DK0994108T3 - Fremgangsmåde til fremstilling af 2-hydroxybenzamidderivater - Google Patents

Fremgangsmåde til fremstilling af 2-hydroxybenzamidderivater

Info

Publication number
DK0994108T3
DK0994108T3 DK98928606T DK98928606T DK0994108T3 DK 0994108 T3 DK0994108 T3 DK 0994108T3 DK 98928606 T DK98928606 T DK 98928606T DK 98928606 T DK98928606 T DK 98928606T DK 0994108 T3 DK0994108 T3 DK 0994108T3
Authority
DK
Denmark
Prior art keywords
preparation
hydroxybenzamide derivatives
hydroxybenzamide
derivatives
chem
Prior art date
Application number
DK98928606T
Other languages
English (en)
Inventor
Masaaki Nagasawa
Hiroyasu Nishioka
Takanori Suzuki
Eiichi Nagano
Katsuyuki Ishii
Ryu Nakao
Original Assignee
Zeria Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP18184497A external-priority patent/JP4078687B2/ja
Priority claimed from JP25010697A external-priority patent/JP4078690B2/ja
Application filed by Zeria Pharm Co Ltd filed Critical Zeria Pharm Co Ltd
Application granted granted Critical
Publication of DK0994108T3 publication Critical patent/DK0994108T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
DK98928606T 1997-06-24 1998-06-22 Fremgangsmåde til fremstilling af 2-hydroxybenzamidderivater DK0994108T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP18184497A JP4078687B2 (ja) 1997-06-24 1997-06-24 ２−ヒドロキシ安息香酸アミド誘導体の製造法
JP25010697A JP4078690B2 (ja) 1997-09-01 1997-09-01 アミノチアゾール誘導体の製造法
PCT/JP1998/002764 WO1998058918A1 (fr) 1997-06-24 1998-06-22 Procede de production des derives de 2-hydroxybenzamide

Publications (1)

Publication Number Publication Date
DK0994108T3 true DK0994108T3 (da) 2003-08-18

Family

ID=26500852

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98928606T DK0994108T3 (da) 1997-06-24 1998-06-22 Fremgangsmåde til fremstilling af 2-hydroxybenzamidderivater

Country Status (12)

Country Link
US (1) US6197970B1 (da)
EP (1) EP0994108B1 (da)
KR (1) KR100528386B1 (da)
CN (1) CN1084739C (da)
AT (1) ATE240305T1 (da)
AU (1) AU725155B2 (da)
CA (1) CA2293361C (da)
DE (1) DE69814635T2 (da)
DK (1) DK0994108T3 (da)
ES (1) ES2198719T3 (da)
PT (1) PT994108E (da)
WO (1) WO1998058918A1 (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2407416C (en) * 2000-05-03 2006-07-18 Paige Erin Mahaney Alkynyl phenyl heteroaromatic glucokinase activators
KR100776298B1 (ko) 2000-09-08 2007-11-13 제리아 신야쿠 고교 가부시키 가이샤 아미노티아졸 유도체를 유효성분으로 하는 대장 운동 부전치료제
EP1489073A4 (en) * 2002-03-20 2006-03-29 Mitsui Chemicals Inc PROCESS FOR THE PREPARATION OF ALKOXYBENZAMIDES AND THIAZOLYL ISOCYANATES
KR101423284B1 (ko) * 2002-04-08 2014-07-24 제리아 신야쿠 고교 가부시키 가이샤 위 음식물 수용능 장해 치료약
US7645353B2 (en) * 2003-12-23 2010-01-12 Kimberly-Clark Worldwide, Inc. Ultrasonically laminated multi-ply fabrics
US8586761B2 (en) 2004-08-23 2013-11-19 Zeria Pharmaceutical Co., Ltd. Method for producing aminothiazole derivative and production intermediate
DK1792888T3 (da) 2004-08-23 2011-10-10 Zeria Pharm Co Ltd Fremgangsmåde til fremstilling af et aminothiazol-derivat og mellemprodukt
BRPI0516958A (pt) * 2004-09-20 2008-03-25 4Sc Ag inibidores da nf-capab heterocìclicos
CN103387552B (zh) * 2012-05-10 2016-06-08 常州市第四制药厂有限公司 制备盐酸阿考替胺的方法
CN103387494B (zh) * 2012-05-10 2016-08-03 上海医药工业研究院 制备2-羟基-4,5-二甲氧基苯甲酸的方法
CN103896873B (zh) * 2013-10-23 2015-11-25 山东诚创医药技术开发有限公司 一种盐酸阿考替胺的精制方法
CN104592147A (zh) * 2013-10-30 2015-05-06 江苏豪森药业股份有限公司 盐酸阿考替胺中间体的制备方法
CN103665023B (zh) * 2013-12-23 2017-05-24 华润赛科药业有限责任公司 一种盐酸阿考替胺的合成方法
CN103709120B (zh) * 2014-01-20 2016-01-20 华润赛科药业有限责任公司 一种盐酸阿考替胺三水合物的制备方法
CN103980226A (zh) * 2014-05-10 2014-08-13 杭州新博思生物医药有限公司 盐酸阿考替胺水合物晶型及其制备方法
CN104031001B (zh) * 2014-06-30 2015-09-30 山东诚创医药技术开发有限公司 一锅烩制备2-[n-(2,4,5-三甲氧基苯甲胺基)氨基]-4-乙氧羰基-1,3-噻唑的方法
CN104045606B (zh) * 2014-07-11 2015-09-30 杭州新博思生物医药有限公司 一锅法制备阿考替胺盐酸盐的方法
CN105924406B (zh) * 2016-05-04 2018-04-10 河北国龙制药有限公司 一种盐酸阿考替胺三水合物的制备方法
CN106316979B (zh) * 2016-08-22 2018-11-27 山东罗欣药业集团股份有限公司 一种盐酸阿考替胺的制备方法
CN111518052A (zh) * 2020-05-27 2020-08-11 廊坊市泽康医药科技有限公司 一种阿考替胺盐酸盐杂质的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5510478A (en) * 1994-11-30 1996-04-23 American Home Products Corporation 2-arylamidothiazole derivatives with CNS activity
ATE254609T1 (de) * 1995-05-18 2003-12-15 Zeria Pharm Co Ltd Aminothiazolderivate, sie enthaltende arzneimittel und zwischenprodukte in der herstellung dieser verbindungen
JPH0987282A (ja) * 1995-09-21 1997-03-31 Kyowa Hakko Kogyo Co Ltd チアゾール誘導体
US6121301A (en) * 1996-10-24 2000-09-19 Zeria Pharmaceutical Co., Ltd. Substituted benzoylaminothiazole derivatives and drugs containing the same

Also Published As

Publication number Publication date
DE69814635T2 (de) 2004-03-11
AU8037298A (en) 1999-01-04
DE69814635D1 (de) 2003-06-18
WO1998058918A1 (fr) 1998-12-30
KR20010013754A (ko) 2001-02-26
KR100528386B1 (ko) 2005-11-15
US6197970B1 (en) 2001-03-06
PT994108E (pt) 2003-09-30
CN1084739C (zh) 2002-05-15
EP0994108A1 (en) 2000-04-19
ATE240305T1 (de) 2003-05-15
EP0994108A4 (en) 2001-07-04
CA2293361A1 (en) 1998-12-30
EP0994108B1 (en) 2003-05-14
ES2198719T3 (es) 2004-02-01
AU725155B2 (en) 2000-10-05
CN1261357A (zh) 2000-07-26
CA2293361C (en) 2006-06-20

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