DE69840169D1 - Arzneimittel zubereitung enthaltend 2-amino-2-ä2-(4-octylphenyl)ethylüpropane-1,3-diol, ein lecithin und ein saccharid - Google Patents

Arzneimittel zubereitung enthaltend 2-amino-2-ä2-(4-octylphenyl)ethylüpropane-1,3-diol, ein lecithin und ein saccharid

Info

Publication number
DE69840169D1
DE69840169D1 DE69840169T DE69840169T DE69840169D1 DE 69840169 D1 DE69840169 D1 DE 69840169D1 DE 69840169 T DE69840169 T DE 69840169T DE 69840169 T DE69840169 T DE 69840169T DE 69840169 D1 DE69840169 D1 DE 69840169D1
Authority
DE
Germany
Prior art keywords
octylphenyl
saccharide
lecithin
diol
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69840169T
Other languages
English (en)
Inventor
Atsushi Sakai
Rumiko Masuda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Application granted granted Critical
Publication of DE69840169D1 publication Critical patent/DE69840169D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
DE69840169T 1997-02-27 1998-02-25 Arzneimittel zubereitung enthaltend 2-amino-2-ä2-(4-octylphenyl)ethylüpropane-1,3-diol, ein lecithin und ein saccharid Expired - Lifetime DE69840169D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4366897 1997-02-27
PCT/JP1998/000755 WO1998037875A1 (fr) 1997-02-27 1998-02-25 Composition medicamenteuse

Publications (1)

Publication Number Publication Date
DE69840169D1 true DE69840169D1 (de) 2008-12-11

Family

ID=12670236

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69840169T Expired - Lifetime DE69840169D1 (de) 1997-02-27 1998-02-25 Arzneimittel zubereitung enthaltend 2-amino-2-ä2-(4-octylphenyl)ethylüpropane-1,3-diol, ein lecithin und ein saccharid

Country Status (19)

Country Link
US (1) US6277888B1 (de)
EP (2) EP2030614A1 (de)
JP (1) JP4153563B2 (de)
KR (1) KR20000075745A (de)
CN (1) CN1178653C (de)
AT (1) ATE412407T1 (de)
AU (1) AU735406B2 (de)
BR (1) BR9811453A (de)
CA (1) CA2282378C (de)
DE (1) DE69840169D1 (de)
DK (1) DK0990440T3 (de)
ES (1) ES2317663T3 (de)
HK (2) HK1027039A1 (de)
IL (1) IL131608A (de)
NZ (1) NZ337823A (de)
PT (1) PT990440E (de)
RU (1) RU2188004C2 (de)
SI (1) SI0990440T1 (de)
WO (1) WO1998037875A1 (de)

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GB9624038D0 (en) * 1996-11-19 1997-01-08 Sandoz Ltd Organic compounds
JP4627356B2 (ja) * 1999-06-30 2011-02-09 松森  昭 ウイルス性心筋炎の予防または治療薬剤
AU8533101A (en) 2000-08-31 2002-03-13 Merck & Co Inc Phosphate derivatives as immunoregulatory agents
DK1471054T3 (da) 2002-01-11 2009-11-09 Daiichi Sankyo Co Ltd Aminoalkohol-derivat eller phosphonsyre-derivat og medicinsk sammensætning, der indeholder disse
PE20131352A1 (es) * 2003-04-08 2013-11-14 Novartis Ag Composicion farmaceutica que contiene un agonista del receptor s1p y un alcohol de azucar
GB0329498D0 (en) * 2003-12-19 2004-01-28 Novartis Ag Organic compounds
TWI355934B (en) 2004-02-24 2012-01-11 Sankyo Co Pharmaceutical composition for treatment or prophy
CA2574664C (en) * 2004-07-30 2013-01-15 Novartis Ag Compound formulations of 2-amino-1,3-propanediol compounds
KR20140095109A (ko) * 2004-11-29 2014-07-31 노파르티스 아게 S1p 수용체 효능제의 투여 용법
EP1679065A1 (de) 2005-01-07 2006-07-12 OctoPlus Sciences B.V. Zubereitung mit kontrollierter Freisetzung von Interferon auf PEGT/PBT-Block-Copolymer-Basis
PL1926483T3 (pl) * 2005-09-09 2011-05-31 Novartis Ag Leczenie chorób autoimmunologicznych
EP1923055A1 (de) * 2006-09-26 2008-05-21 Novartis AG Gefriergetrocknete pharmazeutische Zusammensetzung mit einem S1P Agonisten oder Modulator
AU2011235934A1 (en) * 2006-09-26 2011-11-03 Novartis Ag Pharmaceutical compositions comprising an S1P modulator
EP3733162A1 (de) 2007-10-12 2020-11-04 Novartis AG Zusammensetzung mit sphingosin-1-phosphat (s1p)-rezeptormodulatoren
CN104800208A (zh) 2008-03-17 2015-07-29 埃科特莱茵药品有限公司 选择性s1p1受体激动剂的给药方案
JO3177B1 (ar) 2011-04-01 2018-03-08 Novartis Ag تركيبات تتالف من 2-أمينو-2- [ 2- ( 4- أكتيل فينيل ) إثيل ] بروبان - 3, 1- ديول
RU2483748C2 (ru) * 2011-04-15 2013-06-10 Леонид Леонидович Клопотенко Фармацевтическая композиция, содержащая инсулин и липосомы, для местного применения в виде пластыря
RU2483749C2 (ru) * 2011-04-15 2013-06-10 Леонид Леонидович Клопотенко Фармацевтическая композиция, содержащая инсулин и липосомы, для местного применения в виде биопленки
MX364643B (es) * 2011-08-03 2019-05-03 Ma Zhongmin USO DEL COMPUESTO FTY720: 2-amino - 2-[2-(4-octilfenil) etil] propano-1,3-diol (fingolimod) EN EL TRATAMIENTO DE PACIENTES CON DIABETES DE TIPO 2.
JP6316422B2 (ja) * 2013-07-29 2018-04-25 アイザント ドラッグ リサーチ ソリューションズ プライベート リミテッドAizant Drug Research Solutions Pvt Ltd フィンゴリモドの医薬組成物
GR1009654B (el) 2018-08-31 2019-11-18 Φαρματεν Α.Β.Ε.Ε. Φαρμακευτικο σκευασμα που περιλαμβανει εναν ανοσοτροποποιητικο παραγοντα και μεθοδος για την παρασκευη αυτου

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JPS5612993B2 (de) 1973-09-03 1981-03-25
US4020159A (en) * 1974-10-08 1977-04-26 Apotheker A. Herbert K.G., Fabrik Pharmazeutischer Praparate Wiesbaden Methods of and medications for treating cardiac disorders by using strophanthin
JPS5562010A (en) * 1978-10-31 1980-05-10 Ajinomoto Co Inc Fat emulsion for intravenous injection
AU5078885A (en) * 1984-12-20 1986-06-26 Warner-Lambert Company Non-irritant detergent
JPS61172814A (ja) 1985-01-25 1986-08-04 Ss Pharmaceut Co Ltd 安定な低溶血性ビタミンe注射液
JPS63152327A (ja) 1987-11-20 1988-06-24 Toyama Chem Co Ltd 脂肪乳剤から成る溶血防止用組成物を含有する製剤
JPH01172814A (ja) 1987-12-26 1989-07-07 Canon Inc レーザーユニット
AU6461090A (en) 1989-10-30 1991-05-02 Abbott Laboratories Injectable formulation for lipophilic drugs
US5091188A (en) * 1990-04-26 1992-02-25 Haynes Duncan H Phospholipid-coated microcrystals: injectable formulations of water-insoluble drugs
JPH04173736A (ja) 1990-11-06 1992-06-22 Nippon Shinyaku Co Ltd 乳化剤
WO1994008943A1 (en) * 1992-10-21 1994-04-28 Yoshitomi Pharmaceutical Industries, Ltd. 2-amino-1,3-propanediol compound and immunosuppressant
JPH06340525A (ja) 1993-06-02 1994-12-13 Lion Corp 安定な低眼刺激性ビタミンa類可溶化点眼剤
EP0778263B1 (de) 1994-08-22 2002-01-09 Welfide Corporation Benzolderivate und deren medizinische verwendung
JP3169807B2 (ja) 1995-09-18 2001-05-28 本田技研工業株式会社 ロータ組み付け装置
IL121625A (en) * 1995-12-28 2001-09-13 Welfide Corp Preparation containing 2 - amino - 2 - (-2 (-4-octylphenyl) ethyl) propane - 1, 3, - dial for local topical use
JP2002241272A (ja) * 1996-07-18 2002-08-28 Mitsubishi Pharma Corp 医薬処方組成物
KR100190826B1 (ko) * 1996-08-26 1999-06-01 강재헌 적혈구 용혈 억제용 약제학적 조성물 및 그의제조방법

Also Published As

Publication number Publication date
CA2282378A1 (en) 1998-09-03
AU735406B2 (en) 2001-07-05
HK1027039A1 (en) 2001-01-05
PT990440E (pt) 2009-02-05
EP0990440B1 (de) 2008-10-29
JP4153563B2 (ja) 2008-09-24
AU6115598A (en) 1998-09-18
CA2282378C (en) 2008-12-30
HK1027959A1 (en) 2001-02-02
IL131608A0 (en) 2001-01-28
SI0990440T1 (sl) 2009-04-30
NZ337823A (en) 2001-04-27
CN1178653C (zh) 2004-12-08
RU2188004C2 (ru) 2002-08-27
EP2030614A1 (de) 2009-03-04
US6277888B1 (en) 2001-08-21
DK0990440T3 (da) 2009-02-23
BR9811453A (pt) 2000-09-12
IL131608A (en) 2003-02-12
EP0990440A4 (de) 2004-04-21
EP0990440A1 (de) 2000-04-05
CN1253499A (zh) 2000-05-17
ES2317663T3 (es) 2009-04-16
WO1998037875A1 (fr) 1998-09-03
KR20000075745A (ko) 2000-12-26
ATE412407T1 (de) 2008-11-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336

8328 Change in the person/name/address of the agent

Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN