IL129824A - Pharmaceutical compositions comprising 2-amino-1,3-propanediol derivatives for preventing and/or treating chronic rejection in a recipient for organ or tissue allo- or xenotransplants - Google Patents

Pharmaceutical compositions comprising 2-amino-1,3-propanediol derivatives for preventing and/or treating chronic rejection in a recipient for organ or tissue allo- or xenotransplants

Info

Publication number
IL129824A
IL129824A IL12982497A IL12982497A IL129824A IL 129824 A IL129824 A IL 129824A IL 12982497 A IL12982497 A IL 12982497A IL 12982497 A IL12982497 A IL 12982497A IL 129824 A IL129824 A IL 129824A
Authority
IL
Israel
Prior art keywords
xenotransplants
recipient
organ
amino
preventing
Prior art date
Application number
IL12982497A
Other languages
English (en)
Other versions
IL129824A0 (en
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Priority to IL14709997A priority Critical patent/IL147099A0/xx
Publication of IL129824A0 publication Critical patent/IL129824A0/xx
Publication of IL129824A publication Critical patent/IL129824A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/131—Amines acyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/133—Amines having hydroxy groups, e.g. sphingosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Transplantation (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Light Receiving Elements (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IL12982497A 1996-11-19 1997-11-17 Pharmaceutical compositions comprising 2-amino-1,3-propanediol derivatives for preventing and/or treating chronic rejection in a recipient for organ or tissue allo- or xenotransplants IL129824A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL14709997A IL147099A0 (en) 1996-11-19 1997-11-17 New use for 1,3-propanediol derivatives

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9624038.7A GB9624038D0 (en) 1996-11-19 1996-11-19 Organic compounds
PCT/EP1997/006408 WO1998022100A2 (en) 1996-11-19 1997-11-17 New use for 1,3-propanediol derivatives

Publications (2)

Publication Number Publication Date
IL129824A0 IL129824A0 (en) 2000-02-29
IL129824A true IL129824A (en) 2003-07-31

Family

ID=10803173

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12982497A IL129824A (en) 1996-11-19 1997-11-17 Pharmaceutical compositions comprising 2-amino-1,3-propanediol derivatives for preventing and/or treating chronic rejection in a recipient for organ or tissue allo- or xenotransplants

Country Status (24)

Country Link
US (3) US6274629B1 (https=)
EP (2) EP0941082B1 (https=)
JP (2) JP4004070B2 (https=)
CN (2) CN1146411C (https=)
AT (2) ATE275947T1 (https=)
AU (1) AU728420B2 (https=)
BR (1) BR9713105A (https=)
CA (1) CA2270952C (https=)
CZ (1) CZ174999A3 (https=)
DE (2) DE69730727T2 (https=)
DK (1) DK1312359T3 (https=)
ES (2) ES2227726T3 (https=)
GB (1) GB9624038D0 (https=)
HU (1) HUP0000343A3 (https=)
ID (1) ID21568A (https=)
IL (1) IL129824A (https=)
NO (1) NO992259D0 (https=)
NZ (1) NZ335629A (https=)
PL (1) PL190348B1 (https=)
PT (2) PT941082E (https=)
RU (1) RU2217136C2 (https=)
SI (1) SI1312359T1 (https=)
SK (1) SK284806B6 (https=)
WO (1) WO1998022100A2 (https=)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1129066T3 (da) 1998-11-11 2005-03-29 Novartis Ag Fremstilling af 2-amino-2-[2-(C2-20alkylphenyl)ethyl]propan-1,3-dioler
CN1411373A (zh) * 1999-12-16 2003-04-16 特瓦制药工业有限公司 制备来氟米特的新方法和新晶形的来氟米特
EP1315735A4 (en) 2000-08-31 2005-04-06 Merck & Co Inc Phosphate derivatives as immunoregulatory compounds
JP4318921B2 (ja) * 2001-02-22 2009-08-26 ノバルティス アクチエンゲゼルシャフト 移植片の機能発現遅延の処置のための医薬の製造のためのリンパ球ホーミング促進剤の使用
US6995139B2 (en) * 2001-04-20 2006-02-07 Debiopharm S.A. Cyclic undecapeptide pro-drugs and uses thereof
BR0209319A (pt) * 2001-06-08 2004-07-20 Novartis Ag Tratamento ou profilaxia de rejeição de enxerto de célula produtora de insulina
GB0117921D0 (en) * 2001-07-23 2001-09-12 Novartis Ag Organic compounds
US20040136972A1 (en) * 2001-09-07 2004-07-15 Yeda Research And Development Co. Ltd. Methods of treating disease by transplantation of developing allogeneic or xenogeneic organs or tissues
US7780993B2 (en) * 2001-09-07 2010-08-24 Yeda Research And Development Co. Ltd. Therapeutic transplantation using developing, human or porcine, renal or hepatic, grafts
GB0125443D0 (en) * 2001-10-23 2001-12-12 Novartis Ag Organic Compounds
DK1471054T3 (da) 2002-01-11 2009-11-09 Daiichi Sankyo Co Ltd Aminoalkohol-derivat eller phosphonsyre-derivat og medicinsk sammensætning, der indeholder disse
GB0217777D0 (en) * 2002-07-31 2002-09-11 Novartis Ag Organic compounds
IL165425A0 (en) * 2004-11-28 2006-01-15 Yeda Res & Dev Methods of treating disease by transplantation of developing allogeneic or xenogeneic organs or tissues
PE20130200A1 (es) 2003-04-08 2013-03-09 Novartis Ag Composicion farmaceutica que contiene un agonista del receptor s1p y un alcohol de azucar
US7524887B2 (en) 2003-06-06 2009-04-28 Sanofi-Aventis Deutschland Gmbh 2-amino-1,3-propanediol compounds for the treatment of acute pain
EP1484057A1 (en) * 2003-06-06 2004-12-08 Aventis Pharma Deutschland GmbH Use of 2-amino-1-3-propanediol derivatives for the manufacture of a medicament for the treatment of various types of pain
PL1643983T3 (pl) * 2003-06-24 2010-10-29 Univ Connecticut Sposoby hamowania przepuszczalności naczyń krwionośnych i apoptozy
US7074659B2 (en) * 2003-11-13 2006-07-11 Volterra Semiconductor Corporation Method of fabricating a lateral double-diffused MOSFET (LDMOS) transistor
NZ549162A (en) 2004-02-24 2009-12-24 Sankyo Co Amino-pyrrol alcohol compounds
PL1773307T3 (pl) * 2004-07-30 2015-03-31 Novartis Ag Preparaty 2-amino-1,3-propanodioli i ich analogów
BRPI0619894B8 (pt) * 2005-12-15 2021-05-25 Mitsubishi Tanabe Pharma Corp composto de amina e composição farmacêutica
AR085749A1 (es) 2011-04-01 2013-10-23 Novartis Ag Formulaciones
RU2496486C1 (ru) 2012-07-11 2013-10-27 Александр Васильевич Иващенко Фармацевтическая композиция с улучшенной сыпучестью, лекарственное средство, способ получения и применение
US9815772B2 (en) * 2013-03-05 2017-11-14 Biocon Limited Process for the preparation of 2-amino-1,3-propane diol compounds and salts thereof
US20180250235A1 (en) 2015-09-18 2018-09-06 Sanovel Ilac Sanayi Ve Ticaret A.S. Fingolimod capsule composition
CN115477590B (zh) * 2021-05-31 2023-12-12 上海云晟研新生物科技有限公司 芬戈莫德药用盐、制备方法、含其的药物组合物及应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3904679A (en) * 1972-05-23 1975-09-09 Upjohn Co 15-Methyl and 15-ethyl prostaglandin F{HD 2{331 {0 {B analogs
ES2196002T3 (es) * 1991-07-25 2003-12-16 Idec Pharma Corp Anticuerpos recombinantes para terapia humana.
US6136310A (en) * 1991-07-25 2000-10-24 Idec Pharmaceuticals Corporation Recombinant anti-CD4 antibodies for human therapy
US5747034A (en) * 1992-07-09 1998-05-05 Chiron Corporation Methods and materials for the induction of T cell anergy
GB9221220D0 (en) * 1992-10-09 1992-11-25 Sandoz Ag Organic componds
DE69321823T2 (de) * 1992-10-21 1999-06-02 Taito Co., Ltd., Tokio/Tokyo 2-amino-1, 3- propandiolverbindung und immunosuppressium
WO1997024112A1 (en) * 1995-12-28 1997-07-10 Yoshitomi Pharmaceutical Industries, Ltd. External preparation
JP2002241272A (ja) * 1996-07-18 2002-08-28 Mitsubishi Pharma Corp 医薬処方組成物
US6476004B1 (en) * 1996-07-18 2002-11-05 Mitsubishi Pharma Corporation Pharmaceutical composition
KR20000075745A (ko) * 1997-02-27 2000-12-26 가마후라 아키오 의약 조성물

Also Published As

Publication number Publication date
ES2227726T3 (es) 2005-04-01
US20030069315A1 (en) 2003-04-10
EP1312359A3 (en) 2004-01-02
PL333463A1 (en) 1999-12-20
DE69738033T2 (de) 2008-04-30
SK65999A3 (en) 1999-12-10
SI1312359T1 (sl) 2008-08-31
CN1237906A (zh) 1999-12-08
HUP0000343A3 (en) 2001-06-28
PT1312359E (pt) 2007-11-09
RU2217136C2 (ru) 2003-11-27
GB9624038D0 (en) 1997-01-08
EP1312359B1 (en) 2007-08-15
ES2289041T3 (es) 2008-02-01
CN1293876C (zh) 2007-01-10
AU5483198A (en) 1998-06-10
ATE369846T1 (de) 2007-09-15
DK1312359T3 (da) 2007-10-08
JP2001503780A (ja) 2001-03-21
WO1998022100A2 (en) 1998-05-28
BR9713105A (pt) 2000-04-11
EP1312359A2 (en) 2003-05-21
HUP0000343A2 (hu) 2000-12-28
ID21568A (id) 1999-06-24
HK1022639A1 (en) 2000-08-18
PT941082E (pt) 2004-12-31
US6274629B1 (en) 2001-08-14
WO1998022100A3 (en) 1998-06-25
JP4004070B2 (ja) 2007-11-07
SK284806B6 (sk) 2005-11-03
JP2004256554A (ja) 2004-09-16
DE69730727D1 (de) 2004-10-21
CA2270952C (en) 2007-09-18
NO992259L (no) 1999-05-10
CZ174999A3 (cs) 1999-08-11
ATE275947T1 (de) 2004-10-15
CA2270952A1 (en) 1998-05-28
EP0941082B1 (en) 2004-09-15
DE69738033D1 (de) 2007-09-27
DE69730727T2 (de) 2005-09-22
NO992259D0 (no) 1999-05-10
EP0941082A2 (en) 1999-09-15
PL190348B1 (pl) 2005-11-30
IL129824A0 (en) 2000-02-29
CN1515253A (zh) 2004-07-28
US6486209B2 (en) 2002-11-26
AU728420B2 (en) 2001-01-11
US20010056124A1 (en) 2001-12-27
NZ335629A (en) 2001-09-28
CN1146411C (zh) 2004-04-21

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees