DE60000937T2 - Verwendung von 15-deoxyspergualin zur behandlung von hyperreaktiven entzündlichen erkrankungen und autoimmunerkrankungen - Google Patents

Verwendung von 15-deoxyspergualin zur behandlung von hyperreaktiven entzündlichen erkrankungen und autoimmunerkrankungen

Info

Publication number
DE60000937T2
DE60000937T2 DE60000937T DE60000937T DE60000937T2 DE 60000937 T2 DE60000937 T2 DE 60000937T2 DE 60000937 T DE60000937 T DE 60000937T DE 60000937 T DE60000937 T DE 60000937T DE 60000937 T2 DE60000937 T2 DE 60000937T2
Authority
DE
Germany
Prior art keywords
diseases
hyperreactive
deoxyspergualin
flammable
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60000937T
Other languages
English (en)
Other versions
DE60000937D1 (de
Inventor
Rainer Birck
Johannes Drexler
Osamu Hotta
Rainer Nowack
Der Woude Johannes Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Euro Nippon Kayaku GmbH
Nippon Kayaku Co Ltd
Original Assignee
Euro Nippon Kayaku GmbH
Nippon Kayaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Nippon Kayaku GmbH, Nippon Kayaku Co Ltd filed Critical Euro Nippon Kayaku GmbH
Priority to DE60000937T priority Critical patent/DE60000937T2/de
Application granted granted Critical
Publication of DE60000937D1 publication Critical patent/DE60000937D1/de
Publication of DE60000937T2 publication Critical patent/DE60000937T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE60000937T 1999-05-25 2000-04-14 Verwendung von 15-deoxyspergualin zur behandlung von hyperreaktiven entzündlichen erkrankungen und autoimmunerkrankungen Expired - Lifetime DE60000937T2 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE60000937T DE60000937T2 (de) 1999-05-25 2000-04-14 Verwendung von 15-deoxyspergualin zur behandlung von hyperreaktiven entzündlichen erkrankungen und autoimmunerkrankungen

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19923961A DE19923961A1 (de) 1999-05-25 1999-05-25 Verwendung von 15-Deoxyspergualin zur Behandlung von hyperreaktiven entzündlichen Erkrankungen und Autoimmunerkrankungen
DE60000937T DE60000937T2 (de) 1999-05-25 2000-04-14 Verwendung von 15-deoxyspergualin zur behandlung von hyperreaktiven entzündlichen erkrankungen und autoimmunerkrankungen
PCT/EP2000/003430 WO2000071103A2 (en) 1999-05-25 2000-04-14 Use of 15-deoxyspergualin for the treatment of hyperreactive inflammatory diseases and autoimmune diseases

Publications (2)

Publication Number Publication Date
DE60000937D1 DE60000937D1 (de) 2003-01-16
DE60000937T2 true DE60000937T2 (de) 2003-09-04

Family

ID=7909146

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19923961A Withdrawn DE19923961A1 (de) 1999-05-25 1999-05-25 Verwendung von 15-Deoxyspergualin zur Behandlung von hyperreaktiven entzündlichen Erkrankungen und Autoimmunerkrankungen
DE60000937T Expired - Lifetime DE60000937T2 (de) 1999-05-25 2000-04-14 Verwendung von 15-deoxyspergualin zur behandlung von hyperreaktiven entzündlichen erkrankungen und autoimmunerkrankungen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE19923961A Withdrawn DE19923961A1 (de) 1999-05-25 1999-05-25 Verwendung von 15-Deoxyspergualin zur Behandlung von hyperreaktiven entzündlichen Erkrankungen und Autoimmunerkrankungen

Country Status (20)

Country Link
US (2) US7153887B1 (de)
EP (1) EP1180026B1 (de)
JP (2) JP4422349B2 (de)
KR (1) KR100681626B1 (de)
CN (1) CN1199636C (de)
AR (1) AR024071A1 (de)
AT (1) ATE228833T1 (de)
AU (1) AU762018B2 (de)
BR (1) BR0008637A (de)
CA (1) CA2362582C (de)
CZ (1) CZ299440B6 (de)
DE (2) DE19923961A1 (de)
ES (1) ES2188538T3 (de)
HU (1) HU228843B1 (de)
MX (1) MXPA01008587A (de)
PL (1) PL352314A1 (de)
RU (1) RU2255732C2 (de)
TW (1) TWI283175B (de)
WO (1) WO2000071103A2 (de)
ZA (1) ZA200106596B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2542840A1 (en) * 2003-10-22 2005-05-12 University Of Rochester Anti-thymocyte antiserum and use thereof to trigger b cell apoptosis
AR048210A1 (es) * 2003-12-19 2006-04-12 Chugai Pharmaceutical Co Ltd Un agente preventivo para la vasculitis.
PT2012814E (pt) * 2006-04-12 2013-07-18 Genzyme Corp Métodos de tratamento de doenças auto-imunes

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6083503A (en) * 1991-08-28 2000-07-04 The United States Of America As Represented By The Department Of Health And Human Services Interleukin-2 stimulated T lymphocyte cell death for the treatment of autoimmune diseases, allergic responses, and graft rejection
FR2698628B1 (fr) * 1992-12-02 1995-02-17 Fournier Ind & Sante Analogues de 15-déoxyspergualine, leur procédé de préparation et leur utilisation en thérapeutique.
US5250442A (en) * 1993-04-08 1993-10-05 Orestes Cabezas Method of treating rheumatoid arthritis using tetracycline
FR2716452B1 (fr) * 1994-02-24 1996-05-10 Fournier Ind & Sante Analogues de la 15-déoxyspergualine, leur procédé de préparation et leur utilisation en thérapeutique.
US5505715A (en) * 1994-02-25 1996-04-09 Bristol-Myers Squibb Company Iontophoretic transdermal delivery of deoxyspergualin compounds
ES2124926T3 (es) * 1994-03-22 1999-02-16 Nippon Kayaku Kk Uso de desoxipergualina para la preparacion de un medicamento para el tratamiento de enfermedades inflamatorias e hiperreactivas.
US5624938A (en) * 1994-07-18 1997-04-29 The Trustees Of Columbia University In The City Of New York Use of chloroquine to treat multiple sclerosis
FR2734263B1 (fr) * 1995-05-17 1997-06-20 Fournier Ind & Sante Analogues de la 15-deoxyspergualine, leur procede de preparation et leur utilisation en therapeutique
US5679651A (en) * 1995-06-05 1997-10-21 Richardson; Bruce C. Treatment for systemic lupus erythematosus
DE19711803A1 (de) * 1997-03-21 1998-09-24 Hoechst Ag Verlängerung der Expression von transgenen Proteinen durch immunmodulierende Behandlung mit 15-Deoxyspergualin
DE19728436A1 (de) * 1997-07-03 1999-01-07 Niels Franke Niedrigdosierte 15-Desoxyspergualin-Präparate
TW536400B (en) * 1997-07-18 2003-06-11 Nippon Kayaku Kk Pharmaceutical composition for the treatment of immunodeficiency disease which cause by HIV infection

Also Published As

Publication number Publication date
US7153887B1 (en) 2006-12-26
JP4422349B2 (ja) 2010-02-24
JP2009263397A (ja) 2009-11-12
ATE228833T1 (de) 2002-12-15
WO2000071103A3 (en) 2001-06-21
HUP0200354A2 (hu) 2002-05-29
CA2362582C (en) 2008-10-07
MXPA01008587A (es) 2003-06-24
BR0008637A (pt) 2002-01-08
EP1180026A2 (de) 2002-02-20
KR100681626B1 (ko) 2007-02-09
CA2362582A1 (en) 2000-11-30
CZ20014158A3 (cs) 2002-06-12
CZ299440B6 (cs) 2008-07-30
HU228843B1 (en) 2013-06-28
AR024071A1 (es) 2002-09-04
DE19923961A1 (de) 2000-11-30
US20060293391A1 (en) 2006-12-28
US7776829B2 (en) 2010-08-17
AU762018B2 (en) 2003-06-19
HUP0200354A3 (en) 2003-03-28
EP1180026B1 (de) 2002-12-04
JP2003500351A (ja) 2003-01-07
WO2000071103A2 (en) 2000-11-30
CN1351490A (zh) 2002-05-29
ZA200106596B (en) 2002-08-12
KR20020010126A (ko) 2002-02-02
AU4550400A (en) 2000-12-12
PL352314A1 (en) 2003-08-11
ES2188538T3 (es) 2003-07-01
RU2255732C2 (ru) 2005-07-10
TWI283175B (en) 2007-07-01
CN1199636C (zh) 2005-05-04
DE60000937D1 (de) 2003-01-16

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