DE69824901D1 - Cholesterin Esterase Inhibitoren - Google Patents
Cholesterin Esterase InhibitorenInfo
- Publication number
- DE69824901D1 DE69824901D1 DE69824901T DE69824901T DE69824901D1 DE 69824901 D1 DE69824901 D1 DE 69824901D1 DE 69824901 T DE69824901 T DE 69824901T DE 69824901 T DE69824901 T DE 69824901T DE 69824901 D1 DE69824901 D1 DE 69824901D1
- Authority
- DE
- Germany
- Prior art keywords
- cholesterol esterase
- esterase inhibitors
- inhibitors
- cholesterol
- present
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
- C07D309/38—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4198897P | 1997-04-16 | 1997-04-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69824901D1 true DE69824901D1 (de) | 2004-08-05 |
Family
ID=21919442
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69819482T Expired - Fee Related DE69819482T2 (de) | 1997-04-16 | 1998-04-15 | Inhibitoren der cholesterolesterase |
DE69824901T Expired - Lifetime DE69824901D1 (de) | 1997-04-16 | 1998-04-15 | Cholesterin Esterase Inhibitoren |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69819482T Expired - Fee Related DE69819482T2 (de) | 1997-04-16 | 1998-04-15 | Inhibitoren der cholesterolesterase |
Country Status (7)
Country | Link |
---|---|
US (3) | US5942631A (de) |
EP (1) | EP0975617B1 (de) |
JP (1) | JP2002512611A (de) |
AT (2) | ATE253565T1 (de) |
CA (1) | CA2284525A1 (de) |
DE (2) | DE69819482T2 (de) |
WO (1) | WO1998046585A1 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7115279B2 (en) * | 2000-08-03 | 2006-10-03 | Curatolo William J | Pharmaceutical compositions of cholesteryl ester transfer protein inhibitors |
WO2009086096A2 (en) * | 2007-12-21 | 2009-07-09 | University Of Cincinnati | Therapeutic use of carboxyl ester lipase inhibitors |
US9061796B2 (en) * | 2009-04-23 | 2015-06-23 | H.J. Heinz Company | Multi-function condiment container |
EP2844303B1 (de) | 2012-05-03 | 2021-09-15 | Beth Israel Deaconess Medical Center, Inc. | Lipide zur erhöhung der insulinempfindlichkeit und verfahren zur verwendung davon |
WO2014144777A2 (en) | 2013-03-15 | 2014-09-18 | Beth Israel Deaconess Medical Center, Inc. | Lipids that increase insulin sensitivity and methods of using the same |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3056802A (en) * | 1960-10-04 | 1962-10-02 | Union Carbide Corp | Alpha-halo lactones |
US3227736A (en) * | 1962-10-31 | 1966-01-04 | Olin Mathieson | Production of alpha-fluorocarboxylic acids and esters |
US3346594A (en) * | 1965-08-25 | 1967-10-10 | Gen Aniline & Film Corp | Haloalkyl and polyhaloalkyl lactones |
US4338122A (en) * | 1979-09-26 | 1982-07-06 | Union Carbide Corporation | Biocidal 2-aryl-1,3-cyclopentanedione compounds and alkali metal and ammonium salts thereof |
GB2168696B (en) * | 1984-12-21 | 1989-01-11 | Boehringer Biochemia Srl | Fluoro coumarins as antilymphoedema agents |
US5025017A (en) * | 1989-09-28 | 1991-06-18 | E. R. Squibb & Sons, Inc. | Seco-mevinic acid derivatives useful as antihypercholesterolemic agents and new intermediates |
US5059696A (en) * | 1990-03-15 | 1991-10-22 | Merck & Co., Inc. | Processes and intermediates for the preparation of 5-oxygenated hmg-coa reductase inhibitors |
GB9100174D0 (en) * | 1991-01-04 | 1991-02-20 | British Bio Technology | Compounds |
JP3159990B2 (ja) * | 1992-11-18 | 2001-04-23 | フイルメニツヒ ソシエテ アノニム | 香料成分としてのフラノンの使用 |
FR2741620B1 (fr) * | 1995-11-28 | 1997-12-26 | Oreal | Procede de preparation de composes a groupement beta-hydroxy -delta-lactone analogues de la (+) compactine et de la (+) mevinoline |
-
1998
- 1998-04-15 DE DE69819482T patent/DE69819482T2/de not_active Expired - Fee Related
- 1998-04-15 WO PCT/US1998/007263 patent/WO1998046585A1/en active IP Right Grant
- 1998-04-15 CA CA002284525A patent/CA2284525A1/en not_active Abandoned
- 1998-04-15 AT AT98918098T patent/ATE253565T1/de not_active IP Right Cessation
- 1998-04-15 AT AT03006153T patent/ATE270284T1/de not_active IP Right Cessation
- 1998-04-15 JP JP54411598A patent/JP2002512611A/ja active Pending
- 1998-04-15 US US09/060,250 patent/US5942631A/en not_active Expired - Fee Related
- 1998-04-15 DE DE69824901T patent/DE69824901D1/de not_active Expired - Lifetime
- 1998-04-15 EP EP98918098A patent/EP0975617B1/de not_active Expired - Lifetime
-
1999
- 1999-04-15 US US09/291,990 patent/US6034255A/en not_active Expired - Fee Related
- 1999-12-16 US US09/464,194 patent/US6114545A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2284525A1 (en) | 1998-10-22 |
US6114545A (en) | 2000-09-05 |
DE69819482D1 (de) | 2003-12-11 |
DE69819482T2 (de) | 2004-08-26 |
ATE253565T1 (de) | 2003-11-15 |
US5942631A (en) | 1999-08-24 |
US6034255A (en) | 2000-03-07 |
EP0975617A4 (de) | 2000-09-13 |
WO1998046585A1 (en) | 1998-10-22 |
ATE270284T1 (de) | 2004-07-15 |
EP0975617B1 (de) | 2003-11-05 |
EP0975617A1 (de) | 2000-02-02 |
JP2002512611A (ja) | 2002-04-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8332 | No legal effect for de |