ATE199709T1 - Verfahren zur herstellung von (+)compactin und (+)mevinolin derivaten mit beta-hydroxy-delta- lactonresten - Google Patents

Verfahren zur herstellung von (+)compactin und (+)mevinolin derivaten mit beta-hydroxy-delta- lactonresten

Info

Publication number
ATE199709T1
ATE199709T1 AT96938297T AT96938297T ATE199709T1 AT E199709 T1 ATE199709 T1 AT E199709T1 AT 96938297 T AT96938297 T AT 96938297T AT 96938297 T AT96938297 T AT 96938297T AT E199709 T1 ATE199709 T1 AT E199709T1
Authority
AT
Austria
Prior art keywords
compactin
delta
beta
hydroxy
lactone
Prior art date
Application number
AT96938297T
Other languages
English (en)
Inventor
Guy Solladie
Claude Bauder
Original Assignee
Oreal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oreal filed Critical Oreal
Application granted granted Critical
Publication of ATE199709T1 publication Critical patent/ATE199709T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/04—Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C07C317/46—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT96938297T 1995-11-28 1996-11-12 Verfahren zur herstellung von (+)compactin und (+)mevinolin derivaten mit beta-hydroxy-delta- lactonresten ATE199709T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9514093A FR2741620B1 (fr) 1995-11-28 1995-11-28 Procede de preparation de composes a groupement beta-hydroxy -delta-lactone analogues de la (+) compactine et de la (+) mevinoline
PCT/FR1996/001782 WO1997019917A1 (fr) 1995-11-28 1996-11-12 PROCEDE DE PREPARATION DE COMPOSES A GROUPEMENT β-HYDROXY-δ-LACTONE ANALOGUES DE LA (+) COMPACTINE ET DE LA (+) MEVINOLINE

Publications (1)

Publication Number Publication Date
ATE199709T1 true ATE199709T1 (de) 2001-03-15

Family

ID=9484968

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96938297T ATE199709T1 (de) 1995-11-28 1996-11-12 Verfahren zur herstellung von (+)compactin und (+)mevinolin derivaten mit beta-hydroxy-delta- lactonresten

Country Status (7)

Country Link
EP (1) EP0805800B1 (de)
JP (1) JP3119663B2 (de)
AT (1) ATE199709T1 (de)
DE (1) DE69612086T2 (de)
ES (1) ES2157466T3 (de)
FR (1) FR2741620B1 (de)
WO (1) WO1997019917A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0623580B2 (ja) * 1986-11-19 1994-03-30 株式会社三ッ葉電機製作所 スタータのクラッチのアウタとインナ間の開放端を閉塞するカバ−の固定構造及び固定方法
EP1323715B1 (de) * 1997-04-16 2004-06-30 The University of New Mexico Cholesterin Esterase Inhibitoren
EP0975617B1 (de) * 1997-04-16 2003-11-05 The University of New Mexico Inhibitoren der cholesterolesterase
GB9903472D0 (en) * 1999-02-17 1999-04-07 Zeneca Ltd Chemical process
GB0011120D0 (en) 2000-05-09 2000-06-28 Avecia Ltd Process
NL1015744C2 (nl) * 2000-07-19 2002-01-22 Dsm Nv Werkwijze voor de bereiding van 2-(6-gesubstitueerde-1,3-dioxan-4-yl) azijnzuurderivaten.
IL159741A0 (en) 2001-07-13 2004-06-20 Astrazeneca Uk Ltd Preparation of aminopyrimidine compounds
EP1323717A1 (de) 2001-12-27 2003-07-02 Dsm N.V. Prozess für die Herstellung von 2-(6-Substituierten-1,3-Dioxan-4-yl) Essigsäure Derivaten
DE60326832D1 (de) * 2002-04-12 2009-05-07 Mercian Corp Expressionssystem des aus actinomyceten stammenden cytochrom p-450 in escherichia coli
EP1375493A1 (de) 2002-06-17 2004-01-02 Dsm N.V. Verfahren zur Herstellung von Dioxanessigsäureester
GB0218781D0 (en) * 2002-08-13 2002-09-18 Astrazeneca Ab Chemical process
BR0317313A (pt) 2002-12-16 2005-11-08 Astrazeneca Uk Ltd Processo para a preparação de um composto, e, composto
GB0312896D0 (en) 2003-06-05 2003-07-09 Astrazeneca Ab Chemical process
UY28501A1 (es) 2003-09-10 2005-04-29 Astrazeneca Uk Ltd Compuestos químicos
GB0322552D0 (en) 2003-09-26 2003-10-29 Astrazeneca Uk Ltd Therapeutic treatment
GB0324791D0 (en) 2003-10-24 2003-11-26 Astrazeneca Ab Chemical process
GB0428328D0 (en) 2004-12-24 2005-02-02 Astrazeneca Uk Ltd Chemical process
WO2007125547A2 (en) 2006-05-03 2007-11-08 Manne Satyanarayana Reddy Novel process for statins and its pharmaceutically acceptable salts thereof
US8404841B2 (en) 2006-10-09 2013-03-26 Msn Laboratories Limited Process for the preparation of statins and their pharmaceutically acceptable salts thereof
EP2387561A4 (de) 2009-01-19 2012-07-25 Msn Lab Ltd Verbessertes verfahren zur herstellung von hochreiner (3r,5s)-7-[2-cyclopropyl-4-(4-fluorphenyl) chinolin-3-yl]-3,5-dihydroxy-6(e)-heptensäure und pharmazeutisch akzeptable salze daraus
EP2526099B1 (de) 2010-01-18 2016-03-30 MSN Laboratories Limited Verbessertes verfahren zur herstellung von amid-zwischenprodukten und seine anwendung

Also Published As

Publication number Publication date
DE69612086D1 (de) 2001-04-19
DE69612086T2 (de) 2001-06-21
JPH10504845A (ja) 1998-05-12
JP3119663B2 (ja) 2000-12-25
WO1997019917A1 (fr) 1997-06-05
EP0805800B1 (de) 2001-03-14
EP0805800A1 (de) 1997-11-12
FR2741620B1 (fr) 1997-12-26
FR2741620A1 (fr) 1997-05-30
ES2157466T3 (es) 2001-08-16

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee