DE69612086D1 - Verfahren zur herstellung von (+)compactin und (+)mevinolin derivaten mit beta-hydroxy-delta-lactonresten - Google Patents

Verfahren zur herstellung von (+)compactin und (+)mevinolin derivaten mit beta-hydroxy-delta-lactonresten

Info

Publication number
DE69612086D1
DE69612086D1 DE69612086T DE69612086T DE69612086D1 DE 69612086 D1 DE69612086 D1 DE 69612086D1 DE 69612086 T DE69612086 T DE 69612086T DE 69612086 T DE69612086 T DE 69612086T DE 69612086 D1 DE69612086 D1 DE 69612086D1
Authority
DE
Germany
Prior art keywords
compactin
delta
beta
hydroxy
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69612086T
Other languages
English (en)
Other versions
DE69612086T2 (de
Inventor
Guy Solladie
Claude Bauder
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LOreal SA
Original Assignee
LOreal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LOreal SA filed Critical LOreal SA
Application granted granted Critical
Publication of DE69612086D1 publication Critical patent/DE69612086D1/de
Publication of DE69612086T2 publication Critical patent/DE69612086T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/04—Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C07C317/46—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69612086T 1995-11-28 1996-11-12 Verfahren zur herstellung von (+)compactin und (+)mevinolin derivaten mit beta-hydroxy-delta-lactonresten Expired - Fee Related DE69612086T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9514093A FR2741620B1 (fr) 1995-11-28 1995-11-28 Procede de preparation de composes a groupement beta-hydroxy -delta-lactone analogues de la (+) compactine et de la (+) mevinoline
PCT/FR1996/001782 WO1997019917A1 (fr) 1995-11-28 1996-11-12 PROCEDE DE PREPARATION DE COMPOSES A GROUPEMENT β-HYDROXY-δ-LACTONE ANALOGUES DE LA (+) COMPACTINE ET DE LA (+) MEVINOLINE

Publications (2)

Publication Number Publication Date
DE69612086D1 true DE69612086D1 (de) 2001-04-19
DE69612086T2 DE69612086T2 (de) 2001-06-21

Family

ID=9484968

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69612086T Expired - Fee Related DE69612086T2 (de) 1995-11-28 1996-11-12 Verfahren zur herstellung von (+)compactin und (+)mevinolin derivaten mit beta-hydroxy-delta-lactonresten

Country Status (7)

Country Link
EP (1) EP0805800B1 (de)
JP (1) JP3119663B2 (de)
AT (1) ATE199709T1 (de)
DE (1) DE69612086T2 (de)
ES (1) ES2157466T3 (de)
FR (1) FR2741620B1 (de)
WO (1) WO1997019917A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0623580B2 (ja) * 1986-11-19 1994-03-30 株式会社三ッ葉電機製作所 スタータのクラッチのアウタとインナ間の開放端を閉塞するカバ−の固定構造及び固定方法
EP1323715B1 (de) * 1997-04-16 2004-06-30 The University of New Mexico Cholesterin Esterase Inhibitoren
ATE270284T1 (de) * 1997-04-16 2004-07-15 Univ New Mexico Cholesterin esterase inhibitoren
GB9903472D0 (en) * 1999-02-17 1999-04-07 Zeneca Ltd Chemical process
GB0011120D0 (en) 2000-05-09 2000-06-28 Avecia Ltd Process
NL1015744C2 (nl) * 2000-07-19 2002-01-22 Dsm Nv Werkwijze voor de bereiding van 2-(6-gesubstitueerde-1,3-dioxan-4-yl) azijnzuurderivaten.
AU2002318041B2 (en) 2001-07-13 2008-01-03 Astrazeneca Uk Limited Preparation of aminopyrimidine compounds
EP1323717A1 (de) 2001-12-27 2003-07-02 Dsm N.V. Prozess für die Herstellung von 2-(6-Substituierten-1,3-Dioxan-4-yl) Essigsäure Derivaten
ATE426671T1 (de) * 2002-04-12 2009-04-15 Mercian Corp Expressionssystem des aus actinomyceten stammenden cytochrom p-450 in escherichia coli
EP1375493A1 (de) 2002-06-17 2004-01-02 Dsm N.V. Verfahren zur Herstellung von Dioxanessigsäureester
GB0218781D0 (en) 2002-08-13 2002-09-18 Astrazeneca Ab Chemical process
ATE448209T1 (de) 2002-12-16 2009-11-15 Astrazeneca Uk Ltd Verfahren zur herstellung von pyrimidinverbindungen
GB0312896D0 (en) 2003-06-05 2003-07-09 Astrazeneca Ab Chemical process
UY28501A1 (es) 2003-09-10 2005-04-29 Astrazeneca Uk Ltd Compuestos químicos
GB0322552D0 (en) 2003-09-26 2003-10-29 Astrazeneca Uk Ltd Therapeutic treatment
GB0324791D0 (en) 2003-10-24 2003-11-26 Astrazeneca Ab Chemical process
GB0428328D0 (en) 2004-12-24 2005-02-02 Astrazeneca Uk Ltd Chemical process
US8455640B2 (en) 2006-05-03 2013-06-04 Msn Laboratories Limited Process for statins and its pharmaceutically acceptable salts thereof
HUE028475T2 (en) 2006-10-09 2016-12-28 Msn Laboratories Private Ltd A novel process for the preparation of statins and their pharmaceutically acceptable salts
EP2387561A4 (de) 2009-01-19 2012-07-25 Msn Lab Ltd Verbessertes verfahren zur herstellung von hochreiner (3r,5s)-7-[2-cyclopropyl-4-(4-fluorphenyl) chinolin-3-yl]-3,5-dihydroxy-6(e)-heptensäure und pharmazeutisch akzeptable salze daraus
US8987444B2 (en) 2010-01-18 2015-03-24 Msn Laboratories Private Limited Process for the preparation of amide intermediates and their use thereof

Also Published As

Publication number Publication date
JP3119663B2 (ja) 2000-12-25
ES2157466T3 (es) 2001-08-16
FR2741620A1 (fr) 1997-05-30
FR2741620B1 (fr) 1997-12-26
DE69612086T2 (de) 2001-06-21
JPH10504845A (ja) 1998-05-12
ATE199709T1 (de) 2001-03-15
EP0805800A1 (de) 1997-11-12
WO1997019917A1 (fr) 1997-06-05
EP0805800B1 (de) 2001-03-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee