process for nebulizing aqueous compositions containing highly concentrated insulin |
ZA989744B (en) * | 1997-10-31 | 2000-04-26 | Lilly Co Eli | Method for administering acylated insulin. |
WO1999047196A1 (en) * | 1998-03-16 | 1999-09-23 | Inhale Therapeutic Systems, Inc. | Aerosolized active agent delivery |
EP1083951A4 (de) * | 1998-06-12 | 2004-07-07 | Aradigm Corp | Methode zur austragung von polynukleotide in form eines aerosols in den respirationstrakt |
US6956021B1 (en) * | 1998-08-25 | 2005-10-18 | Advanced Inhalation Research, Inc. | Stable spray-dried protein formulations |
UA73924C2 (en) * | 1998-10-09 | 2005-10-17 | Nektar Therapeutics | Device for delivering active agent formulation to lungs of human patient |
US6234167B1 (en) | 1998-10-14 | 2001-05-22 | Chrysalis Technologies, Incorporated | Aerosol generator and methods of making and using an aerosol generator |
US20060171899A1 (en) * | 1998-12-10 | 2006-08-03 | Akwete Adjei | Water-stabilized aerosol formulation system and method of making |
US20040214747A1 (en) * | 1999-01-06 | 2004-10-28 | Dimarchi Richard Dennis | Method for administering monomeric insulin |
ATE545652T1 (de) | 1999-06-29 | 2012-03-15 | Mannkind Corp | Reinigung und stabilisierung von proteinen und peptiden in pharmaceutischen agentien |
US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
US6606992B1 (en) * | 1999-06-30 | 2003-08-19 | Nektar Therapeutics | Systems and methods for aerosolizing pharmaceutical formulations |
US7464706B2 (en) * | 1999-07-23 | 2008-12-16 | Mannkind Corporation | Unit dose cartridge and dry powder inhaler |
US7305986B1 (en) | 1999-07-23 | 2007-12-11 | Mannkind Corporation | Unit dose capsules for use in a dry powder inhaler |
US7678364B2 (en) | 1999-08-25 | 2010-03-16 | Alkermes, Inc. | Particles for inhalation having sustained release properties |
WO2001051030A1 (en) * | 2000-01-10 | 2001-07-19 | Dura Pharmaceuticals, Inc. | Pharmaceutical formulation and method for pulmonary and oral delivery |
GB0003839D0 (en) * | 2000-02-19 | 2000-04-05 | Glaxo Group Ltd | Housing for an inhaler |
MY136453A (en) * | 2000-04-27 | 2008-10-31 | Philip Morris Usa Inc | "improved method and apparatus for generating an aerosol" |
US6629524B1 (en) | 2000-07-12 | 2003-10-07 | Ponwell Enterprises Limited | Inhaler |
DE10040528A1 (de) * | 2000-08-18 | 2002-02-28 | Pari Gmbh | Inhalationsvorrichtung und Verfahren zur Erzeugung eines Partikelnebels für Inhalationszwecke |
GB0025749D0 (en) * | 2000-10-20 | 2000-12-06 | Glaxo Group Ltd | Inhaler |
US6539939B2 (en) * | 2000-12-18 | 2003-04-01 | Darren Rubin | Multi-function oral breathing support system |
US6681998B2 (en) | 2000-12-22 | 2004-01-27 | Chrysalis Technologies Incorporated | Aerosol generator having inductive heater and method of use thereof |
US6701921B2 (en) * | 2000-12-22 | 2004-03-09 | Chrysalis Technologies Incorporated | Aerosol generator having heater in multilayered composite and method of use thereof |
US6491233B2 (en) | 2000-12-22 | 2002-12-10 | Chrysalis Technologies Incorporated | Vapor driven aerosol generator and method of use thereof |
US7077130B2 (en) * | 2000-12-22 | 2006-07-18 | Chrysalis Technologies Incorporated | Disposable inhaler system |
US6501052B2 (en) | 2000-12-22 | 2002-12-31 | Chrysalis Technologies Incorporated | Aerosol generator having multiple heating zones and methods of use thereof |
US6799572B2 (en) | 2000-12-22 | 2004-10-05 | Chrysalis Technologies Incorporated | Disposable aerosol generator system and methods for administering the aerosol |
GB0100756D0 (en) | 2001-01-11 | 2001-02-21 | Powderject Res Ltd | Needleless syringe |
US7073499B1 (en) | 2001-02-06 | 2006-07-11 | Injet Digital Aerosols Limited | Inhaler with airflow regulation |
US6652838B2 (en) * | 2001-04-05 | 2003-11-25 | Robert E. Weinstein | Method for treating diabetes mellitus |
CA2438290C (en) | 2001-04-25 | 2007-03-27 | Matsushita Electric Industrial Co., Ltd. | Projection-type display apparatus |
DE10123749A1 (de) * | 2001-05-16 | 2002-12-12 | Inamed Gmbh | Vorrichtung zum Verabreichen von Aerosolen |
US7458374B2 (en) | 2002-05-13 | 2008-12-02 | Alexza Pharmaceuticals, Inc. | Method and apparatus for vaporizing a compound |
US7645442B2 (en) | 2001-05-24 | 2010-01-12 | Alexza Pharmaceuticals, Inc. | Rapid-heating drug delivery article and method of use |
US20030051728A1 (en) | 2001-06-05 | 2003-03-20 | Lloyd Peter M. | Method and device for delivering a physiologically active compound |
US7090830B2 (en) * | 2001-05-24 | 2006-08-15 | Alexza Pharmaceuticals, Inc. | Drug condensation aerosols and kits |
US20070122353A1 (en) * | 2001-05-24 | 2007-05-31 | Hale Ron L | Drug condensation aerosols and kits |
US7244703B2 (en) * | 2001-06-22 | 2007-07-17 | Bentley Pharmaceuticals, Inc. | Pharmaceutical compositions and methods for peptide treatment |
DE10131516B4 (de) * | 2001-07-02 | 2004-05-06 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Steuereinheit zur Flussregulierung |
US6568390B2 (en) | 2001-09-21 | 2003-05-27 | Chrysalis Technologies Incorporated | Dual capillary fluid vaporizing device |
US6640050B2 (en) | 2001-09-21 | 2003-10-28 | Chrysalis Technologies Incorporated | Fluid vaporizing device having controlled temperature profile heater/capillary tube |
US20030068361A1 (en) * | 2001-10-09 | 2003-04-10 | Rimona Margalit | Liposome-encapsulated insulin formulations |
US6681769B2 (en) | 2001-12-06 | 2004-01-27 | Crysalis Technologies Incorporated | Aerosol generator having a multiple path heater arrangement and method of use thereof |
US6804458B2 (en) | 2001-12-06 | 2004-10-12 | Chrysalis Technologies Incorporated | Aerosol generator having heater arranged to vaporize fluid in fluid passage between bonded layers of laminate |
US20030168057A1 (en) * | 2001-12-14 | 2003-09-11 | Inhale Therapeutic Systems, Inc. | Electronically controllable aerosol delivery |
US6701922B2 (en) | 2001-12-20 | 2004-03-09 | Chrysalis Technologies Incorporated | Mouthpiece entrainment airflow control for aerosol generators |
US6705316B2 (en) | 2002-03-11 | 2004-03-16 | Battelle Pulmonary Therapeutics, Inc. | Pulmonary dosing system and method |
US7008644B2 (en) * | 2002-03-20 | 2006-03-07 | Advanced Inhalation Research, Inc. | Method and apparatus for producing dry particles |
CA2478801A1 (en) * | 2002-03-20 | 2003-10-02 | Advanced Inhalation Research, Inc. | Method for administration of growth hormone via pulmonary delivery |
AU2003220125B2 (en) | 2002-03-20 | 2006-06-15 | Mannkind Corporation | Inhalation apparatus |
US20050163725A1 (en) * | 2002-03-20 | 2005-07-28 | Blizzard Charles D. | Method for administration of growth hormone via pulmonary delivery |
US6830046B2 (en) | 2002-04-29 | 2004-12-14 | Hewlett-Packard Development Company, L.P. | Metered dose inhaler |
US20040151059A1 (en) * | 2002-05-01 | 2004-08-05 | Roberts Ii William Leroy | Deagglomerator apparatus and method |
US6985798B2 (en) | 2002-05-10 | 2006-01-10 | Oriel Therapeutics, Inc. | Dry powder dose filling systems and related methods |
US6889690B2 (en) * | 2002-05-10 | 2005-05-10 | Oriel Therapeutics, Inc. | Dry powder inhalers, related blister devices, and associated methods of dispensing dry powder substances and fabricating blister packages |
US7677411B2 (en) * | 2002-05-10 | 2010-03-16 | Oriel Therapeutics, Inc. | Apparatus, systems and related methods for processing, dispensing and/or evaluatingl dry powders |
US7118010B2 (en) | 2002-05-10 | 2006-10-10 | Oriel Therapeutics, Inc. | Apparatus, systems and related methods for dispensing and /or evaluating dry powders |
US20060193788A1 (en) * | 2002-11-26 | 2006-08-31 | Hale Ron L | Acute treatment of headache with phenothiazine antipsychotics |
US7185651B2 (en) * | 2002-06-18 | 2007-03-06 | Nektar Therapeutics | Flow regulator for aerosol drug delivery and methods |
JP2006507110A (ja) * | 2002-06-27 | 2006-03-02 | オリエル・セラピューティクス,インコーポレイテッド | 非医薬品の乾燥粉末を処理、分配及び/又は評価するための装置、システム及び関連した方法 |
GB0215270D0 (en) | 2002-07-02 | 2002-08-14 | Optinose As | Nasal devices |
EP1567164B1 (de) * | 2002-11-26 | 2009-01-14 | Alexza Pharmaceuticals, Inc. | Verwendung von loxapine für die herstellung eines mittels zur behandlung von schmerz |
CA2507158A1 (en) * | 2002-11-26 | 2004-06-10 | Alexza Molecular Delivery Corporation | Treatment of headache with antipsychotics delivered by inhalation |
US20040105818A1 (en) * | 2002-11-26 | 2004-06-03 | Alexza Molecular Delivery Corporation | Diuretic aerosols and methods of making and using them |
US7913688B2 (en) | 2002-11-27 | 2011-03-29 | Alexza Pharmaceuticals, Inc. | Inhalation device for producing a drug aerosol |
US20050236296A1 (en) * | 2002-12-30 | 2005-10-27 | Nektar Therapeutics (Formerly Inhale Therapeutic Systems, Inc.) | Carry case for aerosolization apparatus |
US7683029B2 (en) * | 2003-05-07 | 2010-03-23 | Philip Morris Usa Inc. | Liquid aerosol formulations containing insulin and aerosol generating devices and methods for generating aerosolized insulin |
CA2526470A1 (en) | 2003-05-21 | 2004-12-02 | Alexza Pharmaceuticals, Inc. | Percussively ignited or electrically ignited self-contained heating unit and drug-supply unit employing same |
US7591801B2 (en) | 2004-02-26 | 2009-09-22 | Dexcom, Inc. | Integrated delivery device for continuous glucose sensor |
US7305984B2 (en) * | 2003-09-25 | 2007-12-11 | Deka Products Limited Partnership | Metering system and method for aerosol delivery |
US7342660B2 (en) * | 2003-09-25 | 2008-03-11 | Deka Products Limited Partnership | Detection system and method for aerosol delivery |
US7338171B2 (en) * | 2003-10-27 | 2008-03-04 | Jen-Chuen Hsieh | Method and apparatus for visual drive control |
US7377277B2 (en) * | 2003-10-27 | 2008-05-27 | Oriel Therapeutics, Inc. | Blister packages with frames and associated methods of fabricating dry powder drug containment systems |
US7451761B2 (en) * | 2003-10-27 | 2008-11-18 | Oriel Therapeutics, Inc. | Dry powder inhalers, related blister package indexing and opening mechanisms, and associated methods of dispensing dry powder substances |
SE0303570L (sv) * | 2003-12-03 | 2005-06-04 | Microdrug Ag | Fukt-känslig medicinsk produkt |
KR100978717B1 (ko) * | 2003-12-08 | 2010-08-30 | 씨펙스 파마슈티칼스, 인코포레이티드 | 인슐린 치료를 위한 약제 조성물 및 방법 |
EP1708738B1 (de) * | 2004-01-12 | 2016-05-04 | MannKind Corporation | Verfahren zur verringerung des proinsulinspiegels im serum bei zuckerkranken mit type 2 diabetes |
WO2005072803A1 (en) * | 2004-01-16 | 2005-08-11 | Biodel, Inc. | Sublingual drug delivery device |
US7819115B2 (en) * | 2004-01-30 | 2010-10-26 | Hewlett-Packard Development Company, L.P. | Inhalers and methods of controlling airflow in inhalers |
US7380550B2 (en) * | 2004-01-30 | 2008-06-03 | Hewlett-Packard Development Company, L.P. | Systems and methods for particle detection |
WO2009048462A1 (en) | 2007-10-09 | 2009-04-16 | Dexcom, Inc. | Integrated insulin delivery system with continuous glucose sensor |
EP1721421A1 (de) * | 2004-02-26 | 2006-11-15 | Novo Nordisk A/S | Verfahren und system zur sicheren paarung drahtloser kommunikationseinrichtungen |
JP5022213B2 (ja) * | 2004-03-12 | 2012-09-12 | バイオデル, インコーポレイテッド | 迅速に作用する薬物送達組成物 |
US20080090753A1 (en) * | 2004-03-12 | 2008-04-17 | Biodel, Inc. | Rapid Acting Injectable Insulin Compositions |
WO2005091540A1 (en) * | 2004-03-19 | 2005-09-29 | Novo Nordisk A/S | A reduced size transmission data packet header format for a medical device |
WO2005093629A2 (en) * | 2004-03-26 | 2005-10-06 | Novo Nordisk A/S | Device for displaying data relevant for a diabetic patient |
BRPI0509991A (pt) * | 2004-04-20 | 2007-10-16 | Aerogen Inc | aparelho de fornecimento em aerossol, métodos e composições para sistemas de respiração auxiliados por pressão |
US7946291B2 (en) | 2004-04-20 | 2011-05-24 | Novartis Ag | Ventilation systems and methods employing aerosol generators |
AU2005238962B2 (en) * | 2004-04-23 | 2011-05-26 | Philip Morris Products S.A. | Aerosol generators and methods for producing aerosols |
US7540286B2 (en) | 2004-06-03 | 2009-06-02 | Alexza Pharmaceuticals, Inc. | Multiple dose condensation aerosol devices and methods of forming condensation aerosols |
WO2005123165A1 (en) * | 2004-06-15 | 2005-12-29 | Novo Nordisk A/S | Inhalation breath assistant apparatus and method for assisting in inhalation therapies |
FR2872798B1 (fr) * | 2004-07-09 | 2007-10-05 | Valois Sas | Ensemble de blisters pour dispositif d'inhalation |
BRPI0514263B8 (pt) | 2004-08-20 | 2021-05-25 | Mannkind Corp | método para a síntese de bis-3,6-[4-aminobutil]-2,5-dicetopiperazina n-protegida |
HUE026134T2 (en) | 2004-08-23 | 2016-05-30 | Mannkind Corp | Microparticles containing diketopiperazine salts for drug delivery |
WO2006021566A2 (en) * | 2004-08-24 | 2006-03-02 | Novo Nordisk A/S | Giving a service to a patient |
WO2006048417A1 (en) | 2004-11-02 | 2006-05-11 | Novo Nordisk A/S | Inhalation therapy compliance tracking system and apparatus |
JP2008526893A (ja) * | 2005-01-10 | 2008-07-24 | マンカインド コーポレイション | 肺における吸入可能なインスリンの自然増加を最少化するための方法及び組成物 |
GB0507100D0 (en) * | 2005-04-08 | 2005-05-11 | Team Holdings Uk Ltd | Improvements in or relating to inhalers |
UA94711C2 (uk) * | 2005-05-25 | 2011-06-10 | Аэроджен, Инк. | Вібраційна система (варіанти) та спосіб її виготовлення (варіанти), спосіб вібрування пластини (варіанти), система виробництва аерозолю та спосіб лікування пацієнта |
WO2007008825A2 (en) * | 2005-07-11 | 2007-01-18 | Emory University | System and method for optimized delivery of an aerosol to the respiratory tract |
US7900625B2 (en) * | 2005-08-26 | 2011-03-08 | North Carolina State University | Inhaler system for targeted maximum drug-aerosol delivery |
JP4789555B2 (ja) * | 2005-09-13 | 2011-10-12 | キヤノン株式会社 | 液剤吐出装置 |
ES2640282T3 (es) * | 2005-09-14 | 2017-11-02 | Mannkind Corporation | Método de formulación de fármacos basado en el aumento de la afinidad de superficies de micropartículas cristalinas para agentes activos |
US7713929B2 (en) | 2006-04-12 | 2010-05-11 | Biodel Inc. | Rapid acting and long acting insulin combination formulations |
US8084420B2 (en) * | 2005-09-29 | 2011-12-27 | Biodel Inc. | Rapid acting and long acting insulin combination formulations |
US20070086952A1 (en) * | 2005-09-29 | 2007-04-19 | Biodel, Inc. | Rapid Acting and Prolonged Acting Inhalable Insulin Preparations |
US9656903B2 (en) * | 2005-11-04 | 2017-05-23 | Ocv Intellectual Capital, Llc | Method of manufacturing high strength glass fibers in a direct melt operation and products formed there from |
EP1993633B1 (de) | 2006-02-09 | 2016-11-09 | Deka Products Limited Partnership | Pumpsysteme und verfahren zur flüssigkeitsabgabe mit krafteinwirkungsanordnung |
CN104383546B (zh) | 2006-02-22 | 2021-03-02 | 曼金德公司 | 用于改善包含二酮哌嗪和活性剂的微粒的药物性质的方法 |
WO2007106686A2 (en) * | 2006-03-10 | 2007-09-20 | Novo Nordisk A/S | Medical apparatus and method for homogenous aerosol creation |
WO2007116953A1 (en) * | 2006-04-10 | 2007-10-18 | Canon Kabushiki Kaisha | Ingesta administration device |
JP2009533471A (ja) * | 2006-04-12 | 2009-09-17 | バイオデル, インコーポレイテッド | 即効型および長時間作用型組合せインスリン製剤 |
WO2007121318A2 (en) * | 2006-04-12 | 2007-10-25 | Emisphere Technologies, Inc. | Formulations for delivering insulin |
JP4895388B2 (ja) | 2006-07-25 | 2012-03-14 | キヤノン株式会社 | 薬剤吐出装置 |
AU2007281433A1 (en) | 2006-08-04 | 2008-02-07 | Nastech Pharmaceutical Company Inc. | Compositions for intranasal delivery of human insulin and uses thereof |
ES2594867T3 (es) | 2007-03-09 | 2016-12-23 | Alexza Pharmaceuticals, Inc. | Unidad de calentamiento para usar en un dispositivo de administración de fármaco |
US8616199B2 (en) * | 2007-03-16 | 2013-12-31 | Canon Kabushiki Kaisha | Inhaler and ejection head unit attachable to the inhaler |
WO2008118387A2 (en) * | 2007-03-23 | 2008-10-02 | Wayne State University | Erythrocyte atp-release modulators |
WO2008124522A2 (en) * | 2007-04-04 | 2008-10-16 | Biodel, Inc. | Amylin formulations |
GB0708758D0 (en) * | 2007-05-04 | 2007-06-13 | Powderject Res Ltd | Particle cassettes and process thereof |
US8297280B2 (en) * | 2007-07-20 | 2012-10-30 | Canon Kabushiki Kaisha | Inhaler |
US8261738B2 (en) * | 2007-07-24 | 2012-09-11 | Respironics Respiratory Drug Delivery (Uk) Ltd. | Apparatus and method for maintaining consistency for aerosol drug delivery treatments |
US20090042065A1 (en) * | 2007-08-10 | 2009-02-12 | Mphase Technologies, Inc. | Event Activated Micro Control Devices |
US7814902B2 (en) * | 2007-09-18 | 2010-10-19 | Robert Abrams | Semi-automatic emergency medication dose nebulizer |
US8291902B2 (en) | 2007-09-18 | 2012-10-23 | Robert Abrams | Enhanced semi-automatic emergency medication dose nebulizer |
US8015969B2 (en) * | 2007-09-18 | 2011-09-13 | Robert Abrams | Semi-automatic emergency medication dose nebulizer |
US7836885B2 (en) * | 2007-09-18 | 2010-11-23 | Robert Abrams | Semi-automatic emergency medication dose nebulizer |
US20090071470A1 (en) * | 2007-09-18 | 2009-03-19 | Robert Abrams | Emergency medication dose nebulizer |
US20090151716A1 (en) * | 2007-09-18 | 2009-06-18 | Robert Abrams | Semi-automatic emergency medication dose nebulizer |
US8785396B2 (en) | 2007-10-24 | 2014-07-22 | Mannkind Corporation | Method and composition for treating migraines |
CA2707483A1 (en) | 2007-11-30 | 2009-06-11 | Wolfgang Fraunhofer | Protein formulations and methods of making same |
EP2534957B1 (de) | 2007-12-14 | 2015-05-27 | AeroDesigns, Inc | Abgabe von Aerosol-sprühbaren Produkten |
EP2077132A1 (de) | 2008-01-02 | 2009-07-08 | Boehringer Ingelheim Pharma GmbH & Co. KG | Abgabevorrichtung, Aufbewahrungsvorrichtung und Verfahren zur Abgabe einer Formulierung |
WO2009089181A1 (en) * | 2008-01-04 | 2009-07-16 | Blodel, Inc. | Insulin formulations for insulin release as a function of tissue glucose levels |
JP5667041B2 (ja) * | 2008-03-27 | 2015-02-12 | マンカインド コーポレイション | 乾燥粉末吸入システム |
JP2009268665A (ja) * | 2008-05-07 | 2009-11-19 | Canon Inc | 吸入装置 |
US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
IL279542B2 (en) | 2008-06-13 | 2023-10-01 | Mannkind Corp | Dry powder inhaler and drug delivery system |
CA2728523C (en) | 2008-06-20 | 2020-03-10 | Mannkind Corporation | An interactive apparatus and method for real-time profiling of inhalation efforts |
WO2010011329A2 (en) * | 2008-07-23 | 2010-01-28 | Map Pharmaceuticals, Inc. | The delivery of powdered drug via inhalation |
TWI614024B (zh) | 2008-08-11 | 2018-02-11 | 曼凱公司 | 超快起作用胰島素之用途 |
US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
US9060927B2 (en) * | 2009-03-03 | 2015-06-23 | Biodel Inc. | Insulin formulations for rapid uptake |
EP2405963B1 (de) | 2009-03-11 | 2013-11-06 | MannKind Corporation | Gerät, system und verfahren zur messung von widerstand in einem inhaliergerät |
US20100242955A1 (en) * | 2009-03-19 | 2010-09-30 | Hansen Leland G | Aerosolized Drug Delivery System |
JP5670421B2 (ja) | 2009-03-31 | 2015-02-18 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | コンポーネント表面のコーティング方法 |
EP2432531B1 (de) | 2009-05-18 | 2019-03-06 | Boehringer Ingelheim International GmbH | Adapter, inhalationseinrichtung und zerstäuber |
TWI513692B (zh) * | 2009-06-12 | 2015-12-21 | Mannkind Corp | 具限定異構物含量之二酮基哌微粒子 |
MY157166A (en) | 2009-06-12 | 2016-05-13 | Mankind Corp | Diketopiperazine microparticles with defined specific surface areas |
US9149605B2 (en) | 2009-07-28 | 2015-10-06 | Clement Kleinstreuer | Methods and devices for targeted injection of microspheres |
US9016147B2 (en) | 2009-11-03 | 2015-04-28 | Mannkind Corporation | Apparatus and method for simulating inhalation efforts |
US10016568B2 (en) | 2009-11-25 | 2018-07-10 | Boehringer Ingelheim International Gmbh | Nebulizer |
JP5658268B2 (ja) | 2009-11-25 | 2015-01-21 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ネブライザ |
MX2012005961A (es) | 2009-11-25 | 2012-06-14 | Boehringer Ingelheim Int | Nebulizador. |
US20130269684A1 (en) | 2012-04-16 | 2013-10-17 | Dance Pharmaceuticals, Inc. | Methods and systems for supplying aerosolization devices with liquid medicaments |
US9545488B2 (en) | 2010-01-12 | 2017-01-17 | Dance Biopharm Inc. | Preservative-free single dose inhaler systems |
US8950394B2 (en) | 2010-01-12 | 2015-02-10 | Dance Biopharm Inc. | Preservative-free single dose inhaler systems |
US9743691B2 (en) | 2010-05-15 | 2017-08-29 | Rai Strategic Holdings, Inc. | Vaporizer configuration, control, and reporting |
US10159278B2 (en) | 2010-05-15 | 2018-12-25 | Rai Strategic Holdings, Inc. | Assembly directed airflow |
US9095175B2 (en) * | 2010-05-15 | 2015-08-04 | R. J. Reynolds Tobacco Company | Data logging personal vaporizing inhaler |
US10136672B2 (en) | 2010-05-15 | 2018-11-27 | Rai Strategic Holdings, Inc. | Solderless directly written heating elements |
US9861772B2 (en) | 2010-05-15 | 2018-01-09 | Rai Strategic Holdings, Inc. | Personal vaporizing inhaler cartridge |
US9999250B2 (en) | 2010-05-15 | 2018-06-19 | Rai Strategic Holdings, Inc. | Vaporizer related systems, methods, and apparatus |
US8757147B2 (en) | 2010-05-15 | 2014-06-24 | Minusa Holdings Llc | Personal vaporizing inhaler with internal light source |
US9259035B2 (en) | 2010-05-15 | 2016-02-16 | R. J. Reynolds Tobacco Company | Solderless personal vaporizing inhaler |
BR112012033060A2 (pt) | 2010-06-21 | 2018-02-27 | Mannkind Corp | métodos de sistema de liberação de fármaco em pó seco |
WO2011160932A1 (en) | 2010-06-24 | 2011-12-29 | Boehringer Ingelheim International Gmbh | Nebulizer |
EP2694220B1 (de) | 2011-04-01 | 2020-05-06 | Boehringer Ingelheim International GmbH | Medizinisches gerät mit behälter |
CN105667994B (zh) | 2011-04-01 | 2018-04-06 | 曼金德公司 | 用于药物药盒的泡罩包装 |
EP2696711A4 (de) | 2011-04-12 | 2015-03-25 | Sis Resources Ltd | Batteriestecker für elektronische zigaretten mit seitlichem lufteinlass |
US9827384B2 (en) | 2011-05-23 | 2017-11-28 | Boehringer Ingelheim International Gmbh | Nebulizer |
WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
EP2748670B1 (de) | 2011-08-24 | 2015-11-18 | Rockwell Collins, Inc. | Tragbare datenanzeige |
CN103945859A (zh) | 2011-10-24 | 2014-07-23 | 曼金德公司 | 用于治疗疼痛的方法和组合物 |
WO2013114371A1 (en) | 2012-02-01 | 2013-08-08 | Protalix Ltd. | Dry powder formulations of dnase i |
WO2013152894A1 (de) | 2012-04-13 | 2013-10-17 | Boehringer Ingelheim International Gmbh | Zerstäuber mit kodiermitteln |
MX354163B (es) | 2012-07-12 | 2018-02-15 | Mannkind Corp | Sistemas y métodos de suministro de fármaco en polvo seco. |
WO2014066856A1 (en) | 2012-10-26 | 2014-05-01 | Mannkind Corporation | Inhalable influenza vaccine compositions and methods |
US10034988B2 (en) | 2012-11-28 | 2018-07-31 | Fontem Holdings I B.V. | Methods and devices for compound delivery |
BR112015023168B1 (pt) | 2013-03-15 | 2021-08-10 | Mannkind Corporation | Composição de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina cristalina, método de produção de partículas de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina e uso de uma composição de dicetopiperazina cristalina |
US9884157B2 (en) | 2013-03-15 | 2018-02-06 | Microdose Therapeutx, Inc. | Inhalation device, control method and computer program |
EP2981317A2 (de) * | 2013-04-04 | 2016-02-10 | The USA As Represented by the Secretary Department of Health and Human Services Centers for Disease Control And Prevention | Nasales aerosolfreisetzungssystem |
EP3838316B1 (de) * | 2013-07-11 | 2024-04-03 | Alexza Pharmaceuticals, Inc. | System zur medikamentenabgabe und medikamentenentwöhnung |
KR102321339B1 (ko) | 2013-07-18 | 2021-11-02 | 맨카인드 코포레이션 | 열-안정성 건조 분말 약제학적 조성물 및 방법 |
JP2016530930A (ja) | 2013-08-05 | 2016-10-06 | マンカインド コーポレイション | 通気装置及び方法 |
EP2835146B1 (de) | 2013-08-09 | 2020-09-30 | Boehringer Ingelheim International GmbH | Zerstäuber |
EP3030298B1 (de) | 2013-08-09 | 2017-10-11 | Boehringer Ingelheim International GmbH | Vernebler |
WO2015042412A1 (en) | 2013-09-20 | 2015-03-26 | E-Nicotine Technology. Inc. | Devices and methods for modifying delivery devices |
WO2015148905A1 (en) | 2014-03-28 | 2015-10-01 | Mannkind Corporation | Use of ultrarapid acting insulin |
SI3928818T1 (sl) | 2014-05-07 | 2023-04-28 | Boehringer Ingelheim International Gmbh | Razpršilnik in vsebnik |
DK3139979T3 (da) | 2014-05-07 | 2023-10-09 | Boehringer Ingelheim Int | Enhed, forstøver og fremgangsmåde |
ES2874029T3 (es) | 2014-05-07 | 2021-11-04 | Boehringer Ingelheim Int | Nebulizador |
US10307550B2 (en) | 2014-06-09 | 2019-06-04 | Dance Biopharm Inc. | Liquid drug cartridges and associated dispenser |
US11273271B2 (en) | 2014-07-01 | 2022-03-15 | Aerami Therapeutics, Inc. | Aerosolization system with flow restrictor and feedback device |
US10471222B2 (en) | 2014-07-01 | 2019-11-12 | Dance Biopharm Inc. | Aerosolization system with flow restrictor and feedback device |
US10857313B2 (en) | 2014-07-01 | 2020-12-08 | Aerami Therapeutics, Inc. | Liquid nebulization systems and methods |
WO2016030777A1 (en) | 2014-08-26 | 2016-03-03 | Asmedic Ltd. | Drug delivery apparatus |
US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
NZ733912A (en) | 2015-01-04 | 2023-04-28 | Protalix Ltd | Modified dnase and uses thereof |
WO2017112748A1 (en) | 2015-12-21 | 2017-06-29 | 3M Innovative Properties Company | Flow govenors for use in medicinal inhalers |
US11376379B2 (en) | 2015-12-21 | 2022-07-05 | Kindeva Drug Delivery L.P. | Flow governor assemblies for use in medicinal inhalers |
JP6774508B2 (ja) | 2016-05-03 | 2020-10-28 | ニューマ・リスパイラトリー・インコーポレイテッド | 流体を肺系に供給するための液滴送達装置、及びその使用方法 |
BR112018073742B1 (pt) | 2016-05-19 | 2023-12-26 | Mannkind Corporation | Aparelho acessório de inalador, sistema de monitoramento e detecção, e método de monitoramento e detecção |
US11019847B2 (en) * | 2016-07-28 | 2021-06-01 | Rai Strategic Holdings, Inc. | Aerosol delivery devices including a selector and related methods |
CA3064005C (en) | 2017-05-19 | 2023-03-07 | Pneuma Respiratory, Inc. | Dry powder delivery device and methods of use |
CN110662573A (zh) * | 2017-05-26 | 2020-01-07 | 微剂量治疗公司 | 带有合成喷射的吸入器 |
CN111526914A (zh) | 2017-10-04 | 2020-08-11 | 精呼吸股份有限公司 | 电子呼吸致动式直线型液滴输送装置及其使用方法 |
EP4344719A2 (de) | 2017-10-17 | 2024-04-03 | Pneuma Respiratory, Inc. | Nasale arzneimittelabgabevorrichtung und verwendungsverfahren |
CA3082192A1 (en) | 2017-11-08 | 2019-05-16 | Pneuma Respiratory, Inc. | Electronic breath actuated in-line droplet delivery device with small volume ampoule and methods of use |
US20210106772A1 (en) * | 2018-04-02 | 2021-04-15 | Pneuma Respiratory, Inc. | Handheld digital nebulizer device and methods of use |
US11071842B2 (en) | 2018-07-09 | 2021-07-27 | Perma Pure Llc | Low-flow oxygen therapy humidifier and method |
WO2022160197A1 (zh) * | 2021-01-28 | 2022-08-04 | 深圳麦科田生物医疗技术股份有限公司 | 自动换药雾化装置 |
US11793945B2 (en) | 2021-06-22 | 2023-10-24 | Pneuma Respiratory, Inc. | Droplet delivery device with push ejection |
CN113577466B (zh) * | 2021-09-02 | 2022-03-01 | 平远县中医医院(平远县中医医院医共体总院) | 雾化吸入装置 |
Family Cites Families (89)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3812854A (en) * | 1972-10-20 | 1974-05-28 | A Michaels | Ultrasonic nebulizer |
US3923043A (en) * | 1973-09-28 | 1975-12-02 | Roman L Yanda | Method for acquisition of exhalation tidal volume and minute ventilation data |
US4468464A (en) * | 1974-11-04 | 1984-08-28 | The Board Of Trustees Of The Leland Stanford Junior University | Biologically functional molecular chimeras |
US3977394A (en) * | 1975-02-07 | 1976-08-31 | Jones Medical Instrument Company | Computerized pulmonary analyzer |
US3991304A (en) * | 1975-05-19 | 1976-11-09 | Hillsman Dean | Respiratory biofeedback and performance evaluation system |
US4153689A (en) * | 1975-06-13 | 1979-05-08 | Takeda Chemical Industries, Ltd. | Stable insulin preparation for nasal administration |
US4106503A (en) * | 1977-03-11 | 1978-08-15 | Richard R. Rosenthal | Metering system for stimulating bronchial spasm |
US4361401A (en) * | 1978-05-22 | 1982-11-30 | Instrumentation Laboratory Inc. | Automatic sample deposition in flameless analysis |
US4727028A (en) * | 1981-06-22 | 1988-02-23 | Eli Lilly And Company | Recombinant DNA cloning vectors and the eukaryotic and prokaryotic transformants thereof |
US4343798A (en) * | 1981-06-23 | 1982-08-10 | The Procter & Gamble Company | Topical antimicrobial anti-inflammatory compositions |
GB2104393B (en) * | 1981-08-13 | 1984-11-07 | Glaxo Group Ltd | Medical inhalation devices |
LU85034A1 (fr) * | 1982-10-08 | 1985-06-19 | Glaxo Group Ltd | Dispositifs en vue d'administrer des medicaments a des patients |
JPS608225A (ja) * | 1983-06-29 | 1985-01-17 | Kowa Co | 腸管吸収医薬組成物 |
US4604847A (en) * | 1983-09-14 | 1986-08-12 | Moulding Jr Thomas S | Medicine package, method of opening the package, and machine for performing the method |
DD230730A3 (de) * | 1984-01-02 | 1985-12-11 | Zentralinstitut Fuer Diabetes | Einrichtung zur prospektiven automatischen bestimmung individualspezifischer glukoseregulationsparameter |
US4624251A (en) * | 1984-09-13 | 1986-11-25 | Riker Laboratories, Inc. | Apparatus for administering a nebulized substance |
FI76929C (fi) | 1984-09-25 | 1989-01-10 | Etelae Haemeen Keuhkovammayhdi | Inhalationsdoseringsanordning, som aer avsedd foer nogrann dosering av disponerande laekemedel som ges aot andningssjuka i undersoekningsskedet och/eller laekemedel som ges som spray under behandlingen. |
NZ209900A (en) * | 1984-10-16 | 1989-08-29 | Univ Auckland | Automatic inhaler |
US4648393A (en) * | 1984-11-02 | 1987-03-10 | Ackrad Laboratories, Inc. | Breath activated medication spray |
IL78425A (en) * | 1985-04-15 | 1991-05-12 | Lilly Co Eli | Intranasal formulation containing insulin |
US4686231A (en) * | 1985-12-12 | 1987-08-11 | Smithkline Beckman Corporation | Inhibition of 5-lipoxygenase products |
NZ219021A (en) * | 1986-01-27 | 1989-06-28 | Gea Farmaceutisk Fabrik As | Inhaler: medicine discharged intermittently during each inhalation |
US4926852B1 (en) * | 1986-06-23 | 1995-05-23 | Univ Johns Hopkins | Medication delivery system phase one |
US4790305A (en) * | 1986-06-23 | 1988-12-13 | The Johns Hopkins University | Medication delivery system |
DE3627222A1 (de) * | 1986-08-11 | 1988-02-18 | Siemens Ag | Ultraschall-taschenzerstaeubergeraet |
US5108131A (en) * | 1986-10-07 | 1992-04-28 | Mainframe Data Limited | Method of controlling transmission of defects |
DE3636669C2 (de) * | 1986-10-28 | 2001-08-16 | Siemens Ag | Anordnung zur Zufuhr von Aerosol zu den Luftwegen und/oder Lungen eines Patienten |
US5126257A (en) * | 1986-11-26 | 1992-06-30 | Cornell Research Foundation | Antimicrobial proteins, compositions containing same and uses thereof |
US4796614A (en) * | 1987-02-26 | 1989-01-10 | Trutek Research, Inc. | Collapsible inhalation valve |
WO1989001486A1 (en) * | 1987-08-11 | 1989-02-23 | New York University | Biologically active bactericidal/permeability-increasing protein fragments |
US5198541A (en) * | 1987-08-11 | 1993-03-30 | New York University | Dna encoding bactericidal/permeability-increasing proteins |
US4852582A (en) * | 1987-09-11 | 1989-08-01 | Pell Donald M | Method and kit for measuring the effectiveness of bronchodilators |
US4907581A (en) * | 1988-06-30 | 1990-03-13 | Medi-Nuclear Corporation, Inc. | Radioactive aerosol inhalation apparatus |
GB8815978D0 (en) * | 1988-07-05 | 1988-08-10 | British Telecomm | Method & apparatus for encoding decoding & transmitting data in compressed form |
US4984158A (en) * | 1988-10-14 | 1991-01-08 | Hillsman Dean | Metered dose inhaler biofeedback training and evaluation system |
US5006343A (en) * | 1988-12-29 | 1991-04-09 | Benson Bradley J | Pulmonary administration of pharmaceutically active substances |
US5011678A (en) * | 1989-02-01 | 1991-04-30 | California Biotechnology Inc. | Composition and method for administration of pharmaceutically active substances |
US5514646A (en) * | 1989-02-09 | 1996-05-07 | Chance; Ronald E. | Insulin analogs modified at position 29 of the B chain |
US5171739A (en) * | 1989-02-14 | 1992-12-15 | Incyte Pharmaceuticals, Inc. | Treatment of endotoxin-associated shock and preventation thereof using a BPI protein |
WO1990012814A1 (en) * | 1989-04-20 | 1990-11-01 | Mount Sinai School Of Medicine Of The City University Of New York | Hepatospecific insulin analogues |
FR2654755B2 (fr) * | 1989-05-22 | 1993-04-30 | Baumann Felix | Perfectionnement aux cylindres secheurs dans les installations de fabrication de papier. |
JPH0371816A (ja) * | 1989-08-11 | 1991-03-27 | Komatsu Ltd | 射出プレス複合成形機のノズルタッチ機構 |
JPH0399667A (ja) | 1989-09-14 | 1991-04-24 | Terumo Corp | 医療用容器 |
US5152456A (en) | 1989-12-12 | 1992-10-06 | Bespak, Plc | Dispensing apparatus having a perforate outlet member and a vibrating device |
SG45171A1 (en) * | 1990-03-21 | 1998-01-16 | Boehringer Ingelheim Int | Atomising devices and methods |
US5192548A (en) * | 1990-04-30 | 1993-03-09 | Riker Laboratoires, Inc. | Device |
WO1991016929A1 (en) * | 1990-05-10 | 1991-11-14 | Novo Nordisk A/S | A pharmaceutical preparation containing n-glycofurols and n-ethylene glycols |
GB9015845D0 (en) * | 1990-07-19 | 1990-09-05 | Emery Vincent C | Diagnostic method |
GB9016789D0 (en) | 1990-07-31 | 1990-09-12 | Lilly Industries Ltd | Medicament administering devices |
US5230884A (en) * | 1990-09-11 | 1993-07-27 | University Of Wales College Of Cardiff | Aerosol formulations including proteins and peptides solubilized in reverse micelles and process for making the aerosol formulations |
GB9023282D0 (en) * | 1990-10-25 | 1990-12-05 | Riker Laboratories Inc | Inhalation device |
GB9026025D0 (en) * | 1990-11-29 | 1991-01-16 | Boehringer Ingelheim Kg | Inhalation device |
FR2673142A1 (fr) * | 1991-02-21 | 1992-08-28 | Ribal Annick | Dispositif de soudure autonome, portatif pour poches plastiques. |
US5404871A (en) * | 1991-03-05 | 1995-04-11 | Aradigm | Delivery of aerosol medications for inspiration |
US5394866A (en) * | 1991-03-05 | 1995-03-07 | Aradigm Corporation | Automatic aerosol medication delivery system and methods |
US5450336A (en) * | 1991-03-05 | 1995-09-12 | Aradigm Corporation | Method for correcting the drift offset of a transducer |
GB9109064D0 (en) * | 1991-04-26 | 1991-06-12 | Dunne Miller Weston Ltd | Dispensing device |
US5327883A (en) * | 1991-05-20 | 1994-07-12 | Dura Pharmaceuticals, Inc. | Apparatus for aerosolizing powdered medicine and process and using |
JP2525299B2 (ja) | 1991-07-26 | 1996-08-14 | ティーディーケイ株式会社 | 超音波霧化器 |
JPH05317041A (ja) * | 1991-06-05 | 1993-12-03 | Nippon Oil Co Ltd | 動物細胞増殖促進剤及び無血清培地 |
AU662919B2 (en) * | 1991-07-02 | 1995-09-21 | Inhale, Inc. | Method and device for delivering aerosolized medicaments |
US5268453A (en) * | 1991-08-08 | 1993-12-07 | Scios Inc. | Tissue-selective insulin analogs |
US5167506A (en) * | 1991-10-24 | 1992-12-01 | Minnesota Mining And Manufacturing Company | Inhalation device training system |
US5363842A (en) * | 1991-12-20 | 1994-11-15 | Circadian, Inc. | Intelligent inhaler providing feedback to both patient and medical professional |
US5320094A (en) * | 1992-01-10 | 1994-06-14 | The Johns Hopkins University | Method of administering insulin |
EP0558879B1 (de) * | 1992-03-04 | 1997-05-14 | Astra Aktiebolag | Wegwerfinhalator |
US5284133A (en) * | 1992-07-23 | 1994-02-08 | Armstrong Pharmaceuticals, Inc. | Inhalation device with a dose-timer, an actuator mechanism, and patient compliance monitoring means |
US5333106A (en) * | 1992-10-09 | 1994-07-26 | Circadian, Inc. | Apparatus and visual display method for training in the power use of aerosol pharmaceutical inhalers |
US6131567A (en) * | 1993-01-29 | 2000-10-17 | Aradigm Corporation | Method of use of monomeric insulin as a means for improving the reproducibility of inhaled insulin |
US7448375B2 (en) * | 1993-01-29 | 2008-11-11 | Aradigm Corporation | Method of treating diabetes mellitus in a patient |
US6024090A (en) * | 1993-01-29 | 2000-02-15 | Aradigm Corporation | Method of treating a diabetic patient by aerosolized administration of insulin lispro |
US5915378A (en) * | 1993-01-29 | 1999-06-29 | Aradigm Corporation | Creating an aerosolized formulation of insulin |
US5888477A (en) * | 1993-01-29 | 1999-03-30 | Aradigm Corporation | Use of monomeric insulin as a means for improving the bioavailability of inhaled insulin |
US5558085A (en) * | 1993-01-29 | 1996-09-24 | Aradigm Corporation | Intrapulmonary delivery of peptide drugs |
US5672581A (en) * | 1993-01-29 | 1997-09-30 | Aradigm Corporation | Method of administration of insulin |
US5364838A (en) * | 1993-01-29 | 1994-11-15 | Miris Medical Corporation | Method of administration of insulin |
US5743250A (en) * | 1993-01-29 | 1998-04-28 | Aradigm Corporation | Insulin delivery enhanced by coached breathing |
US5497763A (en) * | 1993-05-21 | 1996-03-12 | Aradigm Corporation | Disposable package for intrapulmonary delivery of aerosolized formulations |
FR2705911B1 (fr) * | 1993-06-02 | 1995-08-11 | Oreal | Appareil de nébulisation piézoélectrique. |
US5437267A (en) * | 1993-08-03 | 1995-08-01 | Weinstein; Allan | Device for delivering aerosol to the nasal membranes and method of use |
US5461031A (en) * | 1994-06-16 | 1995-10-24 | Eli Lilly And Company | Monomeric insulin analog formulations |
SE9402237D0 (sv) * | 1994-06-23 | 1994-06-23 | Astra Ab | Measurement methods and systems |
US5509404A (en) * | 1994-07-11 | 1996-04-23 | Aradigm Corporation | Intrapulmonary drug delivery within therapeutically relevant inspiratory flow/volume values |
US5547929A (en) * | 1994-09-12 | 1996-08-20 | Eli Lilly And Company | Insulin analog formulations |
US5522385A (en) * | 1994-09-27 | 1996-06-04 | Aradigm Corporation | Dynamic particle size control for aerosolized drug delivery |
US5758637A (en) * | 1995-08-31 | 1998-06-02 | Aerogen, Inc. | Liquid dispensing apparatus and methods |
US5694920A (en) * | 1996-01-25 | 1997-12-09 | Abrams; Andrew L. | Inhalation device |
US6131570A (en) * | 1998-06-30 | 2000-10-17 | Aradigm Corporation | Temperature controlling device for aerosol drug delivery |
US6694975B2 (en) * | 1996-11-21 | 2004-02-24 | Aradigm Corporation | Temperature controlling device for aerosol drug delivery |
-
1997
- 1997-01-31 US US08/792,616 patent/US5888477A/en not_active Expired - Lifetime
- 1997-04-25 US US08/846,243 patent/US5884620A/en not_active Expired - Lifetime
-
1998
- 1998-04-23 EP EP98919861A patent/EP1011767B1/de not_active Expired - Lifetime
- 1998-04-23 JP JP54714398A patent/JP2002504833A/ja active Pending
- 1998-04-23 AT AT98919861T patent/ATE308356T1/de not_active IP Right Cessation
- 1998-04-23 EP EP20050013890 patent/EP1576978B1/de not_active Expired - Lifetime
- 1998-04-23 DE DE69832183T patent/DE69832183T2/de not_active Expired - Lifetime
- 1998-04-23 ES ES05013890T patent/ES2321951T3/es not_active Expired - Lifetime
- 1998-04-23 AU AU72556/98A patent/AU741913B2/en not_active Ceased
- 1998-04-23 WO PCT/US1998/008238 patent/WO1998048873A1/en active IP Right Grant
- 1998-04-23 DE DE69840638T patent/DE69840638D1/de not_active Expired - Lifetime
- 1998-04-24 AR ARP980101907 patent/AR007491A1/es active IP Right Grant
- 1998-09-25 US US09/160,909 patent/US5941240A/en not_active Expired - Fee Related
-
1999
- 1999-08-20 US US09/378,638 patent/US6167880B1/en not_active Expired - Fee Related
-
2001
- 2001-09-10 US US09/950,562 patent/US6688304B2/en not_active Expired - Fee Related
-
2003
- 2003-11-04 US US10/701,967 patent/US7028686B2/en not_active Expired - Fee Related
-
2006
- 2006-01-31 US US11/345,061 patent/US20060124125A1/en not_active Abandoned
-
2007
- 2007-10-26 US US11/925,399 patent/US20080099011A1/en not_active Abandoned
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US20060124125A1 (en) | 2006-06-15 |
EP1576978B1 (de) | 2009-03-04 |
US6167880B1 (en) | 2001-01-02 |
US20020046750A1 (en) | 2002-04-25 |
DE69832183T2 (de) | 2006-08-03 |
EP1011767A1 (de) | 2000-06-28 |
US7028686B2 (en) | 2006-04-18 |
EP1011767B1 (de) | 2005-11-02 |
US5888477A (en) | 1999-03-30 |
DE69840638D1 (de) | 2009-04-16 |
ATE308356T1 (de) | 2005-11-15 |
US6688304B2 (en) | 2004-02-10 |
WO1998048873A1 (en) | 1998-11-05 |
AU741913B2 (en) | 2001-12-13 |
EP1011767A4 (de) | 2001-03-14 |
US20040089290A1 (en) | 2004-05-13 |
EP1576978A2 (de) | 2005-09-21 |
AR007491A1 (es) | 1999-11-10 |
JP2002504833A (ja) | 2002-02-12 |
EP1576978A3 (de) | 2005-11-30 |
US5941240A (en) | 1999-08-24 |
AU7255698A (en) | 1998-11-24 |
ES2321951T3 (es) | 2009-06-15 |
US20080099011A1 (en) | 2008-05-01 |
US5884620A (en) | 1999-03-23 |
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