DE69814635D1 - Verfahren zur herstellung von 2-hydroxybenzamidderivaten - Google Patents

Verfahren zur herstellung von 2-hydroxybenzamidderivaten

Info

Publication number
DE69814635D1
DE69814635D1 DE69814635T DE69814635T DE69814635D1 DE 69814635 D1 DE69814635 D1 DE 69814635D1 DE 69814635 T DE69814635 T DE 69814635T DE 69814635 T DE69814635 T DE 69814635T DE 69814635 D1 DE69814635 D1 DE 69814635D1
Authority
DE
Germany
Prior art keywords
producing
hydroxybenzamide derivatives
hydroxybenzamide
derivatives
chem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69814635T
Other languages
English (en)
Other versions
DE69814635T2 (de
Inventor
Ltd Nagasawa
Pharmaceutical Co Osato- Zeria
Ltd Nishioka
Ltd Suzuki
Pharmaceutical Co Osaato Zeria
Ltd Nagano
Pharmaceutical Co Osat Zeria
Ltd Ishii
Ltd Nakao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zeria Pharmaceutical Co Ltd
Original Assignee
Zeria Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP18184497A external-priority patent/JP4078687B2/ja
Priority claimed from JP25010697A external-priority patent/JP4078690B2/ja
Application filed by Zeria Pharmaceutical Co Ltd filed Critical Zeria Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE69814635D1 publication Critical patent/DE69814635D1/de
Publication of DE69814635T2 publication Critical patent/DE69814635T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69814635T 1997-06-24 1998-06-22 Verfahren zur herstellung von 2-hydroxybenzamidderivaten Expired - Lifetime DE69814635T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP18184497 1997-06-24
JP18184497A JP4078687B2 (ja) 1997-06-24 1997-06-24 ２−ヒドロキシ安息香酸アミド誘導体の製造法
JP25010697 1997-09-01
JP25010697A JP4078690B2 (ja) 1997-09-01 1997-09-01 アミノチアゾール誘導体の製造法
PCT/JP1998/002764 WO1998058918A1 (fr) 1997-06-24 1998-06-22 Procede de production des derives de 2-hydroxybenzamide

Publications (2)

Publication Number Publication Date
DE69814635D1 true DE69814635D1 (de) 2003-06-18
DE69814635T2 DE69814635T2 (de) 2004-03-11

Family

ID=26500852

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69814635T Expired - Lifetime DE69814635T2 (de) 1997-06-24 1998-06-22 Verfahren zur herstellung von 2-hydroxybenzamidderivaten

Country Status (12)

Country Link
US (1) US6197970B1 (de)
EP (1) EP0994108B1 (de)
KR (1) KR100528386B1 (de)
CN (1) CN1084739C (de)
AT (1) ATE240305T1 (de)
AU (1) AU725155B2 (de)
CA (1) CA2293361C (de)
DE (1) DE69814635T2 (de)
DK (1) DK0994108T3 (de)
ES (1) ES2198719T3 (de)
PT (1) PT994108E (de)
WO (1) WO1998058918A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3788935B2 (ja) * 2000-05-03 2006-06-21 エフ．ホフマン−ラ ロシュ アーゲー アルキニルフェニルヘテロ芳香族グルコキナーゼ活性化物質
EP1315488B1 (de) 2000-09-08 2006-10-25 Zeria Pharmaceutical Co., Ltd. Pharmazeutische zusammensetzungen enthaltend aminothiazole derivate zur behandlung von motorischen störungen des dickdarms
US20050143581A1 (en) * 2002-03-20 2005-06-30 Mitsui Chemicals, Inc. Process for preparation of alkoxybenzamides and thiazolyl isocyanates
SI1493441T1 (sl) * 2002-04-08 2011-12-30 Zeria Pharm Co Ltd Terapevtsko sredstvo za motnjo prilagoditve Ĺľelodca na zauĹľito prehrano
US7645353B2 (en) * 2003-12-23 2010-01-12 Kimberly-Clark Worldwide, Inc. Ultrasonically laminated multi-ply fabrics
SI1792888T1 (sl) * 2004-08-23 2011-10-28 Zeria Pharm Co Ltd Postopek za proizvajanje aminotiazolnega derivata in proizvodni intermediat
US8586761B2 (en) 2004-08-23 2013-11-19 Zeria Pharmaceutical Co., Ltd. Method for producing aminothiazole derivative and production intermediate
CA2580725A1 (en) * 2004-09-20 2006-03-30 4Sc Ag Novel heterocyclic nf-kb inhibitors
CN103387494B (zh) * 2012-05-10 2016-08-03 上海医药工业研究院 制备2-羟基-4,5-二甲氧基苯甲酸的方法
CN103387552B (zh) * 2012-05-10 2016-06-08 常州市第四制药厂有限公司 制备盐酸阿考替胺的方法
CN103896873B (zh) * 2013-10-23 2015-11-25 山东诚创医药技术开发有限公司 一种盐酸阿考替胺的精制方法
CN104592147A (zh) * 2013-10-30 2015-05-06 江苏豪森药业股份有限公司 盐酸阿考替胺中间体的制备方法
CN103665023B (zh) * 2013-12-23 2017-05-24 华润赛科药业有限责任公司 一种盐酸阿考替胺的合成方法
CN103709120B (zh) * 2014-01-20 2016-01-20 华润赛科药业有限责任公司 一种盐酸阿考替胺三水合物的制备方法
CN103980226A (zh) * 2014-05-10 2014-08-13 杭州新博思生物医药有限公司 盐酸阿考替胺水合物晶型及其制备方法
CN104031001B (zh) * 2014-06-30 2015-09-30 山东诚创医药技术开发有限公司 一锅烩制备2-[n-(2,4,5-三甲氧基苯甲胺基)氨基]-4-乙氧羰基-1,3-噻唑的方法
CN104045606B (zh) * 2014-07-11 2015-09-30 杭州新博思生物医药有限公司 一锅法制备阿考替胺盐酸盐的方法
CN105924406B (zh) * 2016-05-04 2018-04-10 河北国龙制药有限公司 一种盐酸阿考替胺三水合物的制备方法
CN106316979B (zh) * 2016-08-22 2018-11-27 山东罗欣药业集团股份有限公司 一种盐酸阿考替胺的制备方法
CN111518052A (zh) * 2020-05-27 2020-08-11 廊坊市泽康医药科技有限公司 一种阿考替胺盐酸盐杂质的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5510478A (en) * 1994-11-30 1996-04-23 American Home Products Corporation 2-arylamidothiazole derivatives with CNS activity
AU699008B2 (en) * 1995-05-18 1998-11-19 Zeria Pharmaceutical Co., Ltd. Aminothiazole derivative, medicament containing the same, and intermediate for preperation of said compound
JPH0987282A (ja) * 1995-09-21 1997-03-31 Kyowa Hakko Kogyo Co Ltd チアゾール誘導体
ATE231137T1 (de) * 1996-10-24 2003-02-15 Zeria Pharm Co Ltd Substituierte benzoylthiazolderivate und sie enthaltende medikamente

Also Published As

Publication number Publication date
DK0994108T3 (da) 2003-08-18
CA2293361A1 (en) 1998-12-30
EP0994108A4 (de) 2001-07-04
ATE240305T1 (de) 2003-05-15
WO1998058918A1 (fr) 1998-12-30
EP0994108A1 (de) 2000-04-19
CN1084739C (zh) 2002-05-15
CN1261357A (zh) 2000-07-26
AU8037298A (en) 1999-01-04
DE69814635T2 (de) 2004-03-11
ES2198719T3 (es) 2004-02-01
US6197970B1 (en) 2001-03-06
EP0994108B1 (de) 2003-05-14
AU725155B2 (en) 2000-10-05
PT994108E (pt) 2003-09-30
CA2293361C (en) 2006-06-20
KR100528386B1 (ko) 2005-11-15
KR20010013754A (ko) 2001-02-26

Similar Documents

Publication Publication Date Title
DE69814635D1 (de) Verfahren zur herstellung von 2-hydroxybenzamidderivaten
ATE282020T1 (de) Verfahren zur herstellung von 2-aminomalonsäure- derivaten
ATE174903T1 (de) Neues verfahren zur herstellung von 7- (substituierten)-9-((substistuierter
ATE207884T1 (de) Verfahren zur herstellung von aminobenzol- derivaten
ATE199709T1 (de) Verfahren zur herstellung von (+)compactin und (+)mevinolin derivaten mit beta-hydroxy-delta- lactonresten
DE69231815T2 (de) Verfahren zur Herstellung von Cephalosporinen und Zwischenprodukte in diesem Verfahren
ATE210136T1 (de) Verfahren zur herstellung von alkylhydrogenchlorsilanen
ATE218131T1 (de) Verfahren zur herstellung von mono-n- substituierten tetraazamakrocyclen
ATE176784T1 (de) Verfahren zur herstellung von n- biphenylmethylthiadiazolin derivaten oder deren salzen sowie dafür benötigte zwischen verbindungen
DE69115090D1 (de) Verfahren zur Herstellung von Fluormethyl-substituierten Pyridin-carbodithioaten.
ATE233267T1 (de) Verfahren zur herstellung von 3- vinylcephalosporinen
DE59809481D1 (de) Verfahren zur Herstellung von Aminocyanacetamid
ATE200776T1 (de) Verfahren zur herstellung von 2,4,5-tribrompyrrol-3-carbonitril
ATE139765T1 (de) Verfahren zur herstellung von halogenanthranilsäuren
ATE299498T1 (de) Verfahren zur herstellung von imidazolderivaten
ATE311382T1 (de) Verfahren zur herstellung von 2-carbamoyl- pyridinen
DE69127960D1 (de) Verfahren zur Herstellung von (S)-vinyl- und (S)-allenyl-Gaba
ATE240937T1 (de) Gamma-oxohomophenylalanin derivate und ein verfahren zur herstellung von homophenylalanin derivaten durch reduktion derselben
ATE175959T1 (de) Verfahren zur herstellung von azaphenothiazinen
DE69520554T2 (de) Verfahren zur herstellung von indolocarbazol-derivaten
ATE248841T1 (de) Verfahren zur herstellung von penicilling- phenylester
ATE208388T1 (de) Eintopfverfahren zur herstellung von 2- oxazolidinonderivate
DE59502722D1 (de) Verfahren und Zwischenprodukte zur Herstellung von 5-Oxaspiro [2.4] heptan-6-on
DE69914763D1 (de) Verfahren zur herstellung einer 2-aminobenzophenonverbindung

Legal Events

Date Code Title Description
8364 No opposition during term of opposition