DE69731309D1 - Impfstofformel auf polynukleotidbasis zur behandlung von hundekrankheiten, insbesondere solcher des atmungs- und verdauungstraktes - Google Patents

Impfstofformel auf polynukleotidbasis zur behandlung von hundekrankheiten, insbesondere solcher des atmungs- und verdauungstraktes

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Publication number
DE69731309D1
DE69731309D1 DE69731309T DE69731309T DE69731309D1 DE 69731309 D1 DE69731309 D1 DE 69731309D1 DE 69731309 T DE69731309 T DE 69731309T DE 69731309 T DE69731309 T DE 69731309T DE 69731309 D1 DE69731309 D1 DE 69731309D1
Authority
DE
Germany
Prior art keywords
polynucleotide
respiratory
treatment
especially those
digestive tract
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69731309T
Other languages
English (en)
Other versions
DE69731309T3 (de
DE69731309T2 (de
Inventor
Jean-Christophe Audonnet
Annabelle Bouchardon
Michel Riviere
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Animal Health France SAS
Original Assignee
Merial SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9494495&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69731309(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merial SAS filed Critical Merial SAS
Publication of DE69731309D1 publication Critical patent/DE69731309D1/de
Application granted granted Critical
Publication of DE69731309T2 publication Critical patent/DE69731309T2/de
Publication of DE69731309T3 publication Critical patent/DE69731309T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/0225—Spirochetes, e.g. Treponema, Leptospira, Borrelia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
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    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
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    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18411—Morbillivirus, e.g. Measles virus, canine distemper
    • C12N2760/18434—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20111—Lyssavirus, e.g. rabies virus
    • C12N2760/20122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20111—Lyssavirus, e.g. rabies virus
    • C12N2760/20134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
    • C12N2770/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
DE69731309.3T 1996-07-19 1997-07-15 Impfstofformel auf polynukleotidbasis zur behandlung von hundekrankheiten, insbesondere solcher des atmungs- und verdauungstraktes Expired - Lifetime DE69731309T3 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR9609401A FR2751227B1 (fr) 1996-07-19 1996-07-19 Formule de vaccin polynucleotidique contre les pathologies canines, notamment les pathologies respiratoires et digestives
FR9609401 1996-07-19
EP97933747.4A EP0954332B2 (de) 1996-07-19 1997-07-15 Impfstofformel auf polynukleotidbasis zur behandlung von hundekrankheiten, insbesondere solcher des atmungs- und verdauungstraktes
PCT/FR1997/001316 WO1998003199A1 (fr) 1996-07-19 1997-07-15 Formule de vaccin polynucleotidique contre les pathologies canines, notamment les pathologies respiratoires et digestives

Publications (3)

Publication Number Publication Date
DE69731309D1 true DE69731309D1 (de) 2004-11-25
DE69731309T2 DE69731309T2 (de) 2005-11-17
DE69731309T3 DE69731309T3 (de) 2015-06-03

Family

ID=9494495

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69731309.3T Expired - Lifetime DE69731309T3 (de) 1996-07-19 1997-07-15 Impfstofformel auf polynukleotidbasis zur behandlung von hundekrankheiten, insbesondere solcher des atmungs- und verdauungstraktes

Country Status (17)

Country Link
US (2) US6228846B1 (de)
EP (1) EP0954332B2 (de)
JP (1) JP2000515521A (de)
KR (3) KR20000067866A (de)
AR (1) AR034997A1 (de)
AU (1) AU733563B2 (de)
BR (1) BR9710509A (de)
CA (1) CA2260273C (de)
CZ (1) CZ300385B6 (de)
DE (1) DE69731309T3 (de)
FR (1) FR2751227B1 (de)
NZ (1) NZ333780A (de)
PL (1) PL190150B1 (de)
RU (1) RU2319504C2 (de)
TW (1) TW587942B (de)
WO (1) WO1998003199A1 (de)
ZA (1) ZA976284B (de)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2751227B1 (fr) * 1996-07-19 1998-11-27 Rhone Merieux Formule de vaccin polynucleotidique contre les pathologies canines, notamment les pathologies respiratoires et digestives
US7294338B2 (en) * 1996-07-19 2007-11-13 Merial Polynucleotide vaccine formula against canine pathologies, in particular respiratory and digestive pathologies
CA2223029A1 (en) 1997-02-12 1998-08-12 Akzo Nobel Nv Canine parvovirus dna vaccines
EP0863151A1 (de) * 1997-02-12 1998-09-09 Akzo Nobel N.V. Hundeparvovirus DNA Impfstoffe
US6368603B1 (en) * 1997-03-05 2002-04-09 Merial Limited Lyme combination compositions and uses
NZ515993A (en) * 1999-06-10 2004-04-30 Merial Sas DNA vaccines for pets and sport animals
FR2794648B1 (fr) * 1999-06-10 2003-03-07 Merial Sas Vaccins adn pour animaux de compagnie et de sport
EP1365799B1 (de) * 2001-02-15 2005-09-07 The Registrar, Indian Institute of Science Neue vakzinformulierung aus dna-vakzine-inaktiviertem virus
FR2823222B1 (fr) 2001-04-06 2004-02-06 Merial Sas Vaccin contre le virus de la fievre du nil
US7906311B2 (en) 2002-03-20 2011-03-15 Merial Limited Cotton rat lung cells for virus culture
JP2006512368A (ja) * 2002-12-19 2006-04-13 アクゾ・ノベル・エヌ・ベー 乳汁を介して母親由来抗体を伝達する三価ワクチン
EP2390352A1 (de) 2003-03-18 2011-11-30 Quantum Genetics Ireland Limited Systeme und Methoden zur Erhöhung der Milchproduktion bei Tieren
US7468273B2 (en) 2003-05-01 2008-12-23 Meial Limited Canine GHRH gene, polypeptides and methods of use
EP1668112A4 (de) 2003-06-20 2009-04-29 Protein Sciences Corp Sars-immunogene exprimierende vektoren, solche vektoren oder expressionsprodukte davon enthaltende zusammensetzungen, verfahren und tests zur herstellung und verwendung
ES2417019T3 (es) 2003-11-13 2013-08-05 University Of Georgia Research Foundation, Inc. Procedimiento de caracterización del virus de la enfermedad de la bursitis infecciosa
WO2005112544A2 (en) 2004-02-19 2005-12-01 The Governors Of The University Of Alberta Leptin promoter polymorphisms and uses thereof
DE602006013117D1 (de) 2005-04-25 2010-05-06 Merial Ltd Nipah-virus-impfstoffe
US20080241184A1 (en) 2005-08-25 2008-10-02 Jules Maarten Minke Canine influenza vaccines
US7771995B2 (en) 2005-11-14 2010-08-10 Merial Limited Plasmid encoding human BMP-7
EP1951751B1 (de) 2005-11-14 2017-11-01 Merial, Inc. Gentherapie bei nierenversagen
US7767686B2 (en) * 2006-03-03 2010-08-03 Covidien Ag Method of using adenosine receptor blockers during tissue ablation
EP2759307B1 (de) 2006-03-29 2016-11-09 Merial Limited Impfstoff gegen Streptokokken
US7862821B2 (en) 2006-06-01 2011-01-04 Merial Limited Recombinant vaccine against bluetongue virus
US20080274137A1 (en) * 2007-05-02 2008-11-06 Jean Christophe Francis Audonnet DNA plasmids having improved expression and stability
UA100692C2 (ru) 2007-05-02 2013-01-25 Мериал Лимитед Днк-плазмиды, имеющие повышенную экспрессию и стабильность
MX2011005604A (es) 2008-11-28 2011-09-01 Merial Ltd Vacuna recombinante para influenza aviar y sus usos.
MX2011010406A (es) 2009-04-03 2012-01-20 Merial Ltd Vacunas aviares vectorizadas con el virus de la emfermedad de newcastle.
PE20121685A1 (es) 2009-12-28 2012-12-28 Merial Ltd Antigeno ndv recombinante y usos del mismo
US20130197612A1 (en) 2010-02-26 2013-08-01 Jack W. Lasersohn Electromagnetic Radiation Therapy
MA34087B1 (fr) 2010-03-12 2013-03-05 Merial Ltd Vaccins recombinants contre le virus de la langue bleue et leurs utilisations
EP3156070A3 (de) 2010-08-31 2017-06-14 Merial Inc. Auf das virus der newcastle-krankheit gerichtete herpesvirus-impfstoffe
WO2012090073A2 (en) 2010-12-30 2012-07-05 The Netherlands Cancer Institute Methods and compositions for predicting chemotherapy sensitivity
EP2694678A2 (de) 2011-04-04 2014-02-12 Netherland Cancer Institute Verfahren und zusammensetzungen zur vorhersage der resistenz gegenüber einer antikrebsbehandlung
US20140296248A1 (en) 2011-04-04 2014-10-02 Stichting het Nederlands Kanker Instiuut-Antoni van Leeuwenhoek ziekenhuis Methods and compositions for predicting resistance to anticancer treatment
WO2012145577A1 (en) 2011-04-20 2012-10-26 Merial Limited Adjuvanted rabies vaccine with improved viscosity profile
EP2701736A1 (de) 2011-04-25 2014-03-05 Advanced Bioscience Laboratories, Inc. Trunkierte hiv-hüllproteine (env), verfahren und zugehörige zusammensetzungen
NZ618125A (en) 2011-05-27 2016-03-31 Merial Ltd Genetic vaccines against hendra virus and nipah virus
ES2674439T3 (es) 2011-06-01 2018-06-29 Merial, Inc. Administración sin aguja de vacunas contra el VSRRP
LT2741740T (lt) 2011-08-12 2017-08-10 Merial, Inc. Biologinių produktų, ypatingai vakcinų, vakuuminis konservavimas
EP2586461A1 (de) 2011-10-27 2013-05-01 Christopher L. Parks Von einem eingehüllten Virus abgeleitete Virenpartikel
WO2013093629A2 (en) 2011-12-20 2013-06-27 Netherlands Cancer Institute Modular vaccines, methods and compositions related thereto
WO2013123242A1 (en) 2012-02-14 2013-08-22 Merial Limited Recombinant poxviral vectors expressing both rabies and ox40 proteins, and vaccines made therefrom
MX353786B (es) 2012-02-14 2018-01-29 Merial Inc Vacunas de subunidades de rotavirus, metodos de preparacion y uso de las mismas.
WO2013138776A1 (en) 2012-03-16 2013-09-19 Merial Limited Novel methods for providing long-term protective immunity against rabies in animals, based upon administration of replication-deficient flavivirus expressing rabies g
US9347065B2 (en) 2012-03-29 2016-05-24 International Aids Vaccine Initiative Methods to improve vector expression and genetic stability
ES2664069T3 (es) 2012-06-13 2018-04-18 Merial, Inc. Vacunas contra BTV y AHSV de genoma reordenado
US20140170180A1 (en) 2012-12-17 2014-06-19 Boehringer Ingelheim Vetmedica, Inc. Porcine parvovirus 5a, methods of use and vaccine
US20140234354A1 (en) 2013-02-15 2014-08-21 Boehringer Ingelheim Vetmedica, Inc. Porcine parvovirus 5b, methods of use and vaccine
US9556419B2 (en) 2013-03-12 2017-01-31 Merial Inc. Reverse genetics Schmallenberg virus vaccine compositions, and methods of use thereof
CA2915712A1 (en) * 2013-08-21 2015-02-26 Margit SCHNEE Rabies vaccine
US10801070B2 (en) 2013-11-25 2020-10-13 The Broad Institute, Inc. Compositions and methods for diagnosing, evaluating and treating cancer
WO2015085147A1 (en) 2013-12-05 2015-06-11 The Broad Institute Inc. Polymorphic gene typing and somatic change detection using sequencing data
WO2015095811A2 (en) 2013-12-20 2015-06-25 The Board Institute Inc. Combination therapy with neoantigen vaccine
AU2015343369B2 (en) 2014-11-03 2018-11-22 Georgia Tech Research Corporation Methods of using microneedle vaccine formulations to elicit in animals protective immunity against rabies virus
WO2016100977A1 (en) 2014-12-19 2016-06-23 The Broad Institute Inc. Methods for profiling the t-cel- receptor repertoire
WO2016100975A1 (en) 2014-12-19 2016-06-23 Massachsetts Institute Ot Technology Molecular biomarkers for cancer immunotherapy
MX2017014700A (es) 2015-05-20 2018-08-15 Broad Inst Inc Neoantigenos compartidos.
TW202241500A (zh) 2015-06-09 2022-11-01 美商博德研究所有限公司 用於贅瘤疫苗之調配物及其製備方法
BR112017027895A2 (pt) 2015-06-23 2018-11-06 Merial Inc vetores virais recombinantes contendo proteínas menores de prrsv e métodos de fabricação e utilização destes
EP3337503A1 (de) 2015-08-20 2018-06-27 Merial, Inc. Fcv-rekombinante impfstoffe und verwendungen davon
EP4286002A3 (de) 2015-09-29 2024-02-28 Boehringer Ingelheim Animal Health USA Inc. Canine parvovirus (cpv)-ähnliche partikelimpfstoffe und verwendungen davon
RU2714428C2 (ru) 2015-11-23 2020-02-14 Мериал, Инк. Слитые белки fmdv-e2 и их применение
RU2626605C2 (ru) * 2015-11-25 2017-07-28 Федеральное Государственное Бюджетное Учреждение Науки Институт Молекулярной Биологии Им. В.А. Энгельгардта Российской Академии Наук (Имб Ран) Генетическая (рекомбинантная) ДНК-конструкция, содержащая кодон-оптимизированный ген гликопротеина (белка G) вируса бешенства с консенсусной аминокислотной последовательностью, которая составлена с учетом аминокислотных последовательностей белка G, выделяемого из штаммов вируса бешенства, циркулирующих на территории Российской Федерации
TWI760322B (zh) 2016-01-29 2022-04-11 美商百靈佳殷格翰動物保健美國有限公司 重組腺病毒載體裝載之fmdv疫苗及其用途
WO2017184590A1 (en) 2016-04-18 2017-10-26 The Broad Institute Inc. Improved hla epitope prediction
US11549149B2 (en) 2017-01-24 2023-01-10 The Broad Institute, Inc. Compositions and methods for detecting a mutant variant of a polynucleotide
CN108704128B (zh) * 2018-05-15 2022-06-21 青岛农业大学 一种犬瘟热细小病毒二联亚单位疫苗
WO2020072700A1 (en) 2018-10-02 2020-04-09 Dana-Farber Cancer Institute, Inc. Hla single allele lines
WO2020131586A2 (en) 2018-12-17 2020-06-25 The Broad Institute, Inc. Methods for identifying neoantigens
RU2707544C1 (ru) * 2018-12-28 2019-11-27 Федеральное Государственное Бюджетное Учреждение Науки Институт Молекулярной Биологии Им. В.А. Энгельгардта Российской Академии Наук (Имб Ран) Генетическая конструкция на основе оптимизированного гена консенсусного гликопротеина вируса бешенства для профилактики бешенства
CN116735873B (zh) * 2023-08-09 2023-10-31 北京纳百生物科技有限公司 特异性结合犬细小病毒vp2蛋白的单克隆抗体在检测试剂中的应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU56248A1 (de) * 1968-06-11 1970-01-15
EP0575491B1 (de) * 1991-03-07 2003-08-13 Virogenetics Corporation Gentechnologisch hergestellter stamm für impfstoffe
EP0740704A1 (de) * 1994-01-27 1996-11-06 University Of Massachusetts Medical Center Immunisierung durch impfung einer dns-transkriptionseinheit
CA2252375C (en) 1996-04-19 2011-12-20 Colpan, Metin Nucleic acid vaccination for parvoviral infections
WO1997041236A1 (en) 1996-04-29 1997-11-06 Andreas Zurbriggen Polynucleotide vaccine against canine distemper
US5846946A (en) 1996-06-14 1998-12-08 Pasteur Merieux Serums Et Vaccins Compositions and methods for administering Borrelia DNA
FR2751227B1 (fr) * 1996-07-19 1998-11-27 Rhone Merieux Formule de vaccin polynucleotidique contre les pathologies canines, notamment les pathologies respiratoires et digestives
CA2223029A1 (en) 1997-02-12 1998-08-12 Akzo Nobel Nv Canine parvovirus dna vaccines
IT1292422B1 (it) * 1997-06-26 1999-02-08 Agip Petroli Reattore a bolle con draft tube e procedimento per la rigenerazione del catalizzatore in esso contenuto
US6063385A (en) * 1997-11-07 2000-05-16 Wisconsin Alumni Research Foundation DNA vaccine for parvovirus

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DE69731309T3 (de) 2015-06-03
KR20060013432A (ko) 2006-02-09
JP2000515521A (ja) 2000-11-21
US6228846B1 (en) 2001-05-08
EP0954332B1 (de) 2004-10-20
CA2260273A1 (en) 1998-01-29
EP0954332B2 (de) 2014-12-31
DE69731309T2 (de) 2005-11-17
CZ300385B6 (cs) 2009-05-06
CZ15899A3 (cs) 1999-05-12
BR9710509A (pt) 1999-08-17
RU2319504C2 (ru) 2008-03-20
AU3699397A (en) 1998-02-10
ZA976284B (en) 1999-01-19
AU733563B2 (en) 2001-05-17
KR100620302B1 (ko) 2006-09-06
TW587942B (en) 2004-05-21
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RU2002132833A (ru) 2005-01-20
PL190150B1 (pl) 2005-11-30
PL331246A1 (en) 1999-07-05
US20010009959A1 (en) 2001-07-26
AR034997A1 (es) 2004-04-14
KR20050087885A (ko) 2005-08-31
FR2751227A1 (fr) 1998-01-23
CA2260273C (en) 2010-12-21
EP0954332A1 (de) 1999-11-10
WO1998003199A1 (fr) 1998-01-29
US6586412B2 (en) 2003-07-01
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FR2751227B1 (fr) 1998-11-27

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