DE69738033T2 - Verwendung von 1,3-propanediol derivaten - Google Patents
Verwendung von 1,3-propanediol derivaten Download PDFInfo
- Publication number
- DE69738033T2 DE69738033T2 DE69738033T DE69738033T DE69738033T2 DE 69738033 T2 DE69738033 T2 DE 69738033T2 DE 69738033 T DE69738033 T DE 69738033T DE 69738033 T DE69738033 T DE 69738033T DE 69738033 T2 DE69738033 T2 DE 69738033T2
- Authority
- DE
- Germany
- Prior art keywords
- compound
- graft
- rejection
- salt form
- propanediol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/131—Amines acyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/133—Amines having hydroxy groups, e.g. sphingosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Oncology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Light Receiving Elements (AREA)
- Peptides Or Proteins (AREA)
- Polyurethanes Or Polyureas (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9624038.7A GB9624038D0 (en) | 1996-11-19 | 1996-11-19 | Organic compounds |
| GB9624038 | 1996-11-19 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69738033D1 DE69738033D1 (de) | 2007-09-27 |
| DE69738033T2 true DE69738033T2 (de) | 2008-04-30 |
Family
ID=10803173
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69738033T Expired - Fee Related DE69738033T2 (de) | 1996-11-19 | 1997-11-17 | Verwendung von 1,3-propanediol derivaten |
| DE69730727T Expired - Fee Related DE69730727T2 (de) | 1996-11-19 | 1997-11-17 | Neue verwendung von 1,3-propanediol derivaten |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69730727T Expired - Fee Related DE69730727T2 (de) | 1996-11-19 | 1997-11-17 | Neue verwendung von 1,3-propanediol derivaten |
Country Status (24)
| Country | Link |
|---|---|
| US (3) | US6274629B1 (https=) |
| EP (2) | EP0941082B1 (https=) |
| JP (2) | JP4004070B2 (https=) |
| CN (2) | CN1293876C (https=) |
| AT (2) | ATE369846T1 (https=) |
| AU (1) | AU728420B2 (https=) |
| BR (1) | BR9713105A (https=) |
| CA (1) | CA2270952C (https=) |
| CZ (1) | CZ174999A3 (https=) |
| DE (2) | DE69738033T2 (https=) |
| DK (1) | DK1312359T3 (https=) |
| ES (2) | ES2227726T3 (https=) |
| GB (1) | GB9624038D0 (https=) |
| HU (1) | HUP0000343A3 (https=) |
| ID (1) | ID21568A (https=) |
| IL (1) | IL129824A (https=) |
| NO (1) | NO992259L (https=) |
| NZ (1) | NZ335629A (https=) |
| PL (1) | PL190348B1 (https=) |
| PT (2) | PT1312359E (https=) |
| RU (1) | RU2217136C2 (https=) |
| SI (1) | SI1312359T1 (https=) |
| SK (1) | SK284806B6 (https=) |
| WO (1) | WO1998022100A2 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1457478B1 (en) | 1998-11-11 | 2017-07-19 | Novartis AG | Production of 2-amino-2-[2-(4-alkyl-phenyl)ethyl]propane-1,3-diols |
| CN1411373A (zh) * | 1999-12-16 | 2003-04-16 | 特瓦制药工业有限公司 | 制备来氟米特的新方法和新晶形的来氟米特 |
| WO2002018395A1 (en) | 2000-08-31 | 2002-03-07 | Merck & Co., Inc. | Phosphate derivatives as immunoregulatory agents |
| ES2267993T3 (es) * | 2001-02-22 | 2007-03-16 | Novartis Ag | Uso de agentes de migracion acelerada de linfocitos para la fabricacion de un medicamento para el tratamiento de la funcion retardada del injerto. |
| CN1507451A (zh) * | 2001-04-20 | 2004-06-23 | �±Ȱ·�ķ�ɷ�����˾ | 可用作前体药物的修饰环孢菌素及其应用 |
| ES2322442T3 (es) * | 2001-06-08 | 2009-06-22 | Novartis Ag | Tratamiento o profilaxis del rechazo de injertos de celulas productoras de insulina. |
| GB0117921D0 (en) * | 2001-07-23 | 2001-09-12 | Novartis Ag | Organic compounds |
| US7780993B2 (en) * | 2001-09-07 | 2010-08-24 | Yeda Research And Development Co. Ltd. | Therapeutic transplantation using developing, human or porcine, renal or hepatic, grafts |
| US20040136972A1 (en) * | 2001-09-07 | 2004-07-15 | Yeda Research And Development Co. Ltd. | Methods of treating disease by transplantation of developing allogeneic or xenogeneic organs or tissues |
| GB0125443D0 (en) | 2001-10-23 | 2001-12-12 | Novartis Ag | Organic Compounds |
| BR0306811A (pt) | 2002-01-11 | 2004-10-26 | Sankyo Co | Composto, éster farmacologicamente aceitável do mesmo, composição farmacêutica e métodos para prevenção ou tratamento de doenças autoimunes, da artrite reumatóide e da rejeição causada pelo transplante de vários órgãos em um mamìfero |
| GB0217777D0 (en) * | 2002-07-31 | 2002-09-11 | Novartis Ag | Organic compounds |
| IL165425A0 (en) * | 2004-11-28 | 2006-01-15 | Yeda Res & Dev | Methods of treating disease by transplantation of developing allogeneic or xenogeneic organs or tissues |
| CA2521325C (en) | 2003-04-08 | 2010-09-14 | Novartis Ag | Solid pharmaceutical compositions comprising a s1p receptor agonist and a sugar alcohol |
| EP1484057A1 (en) * | 2003-06-06 | 2004-12-08 | Aventis Pharma Deutschland GmbH | Use of 2-amino-1-3-propanediol derivatives for the manufacture of a medicament for the treatment of various types of pain |
| US7524887B2 (en) | 2003-06-06 | 2009-04-28 | Sanofi-Aventis Deutschland Gmbh | 2-amino-1,3-propanediol compounds for the treatment of acute pain |
| EP1643983B1 (en) * | 2003-06-24 | 2010-05-05 | The University of Connecticut | Methods of inhibiting vascular permeability and apoptosis |
| US7074659B2 (en) * | 2003-11-13 | 2006-07-11 | Volterra Semiconductor Corporation | Method of fabricating a lateral double-diffused MOSFET (LDMOS) transistor |
| JP2005272453A (ja) | 2004-02-24 | 2005-10-06 | Sankyo Co Ltd | アミノアルコール化合物 |
| MX2007001236A (es) * | 2004-07-30 | 2007-03-23 | Novartis Ag | Formulaciones de compuestos de 2-amino-1, 3-propanodiol. |
| KR101346527B1 (ko) * | 2005-12-15 | 2013-12-31 | 미쓰비시 타나베 파마 코퍼레이션 | 아민 화합물 및 그 의약 용도 |
| AR085749A1 (es) | 2011-04-01 | 2013-10-23 | Novartis Ag | Formulaciones |
| RU2496486C1 (ru) | 2012-07-11 | 2013-10-27 | Александр Васильевич Иващенко | Фармацевтическая композиция с улучшенной сыпучестью, лекарственное средство, способ получения и применение |
| US9815772B2 (en) * | 2013-03-05 | 2017-11-14 | Biocon Limited | Process for the preparation of 2-amino-1,3-propane diol compounds and salts thereof |
| US20180250235A1 (en) | 2015-09-18 | 2018-09-06 | Sanovel Ilac Sanayi Ve Ticaret A.S. | Fingolimod capsule composition |
| JP2024521882A (ja) * | 2021-05-31 | 2024-06-04 | 上海雲晟研新生物科技有限公司 | フィンゴリモド薬用塩、製造方法、それを含む医薬組成物及び使用 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3904679A (en) * | 1972-05-23 | 1975-09-09 | Upjohn Co | 15-Methyl and 15-ethyl prostaglandin F{HD 2{331 {0 {B analogs |
| US6136310A (en) * | 1991-07-25 | 2000-10-24 | Idec Pharmaceuticals Corporation | Recombinant anti-CD4 antibodies for human therapy |
| CA2114015C (en) * | 1991-07-25 | 2002-12-10 | Roland A. Newman | Recombinant antibodies for human therapy |
| US5747034A (en) * | 1992-07-09 | 1998-05-05 | Chiron Corporation | Methods and materials for the induction of T cell anergy |
| GB9221220D0 (en) * | 1992-10-09 | 1992-11-25 | Sandoz Ag | Organic componds |
| US5604229A (en) * | 1992-10-21 | 1997-02-18 | Yoshitomi Pharmaceutical Industries, Ltd. | 2-amino-1,3-propanediol compound and immunosuppressant |
| ES2230571T3 (es) | 1995-12-28 | 2005-05-01 | Mitsubishi Pharma Corporation | `composicion farmaceutica destinada para la administracion topica que comprende el 2-amino-2-(2-(4-octilfenil)etil) propan-1,3-diol para el tratamiento de las enfermedades causadas por una alteracion inmunitaria. |
| JP2002241272A (ja) * | 1996-07-18 | 2002-08-28 | Mitsubishi Pharma Corp | 医薬処方組成物 |
| US6476004B1 (en) * | 1996-07-18 | 2002-11-05 | Mitsubishi Pharma Corporation | Pharmaceutical composition |
| DE69840169D1 (de) * | 1997-02-27 | 2008-12-11 | Novartis Ag | Arzneimittel zubereitung enthaltend 2-amino-2-ä2-(4-octylphenyl)ethylüpropane-1,3-diol, ein lecithin und ein saccharid |
-
1996
- 1996-11-19 GB GBGB9624038.7A patent/GB9624038D0/en active Pending
-
1997
- 1997-11-17 CA CA002270952A patent/CA2270952C/en not_active Expired - Fee Related
- 1997-11-17 SK SK659-99A patent/SK284806B6/sk unknown
- 1997-11-17 PL PL97333463A patent/PL190348B1/pl not_active IP Right Cessation
- 1997-11-17 BR BR9713105-9A patent/BR9713105A/pt not_active Application Discontinuation
- 1997-11-17 ID IDW990370A patent/ID21568A/id unknown
- 1997-11-17 EP EP97951219A patent/EP0941082B1/en not_active Expired - Lifetime
- 1997-11-17 RU RU99112577/14A patent/RU2217136C2/ru not_active IP Right Cessation
- 1997-11-17 CN CNB2004100059961A patent/CN1293876C/zh not_active Expired - Fee Related
- 1997-11-17 DK DK02025422T patent/DK1312359T3/da active
- 1997-11-17 AT AT02025422T patent/ATE369846T1/de not_active IP Right Cessation
- 1997-11-17 SI SI9730772T patent/SI1312359T1/sl unknown
- 1997-11-17 US US09/308,098 patent/US6274629B1/en not_active Expired - Lifetime
- 1997-11-17 AU AU54831/98A patent/AU728420B2/en not_active Ceased
- 1997-11-17 ES ES97951219T patent/ES2227726T3/es not_active Expired - Lifetime
- 1997-11-17 HU HU0000343A patent/HUP0000343A3/hu unknown
- 1997-11-17 WO PCT/EP1997/006408 patent/WO1998022100A2/en not_active Ceased
- 1997-11-17 CZ CZ991749A patent/CZ174999A3/cs unknown
- 1997-11-17 JP JP52320098A patent/JP4004070B2/ja not_active Expired - Fee Related
- 1997-11-17 EP EP02025422A patent/EP1312359B1/en not_active Expired - Lifetime
- 1997-11-17 DE DE69738033T patent/DE69738033T2/de not_active Expired - Fee Related
- 1997-11-17 ES ES02025422T patent/ES2289041T3/es not_active Expired - Lifetime
- 1997-11-17 DE DE69730727T patent/DE69730727T2/de not_active Expired - Fee Related
- 1997-11-17 IL IL12982497A patent/IL129824A/xx not_active IP Right Cessation
- 1997-11-17 PT PT02025422T patent/PT1312359E/pt unknown
- 1997-11-17 NZ NZ335629A patent/NZ335629A/en unknown
- 1997-11-17 PT PT97951219T patent/PT941082E/pt unknown
- 1997-11-17 AT AT97951219T patent/ATE275947T1/de not_active IP Right Cessation
- 1997-11-17 CN CNB971998582A patent/CN1146411C/zh not_active Expired - Fee Related
-
1999
- 1999-05-10 NO NO992259A patent/NO992259L/no unknown
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2001
- 2001-07-03 US US09/898,143 patent/US6486209B2/en not_active Expired - Fee Related
-
2002
- 2002-09-30 US US10/261,536 patent/US20030069315A1/en not_active Abandoned
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2004
- 2004-05-21 JP JP2004152002A patent/JP2004256554A/ja active Pending
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