DE69811105T2 - Pharmazeutische zubereitungen zur oralen verabreichung von molekulares jod - Google Patents

Pharmazeutische zubereitungen zur oralen verabreichung von molekulares jod

Info

Publication number
DE69811105T2
DE69811105T2 DE69811105T DE69811105T DE69811105T2 DE 69811105 T2 DE69811105 T2 DE 69811105T2 DE 69811105 T DE69811105 T DE 69811105T DE 69811105 T DE69811105 T DE 69811105T DE 69811105 T2 DE69811105 T2 DE 69811105T2
Authority
DE
Germany
Prior art keywords
iodine
iodide
compound
iodate
molecular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69811105T
Other languages
German (de)
English (en)
Other versions
DE69811105D1 (de
Inventor
Yongjun Duan
John Hickey
Jack Kessler
Rick Panicucci
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Symbollon Corp
Original Assignee
Symbollon Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Symbollon Corp filed Critical Symbollon Corp
Publication of DE69811105D1 publication Critical patent/DE69811105D1/de
Application granted granted Critical
Publication of DE69811105T2 publication Critical patent/DE69811105T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/18—Iodine; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/40—Peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69811105T 1997-10-29 1998-10-27 Pharmazeutische zubereitungen zur oralen verabreichung von molekulares jod Expired - Lifetime DE69811105T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/960,149 US5885592A (en) 1997-10-29 1997-10-29 Methods and pharmaceutical compositions for oral delivery of molecular iodine
PCT/US1998/022720 WO1999021567A1 (en) 1997-10-29 1998-10-27 Pharmaceutical compositions for oral administration of molecular iodine

Publications (2)

Publication Number Publication Date
DE69811105D1 DE69811105D1 (de) 2003-03-06
DE69811105T2 true DE69811105T2 (de) 2003-11-06

Family

ID=25502851

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69811105T Expired - Lifetime DE69811105T2 (de) 1997-10-29 1998-10-27 Pharmazeutische zubereitungen zur oralen verabreichung von molekulares jod

Country Status (17)

Country Link
US (1) US5885592A (OSRAM)
EP (1) EP1024815B1 (OSRAM)
JP (1) JP4187410B2 (OSRAM)
KR (1) KR100412219B1 (OSRAM)
CN (1) CN1150904C (OSRAM)
AT (1) ATE231725T1 (OSRAM)
AU (1) AU750627B2 (OSRAM)
BR (1) BR9812588A (OSRAM)
CA (1) CA2301503C (OSRAM)
DE (1) DE69811105T2 (OSRAM)
DK (1) DK1024815T3 (OSRAM)
ES (1) ES2191973T3 (OSRAM)
IL (1) IL134778A0 (OSRAM)
NO (1) NO20001673L (OSRAM)
PT (1) PT1024815E (OSRAM)
RU (1) RU2213564C2 (OSRAM)
WO (1) WO1999021567A1 (OSRAM)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6248335B1 (en) * 1997-10-29 2001-06-19 Symbollon Corporation Stabilized oral pharmaceutical composition containing iodide and iodate and method
EP1044689A4 (en) * 1998-01-06 2002-07-03 Fujisawa Pharmaceutical Co SOLID IODOPHORE BASED PREPARATIONS AND MANUFACTURING METHOD THEREOF
CN1306444A (zh) 1998-06-19 2001-08-01 奥西比奥公司 具有抗感染和避孕性能的医学装置
US6154672A (en) * 1998-06-22 2000-11-28 Pacesetter, Inc. Method and apparatus for improving the probability of success of defibrillation shocks
GB2395901A (en) * 1999-02-26 2004-06-09 Symbollon Corp Stabilised tablets containing iodide and iodate
PT1195178E (pt) * 2000-10-06 2006-10-31 Dmg Italia Srl Preparacao imunotrofica para o tratamento da hipertrofia adenoamigdalar.
RU2201229C1 (ru) * 2002-03-26 2003-03-27 Миронов Владимир Андреевич Способ оздоровления организма
US8501223B2 (en) * 2003-06-20 2013-08-06 Hill's Pet Nutrition, Inc. Methods for dietary management of cats to avoid hyperthyroidism
BRPI0411712B1 (pt) * 2003-06-20 2015-07-07 Hills Pet Nutrition Inc Composição com iodo reduzido embalada para dieta de felinos para restabelecer a função normal da tireóide
EP2666366B1 (en) * 2006-01-26 2015-03-11 Hill's Pet Nutrition, Inc. Methods and compositions for treating feline hyperthyroidism
US20090269416A1 (en) * 2006-05-12 2009-10-29 Hill's Pet Nutrition , Inc. Compositions and Methods For Preventing or Treating Chronic Renal Failure in Felines With Hyperthyroidism
US8303994B2 (en) * 2006-06-22 2012-11-06 Jack Howard Kessler Method for the eradication of pathogens including S. aureus and antibiotic resistant microbes from the upper respiratory tract of mammals and for inhibiting the activation of immune cells
EP2040565B1 (en) * 2006-07-03 2013-01-02 Hill's Pet Nutrition, Inc. Copositions and methods for preventing or treating cardiovascular diseases in felines with hyperthyroidism
US7943158B2 (en) * 2006-09-07 2011-05-17 BioLargo Life Technologies, Inc Absorbent systems providing antimicrobial activity
US7867510B2 (en) * 2006-09-07 2011-01-11 BioLargo Life Technologies, Inc Material having antimicrobial activity when wet
US20080063560A1 (en) * 2006-09-07 2008-03-13 Biolargo Life Technologies, Incorporated Ground treatment for reducing microbial content
US9414601B2 (en) * 2006-09-07 2016-08-16 Biolargo Life Technologies, Incorporated Material having antimicrobial activity when wet
US8226964B2 (en) * 2006-09-07 2012-07-24 Biolargo Life Technologies, Inc. Systems and methods for cleaning liquid carriers related applications data
US8021610B2 (en) * 2006-09-07 2011-09-20 Biolargo Life Technologies, Inc. Systems providing antimicrobial activity to an environment
US8257749B2 (en) * 2007-02-08 2012-09-04 Biolargo Life Technologies, Incorporated Systems providing at least pesticidal activity
WO2009087647A1 (en) * 2008-01-07 2009-07-16 Council Of Scientific & Industrial Research A stabilized iodine-water concentrate formulation useful for protection against iodine deficiency disorders
MX340005B (es) * 2010-04-23 2016-05-18 Univ Nac Autónoma De México Composicion de yodo molecular de uso humano para la prevencion y tratamiento de patologias prostaticas.
CN103561735B (zh) * 2011-05-16 2016-01-20 S·S·别尕里耶夫 具有抗菌、抗溃疡和免疫调节作用的药物制剂
CN102697804B (zh) * 2012-06-07 2014-02-12 维尔信科技（潍坊）有限公司 一种固态分子碘消毒制剂及其制备方法
US10034899B2 (en) * 2013-11-27 2018-07-31 BioPharmX, Inc. Solid oral dosage form for breast symptoms
ES2987484T3 (es) * 2014-02-10 2024-11-15 Fred Hutchinson Cancer Center Tratamiento de ataque cardiaco y lesión isquémica con yoduro de sodio
CN106163577A (zh) * 2014-03-31 2016-11-23 艾欧泰克国际股份有限公司 未络合的碘的稳定组合物以及使用方法
EA031907B1 (ru) * 2016-03-11 2019-03-29 Тимур Хусаинович Измайлов Шашка иодная дымовая
WO2017185060A1 (en) 2016-04-21 2017-10-26 BioPharmX, Inc. Oral iodine dosage form
MX2019000902A (es) 2016-07-21 2020-09-03 I2Pure Corp Desinfectantes topicos emolientes.
CN106727683A (zh) * 2016-12-23 2017-05-31 刘海涛 一种药物制剂在制备治疗幽门螺杆菌感染性疾病的药物中的应用
TW202203900A (zh) * 2020-03-31 2022-02-01 越南商泰明製藥股份有限公司 用於治療癌症、子宮內膜異位症以及癌症或子宮內膜異位症患者的疼痛之二異丙胺化合物以及碘
EP4196094A4 (en) 2020-08-13 2024-11-13 I2Pure Corp. High molecular iodine concentration compositions, pharmaceutical formulations, preparation and uses
WO2024201560A1 (en) * 2023-03-24 2024-10-03 Me.Link Co., Ltd. Iodine containing colloidal liquid composition

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2540170C3 (de) * 1975-09-10 1979-01-18 Basf Ag, 6700 Ludwigshafen Verwendung von in organischer Lösung hergestelltem Polyvinylpyrrolidon zur Herstellung von stabilen wäßrigen PoIyvinylpyrrolidon-Jod-Lösungen
US4259322A (en) * 1978-03-20 1981-03-31 Helong Lim Method of treatment of tuberculosis
US4187294A (en) * 1978-07-06 1980-02-05 Nihon Nousan Kougyou Co., Ltd. Method for producing eggs containing a high amount of iodinated amino acids
JPS5663919A (en) * 1979-10-29 1981-05-30 Nippon Nousan Kogyo Kk Remedial composition for diabetes
JPS57140723A (en) * 1981-02-25 1982-08-31 Nippon Nousan Kogyo Kk Preventing composition for hyperlipemia due to neutral fat
US4816255A (en) * 1985-07-31 1989-03-28 Ghent William R Treatment of iodine deficiency breast syndrome
US5250304A (en) * 1985-07-31 1993-10-05 Ghent William R Treatment of iodine deficiency diseases
US5171582A (en) * 1985-07-31 1992-12-15 Ghent William R Treatment of iodine deficiency diseases
US5589198A (en) * 1985-07-31 1996-12-31 943038 Ontario, Inc. Treatment of iodine deficiency diseases
US4849237A (en) * 1987-10-30 1989-07-18 Hurst William D Method for sanitizing poultry carcasses in a poultry processing plant utilizing ozonated water
US5629024A (en) * 1994-08-22 1997-05-13 Symbollon Corporation Method of forming an iodine based germicide composition

Also Published As

Publication number Publication date
EP1024815A1 (en) 2000-08-09
ES2191973T3 (es) 2003-09-16
DE69811105D1 (de) 2003-03-06
JP2003510243A (ja) 2003-03-18
JP4187410B2 (ja) 2008-11-26
CN1272789A (zh) 2000-11-08
WO1999021567A1 (en) 1999-05-06
NO20001673L (no) 2000-05-24
CN1150904C (zh) 2004-05-26
CA2301503C (en) 2005-01-04
IL134778A0 (en) 2001-04-30
AU1122799A (en) 1999-05-17
DK1024815T3 (da) 2003-05-19
EP1024815B1 (en) 2003-01-29
PT1024815E (pt) 2003-06-30
NO20001673D0 (no) 2000-03-31
RU2213564C2 (ru) 2003-10-10
AU750627B2 (en) 2002-07-25
KR100412219B1 (ko) 2003-12-24
US5885592A (en) 1999-03-23
CA2301503A1 (en) 1999-05-06
KR20010030861A (ko) 2001-04-16
ATE231725T1 (de) 2003-02-15
BR9812588A (pt) 2000-07-25

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Legal Events

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